PVX_119490 | ATP-dependent Clp protease proteolytic subunit, putative

UniProt_ID: A5KB90

Computed_GO_Component_IDs: GO:0020011
Computed_GO_Components: apicoplast
Computed_GO_Function_IDs: GO:0008462 GO:0004252
Computed_GO_Functions: obsolete endopeptidase Clp activity serine-type endopeptidase activity
Computed_GO_Process_IDs: GO:0030163 GO:0006508
Computed_GO_Processes: protein catabolic process proteolysis
Curated_GO_Component_IDs:
Curated_GO_Components:
Curated_GO_Function_IDs:
Curated_GO_Functions:
Curated_GO_Processes:

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	PVX_119490	SP	0.308919	0.614260	0.076821	CS pos: 20-21. THA-KR. Pr: 0.9633

No Results

Fasta :-
>PVX_119490 MVCLLSLLLFTLLRNNKTHAKRSAHRLSAAPFIQFPGGGVPQGKARRNWAERGSGCSGVY GRRIKARGASSNSLPRSIGDDQECAAPGEESASHSAAERAAYGMAPSDPPAKGMKSVKNG ELRMDAATGVGGFLVGEGAHIEEPPPEGKQTHKGSSGRSGRSSSHRRYRRREGLLPRVNH IKDMKKDVKLFFFKKRIIYLTEEINKKTADELISQLLYLDSLNHDDIKIYINSPGGSINE GLAILDIFNYIQSDIQTISFGLVASMASVILASGKKGKRKSLPNCRIMIHQPLGNAFGHP QDIEIQTKEILYLKKLLYNYLSSFTNQTIETIEKDSDRDHYMNALEAKRYGIIDEVIQTK LPHPYFGGAVESGSG
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/PVX_119490.fa Sequence name : PVX_119490 Sequence length : 375 VALUES OF COMPUTED PARAMETERS Coef20 : 4.723 CoefTot : -1.094 ChDiff : 14 ZoneTo : 79 KR : 14 DE : 1 CleavSite : 86 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 1.971 1.829 0.343 0.655 MesoH : -0.420 0.445 -0.330 0.287 MuHd_075 : 46.559 25.538 10.580 11.273 MuHd_095 : 42.737 22.761 9.271 9.732 MuHd_100 : 36.494 22.894 8.783 8.306 MuHd_105 : 33.999 18.846 9.375 7.570 Hmax_075 : 10.850 15.633 -0.489 5.300 Hmax_095 : 9.800 8.662 1.717 2.975 Hmax_100 : 9.500 10.700 1.824 3.580 Hmax_105 : 7.233 5.075 0.934 2.180 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.0013 0.9987 DFMC : 0.0011 0.9989 This protein is probably imported in mitochondria. f(Ser) = 0.1139 f(Arg) = 0.1266 CMi = 0.46083 CMi is the Chloroplast/Mitochondria Index It has been proposed by Von Heijne et al (Eur J Biochem,1989, 180: 535-545)

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 375 PVX_119490 MVCLLSLLLFTLLRNNKTHAKRSAHRLSAAPFIQFPGGGVPQGKARRNWAERGSGCSGVYGRRIKARGASSNSLPRSIGD 80 DQECAAPGEESASHSAAERAAYGMAPSDPPAKGMKSVKNGELRMDAATGVGGFLVGEGAHIEEPPPEGKQTHKGSSGRSG 160 RSSSHRRYRRREGLLPRVNHIKDMKKDVKLFFFKKRIIYLTEEINKKTADELISQLLYLDSLNHDDIKIYINSPGGSINE 240 GLAILDIFNYIQSDIQTISFGLVASMASVILASGKKGKRKSLPNCRIMIHQPLGNAFGHPQDIEIQTKEILYLKKLLYNY 320 LSSFTNQTIETIEKDSDRDHYMNALEAKRYGIIDEVIQTKLPHPYFGGAVESGSG 400 ................................................................................ 80 ................................................................................ 160 P............................................................................... 240 ................................................................................ 320 ....................................................... 400 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 1 Name Pos Context Score Pred ____________________________v_________________ PVX_119490 14 LLFTLLR|NN 0.070 . PVX_119490 17 TLLRNNK|TH 0.082 . PVX_119490 21 NNKTHAK|RS 0.064 . PVX_119490 22 NKTHAKR|SA 0.350 . PVX_119490 26 AKRSAHR|LS 0.094 . PVX_119490 44 GGVPQGK|AR 0.062 . PVX_119490 46 VPQGKAR|RN 0.140 . PVX_119490 47 PQGKARR|NW 0.127 . PVX_119490 52 RRNWAER|GS 0.189 . PVX_119490 62 CSGVYGR|RI 0.106 . PVX_119490 63 SGVYGRR|IK 0.106 . PVX_119490 65 VYGRRIK|AR 0.142 . PVX_119490 67 GRRIKAR|GA 0.231 . PVX_119490 76 SSNSLPR|SI 0.269 . PVX_119490 99 SHSAAER|AA 0.132 . PVX_119490 112 PSDPPAK|GM 0.068 . PVX_119490 115 PPAKGMK|SV 0.178 . PVX_119490 118 KGMKSVK|NG 0.065 . PVX_119490 123 VKNGELR|MD 0.098 . PVX_119490 149 EPPPEGK|QT 0.072 . PVX_119490 153 EGKQTHK|GS 0.067 . PVX_119490 158 HKGSSGR|SG 0.141 . PVX_119490 161 SSGRSGR|SS 0.625 *ProP* PVX_119490 166 GRSSSHR|RY 0.136 . PVX_119490 167 RSSSHRR|YR 0.225 . PVX_119490 169 SSHRRYR|RR 0.397 . PVX_119490 170 SHRRYRR|RE 0.359 . PVX_119490 171 HRRYRRR|EG 0.124 . PVX_119490 177 REGLLPR|VN 0.083 . PVX_119490 182 PRVNHIK|DM 0.079 . PVX_119490 185 NHIKDMK|KD 0.057 . PVX_119490 186 HIKDMKK|DV 0.138 . PVX_119490 189 DMKKDVK|LF 0.060 . PVX_119490 194 VKLFFFK|KR 0.062 . PVX_119490 195 KLFFFKK|RI 0.092 . PVX_119490 196 LFFFKKR|II 0.206 . PVX_119490 206 LTEEINK|KT 0.063 . PVX_119490 207 TEEINKK|TA 0.125 . PVX_119490 228 LNHDDIK|IY 0.068 . PVX_119490 275 VILASGK|KG 0.055 . PVX_119490 276 ILASGKK|GK 0.121 . PVX_119490 278 ASGKKGK|RK 0.064 . PVX_119490 279 SGKKGKR|KS 0.124 . PVX_119490 280 GKKGKRK|SL 0.168 . PVX_119490 286 KSLPNCR|IM 0.080 . PVX_119490 308 DIEIQTK|EI 0.059 . PVX_119490 314 KEILYLK|KL 0.053 . PVX_119490 315 EILYLKK|LL 0.097 . PVX_119490 334 TIETIEK|DS 0.067 . PVX_119490 338 IEKDSDR|DH 0.094 . PVX_119490 348 MNALEAK|RY 0.085 . PVX_119490 349 NALEAKR|YG 0.122 . PVX_119490 360 DEVIQTK|LP 0.064 . ____________________________^_________________

Fasta :-
>PVX_119490 ACATACATACATGCGCACGTGCTAAGATGCGCGCTTGGTCCCCTCCGCCCGCTTCGCCAA ACTTTTCAAAAGGAACACAGCCGTTTTAAAATTTTTTAGTGGAACGCATCCCCCGCCAGC ACTGCAGAAATGGTATGCTTACTTTCGCTGCTGCTTTTCACCCTGCTGAGAAATAACAAA ACGCATGCAAAAAGGAGTGCACACCGGTTGAGTGCGGCGCCGTTCATACAGTTCCCGGGC GGGGGAGTTCCCCAGGGGAAGGCGAGGCGCAACTGGGCGGAAAGGGGTAGCGGGTGCAGC GGTGTATACGGCCGCCGCATCAAGGCGAGGGGGGCGTCCTCCAACTCGTTGCCGCGGTCG ATAGGGGATGATCAGGAATGCGCCGCACCTGGAGAGGAAAGCGCATCGCATAGTGCGGCA GAGAGAGCGGCATATGGGATGGCCCCAAGTGACCCCCCTGCGAAGGGAATGAAAAGTGTT AAGAATGGCGAGTTGCGCATGGATGCTGCCACAGGCGTGGGAGGTTTCCTGGTAGGGGAG GGAGCCCATATAGAAGAGCCCCCCCCCGAAGGAAAGCAAACCCACAAAGGTAGCAGCGGA AGAAGCGGCAGAAGCAGTAGCCACCGAAGGTACAGGAGGAGGGAGGGGCTGCTGCCCCGG GTGAACCACATCAAAGACATGAAGAAGGACGTGAAGCTGTTCTTTTTCAAAAAAAGAATA ATCTACCTGACGGAGGAAATAAACAAAAAAACGGCCGACGAGCTGATCAGCCAGTTGCTA TACCTAGACAGCCTCAACCATGATGATATAAAAATTTATATAAATTCCCCAGGGGGGTCC ATAAATGAGGGACTAGCCATTTTGGACATCTTCAATTATATCCAGTCAGACATACAGACA ATATCCTTTGGCTTAGTAGCATCTATGGCTTCGGTCATTTTAGCTAGCGGAAAAAAGGGG AAGAGGAAATCTCTGCCCAACTGCAGAATTATGATCCATCAGCCTCTGGGAAATGCCTTC GGCCACCCCCAGGATATAGAAATACAGACCAAAGAGATTCTTTATCTGAAGAAGCTGCTG TATAATTACTTGTCCTCTTTTACTAACCAGACAATTGAGACGATTGAGAAGGACTCAGAC AGGGACCACTACATGAATGCGCTGGAGGCGAAGCGGTACGGAATTATTGACGAGGTGATT CAGACGAAGCTGCCGCACCCGTACTTTGGCGGGGCGGTGGAGTCAGGCAGTGGCTGA
Download Fasta

Fasta :-

MVCLLSLLLFTLLRNNKTHAKRSAHRLSAAPFIQFPGGGVPQGKARRNWAERGSGCSGVY GRRIKARGASSNSLPRSIGDDQECAAPGEESASHSAAERAAYGMAPSDPPAKGMKSVKNG ELRMDAATGVGGFLVGEGAHIEEPPPEGKQTHKGSSGRSGRSSSHRRYRRREGLLPRVNH IKDMKKDVKLFFFKKRIIYLTEEINKKTADELISQLLYLDSLNHDDIKIYINSPGGSINE GLAILDIFNYIQSDIQTISFGLVASMASVILASGKKGKRKSLPNCRIMIHQPLGNAFGHP QDIEIQTKEILYLKKLLYNYLSSFTNQTIETIEKDSDRDHYMNALEAKRYGIIDEVIQTK LPHPYFGGAVESGSG

Clp protease, ClpP subunit

title: active site residues
coordinates: S265,H290,D339

	ID	Site	Position	Gscore	Iscore
	PVX_119490	T	151	0.570	0.050

	ID	Site	Position	Gscore	Iscore
	PVX_119490	T	151	0.570	0.050

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	PVX_119490	159 S	SSGRSGRSS	0.993	unsp	PVX_119490	159 S	SSGRSGRSS	0.993	unsp	PVX_119490	159 S	SSGRSGRSS	0.993	unsp	PVX_119490	163 S	SGRSSSHRR	0.995	unsp	PVX_119490	164 S	GRSSSHRRY	0.997	unsp	PVX_119490	336 S	IEKDSDRDH	0.998	unsp	PVX_119490	116 S	KGMKSVKNG	0.996	unsp	PVX_119490	156 S	HKGSSGRSG	0.996	unsp

PVX_119490

PVX_119490 | ATP-dependent Clp protease proteolytic subunit, putative

ID's

UniProt_ID: A5KB90

GEO Functions

Computed_GO_Component_IDs: GO:0020011

Computed_GO_Components: apicoplast

Computed_GO_Function_IDs: GO:0008462 GO:0004252

Computed_GO_Functions: obsolete endopeptidase Clp activity serine-type endopeptidase activity

Computed_GO_Process_IDs: GO:0030163 GO:0006508

Computed_GO_Processes: protein catabolic process proteolysis

Curated_GO_Component_IDs:

Curated_GO_Components:

Curated_GO_Function_IDs:

Curated_GO_Functions:

Curated_GO_Processes:

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Clp protease, ClpP subunit

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India