YDL122W | ubiquitin-specific protease UBP1

UniProt_ID: P25037

Computed_GO_Component_IDs:
Computed_GO_Components:
Computed_GO_Function_IDs: GO:0008234 GO:0016787 GO:0008233 GO:0036459
Computed_GO_Functions: cysteine-type peptidase activity hydrolase activity peptidase activity thiol-dependent ubiquitinyl hydrolase activity
Computed_GO_Process_IDs: GO:0016579 GO:0006508 GO:0006511
Computed_GO_Processes: protein deubiquitination proteolysis ubiquitin-dependent protein catabolic process
Curated_GO_Component_IDs: GO:0005737 GO:0005783
Curated_GO_Components: cytoplasm endoplasmic reticulum
Curated_GO_Function_IDs: GO:0004197 GO:0004843
Curated_GO_Functions: cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity
Curated_GO_Processes: proteasome-mediated ubiquitin-dependent protein catabolic process protein deubiquitination regulation of proteasomal protein catabolic process

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YDL122W	OTHER	0.999842	0.000075	0.000083

No Results

Fasta :-
>YDL122W MDLFIESKINSLLQFLFGSRQDFLRNFKTWSNNNNNLSIYLLIFGIVVFFYKKPDHLNYI VESVSEMTTNFRNNNSLSRWLPRSKFTHLDEEILKRGGFIAGLVNDGNTCFMNSVLQSLA SSRELMEFLDNNVIRTYEEIEQNEHNEEGNGQESAQDEATHKKNTRKGGKVYGKHKKKLN RKSSSKEDEEKSQEPDITFSVALRDLLSALNAKYYRDKPYFKTNSLLKAMSKSPRKNILL GYDQEDAQEFFQNILAELESNVKSLNTEKLDTTPVAKSELPDDALVGQLNLGEVGTVYIP TEQIDPNSILHDKSIQNFTPFKLMTPLDGITAERIGCLQCGENGGIRYSVFSGLSLNLPN ENIGSTLKLSQLLSDWSKPEIIEGVECNRCALTAAHSHLFGQLKEFEKKPEGSIPEKLIN AVKDRVHQIEEVLAKPVIDDEDYKKLHTANMVRKCSKSKQILISRPPPLLSIHINRSVFD PRTYMIRKNNSKVLFKSRLNLAPWCCDINEINLDARLPMSKKEKAAQQDSSEDENIGGEY YTKLHERFEQEFEDSEEEKEYDDAEGNYASHYNHTKDISNYDPLNGEVDGVTSDDEDEYI EETDALGNTIKKRIIEHSDVENENVKDNEELQEIDNVSLDEPKINVEDQLETSSDEEDVI PAPPINYARSFSTVPATPLTYSLRSVIVHYGTHNYGHYIAFRKYRGCWWRISDETVYVVD EAEVLSTPGVFMLFYEYDFDEETGKMKDDLEAIQSNNEEDDEKEQEQKGVQEPKESQEQG EGEEQEEGQEQMKFERTEDHRDISGKDVN
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YDL122W.fa Sequence name : YDL122W Sequence length : 809 VALUES OF COMPUTED PARAMETERS Coef20 : 4.220 CoefTot : 0.000 ChDiff : -55 ZoneTo : 1 KR : 0 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 1.447 1.818 0.165 0.739 MesoH : -0.613 0.108 -0.375 0.179 MuHd_075 : 8.672 6.914 2.445 2.000 MuHd_095 : 23.367 22.169 6.337 5.283 MuHd_100 : 15.595 16.788 4.073 3.859 MuHd_105 : 6.941 11.477 1.630 2.542 Hmax_075 : 11.200 13.650 1.561 5.518 Hmax_095 : 11.287 18.900 1.812 6.160 Hmax_100 : 10.700 18.800 1.644 5.840 Hmax_105 : 8.900 18.550 1.531 6.183 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9762 0.0238 DFMC : 0.9917 0.0083

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 809 YDL122W MDLFIESKINSLLQFLFGSRQDFLRNFKTWSNNNNNLSIYLLIFGIVVFFYKKPDHLNYIVESVSEMTTNFRNNNSLSRW 80 LPRSKFTHLDEEILKRGGFIAGLVNDGNTCFMNSVLQSLASSRELMEFLDNNVIRTYEEIEQNEHNEEGNGQESAQDEAT 160 HKKNTRKGGKVYGKHKKKLNRKSSSKEDEEKSQEPDITFSVALRDLLSALNAKYYRDKPYFKTNSLLKAMSKSPRKNILL 240 GYDQEDAQEFFQNILAELESNVKSLNTEKLDTTPVAKSELPDDALVGQLNLGEVGTVYIPTEQIDPNSILHDKSIQNFTP 320 FKLMTPLDGITAERIGCLQCGENGGIRYSVFSGLSLNLPNENIGSTLKLSQLLSDWSKPEIIEGVECNRCALTAAHSHLF 400 GQLKEFEKKPEGSIPEKLINAVKDRVHQIEEVLAKPVIDDEDYKKLHTANMVRKCSKSKQILISRPPPLLSIHINRSVFD 480 PRTYMIRKNNSKVLFKSRLNLAPWCCDINEINLDARLPMSKKEKAAQQDSSEDENIGGEYYTKLHERFEQEFEDSEEEKE 560 YDDAEGNYASHYNHTKDISNYDPLNGEVDGVTSDDEDEYIEETDALGNTIKKRIIEHSDVENENVKDNEELQEIDNVSLD 640 EPKINVEDQLETSSDEEDVIPAPPINYARSFSTVPATPLTYSLRSVIVHYGTHNYGHYIAFRKYRGCWWRISDETVYVVD 720 EAEVLSTPGVFMLFYEYDFDEETGKMKDDLEAIQSNNEEDDEKEQEQKGVQEPKESQEQGEGEEQEEGQEQMKFERTEDH 800 RDISGKDVN 880 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ................................................................................ 480 ................................................................................ 560 ................................................................................ 640 ................................................................................ 720 ................................................................................ 800 ......... 880 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ YDL122W 8 DLFIESK|IN 0.060 . YDL122W 20 QFLFGSR|QD 0.062 . YDL122W 25 SRQDFLR|NF 0.098 . YDL122W 28 DFLRNFK|TW 0.097 . YDL122W 52 IVVFFYK|KP 0.060 . YDL122W 53 VVFFYKK|PD 0.071 . YDL122W 72 EMTTNFR|NN 0.069 . YDL122W 79 NNNSLSR|WL 0.097 . YDL122W 83 LSRWLPR|SK 0.217 . YDL122W 85 RWLPRSK|FT 0.067 . YDL122W 95 LDEEILK|RG 0.059 . YDL122W 96 DEEILKR|GG 0.147 . YDL122W 123 QSLASSR|EL 0.092 . YDL122W 135 LDNNVIR|TY 0.190 . YDL122W 162 QDEATHK|KN 0.065 . YDL122W 163 DEATHKK|NT 0.147 . YDL122W 166 THKKNTR|KG 0.118 . YDL122W 167 HKKNTRK|GG 0.103 . YDL122W 170 NTRKGGK|VY 0.069 . YDL122W 174 GGKVYGK|HK 0.065 . YDL122W 176 KVYGKHK|KK 0.058 . YDL122W 177 VYGKHKK|KL 0.101 . YDL122W 178 YGKHKKK|LN 0.098 . YDL122W 181 HKKKLNR|KS 0.131 . YDL122W 182 KKKLNRK|SS 0.153 . YDL122W 186 NRKSSSK|ED 0.067 . YDL122W 191 SKEDEEK|SQ 0.088 . YDL122W 204 TFSVALR|DL 0.135 . YDL122W 213 LSALNAK|YY 0.075 . YDL122W 216 LNAKYYR|DK 0.101 . YDL122W 218 AKYYRDK|PY 0.068 . YDL122W 222 RDKPYFK|TN 0.062 . YDL122W 228 KTNSLLK|AM 0.068 . YDL122W 232 LLKAMSK|SP 0.075 . YDL122W 235 AMSKSPR|KN 0.111 . YDL122W 236 MSKSPRK|NI 0.088 . YDL122W 263 ELESNVK|SL 0.068 . YDL122W 269 KSLNTEK|LD 0.055 . YDL122W 277 DTTPVAK|SE 0.066 . YDL122W 313 NSILHDK|SI 0.084 . YDL122W 322 QNFTPFK|LM 0.060 . YDL122W 334 DGITAER|IG 0.067 . YDL122W 347 GENGGIR|YS 0.087 . YDL122W 368 NIGSTLK|LS 0.053 . YDL122W 378 LLSDWSK|PE 0.068 . YDL122W 389 EGVECNR|CA 0.090 . YDL122W 404 HLFGQLK|EF 0.076 . YDL122W 408 QLKEFEK|KP 0.066 . YDL122W 409 LKEFEKK|PE 0.108 . YDL122W 417 EGSIPEK|LI 0.075 . YDL122W 423 KLINAVK|DR 0.067 . YDL122W 425 INAVKDR|VH 0.116 . YDL122W 435 IEEVLAK|PV 0.097 . YDL122W 444 IDDEDYK|KL 0.066 . YDL122W 445 DDEDYKK|LH 0.077 . YDL122W 453 HTANMVR|KC 0.102 . YDL122W 454 TANMVRK|CS 0.109 . YDL122W 457 MVRKCSK|SK 0.081 . YDL122W 459 RKCSKSK|QI 0.073 . YDL122W 465 KQILISR|PP 0.064 . YDL122W 476 LSIHINR|SV 0.274 . YDL122W 482 RSVFDPR|TY 0.091 . YDL122W 487 PRTYMIR|KN 0.081 . YDL122W 488 RTYMIRK|NN 0.105 . YDL122W 492 IRKNNSK|VL 0.071 . YDL122W 496 NSKVLFK|SR 0.068 . YDL122W 498 KVLFKSR|LN 0.071 . YDL122W 516 EINLDAR|LP 0.078 . YDL122W 521 ARLPMSK|KE 0.062 . YDL122W 522 RLPMSKK|EK 0.121 . YDL122W 524 PMSKKEK|AA 0.084 . YDL122W 543 GGEYYTK|LH 0.065 . YDL122W 547 YTKLHER|FE 0.113 . YDL122W 559 EDSEEEK|EY 0.093 . YDL122W 576 SHYNHTK|DI 0.094 . YDL122W 611 ALGNTIK|KR 0.061 . YDL122W 612 LGNTIKK|RI 0.096 . YDL122W 613 GNTIKKR|II 0.287 . YDL122W 626 VENENVK|DN 0.072 . YDL122W 643 VSLDEPK|IN 0.058 . YDL122W 669 PPINYAR|SF 0.245 . YDL122W 684 PLTYSLR|SV 0.178 . YDL122W 702 GHYIAFR|KY 0.089 . YDL122W 703 HYIAFRK|YR 0.088 . YDL122W 705 IAFRKYR|GC 0.371 . YDL122W 710 YRGCWWR|IS 0.120 . YDL122W 745 FDEETGK|MK 0.068 . YDL122W 747 EETGKMK|DD 0.070 . YDL122W 763 NEEDDEK|EQ 0.069 . YDL122W 768 EKEQEQK|GV 0.074 . YDL122W 774 KGVQEPK|ES 0.074 . YDL122W 793 EGQEQMK|FE 0.070 . YDL122W 796 EQMKFER|TE 0.081 . YDL122W 801 ERTEDHR|DI 0.129 . YDL122W 806 HRDISGK|DV 0.134 . ____________________________^_________________

Fasta :-
>YDL122W ATGGATTTGTTTATTGAAAGCAAGATAAACAGTTTATTACAATTTTTATTTGGTTCCCGA CAGGATTTTTTGAGAAATTTTAAAACTTGGAGTAACAACAATAACAATCTATCGATTTAT TTATTAATTTTTGGCATAGTAGTATTTTTTTATAAAAAACCAGACCATCTAAACTACATT GTTGAGAGCGTTAGTGAAATGACAACAAACTTCAGAAATAATAATAGCCTTAGCCGTTGG TTGCCCAGAAGTAAGTTTACCCACTTAGACGAAGAGATCTTGAAAAGAGGTGGTTTCATT GCTGGTTTAGTTAATGATGGTAACACTTGTTTTATGAACTCTGTTTTGCAATCATTGGCA TCATCCAGAGAATTAATGGAGTTCTTGGACAATAATGTCATAAGGACCTATGAGGAGATA GAACAAAATGAACACAATGAAGAAGGAAACGGGCAAGAATCTGCTCAAGATGAAGCCACT CATAAGAAAAACACTCGTAAGGGTGGCAAAGTTTATGGTAAGCATAAGAAGAAATTGAAT AGGAAGTCAAGTTCGAAAGAAGACGAAGAAAAGAGCCAGGAGCCAGATATCACTTTCAGT GTCGCCTTAAGGGATCTACTTTCTGCCTTAAATGCGAAGTATTATCGGGATAAACCCTAT TTCAAAACCAATAGTTTATTGAAAGCAATGTCCAAATCTCCAAGAAAAAATATTCTTCTT GGCTACGACCAAGAGGACGCGCAAGAATTCTTCCAGAACATACTAGCCGAGTTGGAAAGT AACGTTAAATCATTGAATACTGAAAAACTAGATACCACTCCAGTTGCGAAATCAGAATTA CCCGATGATGCTTTAGTAGGTCAACTTAACCTTGGTGAAGTTGGCACTGTTTACATTCCA ACTGAACAGATTGATCCTAACTCTATACTACATGACAAGTCCATTCAAAATTTCACACCT TTCAAACTAATGACTCCTTTAGATGGTATCACGGCAGAAAGAATTGGTTGTTTACAGTGT GGTGAGAACGGTGGCATAAGATATTCCGTATTTTCGGGATTAAGCTTAAATTTACCGAAC GAGAATATTGGTTCCACTTTAAAATTATCTCAGTTATTAAGCGACTGGAGTAAACCTGAA ATCATCGAAGGCGTAGAATGTAACCGTTGTGCCCTCACAGCAGCGCACTCTCATTTATTT GGTCAGTTGAAAGAATTTGAAAAAAAACCTGAGGGTTCGATCCCAGAAAAGTTAATTAAC GCTGTAAAAGATAGGGTCCATCAAATCGAAGAAGTTCTTGCCAAACCAGTTATTGACGAT GAAGATTATAAGAAGTTGCATACAGCAAATATGGTACGTAAATGCTCTAAATCTAAGCAG ATTTTAATATCAAGACCTCCACCATTATTATCCATTCATATCAACAGATCCGTATTTGAT CCAAGAACGTACATGATTAGAAAAAATAACTCGAAAGTATTGTTTAAGTCAAGGTTGAAT CTTGCCCCATGGTGTTGTGATATTAATGAAATCAATTTGGATGCTCGTTTGCCAATGTCA AAAAAGGAAAAAGCTGCGCAACAAGATTCAAGTGAAGATGAAAACATTGGCGGTGAATAC TATACGAAATTACATGAACGCTTCGAGCAGGAATTTGAAGACAGCGAGGAAGAAAAAGAA TACGATGACGCAGAGGGGAACTATGCGTCTCATTACAATCATACCAAGGATATCAGTAAC TATGATCCCCTAAACGGTGAAGTCGATGGCGTGACATCCGATGATGAAGATGAGTACATT GAAGAAACCGATGCTTTAGGGAATACAATCAAAAAAAGGATCATAGAACATTCTGATGTT GAAAACGAGAATGTAAAAGATAATGAAGAACTGCAAGAAATCGACAATGTGAGCCTTGAC GAACCAAAGATCAATGTTGAAGATCAACTAGAAACATCATCTGATGAGGAAGATGTTATA CCAGCTCCACCTATCAATTATGCTAGGTCATTTTCCACAGTTCCAGCCACTCCATTGACA TATTCATTGCGCTCTGTCATTGTTCACTACGGTACCCATAATTATGGTCATTACATTGCA TTTAGAAAATACAGGGGTTGTTGGTGGAGAATATCTGATGAGACTGTGTACGTTGTGGAC GAAGCTGAAGTCCTTTCAACACCCGGTGTATTTATGTTATTTTACGAATATGACTTTGAT GAAGAAACTGGGAAGATGAAGGATGATTTGGAAGCTATTCAGAGTAATAATGAAGAAGAT GATGAAAAAGAGCAGGAGCAAAAAGGAGTCCAGGAGCCAAAGGAAAGCCAAGAGCAAGGA GAAGGTGAAGAGCAAGAGGAAGGTCAAGAGCAGATGAAGTTCGAGAGAACAGAAGACCAT AGAGATATTTCTGGTAAAGATGTAAACTAA
Download Fasta

Fasta :-

MDLFIESKINSLLQFLFGSRQDFLRNFKTWSNNNNNLSIYLLIFGIVVFFYKKPDHLNYI VESVSEMTTNFRNNNSLSRWLPRSKFTHLDEEILKRGGFIAGLVNDGNTCFMNSVLQSLA SSRELMEFLDNNVIRTYEEIEQNEHNEEGNGQESAQDEATHKKNTRKGGKVYGKHKKKLN RKSSSKEDEEKSQEPDITFSVALRDLLSALNAKYYRDKPYFKTNSLLKAMSKSPRKNILL GYDQEDAQEFFQNILAELESNVKSLNTEKLDTTPVAKSELPDDALVGQLNLGEVGTVYIP TEQIDPNSILHDKSIQNFTPFKLMTPLDGITAERIGCLQCGENGGIRYSVFSGLSLNLPN ENIGSTLKLSQLLSDWSKPEIIEGVECNRCALTAAHSHLFGQLKEFEKKPEGSIPEKLIN AVKDRVHQIEEVLAKPVIDDEDYKKLHTANMVRKCSKSKQILISRPPPLLSIHINRSVFD PRTYMIRKNNSKVLFKSRLNLAPWCCDINEINLDARLPMSKKEKAAQQDSSEDENIGGEY YTKLHERFEQEFEDSEEEKEYDDAEGNYASHYNHTKDISNYDPLNGEVDGVTSDDEDEYI EETDALGNTIKKRIIEHSDVENENVKDNEELQEIDNVSLDEPKINVEDQLETSSDEEDVI PAPPINYARSFSTVPATPLTYSLRSVIVHYGTHNYGHYIAFRKYRGCWWRISDETVYVVD EAEVLSTPGVFMLFYEYDFDEETGKMKDDLEAIQSNNEEDDEKEQEQKGVQEPKESQEQG EGEEQEEGQEQMKFERTEDHRDISGKDVN

No Results

title: Active Site
coordinates: N105,C110,H697,D713

No Results

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YDL122W	185 S	RKSSSKEDE	0.998	unsp	YDL122W	185 S	RKSSSKEDE	0.998	unsp	YDL122W	185 S	RKSSSKEDE	0.998	unsp	YDL122W	477 S	HINRSVFDP	0.991	unsp	YDL122W	520 S	RLPMSKKEK	0.996	unsp	YDL122W	530 S	AQQDSSEDE	0.993	unsp	YDL122W	555 S	EFEDSEEEK	0.995	unsp	YDL122W	618 S	IIEHSDVEN	0.992	unsp	YDL122W	653 S	QLETSSDEE	0.992	unsp	YDL122W	654 S	LETSSDEED	0.991	unsp	YDL122W	804 S	HRDISGKDV	0.997	unsp	YDL122W	183 S	LNRKSSSKE	0.993	unsp	YDL122W	184 S	NRKSSSKED	0.998	unsp

YDL122W | ubiquitin-specific protease UBP1

ID's

UniProt_ID: P25037

GEO Functions

Computed_GO_Component_IDs:

Computed_GO_Components:

Computed_GO_Function_IDs: GO:0008234 GO:0016787 GO:0008233 GO:0036459

Computed_GO_Functions: cysteine-type peptidase activity hydrolase activity peptidase activity thiol-dependent ubiquitinyl hydrolase activity

Computed_GO_Process_IDs: GO:0016579 GO:0006508 GO:0006511

Computed_GO_Processes: protein deubiquitination proteolysis ubiquitin-dependent protein catabolic process

Curated_GO_Component_IDs: GO:0005737 GO:0005783

Curated_GO_Components: cytoplasm endoplasmic reticulum

Curated_GO_Function_IDs: GO:0004197 GO:0004843

Curated_GO_Functions: cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity

Curated_GO_Processes: proteasome-mediated ubiquitin-dependent protein catabolic process protein deubiquitination regulation of proteasomal protein catabolic process

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YDL122W

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India