SPCC965.04c | mitochondrial inner membrane i-AAA protease complex subunit Yme1 (predicted)

UniProt_ID: O59824

Computed_GO_Component_IDs: GO:0016021 GO:0016020
Computed_GO_Components: integral component of membrane membrane
Computed_GO_Function_IDs: GO:0005524 GO:0046872 GO:0004222
Computed_GO_Functions: ATP binding metal ion binding metalloendopeptidase activity
Computed_GO_Process_IDs: GO:0006508
Computed_GO_Processes: proteolysis
Curated_GO_Component_IDs: GO:0031942 GO:0005743 GO:0005739
Curated_GO_Components: i-AAA complex mitochondrial inner membrane mitochondrion
Curated_GO_Function_IDs: GO:0004176
Curated_GO_Functions: ATP-dependent peptidase activity
Curated_GO_Processes: mitochondrial protein catabolic process mitochondrion organization protein quality control for misfolded or incompletely synthesized proteins proteolysis

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	SPCC965.04c	OTHER	0.803100	0.023327	0.173572

No Results

Fasta :-
>SPCC965.04c MSRVLHPIFLFGKTSFLYSGCSKFGGRLFNNSIVHGWLRTRSYALASGLHPLRKQKLAHF EDLANANMSDPYMQAKLYKELADNFPEAIISRYETQGVARNSACDRYYQEALRKKSWSRS LSNNISLSQSSSSPATSSFSDPKAFSAGVPKFTSDTSSTVSSTPSLNHSLQNSMPPSTPT PPPVWAPTIVSSALGTSSKTPVYVVVDEPRFTKFFRIFKFIAGLSVASYFVLLGMSIFAE TSGLNNIMTNTTEQEPMEERAINVRFSDVQGVDEAKEELEEIVDFLRDPTHFTRLGGKLP RGVLLTGPPGTGKTMLARAVAGEANVPFFFMSGSQFDEMYVGVGAKRVRELFAAARKQAP SIIFIDELDAIGQKRNARDAAHMRQTLNQLLVDLDGFSKNEDLAHPVVFIGATNFPESLD PALTRPGRFDRHIHVPLPDVRGRLAILLQHTRHVPLGKDVDLSIIARGTSGFAGADLANL INQAAVYASKNLSTAVSMRDLEWSKDRILMGAERKSAFITPENKLMTAYHEGGHALVALF TKNAMRPYKATIMPRGSSLGMTISLPDMDKDSWTREEYLAMLDVTMGGRAAEELLYGKDK ITSGAHNDIDKATQVARRMVTEFGMSDRIGPVSLEAEMDNLSPATRALVESEIKSLLEAS YERSLSLLKSHKKELDALATALVDYEFLTAEEMNRVVKGDRDLLRNKLS
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/594 Sequence name : 594 Sequence length : 709 VALUES OF COMPUTED PARAMETERS Coef20 : 4.081 CoefTot : -1.171 ChDiff : 3 ZoneTo : 60 KR : 9 DE : 0 CleavSite : 44 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 1.988 1.976 0.349 0.709 MesoH : 0.379 0.624 -0.162 0.328 MuHd_075 : 37.889 29.993 10.754 8.531 MuHd_095 : 41.480 24.488 12.300 8.661 MuHd_100 : 30.457 20.353 9.729 6.079 MuHd_105 : 32.004 20.242 10.513 6.030 Hmax_075 : 15.200 25.550 3.763 8.283 Hmax_095 : 14.963 16.625 4.028 5.310 Hmax_100 : 12.800 11.700 3.170 3.190 Hmax_105 : 13.767 16.333 3.512 5.020 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.0284 0.9716 DFMC : 0.0199 0.9801 This protein is probably imported in mitochondria. f(Ser) = 0.1167 f(Arg) = 0.0833 CMi = 0.62500 CMi is the Chloroplast/Mitochondria Index It has been proposed by Von Heijne et al (Eur J Biochem,1989, 180: 535-545)

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 709 SPCC965.04c MSRVLHPIFLFGKTSFLYSGCSKFGGRLFNNSIVHGWLRTRSYALASGLHPLRKQKLAHFEDLANANMSDPYMQAKLYKE 80 LADNFPEAIISRYETQGVARNSACDRYYQEALRKKSWSRSLSNNISLSQSSSSPATSSFSDPKAFSAGVPKFTSDTSSTV 160 SSTPSLNHSLQNSMPPSTPTPPPVWAPTIVSSALGTSSKTPVYVVVDEPRFTKFFRIFKFIAGLSVASYFVLLGMSIFAE 240 TSGLNNIMTNTTEQEPMEERAINVRFSDVQGVDEAKEELEEIVDFLRDPTHFTRLGGKLPRGVLLTGPPGTGKTMLARAV 320 AGEANVPFFFMSGSQFDEMYVGVGAKRVRELFAAARKQAPSIIFIDELDAIGQKRNARDAAHMRQTLNQLLVDLDGFSKN 400 EDLAHPVVFIGATNFPESLDPALTRPGRFDRHIHVPLPDVRGRLAILLQHTRHVPLGKDVDLSIIARGTSGFAGADLANL 480 INQAAVYASKNLSTAVSMRDLEWSKDRILMGAERKSAFITPENKLMTAYHEGGHALVALFTKNAMRPYKATIMPRGSSLG 560 MTISLPDMDKDSWTREEYLAMLDVTMGGRAAEELLYGKDKITSGAHNDIDKATQVARRMVTEFGMSDRIGPVSLEAEMDN 640 LSPATRALVESEIKSLLEASYERSLSLLKSHKKELDALATALVDYEFLTAEEMNRVVKGDRDLLRNKLS 720 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 .........................................................P...................... 400 ................................................................................ 480 ................................................................................ 560 ................................................................................ 640 ..................................................................... 720 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 1 Name Pos Context Score Pred ____________________________v_________________ SPCC965.04c 3 ----MSR|VL 0.097 . SPCC965.04c 13 PIFLFGK|TS 0.057 . SPCC965.04c 23 LYSGCSK|FG 0.077 . SPCC965.04c 27 CSKFGGR|LF 0.086 . SPCC965.04c 39 IVHGWLR|TR 0.098 . SPCC965.04c 41 HGWLRTR|SY 0.093 . SPCC965.04c 53 SGLHPLR|KQ 0.066 . SPCC965.04c 54 GLHPLRK|QK 0.098 . SPCC965.04c 56 HPLRKQK|LA 0.163 . SPCC965.04c 76 DPYMQAK|LY 0.069 . SPCC965.04c 79 MQAKLYK|EL 0.082 . SPCC965.04c 92 PEAIISR|YE 0.102 . SPCC965.04c 100 ETQGVAR|NS 0.082 . SPCC965.04c 106 RNSACDR|YY 0.143 . SPCC965.04c 113 YYQEALR|KK 0.078 . SPCC965.04c 114 YQEALRK|KS 0.063 . SPCC965.04c 115 QEALRKK|SW 0.237 . SPCC965.04c 119 RKKSWSR|SL 0.164 . SPCC965.04c 143 SSFSDPK|AF 0.087 . SPCC965.04c 151 FSAGVPK|FT 0.089 . SPCC965.04c 199 ALGTSSK|TP 0.060 . SPCC965.04c 210 VVVDEPR|FT 0.082 . SPCC965.04c 213 DEPRFTK|FF 0.116 . SPCC965.04c 216 RFTKFFR|IF 0.088 . SPCC965.04c 219 KFFRIFK|FI 0.115 . SPCC965.04c 260 QEPMEER|AI 0.085 . SPCC965.04c 265 ERAINVR|FS 0.152 . SPCC965.04c 276 QGVDEAK|EE 0.060 . SPCC965.04c 287 EIVDFLR|DP 0.080 . SPCC965.04c 294 DPTHFTR|LG 0.095 . SPCC965.04c 298 FTRLGGK|LP 0.062 . SPCC965.04c 301 LGGKLPR|GV 0.115 . SPCC965.04c 313 GPPGTGK|TM 0.057 . SPCC965.04c 318 GKTMLAR|AV 0.138 . SPCC965.04c 346 YVGVGAK|RV 0.077 . SPCC965.04c 347 VGVGAKR|VR 0.094 . SPCC965.04c 349 VGAKRVR|EL 0.103 . SPCC965.04c 356 ELFAAAR|KQ 0.080 . SPCC965.04c 357 LFAAARK|QA 0.086 . SPCC965.04c 374 LDAIGQK|RN 0.056 . SPCC965.04c 375 DAIGQKR|NA 0.288 . SPCC965.04c 378 GQKRNAR|DA 0.527 *ProP* SPCC965.04c 384 RDAAHMR|QT 0.110 . SPCC965.04c 399 DLDGFSK|NE 0.056 . SPCC965.04c 425 LDPALTR|PG 0.083 . SPCC965.04c 428 ALTRPGR|FD 0.227 . SPCC965.04c 431 RPGRFDR|HI 0.488 . SPCC965.04c 441 VPLPDVR|GR 0.086 . SPCC965.04c 443 LPDVRGR|LA 0.122 . SPCC965.04c 452 ILLQHTR|HV 0.094 . SPCC965.04c 458 RHVPLGK|DV 0.100 . SPCC965.04c 467 DLSIIAR|GT 0.123 . SPCC965.04c 490 AAVYASK|NL 0.072 . SPCC965.04c 499 STAVSMR|DL 0.215 . SPCC965.04c 505 RDLEWSK|DR 0.059 . SPCC965.04c 507 LEWSKDR|IL 0.128 . SPCC965.04c 514 ILMGAER|KS 0.074 . SPCC965.04c 515 LMGAERK|SA 0.135 . SPCC965.04c 524 FITPENK|LM 0.055 . SPCC965.04c 542 LVALFTK|NA 0.066 . SPCC965.04c 546 FTKNAMR|PY 0.084 . SPCC965.04c 549 NAMRPYK|AT 0.166 . SPCC965.04c 555 KATIMPR|GS 0.112 . SPCC965.04c 570 SLPDMDK|DS 0.073 . SPCC965.04c 575 DKDSWTR|EE 0.071 . SPCC965.04c 589 DVTMGGR|AA 0.093 . SPCC965.04c 598 EELLYGK|DK 0.063 . SPCC965.04c 600 LLYGKDK|IT 0.093 . SPCC965.04c 611 AHNDIDK|AT 0.081 . SPCC965.04c 617 KATQVAR|RM 0.096 . SPCC965.04c 618 ATQVARR|MV 0.266 . SPCC965.04c 628 EFGMSDR|IG 0.085 . SPCC965.04c 646 NLSPATR|AL 0.114 . SPCC965.04c 654 LVESEIK|SL 0.062 . SPCC965.04c 663 LEASYER|SL 0.111 . SPCC965.04c 669 RSLSLLK|SH 0.070 . SPCC965.04c 672 SLLKSHK|KE 0.067 . SPCC965.04c 673 LLKSHKK|EL 0.115 . SPCC965.04c 695 TAEEMNR|VV 0.100 . SPCC965.04c 698 EMNRVVK|GD 0.163 . SPCC965.04c 701 RVVKGDR|DL 0.082 . SPCC965.04c 705 GDRDLLR|NK 0.086 . SPCC965.04c 707 RDLLRNK|LS 0.057 . ____________________________^_________________

Fasta :-
>SPCC965.04c ATCTCTATATAGTGGATCTTTGGTTCATACTGTATGTGTATTTGTTACCCATCATTCAAA TATTATGCTCTAAACACTTACCGTTTACCAACAACGTTGAAACCATTGTTTGGGATTTAG CTTTCCAATTTGGCGTGAAAGCACCTTTTTGTATTGCAAAATTTATGTCAAGGGTTTTGC ATCCTATATTTCTTTTCGGAAAGACAAGTTTCTTGTATTCCGGATGCTCAAAATTCGGAG GACGGTTGTTTAACAATAGCATTGTTCATGGATGGCTACGAACTCGGAGCTATGCATTAG CTTCGGGGCTTCATCCCCTTAGAAAACAAAAGCTTGCGCATTTTGAAGATTTGGCAAATG CTAATATGTCAGACCCATATATGCAGGCTAAATTGTATAAGGAGCTAGCTGATAACTTCC CCGAAGCAATTATAAGCCGTTATGAAACACAAGGAGTTGCCAGGAACTCCGCATGTGATC GATATTATCAAGAGGCTTTGCGAAAAAAATCGTGGAGCAGAAGTTTATCGAACAACATAT CCTTATCTCAATCATCTTCTTCACCTGCCACCTCTAGTTTCAGTGATCCAAAAGCATTTT CGGCAGGCGTACCAAAATTCACATCCGATACATCTTCTACCGTTTCCTCGACTCCTTCAC TTAATCATTCTTTGCAAAATTCCATGCCACCTTCGACTCCTACTCCACCTCCGGTATGGG CACCCACGATTGTTTCATCAGCATTGGGCACAAGTAGTAAAACTCCTGTCTATGTGGTAG TTGATGAACCGAGATTTACAAAATTTTTCAGAATTTTTAAATTCATTGCTGGTCTTAGTG TGGCCTCCTATTTTGTTCTTTTAGGAATGAGTATTTTTGCTGAAACTTCAGGTCTTAACA ATATAATGACCAACACTACTGAGCAAGAACCTATGGAGGAGCGAGCTATTAATGTTCGCT TCTCTGATGTTCAAGGTGTTGACGAGGCCAAGGAGGAACTGGAGGAAATCGTTGATTTTT TGCGCGATCCTACTCATTTTACACGGTTGGGAGGTAAATTGCCTAGAGGTGTTTTGCTTA CAGGACCACCCGGAACTGGAAAAACAATGCTTGCTAGGGCTGTTGCTGGAGAGGCAAATG TTCCTTTTTTCTTTATGAGTGGCAGTCAGTTTGACGAAATGTATGTAGGTGTTGGTGCCA AACGAGTTCGAGAATTGTTCGCTGCCGCTAGAAAGCAAGCTCCTTCCATTATATTTATCG ATGAATTGGATGCTATTGGACAAAAAAGAAATGCACGAGACGCCGCTCATATGAGACAGA CTTTGAACCAATTGCTAGTTGATTTAGACGGGTTTTCAAAAAATGAAGATTTAGCTCATC CAGTCGTTTTTATTGGTGCTACGAATTTCCCCGAAAGTTTGGATCCTGCGCTAACTCGTC CAGGGCGTTTCGATCGCCATATACATGTTCCTTTACCCGATGTTAGAGGGCGTCTGGCAA TCTTACTGCAGCATACACGACATGTACCTCTCGGCAAGGATGTCGATCTCAGCATTATTG CAAGAGGAACCTCTGGGTTTGCTGGGGCTGATCTAGCTAACCTAATCAACCAAGCTGCTG TCTATGCCAGTAAAAACTTATCAACCGCAGTCAGTATGCGTGATTTAGAATGGTCAAAAG ATCGAATACTTATGGGTGCTGAAAGAAAAAGTGCATTCATTACTCCAGAAAATAAGCTAA TGACTGCCTATCACGAAGGTGGACATGCATTAGTAGCTTTATTTACCAAAAATGCTATGA GACCCTACAAGGCTACTATTATGCCTAGAGGTAGTAGTTTGGGAATGACGATTTCCTTAC CAGATATGGATAAAGATAGCTGGACGCGTGAAGAATATCTTGCTATGCTTGACGTCACCA TGGGCGGTCGCGCCGCAGAGGAGCTTTTGTACGGAAAAGATAAAATAACGTCTGGTGCAC ATAATGATATAGACAAGGCTACTCAAGTTGCACGCCGTATGGTAACGGAGTTTGGAATGT CTGACCGCATTGGCCCGGTTAGTTTGGAAGCTGAAATGGATAATCTCTCACCTGCTACGA GAGCGCTAGTGGAATCAGAAATCAAGTCTTTGCTTGAGGCGTCATATGAACGTTCATTAT CTTTGCTTAAATCTCACAAGAAAGAGTTAGATGCATTAGCTACTGCTCTAGTCGATTATG AGTTTTTGACCGCTGAAGAGATGAACCGTGTCGTTAAAGGAGACCGTGATTTACTTCGTA ATAAGCTAAGTTAAGCCAAGACTGTTAGAGTCATGGTATAGGAGGATACTCATAATGCTG AGTTAAATTCTTTTGTACAATATGCTGATGATATAATCAAAATCTAAAAAATTTAATGGA ATGACCCCCTTCCATGAGAACGAAGGTTATAAATATTTTACACTCTTTTGGAGTAAGCTT TTTGTAGTTTGGTTAATGAATTTTTGAGCATTCAACA
Download Fasta

Fasta :-

MSRVLHPIFLFGKTSFLYSGCSKFGGRLFNNSIVHGWLRTRSYALASGLHPLRKQKLAHF EDLANANMSDPYMQAKLYKELADNFPEAIISRYETQGVARNSACDRYYQEALRKKSWSRS LSNNISLSQSSSSPATSSFSDPKAFSAGVPKFTSDTSSTVSSTPSLNHSLQNSMPPSTPT PPPVWAPTIVSSALGTSSKTPVYVVVDEPRFTKFFRIFKFIAGLSVASYFVLLGMSIFAE TSGLNNIMTNTTEQEPMEERAINVRFSDVQGVDEAKEELEEIVDFLRDPTHFTRLGGKLP RGVLLTGPPGTGKTMLARAVAGEANVPFFFMSGSQFDEMYVGVGAKRVRELFAAARKQAP SIIFIDELDAIGQKRNARDAAHMRQTLNQLLVDLDGFSKNEDLAHPVVFIGATNFPESLD PALTRPGRFDRHIHVPLPDVRGRLAILLQHTRHVPLGKDVDLSIIARGTSGFAGADLANL INQAAVYASKNLSTAVSMRDLEWSKDRILMGAERKSAFITPENKLMTAYHEGGHALVALF TKNAMRPYKATIMPRGSSLGMTISLPDMDKDSWTREEYLAMLDVTMGGRAAEELLYGKDK ITSGAHNDIDKATQVARRMVTEFGMSDRIGPVSLEAEMDNLSPATRALVESEIKSLLEAS YERSLSLLKSHKKELDALATALVDYEFLTAEEMNRVVKGDRDLLRNKLS

No Results

title: ATP binding site
coordinates: P308,P309,G310,T311,G312,K313,T314,M315,D366,N414

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	SPCC965.04c	T	188	0.696	0.045	SPCC965.04c	T	178	0.649	0.500	SPCC965.04c	T	180	0.597	0.680	SPCC965.04c	S	169	0.588	0.020	SPCC965.04c	S	173	0.585	0.035	SPCC965.04c	T	163	0.575	0.340	SPCC965.04c	S	177	0.554	0.355	SPCC965.04c	S	191	0.550	0.143	SPCC965.04c	T	153	0.543	0.078	SPCC965.04c	S	146	0.519	0.079	SPCC965.04c	T	196	0.514	0.048	SPCC965.04c	S	165	0.505	0.025	SPCC965.04c	S	192	0.501	0.023

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	SPCC965.04c	T	188	0.696	0.045	SPCC965.04c	T	178	0.649	0.500	SPCC965.04c	T	180	0.597	0.680	SPCC965.04c	S	169	0.588	0.020	SPCC965.04c	S	173	0.585	0.035	SPCC965.04c	T	163	0.575	0.340	SPCC965.04c	S	177	0.554	0.355	SPCC965.04c	S	191	0.550	0.143	SPCC965.04c	T	153	0.543	0.078	SPCC965.04c	S	146	0.519	0.079	SPCC965.04c	T	196	0.514	0.048	SPCC965.04c	S	165	0.505	0.025	SPCC965.04c	S	192	0.501	0.023

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	SPCC965.04c	267 S	NVRFSDVQG	0.994	unsp	SPCC965.04c	267 S	NVRFSDVQG	0.994	unsp	SPCC965.04c	267 S	NVRFSDVQG	0.994	unsp	SPCC965.04c	497 S	STAVSMRDL	0.997	unsp	SPCC965.04c	572 S	MDKDSWTRE	0.995	unsp	SPCC965.04c	102 S	VARNSACDR	0.994	unsp	SPCC965.04c	116 S	LRKKSWSRS	0.996	unsp

SPCC965.04c | mitochondrial inner membrane i-AAA protease complex subunit Yme1 (predicted)

ID's

UniProt_ID: O59824

GEO Functions

Computed_GO_Component_IDs: GO:0016021 GO:0016020

Computed_GO_Components: integral component of membrane membrane

Computed_GO_Function_IDs: GO:0005524 GO:0046872 GO:0004222

Computed_GO_Functions: ATP binding metal ion binding metalloendopeptidase activity

Computed_GO_Process_IDs: GO:0006508

Computed_GO_Processes: proteolysis

Curated_GO_Component_IDs: GO:0031942 GO:0005743 GO:0005739

Curated_GO_Components: i-AAA complex mitochondrial inner membrane mitochondrion

Curated_GO_Function_IDs: GO:0004176

Curated_GO_Functions: ATP-dependent peptidase activity

Curated_GO_Processes: mitochondrial protein catabolic process mitochondrion organization protein quality control for misfolded or incompletely synthesized proteins proteolysis

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

SPCC965.04c

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India