SPAC19A8.08 | nonsense-mediated decay protein Upf2

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  • Fasta :-

    >SPAC19A8.08 MSREEQIKKLNQYLDNRELAFRAKDGDKNIFHTESQLDSSLKKNTAFMKRCKSSLTSENY DSFIKEIKTLSLKKFIPEITAAIVEGMMKCKATKDILSSVKIVWALNLRFSTAFTGPMLA NLYCALYPNPGYSLCHESYFELKQNENEVSEKDRSSHLLKVRPLLRFLIEFWLNGVVGTP EDFVSYLPSTDSNDKKFRKPWFEEQNLKKPLVVLLFNDLMDTRFGFLLLPVLTSLVRTFS CELFTTEDFEDKETLELVNRLNPVVWRTYLRKSLNSYVDKLEVYCQKRKSLFEELNKQYQ EQSIIRADPNNEKFQRLANFSKSIESEFSSYASLSEVLNRKASEDLLELNFMEKASSGTN SVFNASGERSESANVETAQVWDDREQYFFYEVFPNFNEGSIAEMKSSIYESSQEGIRSSS ENNKKEDDLKDSTGDLNTTQVSSRVDNFLLKLPSMVSLELTNEMALEFYDLNTKASRNRL IKALCTIPRTSSFLVPYYVRLARILSQLSSEFSTSLVDHARHSFKRMIHRKAKHEYDTRL LIVRYISELTKFQLMPFHMVFECYKLCINEFTPFDLEVLALLLESCGRFLLRYPETKLQM QSFLEAIQKKKLASALASQDQLVLENALHFVNPPKRGIIVSKKKSLKEEFLYDLIQIRLK DDNVFPTLLLLRKFDWKDDYQILYNTIMEVWNIKYNSLNALARLLSALYKFHPEFCIHVI DDTLESLFSAVNNSDHVEKQKRLAQARFISELCVIHMLDVRAITNFLFHLLPLEKFESFL TMKASTLTNINNDMFRLRLIVVVLQTCGPSIIRSKTKKTMLTYLLAYQCYFLIQPEMPLD MLYEFEDVIGYVRPSMKVYMHYEEARNALTERLQAISDDWEEDDTRPVFQGANDGDISSN EESVYLPEDISDESETDEESSGLEESDLLDSEDEDIDNEMQLSRELDEEFERLTNESLLT RMHEKNPGFDVPLPLRASSLGSPYVTRNEESASESSHVMFTLLTKRGNKQRSQYLEIPSH SSLVRSTKNQQTEEIMERKRVKEMVLNFE
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  • MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/474 Sequence name : 474 Sequence length : 1049 VALUES OF COMPUTED PARAMETERS Coef20 : 3.561 CoefTot : 0.247 ChDiff : -27 ZoneTo : 3 KR : 1 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 1.429 1.547 0.222 0.526 MesoH : -0.203 0.673 -0.285 0.253 MuHd_075 : 26.666 11.785 5.493 5.741 MuHd_095 : 12.452 13.196 5.599 2.679 MuHd_100 : 9.732 13.736 5.541 2.447 MuHd_105 : 13.045 16.502 6.451 3.348 Hmax_075 : -14.583 -1.167 -6.040 0.408 Hmax_095 : -17.587 -2.900 -6.033 -1.269 Hmax_100 : -20.700 -1.700 -5.481 -1.160 Hmax_105 : -19.367 2.100 -4.278 -0.620 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9568 0.0432 DFMC : 0.9146 0.0854
  • ##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 1049 SPAC19A8.08 MSREEQIKKLNQYLDNRELAFRAKDGDKNIFHTESQLDSSLKKNTAFMKRCKSSLTSENYDSFIKEIKTLSLKKFIPEIT 80 AAIVEGMMKCKATKDILSSVKIVWALNLRFSTAFTGPMLANLYCALYPNPGYSLCHESYFELKQNENEVSEKDRSSHLLK 160 VRPLLRFLIEFWLNGVVGTPEDFVSYLPSTDSNDKKFRKPWFEEQNLKKPLVVLLFNDLMDTRFGFLLLPVLTSLVRTFS 240 CELFTTEDFEDKETLELVNRLNPVVWRTYLRKSLNSYVDKLEVYCQKRKSLFEELNKQYQEQSIIRADPNNEKFQRLANF 320 SKSIESEFSSYASLSEVLNRKASEDLLELNFMEKASSGTNSVFNASGERSESANVETAQVWDDREQYFFYEVFPNFNEGS 400 IAEMKSSIYESSQEGIRSSSENNKKEDDLKDSTGDLNTTQVSSRVDNFLLKLPSMVSLELTNEMALEFYDLNTKASRNRL 480 IKALCTIPRTSSFLVPYYVRLARILSQLSSEFSTSLVDHARHSFKRMIHRKAKHEYDTRLLIVRYISELTKFQLMPFHMV 560 FECYKLCINEFTPFDLEVLALLLESCGRFLLRYPETKLQMQSFLEAIQKKKLASALASQDQLVLENALHFVNPPKRGIIV 640 SKKKSLKEEFLYDLIQIRLKDDNVFPTLLLLRKFDWKDDYQILYNTIMEVWNIKYNSLNALARLLSALYKFHPEFCIHVI 720 DDTLESLFSAVNNSDHVEKQKRLAQARFISELCVIHMLDVRAITNFLFHLLPLEKFESFLTMKASTLTNINNDMFRLRLI 800 VVVLQTCGPSIIRSKTKKTMLTYLLAYQCYFLIQPEMPLDMLYEFEDVIGYVRPSMKVYMHYEEARNALTERLQAISDDW 880 EEDDTRPVFQGANDGDISSNEESVYLPEDISDESETDEESSGLEESDLLDSEDEDIDNEMQLSRELDEEFERLTNESLLT 960 RMHEKNPGFDVPLPLRASSLGSPYVTRNEESASESSHVMFTLLTKRGNKQRSQYLEIPSHSSLVRSTKNQQTEEIMERKR 1040 VKEMVLNFE 1120 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ................................................................................ 480 ................................................................................ 560 ................................................................................ 640 ................................................................................ 720 ................................................................................ 800 ................................................................................ 880 ................................................................................ 960 ................................................................................ 1040 ......... 1120 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ SPAC19A8.08 3 ----MSR|EE 0.075 . SPAC19A8.08 8 SREEQIK|KL 0.083 . SPAC19A8.08 9 REEQIKK|LN 0.076 . SPAC19A8.08 17 NQYLDNR|EL 0.068 . SPAC19A8.08 22 NRELAFR|AK 0.093 . SPAC19A8.08 24 ELAFRAK|DG 0.093 . SPAC19A8.08 28 RAKDGDK|NI 0.072 . SPAC19A8.08 42 QLDSSLK|KN 0.061 . SPAC19A8.08 43 LDSSLKK|NT 0.108 . SPAC19A8.08 49 KNTAFMK|RC 0.068 . SPAC19A8.08 50 NTAFMKR|CK 0.175 . SPAC19A8.08 52 AFMKRCK|SS 0.089 . SPAC19A8.08 65 NYDSFIK|EI 0.054 . SPAC19A8.08 68 SFIKEIK|TL 0.064 . SPAC19A8.08 73 IKTLSLK|KF 0.060 . SPAC19A8.08 74 KTLSLKK|FI 0.106 . SPAC19A8.08 89 IVEGMMK|CK 0.058 . SPAC19A8.08 91 EGMMKCK|AT 0.091 . SPAC19A8.08 94 MKCKATK|DI 0.080 . SPAC19A8.08 101 DILSSVK|IV 0.067 . SPAC19A8.08 109 VWALNLR|FS 0.082 . SPAC19A8.08 143 ESYFELK|QN 0.069 . SPAC19A8.08 152 ENEVSEK|DR 0.076 . SPAC19A8.08 154 EVSEKDR|SS 0.141 . SPAC19A8.08 160 RSSHLLK|VR 0.060 . SPAC19A8.08 162 SHLLKVR|PL 0.085 . SPAC19A8.08 166 KVRPLLR|FL 0.084 . SPAC19A8.08 195 STDSNDK|KF 0.054 . SPAC19A8.08 196 TDSNDKK|FR 0.158 . SPAC19A8.08 198 SNDKKFR|KP 0.112 . SPAC19A8.08 199 NDKKFRK|PW 0.113 . SPAC19A8.08 208 FEEQNLK|KP 0.055 . SPAC19A8.08 209 EEQNLKK|PL 0.095 . SPAC19A8.08 223 NDLMDTR|FG 0.078 . SPAC19A8.08 237 VLTSLVR|TF 0.081 . SPAC19A8.08 252 TEDFEDK|ET 0.058 . SPAC19A8.08 260 TLELVNR|LN 0.080 . SPAC19A8.08 267 LNPVVWR|TY 0.078 . SPAC19A8.08 271 VWRTYLR|KS 0.072 . SPAC19A8.08 272 WRTYLRK|SL 0.124 . SPAC19A8.08 280 LNSYVDK|LE 0.066 . SPAC19A8.08 287 LEVYCQK|RK 0.060 . SPAC19A8.08 288 EVYCQKR|KS 0.127 . SPAC19A8.08 289 VYCQKRK|SL 0.122 . SPAC19A8.08 297 LFEELNK|QY 0.055 . SPAC19A8.08 306 QEQSIIR|AD 0.083 . SPAC19A8.08 313 ADPNNEK|FQ 0.059 . SPAC19A8.08 316 NNEKFQR|LA 0.104 . SPAC19A8.08 322 RLANFSK|SI 0.120 . SPAC19A8.08 340 LSEVLNR|KA 0.118 . SPAC19A8.08 341 SEVLNRK|AS 0.088 . SPAC19A8.08 354 ELNFMEK|AS 0.067 . SPAC19A8.08 369 FNASGER|SE 0.118 . SPAC19A8.08 384 AQVWDDR|EQ 0.076 . SPAC19A8.08 405 GSIAEMK|SS 0.081 . SPAC19A8.08 417 SSQEGIR|SS 0.123 . SPAC19A8.08 424 SSSENNK|KE 0.074 . SPAC19A8.08 425 SSENNKK|ED 0.104 . SPAC19A8.08 430 KKEDDLK|DS 0.078 . SPAC19A8.08 444 TTQVSSR|VD 0.085 . SPAC19A8.08 451 VDNFLLK|LP 0.061 . SPAC19A8.08 474 FYDLNTK|AS 0.052 . SPAC19A8.08 477 LNTKASR|NR 0.066 . SPAC19A8.08 479 TKASRNR|LI 0.099 . SPAC19A8.08 482 SRNRLIK|AL 0.287 . SPAC19A8.08 489 ALCTIPR|TS 0.089 . SPAC19A8.08 500 LVPYYVR|LA 0.070 . SPAC19A8.08 503 YYVRLAR|IL 0.247 . SPAC19A8.08 521 SLVDHAR|HS 0.110 . SPAC19A8.08 525 HARHSFK|RM 0.064 . SPAC19A8.08 526 ARHSFKR|MI 0.461 . SPAC19A8.08 530 FKRMIHR|KA 0.129 . SPAC19A8.08 531 KRMIHRK|AK 0.135 . SPAC19A8.08 533 MIHRKAK|HE 0.204 . SPAC19A8.08 539 KHEYDTR|LL 0.073 . SPAC19A8.08 544 TRLLIVR|YI 0.112 . SPAC19A8.08 551 YISELTK|FQ 0.069 . SPAC19A8.08 565 MVFECYK|LC 0.061 . SPAC19A8.08 588 LLESCGR|FL 0.090 . SPAC19A8.08 592 CGRFLLR|YP 0.135 . SPAC19A8.08 597 LRYPETK|LQ 0.069 . SPAC19A8.08 609 FLEAIQK|KK 0.057 . SPAC19A8.08 610 LEAIQKK|KL 0.126 . SPAC19A8.08 611 EAIQKKK|LA 0.127 . SPAC19A8.08 635 HFVNPPK|RG 0.060 . SPAC19A8.08 636 FVNPPKR|GI 0.215 . SPAC19A8.08 642 RGIIVSK|KK 0.077 . SPAC19A8.08 643 GIIVSKK|KS 0.116 . SPAC19A8.08 644 IIVSKKK|SL 0.160 . SPAC19A8.08 647 SKKKSLK|EE 0.060 . SPAC19A8.08 658 YDLIQIR|LK 0.078 . SPAC19A8.08 660 LIQIRLK|DD 0.064 . SPAC19A8.08 672 PTLLLLR|KF 0.072 . SPAC19A8.08 673 TLLLLRK|FD 0.079 . SPAC19A8.08 677 LRKFDWK|DD 0.088 . SPAC19A8.08 694 MEVWNIK|YN 0.062 . SPAC19A8.08 703 SLNALAR|LL 0.119 . SPAC19A8.08 710 LLSALYK|FH 0.068 . SPAC19A8.08 739 NSDHVEK|QK 0.068 . SPAC19A8.08 741 DHVEKQK|RL 0.070 . SPAC19A8.08 742 HVEKQKR|LA 0.209 . SPAC19A8.08 747 KRLAQAR|FI 0.157 . SPAC19A8.08 761 IHMLDVR|AI 0.092 . SPAC19A8.08 775 HLLPLEK|FE 0.057 . SPAC19A8.08 783 ESFLTMK|AS 0.057 . SPAC19A8.08 796 INNDMFR|LR 0.081 . SPAC19A8.08 798 NDMFRLR|LI 0.106 . SPAC19A8.08 813 CGPSIIR|SK 0.099 . SPAC19A8.08 815 PSIIRSK|TK 0.066 . SPAC19A8.08 817 IIRSKTK|KT 0.066 . SPAC19A8.08 818 IRSKTKK|TM 0.158 . SPAC19A8.08 853 DVIGYVR|PS 0.080 . SPAC19A8.08 857 YVRPSMK|VY 0.073 . SPAC19A8.08 866 MHYEEAR|NA 0.119 . SPAC19A8.08 872 RNALTER|LQ 0.089 . SPAC19A8.08 886 WEEDDTR|PV 0.120 . SPAC19A8.08 944 NEMQLSR|EL 0.100 . SPAC19A8.08 952 LDEEFER|LT 0.085 . SPAC19A8.08 961 NESLLTR|MH 0.094 . SPAC19A8.08 965 LTRMHEK|NP 0.069 . SPAC19A8.08 976 DVPLPLR|AS 0.073 . SPAC19A8.08 987 GSPYVTR|NE 0.088 . SPAC19A8.08 1005 MFTLLTK|RG 0.058 . SPAC19A8.08 1006 FTLLTKR|GN 0.109 . SPAC19A8.08 1009 LTKRGNK|QR 0.133 . SPAC19A8.08 1011 KRGNKQR|SQ 0.199 . SPAC19A8.08 1025 SHSSLVR|ST 0.226 . SPAC19A8.08 1028 SLVRSTK|NQ 0.172 . SPAC19A8.08 1038 TEEIMER|KR 0.072 . SPAC19A8.08 1039 EEIMERK|RV 0.093 . SPAC19A8.08 1040 EIMERKR|VK 0.194 . SPAC19A8.08 1042 MERKRVK|EM 0.064 . ____________________________^_________________

  • Fasta :-

    >SPAC19A8.08 CGTTGTGGAAGAGGACATGTGTCAAATTTATCTACTCACTTTACGCCAACTATCGTCGAC TAGTGTTCTAAACAAGATATGAGAATTGAAGTGCTTTTCAATGCAATTTCGTTAAATTAT GTCAAGAGAAGAACAAATAAAAAAACTTAATCAATATTTGGATAATAGAGAGCTTGCCTT CCGAGCCAAAGATGGTGACAAAAATATATTTCATACTGAGAGCCAGCTGGATTCTTCTCT AAAGAAAAATACAGCATTTATGAAAAGATGTAAGTCCTCATTAACTTCTGAAAATTACGA TTCCTTTATAAAGGAAATAAAAACCCTGTCTTTGAAAAAGTTCATTCCTGAAATTACCGC CGCCATCGTAGAAGGAATGATGAAATGTAAAGCTACTAAAGACATACTGTCGTCAGTCAA AATTGTTTGGGCTCTTAATCTGCGTTTTTCCACGGCTTTTACTGGACCCATGCTGGCCAA CTTATACTGTGCTTTATACCCAAACCCAGGATACTCATTGTGTCACGAATCATACTTTGA ACTAAAGCAAAATGAAAACGAAGTTTCCGAAAAGGACCGTTCCTCTCATTTACTCAAAGT TAGACCGCTCCTTAGGTTTTTGATTGAGTTTTGGTTAAATGGTGTTGTTGGCACTCCTGA GGATTTCGTCTCTTATTTACCTTCTACTGATTCGAATGATAAAAAGTTTCGTAAGCCATG GTTTGAAGAGCAAAATTTAAAAAAACCCTTGGTGGTTCTGCTATTCAATGACCTTATGGA CACAAGATTTGGGTTTCTCTTGTTACCGGTTTTGACATCTTTGGTGAGGACTTTTTCTTG CGAACTTTTCACTACAGAGGATTTTGAAGATAAAGAAACTTTAGAACTAGTTAATCGCCT TAATCCGGTTGTGTGGAGGACTTATTTAAGAAAGTCGTTGAATTCCTACGTAGACAAATT AGAGGTCTACTGCCAAAAGCGAAAATCTCTTTTTGAAGAATTAAACAAACAATATCAAGA GCAAAGCATTATAAGGGCAGATCCAAACAATGAAAAATTCCAGCGCCTTGCTAACTTTTC AAAATCGATCGAGTCTGAATTTTCTTCTTATGCTTCTCTTTCAGAAGTATTGAATAGAAA AGCTTCCGAAGATCTCTTGGAACTCAACTTTATGGAAAAGGCTTCCTCTGGAACTAATAG CGTGTTTAATGCATCAGGCGAAAGGAGTGAGTCTGCCAATGTTGAAACGGCTCAAGTTTG GGATGATAGAGAGCAATATTTTTTTTACGAGGTGTTCCCAAATTTTAATGAAGGTTCTAT AGCTGAAATGAAAAGTAGCATTTACGAATCCAGTCAGGAAGGTATTCGTTCTTCATCTGA AAACAATAAAAAAGAAGATGATCTTAAGGACTCAACGGGCGATCTAAATACAACGCAAGT AAGCTCAAGAGTTGATAACTTCTTGCTAAAATTACCCTCCATGGTTTCCTTAGAACTCAC GAATGAAATGGCCTTGGAGTTTTACGACTTAAATACAAAGGCATCTAGGAATCGACTTAT AAAGGCTTTGTGCACTATCCCTAGGACATCGTCTTTCCTTGTTCCTTATTATGTTCGATT AGCACGTATTCTTTCTCAACTTTCATCAGAGTTTTCCACTTCATTGGTAGATCATGCAAG ACATTCGTTCAAAAGGATGATTCATCGAAAAGCTAAGCACGAATACGATACTAGATTGCT TATTGTTCGTTATATTTCTGAACTTACTAAATTTCAGTTGATGCCTTTCCACATGGTTTT TGAATGCTATAAATTGTGTATAAATGAGTTTACACCATTTGACTTGGAAGTTTTAGCATT ACTTTTAGAAAGTTGTGGGAGATTTCTTCTTCGTTATCCGGAAACCAAGTTGCAAATGCA ATCGTTTTTAGAAGCCATTCAGAAAAAAAAATTGGCTTCTGCGCTTGCCTCTCAAGATCA GCTTGTACTAGAAAATGCTTTACACTTCGTCAATCCGCCAAAGCGTGGTATCATAGTTTC AAAAAAAAAATCATTGAAAGAGGAATTCTTGTACGATTTAATTCAAATTCGTTTAAAAGA TGACAATGTCTTTCCGACCCTTTTACTGCTTAGGAAGTTTGATTGGAAAGACGATTATCA AATTCTGTACAATACAATTATGGAGGTTTGGAATATAAAATATAATTCTTTAAATGCTCT TGCTCGTCTGCTTAGTGCGCTTTATAAGTTCCATCCAGAATTCTGTATTCATGTGATTGA CGATACACTGGAAAGTTTGTTTTCAGCCGTTAATAATTCCGATCATGTGGAGAAGCAAAA AAGATTGGCACAAGCTCGATTTATATCTGAACTTTGTGTCATCCATATGCTCGACGTGCG TGCAATTACAAATTTTTTGTTCCATTTACTACCATTAGAGAAATTTGAATCTTTTTTAAC CATGAAAGCGTCAACATTAACCAATATTAACAATGACATGTTTCGATTAAGACTTATTGT TGTAGTTTTGCAGACTTGTGGACCATCAATCATCCGTTCAAAAACGAAAAAGACGATGCT TACATATCTATTAGCTTATCAGTGTTATTTTCTCATTCAACCAGAAATGCCTTTAGATAT GCTTTATGAATTTGAAGACGTGATAGGATATGTGCGACCTAGCATGAAAGTATACATGCA TTATGAGGAAGCCAGGAATGCTCTAACGGAAAGGCTTCAGGCCATTTCTGATGATTGGGA AGAAGATGATACACGTCCAGTATTCCAGGGTGCTAATGATGGTGATATTAGCTCGAATGA AGAAAGTGTTTATCTGCCGGAAGATATATCAGATGAATCTGAAACAGACGAGGAATCATC GGGATTGGAAGAGTCTGATCTGTTGGATAGTGAAGACGAAGATATTGATAACGAAATGCA ATTAAGTAGAGAGCTTGATGAAGAGTTTGAGCGCCTAACTAATGAAAGCTTACTGACTCG TATGCATGAGAAAAATCCGGGATTTGATGTTCCACTTCCTCTTAGAGCTTCTAGCCTAGG CTCTCCATATGTGACAAGAAATGAGGAATCAGCTAGCGAATCGTCGCACGTGATGTTTAC TTTATTGACCAAAAGGGGAAATAAACAGCGTTCTCAATATTTAGAGATTCCCTCGCATTC TTCGTTGGTCAGGTCTACCAAGAATCAGCAAACTGAAGAAATAATGGAACGGAAACGTGT TAAAGAAATGGTTTTGAACTTCGAATAAGAGAAGCTCTTGTTTATCTTCGTCCTCTAAAT ACCGAAATTCTAAGCCATTGCTGGTAAATTACCTGCTTCGTTTACAACTAGAATAGACGA ACCTTTTGTATAATATTTAGCTTTTTCATTACCAAATCAAAGCTTGCAATTTACTATGGT AGCCTTCTTTAATTATTTACATTCTAAAATATGCAAGCTAATTAGGTACAATACTTTATT AATACC
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IDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethod
SPAC19A8.08290 SQKRKSLFEE0.995unspSPAC19A8.08290 SQKRKSLFEE0.995unspSPAC19A8.08290 SQKRKSLFEE0.995unspSPAC19A8.08323 SNFSKSIESE0.991unspSPAC19A8.08357 SEKASSGTNS0.993unspSPAC19A8.08366 SVFNASGERS0.993unspSPAC19A8.08419 SGIRSSSENN0.995unspSPAC19A8.08443 STQVSSRVDN0.995unspSPAC19A8.08515 SEFSTSLVDH0.992unspSPAC19A8.08523 SHARHSFKRM0.997unspSPAC19A8.08645 SSKKKSLKEE0.997unspSPAC19A8.08855 SYVRPSMKVY0.994unspSPAC19A8.08914 SISDESETDE0.997unspSPAC19A8.08991 SRNEESASES0.991unspSPAC19A8.081026 SSLVRSTKNQ0.992unspSPAC19A8.08150 SENEVSEKDR0.992unspSPAC19A8.08276 SKSLNSYVDK0.994unsp

SPAC19A8.08      



Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India