GNRH_SIGNALING_PATHWAY

Differential Network Properties
Rewiring Score: 3.647 Mean Expression: 21.571
Gene count: 44 Rewired gene count: 24
Disease Potential: 0.154 Pathway centrality: 0.136
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Gene Symbol Rewiring Score (local) Rewiring Score (Global) Degree Clustering coefficient Betweeness Page Rank Closeness Overall Global centrality
CALML5 4.602 781.683 32 0.529 0.328 0.170 0.509 1.535
MAPK11 3.833 229.869 39 0.098 0.116 0.083 0.611 0.908
MAPK13 8.904 568.028 35 0.477 0.233 0.138 0.435 1.282
GNA11 0.000 551.492 30 0.316 0.244 0.144 0.676 1.379
PLA2G6 5.121 373.854 32 0.506 0.167 0.091 0.552 1.316
ADCY2 8.453 582.656 33 0.385 0.265 0.145 0.729 1.525
PRKCB 13.222 1269.401 28 0.414 0.413 0.317 0.752 1.895
PRKACA 0.000 366.991 33 0.304 0.174 0.107 0.596 1.181
MAP2K3 14.177 580.507 36 0.204 0.245 0.176 0.665 1.289
MAPK7 4.029 250.575 34 0.175 0.115 0.076 0.539 0.905
ITPR3 3.877 188.095 32 0.252 0.090 0.071 0.396 0.809
CAMK2G 28.685 2275.146 29 0.466 0.709 0.503 0.533 2.210
PLCB2 19.336 1419.774 30 0.344 0.488 0.343 0.696 1.871
MAP2K7 0.000 18.047 34 0.200 0.009 0.010 0.105 0.325
PLCB3 4.612 26.295 37 0.143 0.013 0.014 0.064 0.234
EGFR 15.933 2079.304 33 0.454 0.634 0.463 0.637 2.189
CAMK2B 0.000 5.867 38 0.000 0.003 0.010 0.037 0.050
HRAS 0.000 208.219 38 0.110 0.101 0.071 0.509 0.791
MAPK1 0.000 90.822 25 0.286 0.044 0.031 0.287 0.648
JMJD7-PLA2G4B 11.090 900.306 32 0.532 0.365 0.201 0.573 1.670
GNRHR 0.000 406.605 31 0.468 0.181 0.100 0.573 1.322
GNRH1 0.000 551.452 35 0.347 0.245 0.176 0.380 1.147
SOS1 0.000 108.936 30 0.300 0.051 0.047 0.218 0.615
ADCY3 0.000 25.596 35 0.371 0.013 0.019 0.065 0.468
MAPK10 0.000 12.249 33 0.286 0.006 0.006 0.011 0.308
CALML3 13.452 1316.853 34 0.423 0.452 0.311 0.539 1.725
ADCY6 10.200 1196.694 30 0.541 0.397 0.272 0.637 1.847
PRKX 0.000 66.174 27 0.290 0.033 0.022 0.298 0.644
CALM3 0.000 115.366 33 0.294 0.059 0.041 0.390 0.784
PLA2G4A 0.000 150.193 26 0.447 0.076 0.048 0.334 0.905
ADCY9 4.464 742.162 31 0.372 0.320 0.208 0.646 1.546
PLA2G1B 0.000 73.803 30 0.354 0.041 0.019 0.334 0.749
PTK2B 0.000 106.324 38 0.173 0.048 0.056 0.261 0.538
RAF1 4.214 226.341 37 0.234 0.103 0.072 0.520 0.929
MAP2K4 3.780 783.336 29 0.426 0.349 0.201 0.481 1.458
PLA2G3 7.785 65.970 33 0.659 0.034 0.015 0.217 0.925
MMP2 9.350 1482.489 34 0.416 0.545 0.371 0.685 2.016
PLD2 0.000 20.970 38 0.269 0.011 0.007 0.162 0.449
JUN 0.000 197.753 32 0.312 0.094 0.071 0.448 0.925
MAP3K4 15.497 1303.986 32 0.449 0.480 0.302 0.545 1.776
CALM1 13.331 756.735 33 0.490 0.277 0.183 0.453 1.403
PLD1 11.761 276.872 35 0.446 0.132 0.079 0.400 1.058
PLA2G2A 0.000 49.164 30 0.484 0.027 0.012 0.224 0.746