SPBP8B7.21 | ubiquitin C-terminal hydrolase Ubp3

UniProt_ID: O94269

Computed_GO_Component_IDs:
Computed_GO_Components:
Computed_GO_Function_IDs: GO:0036459
Computed_GO_Functions: thiol-dependent ubiquitinyl hydrolase activity
Computed_GO_Process_IDs: GO:0016579
Computed_GO_Processes: protein deubiquitination
Curated_GO_Component_IDs: GO:0005737 GO:0010494 GO:0005829 GO:0005634
Curated_GO_Components: cytoplasm cytoplasmic stress granule cytosol nucleus
Curated_GO_Function_IDs: GO:0004197 GO:1905538 GO:0004843
Curated_GO_Functions: cysteine-type endopeptidase activity polysome binding thiol-dependent ubiquitin-specific protease activity
Curated_GO_Processes: cytoplasm protein quality control by the ubiquitin-proteasome system protein deubiquitination regulation of ER to Golgi vesicle-mediated transport

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	SPBP8B7.21	OTHER	0.999962	0.000017	0.000021

No Results

Fasta :-
>SPBP8B7.21 MRDLTSATDSASLESDSSRNQFIINSLLPWYSCSEHEFPHRKARKRRSPKNLDWSVSVQM PLVTSKTKESEKSPKSWSAIAKKHVQGDSPVKKSHSVPVPSDRSEKKSFNSSLGELIETY SPSLDAPRPIQPRGFINTGNICFMNSILQALMYCVPFYNLLKQINRMVPYNFERTTPLIE SLTMLSRDFREYSEKFDLQGDSILPEVVYSATKGNPRFEMLQTGEQEDAEEFLNLFLDEL HEEFVRERRHYLLKNDERNPKSDIKISNGIKSGLDSFDDQSSVEASGWTEVGKNKKPVIA RSATVERSPISQIFGGQLRSTLRVPSARDSVLLEPFQPLQLDIQAEDIHSVIDALEHMTA PEILPEWHSSKGNVTATKQMYIESLPPVLILHLKRFFYEASGGTQKNYKPIAYPARLSIP QNVFSPSVRGSIHPEYDLNAVVYHHGTSASGGHYTVDVQQLDKSGWFRIDDTHIHRVPIH DVENSELSADPSLSKLGHGDRVAYLLFYTRRS
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/478 Sequence name : 478 Sequence length : 512 VALUES OF COMPUTED PARAMETERS Coef20 : 4.378 CoefTot : 0.135 ChDiff : -4 ZoneTo : 2 KR : 1 DE : 0 CleavSite : 12 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 1.471 1.547 0.244 0.562 MesoH : -0.552 0.116 -0.374 0.185 MuHd_075 : 8.591 2.577 1.334 2.055 MuHd_095 : 20.623 10.443 4.857 4.183 MuHd_100 : 27.929 12.066 5.917 4.804 MuHd_105 : 30.865 14.003 6.155 5.401 Hmax_075 : 9.333 1.000 -0.043 0.782 Hmax_095 : 1.000 1.700 -1.467 1.050 Hmax_100 : 11.800 7.000 0.972 2.570 Hmax_105 : 3.150 4.300 -1.286 2.010 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.8923 0.1077 DFMC : 0.8554 0.1446

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 512 SPBP8B7.21 MRDLTSATDSASLESDSSRNQFIINSLLPWYSCSEHEFPHRKARKRRSPKNLDWSVSVQMPLVTSKTKESEKSPKSWSAI 80 AKKHVQGDSPVKKSHSVPVPSDRSEKKSFNSSLGELIETYSPSLDAPRPIQPRGFINTGNICFMNSILQALMYCVPFYNL 160 LKQINRMVPYNFERTTPLIESLTMLSRDFREYSEKFDLQGDSILPEVVYSATKGNPRFEMLQTGEQEDAEEFLNLFLDEL 240 HEEFVRERRHYLLKNDERNPKSDIKISNGIKSGLDSFDDQSSVEASGWTEVGKNKKPVIARSATVERSPISQIFGGQLRS 320 TLRVPSARDSVLLEPFQPLQLDIQAEDIHSVIDALEHMTAPEILPEWHSSKGNVTATKQMYIESLPPVLILHLKRFFYEA 400 SGGTQKNYKPIAYPARLSIPQNVFSPSVRGSIHPEYDLNAVVYHHGTSASGGHYTVDVQQLDKSGWFRIDDTHIHRVPIH 480 DVENSELSADPSLSKLGHGDRVAYLLFYTRRS 560 ..............................................P................................. 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ................................................................................ 480 ................................ 560 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 1 Name Pos Context Score Pred ____________________________v_________________ SPBP8B7.21 2 -----MR|DL 0.135 . SPBP8B7.21 19 LESDSSR|NQ 0.107 . SPBP8B7.21 41 EHEFPHR|KA 0.094 . SPBP8B7.21 42 HEFPHRK|AR 0.068 . SPBP8B7.21 44 FPHRKAR|KR 0.295 . SPBP8B7.21 45 PHRKARK|RR 0.091 . SPBP8B7.21 46 HRKARKR|RS 0.259 . SPBP8B7.21 47 RKARKRR|SP 0.767 *ProP* SPBP8B7.21 50 RKRRSPK|NL 0.272 . SPBP8B7.21 66 MPLVTSK|TK 0.064 . SPBP8B7.21 68 LVTSKTK|ES 0.069 . SPBP8B7.21 72 KTKESEK|SP 0.065 . SPBP8B7.21 75 ESEKSPK|SW 0.129 . SPBP8B7.21 82 SWSAIAK|KH 0.083 . SPBP8B7.21 83 WSAIAKK|HV 0.141 . SPBP8B7.21 92 QGDSPVK|KS 0.058 . SPBP8B7.21 93 GDSPVKK|SH 0.239 . SPBP8B7.21 103 VPVPSDR|SE 0.174 . SPBP8B7.21 106 PSDRSEK|KS 0.110 . SPBP8B7.21 107 SDRSEKK|SF 0.205 . SPBP8B7.21 128 PSLDAPR|PI 0.088 . SPBP8B7.21 133 PRPIQPR|GF 0.110 . SPBP8B7.21 162 PFYNLLK|QI 0.063 . SPBP8B7.21 166 LLKQINR|MV 0.100 . SPBP8B7.21 174 VPYNFER|TT 0.093 . SPBP8B7.21 187 SLTMLSR|DF 0.086 . SPBP8B7.21 190 MLSRDFR|EY 0.439 . SPBP8B7.21 195 FREYSEK|FD 0.073 . SPBP8B7.21 213 VVYSATK|GN 0.060 . SPBP8B7.21 217 ATKGNPR|FE 0.084 . SPBP8B7.21 246 LHEEFVR|ER 0.072 . SPBP8B7.21 248 EEFVRER|RH 0.067 . SPBP8B7.21 249 EFVRERR|HY 0.248 . SPBP8B7.21 254 RRHYLLK|ND 0.072 . SPBP8B7.21 258 LLKNDER|NP 0.073 . SPBP8B7.21 261 NDERNPK|SD 0.184 . SPBP8B7.21 265 NPKSDIK|IS 0.066 . SPBP8B7.21 271 KISNGIK|SG 0.082 . SPBP8B7.21 293 GWTEVGK|NK 0.067 . SPBP8B7.21 295 TEVGKNK|KP 0.065 . SPBP8B7.21 296 EVGKNKK|PV 0.126 . SPBP8B7.21 301 KKPVIAR|SA 0.226 . SPBP8B7.21 307 RSATVER|SP 0.163 . SPBP8B7.21 319 IFGGQLR|ST 0.120 . SPBP8B7.21 323 QLRSTLR|VP 0.076 . SPBP8B7.21 328 LRVPSAR|DS 0.137 . SPBP8B7.21 371 PEWHSSK|GN 0.077 . SPBP8B7.21 378 GNVTATK|QM 0.061 . SPBP8B7.21 394 VLILHLK|RF 0.060 . SPBP8B7.21 395 LILHLKR|FF 0.187 . SPBP8B7.21 406 ASGGTQK|NY 0.058 . SPBP8B7.21 409 GTQKNYK|PI 0.063 . SPBP8B7.21 416 PIAYPAR|LS 0.106 . SPBP8B7.21 429 VFSPSVR|GS 0.117 . SPBP8B7.21 463 DVQQLDK|SG 0.066 . SPBP8B7.21 468 DKSGWFR|ID 0.134 . SPBP8B7.21 476 DDTHIHR|VP 0.068 . SPBP8B7.21 495 ADPSLSK|LG 0.054 . SPBP8B7.21 501 KLGHGDR|VA 0.085 . SPBP8B7.21 510 YLLFYTR|RS 0.070 . SPBP8B7.21 511 LLFYTRR|S- 0.230 . ____________________________^_________________

Fasta :-
>SPBP8B7.21 GTTGAACTGAGGAACGAGGTACAGTTCCTAGCTGTATCGATGATCGATACTAATAGCTTC CTATAAACATTGTCAGTTAAAAATATACTGCATCCCGCTATATTGTAGATCGCAAGAGAA AATTGCCGCAGTTCTATGTATCGTTAAACAGATATTCAAACTGCATTGCTGAAACACAAA AAGATATACCGCATAGCAACAGCATAGTTAACATTATTAAAAATTCACGACTATTGTTAT ATTTATCTTTTTTAAAATTTGCTACGTACTTTACTGCTCAGCTTACTTAAAAAAGTCACT TAATTTACTCGTTCATCTTACTTCACCTCCTTGACAATTAATCATTTCAATTATGATCAC ATTAAGACTTGGTTAACGATTGAATTTGCTGCGGCGTAAAATGAGTGACAATATATATTC AAGACCTATATATAGTTCACACAACAGCAGAATATCGAATTTTAAAATTTACTATTTACT TTTCTCTTTTCGTATCACTTTTGTGGTTTAAGATACATATAGTGGTACTTAGATATGTAA ATATACCGTATTCTCTAAAAATAACTAAAGATGGGCATGGACATTCAATAATTAATAATA AAAAAGAACAACTAAAAATAATTAGGAATTTGAGTTAGGCGGTCAAGTGTTTACAGTGGA ATATCACCATAATACACTTGGTGGAATACGAAGAATTAACGAGGTATAGTGTATATTAAA AAAAGTTTTGGACAGTCTTTTGAAGAGCAAAGCGAACGACAGCCAACCATCAAATTAGTA AACAAGAGTTCAATCTTGCTAGAGTGTGCGTATTTCCATGCGAGATTTGACCTCTGCAAC GGACAGCGCGTCTTTGGAAAGTGATTCGTCACGAAATCAATTTATTATCAATTCACTGCT ACCATGGTACTCATGCTCTGAACATGAATTTCCTCATCGAAAGGCTAGAAAAAGGCGTTC GCCTAAGAATTTAGATTGGTCGGTTTCGGTGCAAATGCCTCTGGTCACATCAAAGACGAA AGAGTCTGAAAAATCGCCTAAATCGTGGTCTGCAATTGCGAAAAAGCATGTTCAAGGAGA CTCTCCTGTTAAAAAATCACATTCTGTTCCGGTACCGTCTGACAGGTCTGAGAAAAAAAG TTTCAATTCATCCCTTGGTGAATTGATCGAAACATATTCTCCATCCCTCGATGCACCCCG TCCTATACAGCCTCGGGGTTTTATAAATACCGGAAATATATGTTTTATGAACTCTATTTT ACAGGCACTAATGTATTGTGTTCCATTTTATAATTTACTTAAGCAAATTAACCGGATGGT TCCGTATAATTTTGAACGTACAACACCTCTTATTGAATCGTTGACAATGCTTTCTAGGGA TTTTAGAGAATATTCTGAGAAATTTGATTTACAAGGAGATTCTATTTTGCCAGAAGTGGT ATATTCAGCTACTAAGGGGAATCCTCGATTTGAAATGTTGCAGACCGGCGAACAGGAGGA TGCTGAGGAGTTTTTGAATTTGTTTCTTGACGAATTACATGAAGAATTCGTGCGTGAACG TAGACATTATTTATTAAAAAATGACGAAAGAAATCCAAAATCTGATATCAAAATTTCAAA TGGTATCAAGTCTGGTTTAGATAGTTTTGATGATCAATCTTCTGTAGAAGCTAGTGGCTG GACCGAAGTTGGTAAAAATAAAAAGCCAGTAATTGCTAGATCTGCTACTGTTGAAAGGTC TCCTATAAGCCAAATTTTTGGTGGTCAGCTGCGCTCTACCTTAAGGGTTCCGAGTGCAAG AGATTCTGTTTTGTTAGAACCGTTTCAACCTCTGCAACTCGACATTCAAGCAGAAGATAT ACATTCAGTTATCGATGCGTTGGAGCATATGACCGCCCCTGAAATTTTACCGGAATGGCA TTCGTCGAAAGGAAATGTTACTGCTACCAAGCAAATGTATATAGAGTCACTTCCTCCTGT CTTGATTCTTCACCTTAAACGATTCTTTTACGAAGCATCTGGCGGTACACAGAAAAATTA TAAGCCTATTGCTTATCCTGCTCGCTTGAGTATTCCACAAAACGTTTTCAGCCCTTCTGT TCGTGGTTCCATACATCCGGAATATGATTTGAATGCAGTGGTTTATCATCACGGTACTTC TGCGTCTGGTGGTCATTATACTGTCGATGTTCAGCAACTTGATAAAAGCGGCTGGTTTCG GATTGATGATACACACATTCACCGCGTACCTATTCATGATGTTGAAAACTCCGAACTTTC CGCTGATCCGAGTCTTAGTAAACTTGGTCACGGCGATCGTGTGGCATACTTACTGTTTTA CACACGACGCTCCTAGGTCATCTGGATTCCTTCCTCCCAAAAAAAATTAACCAATAAAAA CCTTAATTGTTTTGTGTATTCTTCAATAAACAACTCAAGGATTTGAGCTAAAACTGGGGA CTACACTTTTTTATAATTCTTTTTGTTTAAAACGTCGGTTAGAAAATTTTATCATATCTT TTTTACATAATTTTCTCAAAAAGGTTCAGCAATTTTTTATTATTTTTTATTTTATGAACT TTAGCTATTTAAGATTACGTTCCCTCTCAATCCCTTTAAACTAATCGGCTTTATAATACA ACCTTTCTAGGAACTTACTCCGAATATACAAGTGAATTTTCATTGCAGCTTTAATGCAGT ATATATTTTAAAACAGTACCAAAAGTAG
Download Fasta

Fasta :-

MRDLTSATDSASLESDSSRNQFIINSLLPWYSCSEHEFPHRKARKRRSPKNLDWSVSVQM PLVTSKTKESEKSPKSWSAIAKKHVQGDSPVKKSHSVPVPSDRSEKKSFNSSLGELIETY SPSLDAPRPIQPRGFINTGNICFMNSILQALMYCVPFYNLLKQINRMVPYNFERTTPLIE SLTMLSRDFREYSEKFDLQGDSILPEVVYSATKGNPRFEMLQTGEQEDAEEFLNLFLDEL HEEFVRERRHYLLKNDERNPKSDIKISNGIKSGLDSFDDQSSVEASGWTEVGKNKKPVIA RSATVERSPISQIFGGQLRSTLRVPSARDSVLLEPFQPLQLDIQAEDIHSVIDALEHMTA PEILPEWHSSKGNVTATKQMYIESLPPVLILHLKRFFYEASGGTQKNYKPIAYPARLSIP QNVFSPSVRGSIHPEYDLNAVVYHHGTSASGGHYTVDVQQLDKSGWFRIDDTHIHRVPIH DVENSELSADPSLSKLGHGDRVAYLLFYTRRS

Ubiquitin carboxyl-terminal hydrolase, UCH

title: Active Site
coordinates: N137,C142,H453,D471

	ID	Site	Position	Gscore	Iscore
	SPBP8B7.21	T	5	0.509	0.067

	ID	Site	Position	Gscore	Iscore
	SPBP8B7.21	T	5	0.509	0.067

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	SPBP8B7.21	48 S	RKRRSPKNL	0.998	unsp	SPBP8B7.21	48 S	RKRRSPKNL	0.998	unsp	SPBP8B7.21	48 S	RKRRSPKNL	0.998	unsp	SPBP8B7.21	70 S	KTKESEKSP	0.997	unsp	SPBP8B7.21	73 S	ESEKSPKSW	0.997	unsp	SPBP8B7.21	76 S	KSPKSWSAI	0.993	unsp	SPBP8B7.21	104 S	PSDRSEKKS	0.991	unsp	SPBP8B7.21	272 S	NGIKSGLDS	0.99	unsp	SPBP8B7.21	276 S	SGLDSFDDQ	0.994	unsp	SPBP8B7.21	326 S	LRVPSARDS	0.998	unsp	SPBP8B7.21	350 S	EDIHSVIDA	0.993	unsp	SPBP8B7.21	6 S	RDLTSATDS	0.992	unsp	SPBP8B7.21	17 S	LESDSSRNQ	0.993	unsp

SPBP8B7.21 | ubiquitin C-terminal hydrolase Ubp3

ID's

UniProt_ID: O94269

GEO Functions

Computed_GO_Component_IDs:

Computed_GO_Components:

Computed_GO_Function_IDs: GO:0036459

Computed_GO_Functions: thiol-dependent ubiquitinyl hydrolase activity

Computed_GO_Process_IDs: GO:0016579

Computed_GO_Processes: protein deubiquitination

Curated_GO_Component_IDs: GO:0005737 GO:0010494 GO:0005829 GO:0005634

Curated_GO_Components: cytoplasm cytoplasmic stress granule cytosol nucleus

Curated_GO_Function_IDs: GO:0004197 GO:1905538 GO:0004843

Curated_GO_Functions: cysteine-type endopeptidase activity polysome binding thiol-dependent ubiquitin-specific protease activity

Curated_GO_Processes: cytoplasm protein quality control by the ubiquitin-proteasome system protein deubiquitination regulation of ER to Golgi vesicle-mediated transport

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Ubiquitin carboxyl-terminal hydrolase, UCH

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

SPBP8B7.21

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India