SPBC106.16 | 20S proteasome complex subunit alpha 4 Pre6

UniProt_ID: Q10329

Computed_GO_Component_IDs: GO:0005839 GO:0019773
Computed_GO_Components: proteasome core complex proteasome core complex, alpha-subunit complex
Computed_GO_Function_IDs: GO:0004175 GO:0004298
Computed_GO_Functions: endopeptidase activity threonine-type endopeptidase activity
Computed_GO_Process_IDs: GO:0051603 GO:0006511
Computed_GO_Processes: proteolysis involved in cellular protein catabolic process ubiquitin-dependent protein catabolic process
Curated_GO_Component_IDs: GO:0005737 GO:0005829 GO:0034399 GO:0005634 GO:0005839 GO:0019773
Curated_GO_Components: cytoplasm cytosol nuclear periphery nucleus proteasome core complex proteasome core complex, alpha-subunit complex
Curated_GO_Function_IDs: GO:0004175
Curated_GO_Functions: endopeptidase activity
Curated_GO_Processes: positive regulation of mitotic metaphase/anaphase transition proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	SPBC106.16	OTHER	0.999609	0.000167	0.000224

No Results

Fasta :-
>SPBC106.16 MSGYDRALSVFSPDGRLLQVEYGQEAVRRGTTAIALRGNECIVIGVERKNVPKLQNVSNF QKIAMVDNHVCLAFAGLNADARILIDKARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYT QSGGVRPFGVSTLIAGFDVGDNTPRVYQTEPAGIYNAWKATAIGRASKAAREYLEKNWKE GLSRDETIHLAVSSLLEVVQTASGNIELAIMDPGKDVEFLHSDKIDTIVKEIQDEKEAEA ARKKSGRSAPGVSTTSTIQ
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/579 Sequence name : 579 Sequence length : 259 VALUES OF COMPUTED PARAMETERS Coef20 : 3.918 CoefTot : -0.295 ChDiff : 0 ZoneTo : 4 KR : 0 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 0.671 1.294 0.027 0.472 MesoH : -0.912 0.182 -0.451 0.132 MuHd_075 : 23.114 9.312 5.353 4.838 MuHd_095 : 19.240 11.061 4.940 5.134 MuHd_100 : 25.759 16.783 5.903 7.589 MuHd_105 : 27.323 19.517 5.651 8.552 Hmax_075 : 11.400 10.400 1.726 4.340 Hmax_095 : 12.200 10.100 1.874 5.240 Hmax_100 : 14.600 12.500 1.850 5.400 Hmax_105 : 4.725 11.600 -0.028 4.480 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9269 0.0731 DFMC : 0.9361 0.0639

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 259 SPBC106.16 MSGYDRALSVFSPDGRLLQVEYGQEAVRRGTTAIALRGNECIVIGVERKNVPKLQNVSNFQKIAMVDNHVCLAFAGLNAD 80 ARILIDKARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYTQSGGVRPFGVSTLIAGFDVGDNTPRVYQTEPAGIYNAWKA 160 TAIGRASKAAREYLEKNWKEGLSRDETIHLAVSSLLEVVQTASGNIELAIMDPGKDVEFLHSDKIDTIVKEIQDEKEAEA 240 ARKKSGRSAPGVSTTSTIQ 320 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................... 320 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ SPBC106.16 6 -MSGYDR|AL 0.102 . SPBC106.16 16 VFSPDGR|LL 0.092 . SPBC106.16 28 YGQEAVR|RG 0.074 . SPBC106.16 29 GQEAVRR|GT 0.203 . SPBC106.16 37 TTAIALR|GN 0.111 . SPBC106.16 48 IVIGVER|KN 0.087 . SPBC106.16 49 VIGVERK|NV 0.110 . SPBC106.16 53 ERKNVPK|LQ 0.071 . SPBC106.16 62 NVSNFQK|IA 0.076 . SPBC106.16 82 GLNADAR|IL 0.122 . SPBC106.16 87 ARILIDK|AR 0.067 . SPBC106.16 89 ILIDKAR|VE 0.089 . SPBC106.16 96 VEAQNHK|LN 0.059 . SPBC106.16 110 SIEYLTR|YV 0.150 . SPBC106.16 118 VAGVQQK|YT 0.080 . SPBC106.16 126 TQSGGVR|PF 0.115 . SPBC106.16 145 VGDNTPR|VY 0.082 . SPBC106.16 159 GIYNAWK|AT 0.079 . SPBC106.16 165 KATAIGR|AS 0.097 . SPBC106.16 168 AIGRASK|AA 0.156 . SPBC106.16 171 RASKAAR|EY 0.123 . SPBC106.16 176 AREYLEK|NW 0.067 . SPBC106.16 179 YLEKNWK|EG 0.054 . SPBC106.16 184 WKEGLSR|DE 0.102 . SPBC106.16 215 AIMDPGK|DV 0.096 . SPBC106.16 224 EFLHSDK|ID 0.057 . SPBC106.16 230 KIDTIVK|EI 0.062 . SPBC106.16 236 KEIQDEK|EA 0.071 . SPBC106.16 242 KEAEAAR|KK 0.082 . SPBC106.16 243 EAEAARK|KS 0.101 . SPBC106.16 244 AEAARKK|SG 0.133 . SPBC106.16 247 ARKKSGR|SA 0.318 . ____________________________^_________________

Fasta :-
>SPBC106.16 TGAATATGTAAGTGTTGGCACTATATGTGCTTATTCTCAATGGTCATTATGATATGGAGA CAAATGGCGACAGCCACATATTAACTTATAATTTTTAATTAAGAAAAATATATAGAACAT TCATACTAGGATTGAGACTTTTTACCTAAATCCAAAATGCTTTGCTTAAAAAGTCCAACG TTTTTATATTATAATTAACGAGACTAAAATTACCCACTATTCATCATAAACCACATACGA ACTTCACCGCAACGCACTAAACAGCATTAACCACGACGCTAATTGCTTACTAGTTCGAAA TCAGCAAAGCGAAACCTACAGATTACCAAGAATTCACCATGTCGGGATATGATCGTGCAT TATCCGTTTTTTCACCAGATGGACGCTTGCTTCAAGTAGAATACGGACAAGAAGCAGTCC GCCGTGGTACCACTGCAATTGCTCTTCGAGGAAATGAGTGTATTGTAATAGGTGTTGAAC GAAAGAATGTTCCTAAACTTCAAAACGTTTCTAATTTCCAAAAAATTGCTATGGTTGATA ACCATGTTTGTCTAGCATTTGCAGGGTTAAATGCCGACGCTAGAATTTTAATTGATAAAG CTCGTGTTGAAGCACAAAACCATAAATTGAATTTGGCAGATCCTGTTTCTATTGAGTATT TAACTCGCTATGTCGCTGGTGTTCAGCAAAAATACACTCAATCTGGTGGTGTACGACCTT TTGGTGTTTCTACCCTTATTGCTGGATTCGACGTTGGTGATAACACTCCACGGGTTTACC AGACAGAGCCTGCTGGTATCTATAATGCATGGAAAGCCACTGCAATCGGCCGTGCTAGTA AGGCTGCTCGTGAATATCTTGAAAAAAATTGGAAAGAAGGACTATCTCGCGACGAGACAA TTCACCTCGCCGTTTCCAGTCTTTTAGAAGTAGTTCAAACCGCTTCTGGAAACATTGAGT TGGCCATCATGGATCCAGGCAAAGATGTAGAATTCTTGCATTCCGATAAAATAGACACTA TTGTTAAAGAGATTCAAGATGAGAAAGAAGCTGAAGCTGCTCGTAAAAAGAGTGGCCGTT CTGCCCCTGGAGTCTCTACAACTTCTACGATTCAATAATGATACCTCTTTTATTTCATTA CATGCAAACCGACTTAAGAATTTCTTGTTTATAAGGTTCATATGTCTTTTCCCTTTTGTT TAGAGAAGCCCTCTTTTCATAATAACATCACTTATGAAAACTCTTTTATTGTAATGATAT TTTTTATTTACGGTGTTGATGAAGCTTATTAGGAGAATATGTTTTCGAGTCCTCTTTTAT TTTCCTGCAAAAAGATTAGTTAAATGTCAAAGACACAATTACTCATTATTACAAATATTA GCTACAAGAATGTGAGTAGGTATATTAAAAATTATTAATTTTAACAATGCA
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Fasta :-

MSGYDRALSVFSPDGRLLQVEYGQEAVRRGTTAIALRGNECIVIGVERKNVPKLQNVSNF QKIAMVDNHVCLAFAGLNADARILIDKARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYT QSGGVRPFGVSTLIAGFDVGDNTPRVYQTEPAGIYNAWKATAIGRASKAAREYLEKNWKE GLSRDETIHLAVSSLLEVVQTASGNIELAIMDPGKDVEFLHSDKIDTIVKEIQDEKEAEA ARKKSGRSAPGVSTTSTIQ

Proteasome subunits

title: active site
coordinates: T31,E47,K49,K62,R165

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	SPBC106.16	T	255	0.643	0.435	SPBC106.16	T	254	0.638	0.071	SPBC106.16	T	257	0.632	0.028	SPBC106.16	S	256	0.554	0.014	SPBC106.16	S	253	0.545	0.056

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	SPBC106.16	T	255	0.643	0.435	SPBC106.16	T	254	0.638	0.071	SPBC106.16	T	257	0.632	0.028	SPBC106.16	S	256	0.554	0.014	SPBC106.16	S	253	0.545	0.056

	ID	Site	Peptide	Score	Method
	SPBC106.16	245 S	ARKKSGRSA	0.996	unsp

SPBC106.16 | 20S proteasome complex subunit alpha 4 Pre6

ID's

UniProt_ID: Q10329

GEO Functions

Computed_GO_Component_IDs: GO:0005839 GO:0019773

Computed_GO_Components: proteasome core complex proteasome core complex, alpha-subunit complex

Computed_GO_Function_IDs: GO:0004175 GO:0004298

Computed_GO_Functions: endopeptidase activity threonine-type endopeptidase activity

Computed_GO_Process_IDs: GO:0051603 GO:0006511

Computed_GO_Processes: proteolysis involved in cellular protein catabolic process ubiquitin-dependent protein catabolic process

Curated_GO_Component_IDs: GO:0005737 GO:0005829 GO:0034399 GO:0005634 GO:0005839 GO:0019773

Curated_GO_Components: cytoplasm cytosol nuclear periphery nucleus proteasome core complex proteasome core complex, alpha-subunit complex

Curated_GO_Function_IDs: GO:0004175

Curated_GO_Functions: endopeptidase activity

Curated_GO_Processes: positive regulation of mitotic metaphase/anaphase transition proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Proteasome subunits

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

SPBC106.16

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India