PURINE_METABOLISM

Differential Network Properties
Rewiring Score: 0.219 Mean Expression: 14.124
Gene count: 45 Rewired gene count: 31
Disease Potential: 0.000 Pathway centrality: 0.145
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Gene Symbol Rewiring Score (local) Rewiring Score (Global) Degree Clustering coefficient Betweeness Page Rank Closeness Overall Global centrality
POLR2B 5.134 328.498 26 0.148 0.137 0.132 0.453 0.870
PDE5A 4.467 713.386 29 0.589 0.315 0.165 0.482 1.551
NT5E 0.000 88.004 31 0.180 0.045 0.031 0.481 0.738
ENTPD5 4.869 71.188 31 0.491 0.036 0.018 0.290 0.836
ADK 0.000 721.137 26 0.501 0.306 0.172 0.457 1.437
ADCY2 10.115 582.656 30 0.385 0.265 0.145 0.729 1.525
PDE4A 6.017 287.626 32 0.138 0.136 0.103 0.695 1.073
GMPR 57.463 3789.131 35 0.285 0.875 0.907 0.741 2.807
PRPS2 0.000 30.201 36 0.458 0.017 0.009 0.218 0.702
PDE11A 4.216 4.570 37 0.000 0.003 0.002 0.027 0.032
POLR1B 8.822 323.921 32 0.304 0.154 0.095 0.620 1.173
PNP 8.862 605.057 32 0.318 0.273 0.179 0.553 1.323
XDH 0.000 58.936 32 0.350 0.032 0.023 0.252 0.657
POLR3B 8.949 615.442 27 0.426 0.252 0.155 0.401 1.234
NUDT2 0.000 19.093 39 0.091 0.009 0.013 0.060 0.173
GMPR2 26.809 649.401 30 0.531 0.288 0.159 0.520 1.498
PDE4C 4.314 424.127 32 0.352 0.197 0.122 0.296 0.968
POLR2A 0.000 32.680 34 0.386 0.018 0.009 0.188 0.601
AK5 15.023 1145.103 32 0.367 0.447 0.297 0.741 1.853
FHIT 17.383 1119.441 31 0.477 0.401 0.262 0.685 1.825
AK1 8.404 534.622 30 0.477 0.225 0.134 0.515 1.351
GUCY1B3 4.453 135.069 34 0.108 0.066 0.065 0.377 0.615
NPR1 8.783 329.293 37 0.130 0.171 0.127 0.717 1.146
PDE8B 0.000 6.223 30 0.333 0.003 0.004 0.030 0.372
ADCY3 0.000 25.596 35 0.371 0.013 0.019 0.065 0.468
ADCY6 15.640 1196.694 32 0.541 0.397 0.272 0.637 1.847
ADCY9 23.616 742.162 35 0.372 0.320 0.208 0.646 1.546
PDE6B 0.000 21.529 33 0.538 0.012 0.007 0.132 0.689
APRT 12.209 357.214 31 0.387 0.148 0.099 0.467 1.101
RRM1 18.340 1164.125 26 0.407 0.435 0.282 0.695 1.820
PKLR 7.919 666.373 31 0.564 0.296 0.154 0.457 1.472
POLR1D 0.000 192.539 39 0.109 0.096 0.115 0.471 0.791
NPR2 12.791 1095.500 31 0.418 0.452 0.288 0.637 1.794
PDE9A 4.330 465.487 31 0.229 0.200 0.144 0.696 1.269
PAPSS1 3.943 34.639 30 0.190 0.015 0.021 0.080 0.306
PDE7B 0.000 129.801 31 0.498 0.061 0.045 0.347 0.951
NUDT9 8.936 252.771 33 0.381 0.121 0.071 0.448 1.021
ENTPD3 17.657 895.025 28 0.552 0.369 0.203 0.545 1.670
POLE 0.000 172.349 31 0.097 0.080 0.104 0.486 0.767
AMPD3 9.498 893.450 25 0.501 0.359 0.210 0.552 1.622
NME5 31.584 2255.136 30 0.487 0.616 0.511 0.565 2.179
ENTPD2 0.000 57.575 33 0.308 0.031 0.020 0.252 0.611
PDE2A 19.106 1763.957 33 0.423 0.615 0.410 0.515 1.963
NT5C2 4.304 138.793 27 0.324 0.069 0.069 0.237 0.699