MELANOGENESIS

Differential Network Properties
Rewiring Score: 4.373 Mean Expression: 27.482
Gene count: 48 Rewired gene count: 36
Disease Potential: 0.077 Pathway centrality: 0.177
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Gene Symbol Rewiring Score (local) Rewiring Score (Global) Degree Clustering coefficient Betweeness Page Rank Closeness Overall Global centrality
HRAS 0.000 208.219 35 0.110 0.101 0.071 0.509 0.791
MAPK1 8.647 90.822 33 0.286 0.044 0.031 0.287 0.648
CREBBP 13.777 497.217 31 0.416 0.205 0.126 0.580 1.327
PLCB3 0.000 26.295 36 0.143 0.013 0.014 0.064 0.234
CAMK2B 0.000 5.867 39 0.000 0.003 0.010 0.037 0.050
WNT7B 8.969 532.882 34 0.253 0.221 0.165 0.573 1.213
FZD3 4.206 111.859 37 0.139 0.056 0.046 0.415 0.656
WNT5B 39.297 775.846 37 0.239 0.345 0.194 0.836 1.614
PLCB2 38.142 1419.774 31 0.344 0.488 0.343 0.696 1.871
FZD10 28.945 1424.121 34 0.443 0.470 0.321 0.753 1.987
MITF 50.939 3029.072 34 0.320 0.767 0.717 0.604 2.407
KIT 30.661 709.142 40 0.101 0.288 0.218 0.791 1.397
TCF7 0.000 25.367 36 0.044 0.015 0.016 0.154 0.229
CAMK2G 67.648 2275.146 34 0.466 0.709 0.503 0.533 2.210
PRKACA 4.589 366.991 34 0.304 0.174 0.107 0.596 1.181
PRKCB 38.171 1269.401 35 0.414 0.413 0.317 0.752 1.895
GNAI1 38.089 1422.644 35 0.439 0.488 0.330 0.778 2.035
WNT4 22.079 845.608 36 0.503 0.330 0.196 0.515 1.543
TCF7L1 0.000 62.029 38 0.207 0.032 0.028 0.192 0.459
WNT3 9.218 519.209 35 0.438 0.225 0.124 0.377 1.163
EDN1 43.690 1501.911 30 0.470 0.494 0.331 0.604 1.898
FZD9 58.086 1762.691 31 0.330 0.495 0.428 0.779 2.032
ADCY2 19.161 582.656 39 0.385 0.265 0.145 0.729 1.525
TYR 52.106 2808.944 29 0.409 0.704 0.641 0.503 2.257
WNT6 0.000 19.775 39 0.077 0.011 0.008 0.176 0.272
WNT16 27.208 1174.401 33 0.537 0.423 0.261 0.533 1.753
CALML5 28.110 781.683 36 0.529 0.328 0.170 0.509 1.535
DCT 14.722 371.259 29 0.381 0.147 0.108 0.481 1.117
ASIP 5.454 386.794 37 0.263 0.170 0.136 0.573 1.142
CALM1 23.926 756.735 39 0.490 0.277 0.183 0.453 1.403
FZD1 40.485 1259.955 31 0.484 0.473 0.297 0.492 1.746
DVL2 17.016 1018.975 36 0.263 0.405 0.306 0.423 1.397
RAF1 4.214 226.341 37 0.234 0.103 0.072 0.520 0.929
TCF7L2 19.110 1194.352 31 0.504 0.413 0.279 0.503 1.699
FZD8 0.000 26.834 38 0.331 0.015 0.009 0.125 0.479
FZD4 30.529 1326.908 30 0.476 0.492 0.309 0.573 1.850
FZD5 0.000 40.856 34 0.169 0.022 0.017 0.272 0.481
POMC 25.854 1212.175 33 0.458 0.419 0.303 0.580 1.759
ADCY9 8.746 742.162 35 0.372 0.320 0.208 0.646 1.546
ADCY6 38.345 1196.694 33 0.541 0.397 0.272 0.637 1.847
CALM3 0.000 115.366 31 0.294 0.059 0.041 0.390 0.784
PRKX 4.502 66.174 38 0.290 0.033 0.022 0.298 0.644
GNAI3 4.129 211.856 29 0.462 0.100 0.061 0.342 0.964
ADCY3 0.000 25.596 35 0.371 0.013 0.019 0.065 0.468
CALML3 23.541 1316.853 40 0.423 0.452 0.311 0.539 1.725
TYRP1 45.140 2185.901 34 0.413 0.647 0.509 0.588 2.157