TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY

Differential Network Properties
Rewiring Score: 0.390 Mean Expression: 11.641
Gene count: 35 Rewired gene count: 12
Disease Potential: 0.084 Pathway centrality: 0.090
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Gene Symbol Rewiring Score (local) Rewiring Score (Global) Degree Clustering coefficient Betweeness Page Rank Closeness Overall Global centrality
NFKB1 0.000 7.512 32 0.167 0.003 0.004 0.024 0.198
MAPK1 0.000 90.822 27 0.286 0.044 0.031 0.287 0.648
TLR5 9.686 1737.459 26 0.436 0.603 0.386 0.487 1.912
MAP2K7 0.000 18.047 23 0.200 0.009 0.010 0.105 0.325
IRF5 0.000 194.366 28 0.281 0.094 0.073 0.502 0.951
FOS 0.000 40.179 30 0.208 0.019 0.018 0.109 0.353
TNF 4.941 365.493 29 0.210 0.173 0.101 0.675 1.159
IKBKE 0.000 47.862 32 0.276 0.026 0.017 0.240 0.558
TICAM1 9.308 343.558 29 0.310 0.157 0.087 0.527 1.082
IRF3 3.977 243.765 27 0.179 0.111 0.082 0.603 0.975
CTSK 0.000 1550.044 26 0.333 0.500 0.383 0.778 1.995
MAP2K3 14.069 580.507 25 0.204 0.245 0.176 0.665 1.289
MYD88 9.513 1355.404 27 0.482 0.478 0.320 0.580 1.861
TOLLIP 9.645 622.216 28 0.190 0.244 0.178 0.753 1.364
PIK3R1 0.000 99.582 25 0.222 0.047 0.042 0.159 0.470
IKBKB 0.000 43.302 27 0.100 0.023 0.039 0.137 0.299
IFNAR1 0.000 92.567 27 0.444 0.051 0.027 0.242 0.764
IRF7 0.000 769.632 30 0.247 0.342 0.211 0.638 1.439
MAPK13 0.000 568.028 24 0.477 0.233 0.138 0.435 1.282
TLR7 0.000 39.760 27 0.275 0.021 0.016 0.141 0.453
TRAF6 9.137 1424.146 30 0.347 0.539 0.368 0.595 1.849
MAPK11 0.000 229.869 22 0.098 0.116 0.083 0.611 0.908
RAC1 0.000 51.671 24 0.216 0.027 0.015 0.283 0.541
FADD 19.688 1503.670 27 0.381 0.597 0.367 0.559 1.903
CD14 0.000 4.710 27 0.333 0.003 0.001 0.044 0.381
AKT2 0.000 33.919 29 0.481 0.018 0.010 0.179 0.688
CD86 13.711 904.040 31 0.426 0.391 0.233 0.685 1.734
JUN 0.000 197.753 27 0.312 0.094 0.071 0.448 0.925
MAP2K4 4.408 783.336 19 0.426 0.349 0.201 0.481 1.458
TLR3 0.000 360.137 25 0.496 0.173 0.088 0.514 1.272
MAP3K8 5.278 1222.070 23 0.529 0.441 0.274 0.477 1.721
PIK3R3 0.000 51.513 29 0.153 0.027 0.022 0.264 0.467
PIK3CB 0.000 366.681 24 0.216 0.157 0.126 0.620 1.119
MAPK10 0.000 12.249 26 0.286 0.006 0.006 0.011 0.308