YDR144C | aspartyl protease

UniProt_ID: P53379

Computed_GO_Component_IDs: GO:0031225 GO:0016020 GO:0005886
Computed_GO_Components: anchored component of membrane membrane plasma membrane
Computed_GO_Function_IDs: GO:0004190 GO:0016787 GO:0008233
Computed_GO_Functions: aspartic-type endopeptidase activity hydrolase activity peptidase activity
Computed_GO_Process_IDs: GO:0006508
Computed_GO_Processes: proteolysis
Curated_GO_Component_IDs: GO:0031362 GO:0005576 GO:0009277 GO:0000324
Curated_GO_Components: anchored component of external side of plasma membrane extracellular region fungal-type cell wall fungal-type vacuole
Curated_GO_Function_IDs: GO:0004190
Curated_GO_Functions: aspartic-type endopeptidase activity
Curated_GO_Processes: fungal-type cell wall organization protein catabolic process proteolysis signal transduction involved in filamentous growth

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YDR144C	SP	0.000475	0.999524	0.000001	CS pos: 22-23. VDA-GV. Pr: 0.9169

No Results

Fasta :-
>YDR144C MKLSVLTFVVDALLVCSSIVDAGVTDFPSLPSNEVYVKMNFQKKYGSSFENALDDTKGRT RLMTRDDDYELVELTNQNSFYSVELDIGTPPQKVTVLVDTGSSDLWVTGSDNPYCSTKKK DTTGSSFKQVNKDALASVVESVFTEISYDTTIVTSEATATFDSTASTSQLIDCATYGTFN TSKSSTFNSNNTEFSIAYGDTTFASGTWGHDQLSLNDLNITGLSFAVANETNSTVGVLGI GLPGLESTYSGVSLSSVQKSYTYNNFPMVLKNSGVIKSTAYSLFANDSDSKHGTILFGAV DHGKYAGDLYTIPIINTLQHRGYKDPIQFQVTLQGLGTSKGDKEDNLTTLTTTKIPVLLD SGTTISYMPTELVKMLADQVGATYSSAYGYYIMDCIKEMEEESSIIFDFGGFYLSNWLSD FQLVTDSRSNICILGIAPQSDPTIILGDNFLANTYVVYDLDNMEISMAQANFSDDGEYIE IIESAVPSALKAPGYSSTWSTYESIVSGGNMFSTAANSSISYFASTSHSATSSSSSKGQK TQTSTTALSISKSTSSTSSTGMLSPTSSSSTRKENGGHNLNPPFFARFITAIFHHI
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YDR144C.fa Sequence name : YDR144C Sequence length : 596 VALUES OF COMPUTED PARAMETERS Coef20 : 4.876 CoefTot : 0.243 ChDiff : -27 ZoneTo : 10 KR : 1 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 1.518 2.200 0.365 0.636 MesoH : 0.325 0.339 -0.240 0.277 MuHd_075 : 19.029 15.043 4.862 4.351 MuHd_095 : 10.734 9.103 3.586 1.893 MuHd_100 : 3.954 9.370 2.194 1.457 MuHd_105 : 6.047 10.737 3.550 1.725 Hmax_075 : 19.600 26.250 4.250 7.163 Hmax_095 : 16.887 17.850 4.009 5.136 Hmax_100 : 18.500 21.600 4.799 6.050 Hmax_105 : 16.200 21.500 4.998 5.610 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9608 0.0392 DFMC : 0.9684 0.0316

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 596 YDR144C MKLSVLTFVVDALLVCSSIVDAGVTDFPSLPSNEVYVKMNFQKKYGSSFENALDDTKGRTRLMTRDDDYELVELTNQNSF 80 YSVELDIGTPPQKVTVLVDTGSSDLWVTGSDNPYCSTKKKDTTGSSFKQVNKDALASVVESVFTEISYDTTIVTSEATAT 160 FDSTASTSQLIDCATYGTFNTSKSSTFNSNNTEFSIAYGDTTFASGTWGHDQLSLNDLNITGLSFAVANETNSTVGVLGI 240 GLPGLESTYSGVSLSSVQKSYTYNNFPMVLKNSGVIKSTAYSLFANDSDSKHGTILFGAVDHGKYAGDLYTIPIINTLQH 320 RGYKDPIQFQVTLQGLGTSKGDKEDNLTTLTTTKIPVLLDSGTTISYMPTELVKMLADQVGATYSSAYGYYIMDCIKEME 400 EESSIIFDFGGFYLSNWLSDFQLVTDSRSNICILGIAPQSDPTIILGDNFLANTYVVYDLDNMEISMAQANFSDDGEYIE 480 IIESAVPSALKAPGYSSTWSTYESIVSGGNMFSTAANSSISYFASTSHSATSSSSSKGQKTQTSTTALSISKSTSSTSST 560 GMLSPTSSSSTRKENGGHNLNPPFFARFITAIFHHI 640 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ................................................................................ 480 ................................................................................ 560 .................................... 640 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ YDR144C 2 -----MK|LS 0.055 . YDR144C 38 SNEVYVK|MN 0.070 . YDR144C 43 VKMNFQK|KY 0.083 . YDR144C 44 KMNFQKK|YG 0.159 . YDR144C 57 NALDDTK|GR 0.055 . YDR144C 59 LDDTKGR|TR 0.073 . YDR144C 61 DTKGRTR|LM 0.070 . YDR144C 65 RTRLMTR|DD 0.121 . YDR144C 93 IGTPPQK|VT 0.058 . YDR144C 118 NPYCSTK|KK 0.077 . YDR144C 119 PYCSTKK|KD 0.080 . YDR144C 120 YCSTKKK|DT 0.209 . YDR144C 128 TTGSSFK|QV 0.081 . YDR144C 132 SFKQVNK|DA 0.083 . YDR144C 183 GTFNTSK|SS 0.071 . YDR144C 259 SLSSVQK|SY 0.094 . YDR144C 271 NFPMVLK|NS 0.066 . YDR144C 277 KNSGVIK|ST 0.130 . YDR144C 291 ANDSDSK|HG 0.057 . YDR144C 304 GAVDHGK|YA 0.096 . YDR144C 321 INTLQHR|GY 0.090 . YDR144C 324 LQHRGYK|DP 0.186 . YDR144C 340 QGLGTSK|GD 0.058 . YDR144C 343 GTSKGDK|ED 0.060 . YDR144C 354 TTLTTTK|IP 0.054 . YDR144C 374 MPTELVK|ML 0.069 . YDR144C 397 YIMDCIK|EM 0.059 . YDR144C 428 QLVTDSR|SN 0.119 . YDR144C 491 AVPSALK|AP 0.059 . YDR144C 537 TSSSSSK|GQ 0.091 . YDR144C 540 SSSKGQK|TQ 0.065 . YDR144C 552 TALSISK|ST 0.076 . YDR144C 572 TSSSSTR|KE 0.119 . YDR144C 573 SSSSTRK|EN 0.134 . YDR144C 587 NPPFFAR|FI 0.232 . ____________________________^_________________

Fasta :-
>YDR144C ATGAAATTATCTGTCCTCACATTTGTCGTAGATGCATTACTTGTCTGCAGCTCAATAGTA GATGCCGGTGTTACAGATTTTCCATCCTTACCAAGTAATGAAGTCTATGTCAAAATGAAT TTTCAGAAGAAATACGGCAGTTCATTTGAAAACGCTTTGGATGATACAAAAGGTAGAACG CGTTTGATGACAAGAGATGATGATTACGAGCTGGTGGAACTGACTAATCAAAACAGTTTT TATTCGGTGGAATTAGATATTGGCACCCCTCCTCAAAAAGTTACTGTGCTTGTCGACACT GGTTCTTCTGATCTATGGGTCACGGGTTCAGACAACCCATACTGTTCCACTAAAAAGAAG GATACCACTGGCTCATCCTTTAAACAAGTAAACAAGGATGCTTTGGCTAGCGTGGTTGAG AGTGTGTTTACTGAAATTAGCTACGACACCACTATAGTTACCAGCGAAGCCACTGCTACT TTTGATAGTACAGCTTCTACATCACAGTTAATTGACTGCGCTACATACGGGACATTTAAT ACCTCTAAGTCGTCTACATTCAACTCCAATAATACAGAATTTTCGATCGCCTATGGTGAT ACGACTTTTGCATCTGGTACCTGGGGCCATGATCAATTGAGCTTGAACGATTTGAACATT ACGGGTTTATCATTTGCTGTAGCAAACGAAACAAACTCAACAGTTGGTGTCTTGGGTATT GGTTTGCCTGGCTTGGAGTCAACTTATTCTGGTGTTTCTCTCAGCTCTGTACAAAAAAGC TACACTTACAATAACTTTCCGATGGTGCTAAAGAATTCGGGTGTAATAAAATCAACAGCT TATTCTTTATTCGCAAATGATTCTGATTCGAAACATGGTACCATTTTGTTTGGCGCTGTG GATCATGGAAAATATGCGGGCGACCTATACACAATTCCCATCATTAATACTTTGCAGCAT CGCGGCTACAAGGATCCAATTCAATTCCAAGTCACTTTACAAGGATTAGGTACGTCGAAA GGGGATAAAGAAGACAATCTGACAACCCTAACCACTACAAAGATCCCAGTCCTGCTAGAT TCAGGTACGACCATATCGTATATGCCAACTGAGCTGGTAAAAATGCTTGCCGACCAGGTC GGAGCTACTTACTCTTCTGCATATGGTTACTACATAATGGATTGTATCAAAGAGATGGAA GAAGAGAGTAGCATCATCTTTGATTTTGGTGGATTCTATCTTTCTAATTGGTTAAGCGAT TTTCAGCTAGTCACAGATAGTCGTTCAAACATTTGTATACTAGGTATTGCACCGCAGTCA GATCCGACCATTATTTTGGGTGATAACTTCTTAGCTAATACTTACGTGGTATATGATCTG GACAATATGGAGATATCAATGGCTCAGGCTAACTTCAGCGACGACGGTGAATACATTGAG ATTATAGAGAGCGCGGTTCCAAGTGCTCTTAAAGCACCTGGTTACTCAAGCACTTGGTCT ACATATGAAAGTATTGTCTCCGGCGGCAACATGTTTTCCACGGCAGCTAACTCCAGTATA TCGTACTTTGCTTCCACGTCTCATTCGGCAACAAGTTCTTCCAGCTCCAAAGGCCAAAAA ACCCAAACAAGTACGACAGCTCTCTCTATTTCAAAATCTACCTCAAGTACTTCCTCAACA GGAATGTTATCTCCCACCTCAAGTTCATCTACGAGAAAAGAAAACGGAGGACACAATCTG AATCCTCCATTTTTCGCCAGGTTCATTACAGCTATTTTTCATCACATTTGA
Download Fasta

Fasta :-

MKLSVLTFVVDALLVCSSIVDAGVTDFPSLPSNEVYVKMNFQKKYGSSFENALDDTKGRT RLMTRDDDYELVELTNQNSFYSVELDIGTPPQKVTVLVDTGSSDLWVTGSDNPYCSTKKK DTTGSSFKQVNKDALASVVESVFTEISYDTTIVTSEATATFDSTASTSQLIDCATYGTFN TSKSSTFNSNNTEFSIAYGDTTFASGTWGHDQLSLNDLNITGLSFAVANETNSTVGVLGI GLPGLESTYSGVSLSSVQKSYTYNNFPMVLKNSGVIKSTAYSLFANDSDSKHGTILFGAV DHGKYAGDLYTIPIINTLQHRGYKDPIQFQVTLQGLGTSKGDKEDNLTTLTTTKIPVLLD SGTTISYMPTELVKMLADQVGATYSSAYGYYIMDCIKEMEEESSIIFDFGGFYLSNWLSD FQLVTDSRSNICILGIAPQSDPTIILGDNFLANTYVVYDLDNMEISMAQANFSDDGEYIE IIESAVPSALKAPGYSSTWSTYESIVSGGNMFSTAANSSISYFASTSHSATSSSSSKGQK TQTSTTALSISKSTSSTSSTGMLSPTSSSSTRKENGGHNLNPPFFARFITAIFHHI

Pepsin-like

title: catalytic residue
coordinates: D99,D360

No Results

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YDR144C	567 S	LSPTSSSST	0.992	unsp	YDR144C	567 S	LSPTSSSST	0.992	unsp	YDR144C	567 S	LSPTSSSST	0.992	unsp	YDR144C	532 S	HSATSSSSS	0.992	unsp	YDR144C	535 S	TSSSSSKGQ	0.996	unsp

YDR144C | aspartyl protease

ID's

UniProt_ID: P53379

GEO Functions

Computed_GO_Component_IDs: GO:0031225 GO:0016020 GO:0005886

Computed_GO_Components: anchored component of membrane membrane plasma membrane

Computed_GO_Function_IDs: GO:0004190 GO:0016787 GO:0008233

Computed_GO_Functions: aspartic-type endopeptidase activity hydrolase activity peptidase activity

Computed_GO_Process_IDs: GO:0006508

Computed_GO_Processes: proteolysis

Curated_GO_Component_IDs: GO:0031362 GO:0005576 GO:0009277 GO:0000324

Curated_GO_Components: anchored component of external side of plasma membrane extracellular region fungal-type cell wall fungal-type vacuole

Curated_GO_Function_IDs: GO:0004190

Curated_GO_Functions: aspartic-type endopeptidase activity

Curated_GO_Processes: fungal-type cell wall organization protein catabolic process proteolysis signal transduction involved in filamentous growth

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Pepsin-like

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YDR144C

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India