NF0023650 | cathepsin b

UniProt_ID:

Computed_GO_Component_IDs:
Computed_GO_Components:
Computed_GO_Function_IDs: GO:0008234
Computed_GO_Functions: cysteine-type peptidase activity
Computed_GO_Process_IDs: GO:0006508
Computed_GO_Processes: proteolysis
Curated_GO_Component_IDs:
Curated_GO_Components:
Curated_GO_Function_IDs:
Curated_GO_Functions:
Curated_GO_Processes:

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	NF0023650	SP	0.001740	0.998249	0.000011	CS pos: 29-30. VHA-DV. Pr: 0.9763

No Results

Fasta :-
>NF0023650 MLQQLPPTRPHLIILLILILSYSLVLVHADVPNIPNHSQSSSSSSSYRTNKSESTSSSSF IHQQSLDAFIREINQKAKTWVAGYNKKFGNGRSREEIVNLLLGWNRKSQPLLSKEPLNNR NHHDLELTLPKLSIHTPTRSNSMKISLPANYSSVTNTLYSNCTQLHHIRDQGECGACWAF GVSEMVADRFCIASQTRVNVVLSPQFLLSCDEGDCYGGDIGNTLKYVQNYGIVTNHCIPF LAKIGSNLPCPNRCLDGSNYKLRYKVKNSQQFDLTDIQGMQQSILQNGPIVAAFNVFEDF LHFKGGIYQYTTGGYVGGHVVKVVGWGESMHGIPYWIVANSWSIDWGMNGYFWIIRGKNE CNFESYMWQTTPVL
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/NF0023650.fa Sequence name : NF0023650 Sequence length : 374 VALUES OF COMPUTED PARAMETERS Coef20 : 4.035 CoefTot : -0.761 ChDiff : 5 ZoneTo : 66 KR : 3 DE : 2 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 2.041 2.759 0.404 0.882 MesoH : 0.160 0.336 -0.236 0.395 MuHd_075 : 20.618 16.414 5.228 4.369 MuHd_095 : 24.134 16.628 7.424 5.179 MuHd_100 : 19.748 17.488 6.263 4.384 MuHd_105 : 20.314 16.093 6.874 3.985 Hmax_075 : 2.917 17.033 -2.292 1.318 Hmax_095 : 3.762 4.700 1.097 1.900 Hmax_100 : 6.500 18.100 -0.039 0.670 Hmax_105 : 9.450 6.417 1.419 4.807 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9936 0.0064 DFMC : 0.9796 0.0204

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 374 NF0023650 MLQQLPPTRPHLIILLILILSYSLVLVHADVPNIPNHSQSSSSSSSYRTNKSESTSSSSFIHQQSLDAFIREINQKAKTW 80 VAGYNKKFGNGRSREEIVNLLLGWNRKSQPLLSKEPLNNRNHHDLELTLPKLSIHTPTRSNSMKISLPANYSSVTNTLYS 160 NCTQLHHIRDQGECGACWAFGVSEMVADRFCIASQTRVNVVLSPQFLLSCDEGDCYGGDIGNTLKYVQNYGIVTNHCIPF 240 LAKIGSNLPCPNRCLDGSNYKLRYKVKNSQQFDLTDIQGMQQSILQNGPIVAAFNVFEDFLHFKGGIYQYTTGGYVGGHV 320 VKVVGWGESMHGIPYWIVANSWSIDWGMNGYFWIIRGKNECNFESYMWQTTPVL 400 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ...................................................... 400 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ NF0023650 9 QQLPPTR|PH 0.080 . NF0023650 48 SSSSSYR|TN 0.117 . NF0023650 51 SSYRTNK|SE 0.275 . NF0023650 71 SLDAFIR|EI 0.121 . NF0023650 76 IREINQK|AK 0.072 . NF0023650 78 EINQKAK|TW 0.081 . NF0023650 86 WVAGYNK|KF 0.068 . NF0023650 87 VAGYNKK|FG 0.088 . NF0023650 92 KKFGNGR|SR 0.141 . NF0023650 94 FGNGRSR|EE 0.083 . NF0023650 106 LLLGWNR|KS 0.075 . NF0023650 107 LLGWNRK|SQ 0.081 . NF0023650 114 SQPLLSK|EP 0.058 . NF0023650 120 KEPLNNR|NH 0.092 . NF0023650 131 LELTLPK|LS 0.058 . NF0023650 139 SIHTPTR|SN 0.183 . NF0023650 144 TRSNSMK|IS 0.103 . NF0023650 169 TQLHHIR|DQ 0.148 . NF0023650 189 SEMVADR|FC 0.117 . NF0023650 197 CIASQTR|VN 0.078 . NF0023650 225 DIGNTLK|YV 0.074 . NF0023650 243 CIPFLAK|IG 0.057 . NF0023650 253 NLPCPNR|CL 0.086 . NF0023650 261 LDGSNYK|LR 0.060 . NF0023650 263 GSNYKLR|YK 0.141 . NF0023650 265 NYKLRYK|VK 0.060 . NF0023650 267 KLRYKVK|NS 0.072 . NF0023650 304 EDFLHFK|GG 0.068 . NF0023650 322 VGGHVVK|VV 0.121 . NF0023650 356 GYFWIIR|GK 0.084 . NF0023650 358 FWIIRGK|NE 0.060 . ____________________________^_________________

Fasta :-
>NF0023650 ATGTTGCAACAACTACCACCCACACGTCCTCACCTCATCATCCTCCTCATCCTCATCCTC TCTTACTCACTAGTCCTCGTCCATGCAGATGTTCCGAACATTCCGAACCACTCGCAATCG TCCTCTTCATCCTCTTCCTACAGAACTAACAAGTCGGAATCAACATCATCATCATCCTTT ATTCATCAACAATCTCTTGATGCCTTCATTCGGGAAATTAATCAAAAAGCCAAGACATGG GTGGCTGGTTACAATAAGAAATTTGGAAATGGAAGATCGAGAGAGGAAATTGTGAACTTG TTGTTGGGATGGAATAGAAAATCACAACCATTATTATCAAAAGAACCATTAAATAATAGG AATCATCATGATTTGGAATTGACATTGCCTAAATTGTCCATTCATACACCAACGAGATCA AATTCAATGAAAATCTCTCTTCCTGCGAACTATAGCTCAGTAACAAATACCTTGTATTCC AATTGCACTCAATTGCATCATATTCGAGATCAAGGAGAATGCGGAGCTTGTTGGGCTTTC GGAGTTTCGGAAATGGTCGCCGATCGATTCTGTATTGCCTCTCAAACTAGAGTGAATGTT GTGTTGAGTCCTCAATTCTTATTGAGTTGTGATGAAGGAGATTGTTATGGAGGAGATATT GGAAACACACTTAAATACGTTCAAAATTATGGAATTGTCACTAATCATTGCATTCCATTT TTAGCTAAAATCGGAAGTAATTTACCATGTCCCAATCGATGTTTGGACGGAAGTAATTAC AAATTAAGATACAAAGTGAAAAATTCACAACAGTTTGATTTGACTGATATTCAAGGAATG CAACAAAGTATTTTACAAAATGGTCCCATTGTTGCTGCATTTAATGTTTTTGAAGATTTT TTACATTTCAAAGGAGGAATTTATCAATACACGACTGGAGGTTATGTGGGAGGTCATGTC GTGAAAGTTGTTGGATGGGGAGAAAGTATGCATGGAATTCCTTATTGGATTGTTGCTAAT AGTTGGAGTATTGATTGGGGAATGAATGGATATTTTTGGATCATTCGAGGAAAGAATGAA TGTAATTTTGAAAGTTACATGTGGCAAACCACTCCTGTTTTATAA
Download Fasta

Fasta :-

MLQQLPPTRPHLIILLILILSYSLVLVHADVPNIPNHSQSSSSSSSYRTNKSESTSSSSF IHQQSLDAFIREINQKAKTWVAGYNKKFGNGRSREEIVNLLLGWNRKSQPLLSKEPLNNR NHHDLELTLPKLSIHTPTRSNSMKISLPANYSSVTNTLYSNCTQLHHIRDQGECGACWAF GVSEMVADRFCIASQTRVNVVLSPQFLLSCDEGDCYGGDIGNTLKYVQNYGIVTNHCIPF LAKIGSNLPCPNRCLDGSNYKLRYKVKNSQQFDLTDIQGMQQSILQNGPIVAAFNVFEDF LHFKGGIYQYTTGGYVGGHVVKVVGWGESMHGIPYWIVANSWSIDWGMNGYFWIIRGKNE CNFESYMWQTTPVL

SCOPe

title: active site
coordinates: Q171,C177,H331,N340

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	NF0023650	T	49	0.578	0.068	NF0023650	S	44	0.561	0.023	NF0023650	S	46	0.547	0.036	NF0023650	S	45	0.540	0.015	NF0023650	S	43	0.527	0.023	NF0023650	T	55	0.517	0.038	NF0023650	S	42	0.512	0.020

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	NF0023650	T	49	0.578	0.068	NF0023650	S	44	0.561	0.023	NF0023650	S	46	0.547	0.036	NF0023650	S	45	0.540	0.015	NF0023650	S	43	0.527	0.023	NF0023650	T	55	0.517	0.038	NF0023650	S	42	0.512	0.020

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	NF0023650	46 S	SSSSSYRTN	0.995	unsp	NF0023650	46 S	SSSSSYRTN	0.995	unsp	NF0023650	46 S	SSSSSYRTN	0.995	unsp	NF0023650	54 S	NKSESTSSS	0.996	unsp	NF0023650	142 S	TRSNSMKIS	0.993	unsp	NF0023650	43 S	QSSSSSSSY	0.991	unsp	NF0023650	45 S	SSSSSSYRT	0.991	unsp

NF0023650 | cathepsin b

ID's

UniProt_ID:

GEO Functions

Computed_GO_Component_IDs:

Computed_GO_Components:

Computed_GO_Function_IDs: GO:0008234

Computed_GO_Functions: cysteine-type peptidase activity

Computed_GO_Process_IDs: GO:0006508

Computed_GO_Processes: proteolysis

Curated_GO_Component_IDs:

Curated_GO_Components:

Curated_GO_Function_IDs:

Curated_GO_Functions:

Curated_GO_Processes:

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

SCOPe

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India