YHR134W | metalloendopeptidase WSS1

UniProt_ID: P38838

Computed_GO_Component_IDs: GO:0005634
Computed_GO_Components: nucleus
Computed_GO_Function_IDs: GO:0016787 GO:0046872 GO:0008237 GO:0008233
Computed_GO_Functions: hydrolase activity metal ion binding metallopeptidase activity peptidase activity
Computed_GO_Process_IDs: GO:0006974 GO:0006508
Computed_GO_Processes: cellular response to DNA damage stimulus proteolysis
Curated_GO_Component_IDs: GO:0000324 GO:0005635
Curated_GO_Components: fungal-type vacuole nuclear envelope
Curated_GO_Function_IDs: GO:0032183 GO:0061665 GO:0070140 GO:0004222 GO:0008237
Curated_GO_Functions: SUMO binding SUMO ligase activity SUMO-specific isopeptidase activity metalloendopeptidase activity metallopeptidase activity
Curated_GO_Processes: cellular response to DNA damage stimulus protein autosumoylation protein desumoylation protein sumoylation replication-born double-strand break repair via sister chromatid exchange response to UV-B response to UV-C translesion synthesis

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YHR134W	OTHER	0.999459	0.000022	0.000519

No Results

Fasta :-
>YHR134W MKTEGIKSPSAKYHDMAGSQRIPHKNPHIQKVAVLQSKPNKEDALNLIKEIAHKVSYLMK ENHFKVTNLVEFYPRDQRLLGMNVNHGSKIMLRLRCSTDEFQFLPMECIMGTMLHELTHN LFGPHDKKFYNKLDELIGRQWVIEQRGLYDTFLGNGQRLGGRANLRSNRYPMTGISTNTG IVRKRGKGVKLGSLHPEGISSIDRGNSPRELAAFAAERRYRDDRWCGETKNNKDQIISDN ISSSLEVVILDDDDEVLPGDTLIEVIDLT
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YHR134W.fa Sequence name : YHR134W Sequence length : 269 VALUES OF COMPUTED PARAMETERS Coef20 : 3.113 CoefTot : -0.113 ChDiff : 4 ZoneTo : 3 KR : 1 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 0.565 0.782 -0.191 0.419 MesoH : -1.228 -0.105 -0.633 0.056 MuHd_075 : 10.519 11.929 3.609 2.850 MuHd_095 : 19.291 8.326 4.583 3.540 MuHd_100 : 16.398 8.027 4.275 2.583 MuHd_105 : 14.992 7.584 4.213 2.019 Hmax_075 : 0.583 4.083 -1.036 2.403 Hmax_095 : 2.450 2.538 -1.893 2.328 Hmax_100 : -0.600 1.000 -2.299 2.020 Hmax_105 : 10.733 6.300 0.917 3.138 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9257 0.0743 DFMC : 0.9323 0.0677

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 269 YHR134W MKTEGIKSPSAKYHDMAGSQRIPHKNPHIQKVAVLQSKPNKEDALNLIKEIAHKVSYLMKENHFKVTNLVEFYPRDQRLL 80 GMNVNHGSKIMLRLRCSTDEFQFLPMECIMGTMLHELTHNLFGPHDKKFYNKLDELIGRQWVIEQRGLYDTFLGNGQRLG 160 GRANLRSNRYPMTGISTNTGIVRKRGKGVKLGSLHPEGISSIDRGNSPRELAAFAAERRYRDDRWCGETKNNKDQIISDN 240 ISSSLEVVILDDDDEVLPGDTLIEVIDLT 320 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ............................. 320 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ YHR134W 2 -----MK|TE 0.069 . YHR134W 7 MKTEGIK|SP 0.083 . YHR134W 12 IKSPSAK|YH 0.130 . YHR134W 21 DMAGSQR|IP 0.100 . YHR134W 25 SQRIPHK|NP 0.077 . YHR134W 31 KNPHIQK|VA 0.059 . YHR134W 38 VAVLQSK|PN 0.058 . YHR134W 41 LQSKPNK|ED 0.066 . YHR134W 49 DALNLIK|EI 0.058 . YHR134W 54 IKEIAHK|VS 0.058 . YHR134W 60 KVSYLMK|EN 0.074 . YHR134W 65 MKENHFK|VT 0.077 . YHR134W 75 LVEFYPR|DQ 0.091 . YHR134W 78 FYPRDQR|LL 0.192 . YHR134W 89 NVNHGSK|IM 0.055 . YHR134W 93 GSKIMLR|LR 0.071 . YHR134W 95 KIMLRLR|CS 0.091 . YHR134W 127 LFGPHDK|KF 0.076 . YHR134W 128 FGPHDKK|FY 0.092 . YHR134W 132 DKKFYNK|LD 0.074 . YHR134W 139 LDELIGR|QW 0.095 . YHR134W 146 QWVIEQR|GL 0.096 . YHR134W 158 FLGNGQR|LG 0.076 . YHR134W 162 GQRLGGR|AN 0.080 . YHR134W 166 GGRANLR|SN 0.116 . YHR134W 169 ANLRSNR|YP 0.324 . YHR134W 183 TNTGIVR|KR 0.106 . YHR134W 184 NTGIVRK|RG 0.073 . YHR134W 185 TGIVRKR|GK 0.346 . YHR134W 187 IVRKRGK|GV 0.087 . YHR134W 190 KRGKGVK|LG 0.066 . YHR134W 204 GISSIDR|GN 0.127 . YHR134W 209 DRGNSPR|EL 0.106 . YHR134W 218 AAFAAER|RY 0.085 . YHR134W 219 AFAAERR|YR 0.134 . YHR134W 221 AAERRYR|DD 0.364 . YHR134W 224 RRYRDDR|WC 0.343 . YHR134W 230 RWCGETK|NN 0.067 . YHR134W 233 GETKNNK|DQ 0.065 . ____________________________^_________________

Fasta :-
>YHR134W ATGAAGACAGAAGGAATAAAAAGCCCATCGGCAAAATACCATGATATGGCGGGCTCCCAG AGAATCCCTCACAAGAACCCGCACATTCAAAAAGTGGCTGTTTTGCAAAGTAAGCCCAAT AAGGAAGATGCGCTAAATTTAATAAAGGAAATCGCACATAAAGTTTCCTATCTAATGAAG GAAAATCACTTCAAAGTGACCAACTTGGTGGAGTTTTACCCACGTGATCAAAGACTCCTG GGAATGAACGTCAACCATGGATCTAAGATAATGTTACGGTTAAGATGCTCCACGGATGAG TTCCAATTTTTACCCATGGAGTGTATAATGGGCACCATGCTGCACGAATTAACTCACAAT TTATTCGGTCCACACGACAAAAAGTTCTACAATAAGCTAGATGAGTTGATTGGAAGGCAA TGGGTTATTGAACAAAGAGGTTTGTACGACACATTTTTGGGGAACGGTCAACGTCTCGGT GGAAGAGCAAACTTACGTTCAAATAGATATCCTATGACAGGAATAAGTACTAACACAGGG ATAGTGAGAAAAAGGGGCAAAGGTGTGAAGTTAGGGAGTTTGCATCCAGAGGGTATATCA TCTATAGATAGAGGTAATTCCCCGAGAGAGTTGGCGGCTTTTGCAGCCGAAAGGAGATAT AGAGATGATCGCTGGTGCGGAGAGACGAAGAATAACAAAGATCAAATAATAAGTGATAAT ATTAGCAGCTCCTTAGAAGTTGTAATCCTTGATGATGATGACGAGGTACTCCCGGGAGAT ACTCTTATCGAAGTTATTGATCTCACTTAA
Download Fasta

Fasta :-

MKTEGIKSPSAKYHDMAGSQRIPHKNPHIQKVAVLQSKPNKEDALNLIKEIAHKVSYLMK ENHFKVTNLVEFYPRDQRLLGMNVNHGSKIMLRLRCSTDEFQFLPMECIMGTMLHELTHN LFGPHDKKFYNKLDELIGRQWVIEQRGLYDTFLGNGQRLGGRANLRSNRYPMTGISTNTG IVRKRGKGVKLGSLHPEGISSIDRGNSPRELAAFAAERRYRDDRWCGETKNNKDQIISDN ISSSLEVVILDDDDEVLPGDTLIEVIDLT

No Results

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	YHR134W	T	3	0.537	0.078	YHR134W	T	269	0.506	0.032

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	YHR134W	T	3	0.537	0.078	YHR134W	T	269	0.506	0.032

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YHR134W	10 S	IKSPSAKYH	0.99	unsp	YHR134W	207 S	DRGNSPREL	0.998	unsp

YHR134W | metalloendopeptidase WSS1

ID's

UniProt_ID: P38838

GEO Functions

Computed_GO_Component_IDs: GO:0005634

Computed_GO_Components: nucleus

Computed_GO_Function_IDs: GO:0016787 GO:0046872 GO:0008237 GO:0008233

Computed_GO_Functions: hydrolase activity metal ion binding metallopeptidase activity peptidase activity

Computed_GO_Process_IDs: GO:0006974 GO:0006508

Computed_GO_Processes: cellular response to DNA damage stimulus proteolysis

Curated_GO_Component_IDs: GO:0000324 GO:0005635

Curated_GO_Components: fungal-type vacuole nuclear envelope

Curated_GO_Function_IDs: GO:0032183 GO:0061665 GO:0070140 GO:0004222 GO:0008237

Curated_GO_Functions: SUMO binding SUMO ligase activity SUMO-specific isopeptidase activity metalloendopeptidase activity metallopeptidase activity

Curated_GO_Processes: cellular response to DNA damage stimulus protein autosumoylation protein desumoylation protein sumoylation replication-born double-strand break repair via sister chromatid exchange response to UV-B response to UV-C translesion synthesis

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YHR134W

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India