YNL238W | kexin KEX2

UniProt_ID: P13134

Computed_GO_Component_IDs: GO:0005794 GO:0016021 GO:0016020
Computed_GO_Components: Golgi apparatus integral component of membrane membrane
Computed_GO_Function_IDs: GO:0016787 GO:0046872 GO:0008233 GO:0004252 GO:0008236
Computed_GO_Functions: hydrolase activity metal ion binding peptidase activity serine-type endopeptidase activity serine-type peptidase activity
Computed_GO_Process_IDs: GO:0006508
Computed_GO_Processes: proteolysis
Curated_GO_Component_IDs: GO:0000324 GO:0030173 GO:0016020 GO:0005802
Curated_GO_Components: fungal-type vacuole integral component of Golgi membrane membrane trans-Golgi network
Curated_GO_Function_IDs: GO:0005515 GO:0004252
Curated_GO_Functions: protein binding serine-type endopeptidase activity
Curated_GO_Processes: peptide pheromone maturation protein processing

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YNL238W	SP	0.016146	0.979768	0.004086	CS pos: 23-24. VSS-QQ. Pr: 0.6207

No Results

Fasta :-
>YNL238W MKVRKYITLCFWWAFSTSALVSSQQIPLKDHTSRQYFAVESNETLSRLEEMHPNWKYEHD VRGLPNHYVFSKELLKLGKRSSLEELQGDNNDHILSVHDLFPRNDLFKRLPVPAPPMDSS LLPVKEAEDKLSINDPLFERQWHLVNPSFPGSDINVLDLWYNNITGAGVVAAIVDDGLDY ENEDLKDNFCAEGSWDFNDNTNLPKPRLSDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKI SGIRILSGDITTEDEAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEG RDSKGAIYVFASGNGGTRGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTY SSGSGEYIHSSDINGRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVG LEKNADGDWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTN STEETLESVITISEKSLQDANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVR PRDVSSEGFKDWTFMSVAHWGENGVGDWKIKVKTTENGHRIDFHSWRLKLFGESIDSSKT ETFVFGNDKEEVEPAATESTVSQYSASSTSISISATSTSSISIGVETSAIPQTTTASTDP DSDPNTPKKLSSPRQAMHYFLTIFLIGATFLVLYFMFFMKSRRRIRRSRAETYEFDIIDT DSEYDSTLDNGTSGITEPEEVEDFDFDLSDEDHLASLSSSENGDAEHTIDSVLTNENPFS DPIKQKFPNDANAESASNKLQELQPDVPPSSGRS
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YNL238W.fa Sequence name : YNL238W Sequence length : 814 VALUES OF COMPUTED PARAMETERS Coef20 : 4.960 CoefTot : 0.172 ChDiff : -46 ZoneTo : 29 KR : 4 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 2.682 2.459 0.406 0.929 MesoH : 0.219 0.269 -0.228 0.235 MuHd_075 : 19.596 13.212 4.675 4.968 MuHd_095 : 17.630 18.250 7.539 4.643 MuHd_100 : 15.049 14.796 7.745 3.260 MuHd_105 : 14.176 12.662 7.443 3.975 Hmax_075 : 15.800 14.262 3.499 6.080 Hmax_095 : 16.538 17.150 4.171 5.469 Hmax_100 : 14.800 14.300 3.990 4.430 Hmax_105 : 12.000 18.783 3.275 4.810 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.8800 0.1200 DFMC : 0.7747 0.2253

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 814 YNL238W MKVRKYITLCFWWAFSTSALVSSQQIPLKDHTSRQYFAVESNETLSRLEEMHPNWKYEHDVRGLPNHYVFSKELLKLGKR 80 SSLEELQGDNNDHILSVHDLFPRNDLFKRLPVPAPPMDSSLLPVKEAEDKLSINDPLFERQWHLVNPSFPGSDINVLDLW 160 YNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGSWDFNDNTNLPKPRLSDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKI 240 SGIRILSGDITTEDEAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVFASGNGGTRGD 320 NCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTYSSGSGEYIHSSDINGRCSNSHGGTSAAAPLAAGVYTLLLE 400 ANPNLTWRDVQYLSILSAVGLEKNADGDWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTN 480 STEETLESVITISEKSLQDANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVRPRDVSSEGFKDWTFMSVAHW 560 GENGVGDWKIKVKTTENGHRIDFHSWRLKLFGESIDSSKTETFVFGNDKEEVEPAATESTVSQYSASSTSISISATSTSS 640 ISIGVETSAIPQTTTASTDPDSDPNTPKKLSSPRQAMHYFLTIFLIGATFLVLYFMFFMKSRRRIRRSRAETYEFDIIDT 720 DSEYDSTLDNGTSGITEPEEVEDFDFDLSDEDHLASLSSSENGDAEHTIDSVLTNENPFSDPIKQKFPNDANAESASNKL 800 QELQPDVPPSSGRS 880 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ................................................................................ 480 ................................................................................ 560 ................................................................................ 640 ..................................................................P............. 720 ................................................................................ 800 .............. 880 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 1 Name Pos Context Score Pred ____________________________v_________________ YNL238W 2 -----MK|VR 0.059 . YNL238W 4 ---MKVR|KY 0.093 . YNL238W 5 --MKVRK|YI 0.113 . YNL238W 29 SQQIPLK|DH 0.069 . YNL238W 34 LKDHTSR|QY 0.139 . YNL238W 47 SNETLSR|LE 0.085 . YNL238W 56 EMHPNWK|YE 0.071 . YNL238W 62 KYEHDVR|GL 0.082 . YNL238W 72 NHYVFSK|EL 0.066 . YNL238W 76 FSKELLK|LG 0.052 . YNL238W 79 ELLKLGK|RS 0.065 . YNL238W 80 LLKLGKR|SS 0.193 . YNL238W 103 VHDLFPR|ND 0.068 . YNL238W 108 PRNDLFK|RL 0.063 . YNL238W 109 RNDLFKR|LP 0.148 . YNL238W 125 SSLLPVK|EA 0.078 . YNL238W 130 VKEAEDK|LS 0.057 . YNL238W 140 NDPLFER|QW 0.088 . YNL238W 186 YENEDLK|DN 0.077 . YNL238W 205 DNTNLPK|PR 0.057 . YNL238W 207 TNLPKPR|LS 0.129 . YNL238W 216 DDYHGTR|CA 0.103 . YNL238W 224 AGEIAAK|KG 0.056 . YNL238W 225 GEIAAKK|GN 0.100 . YNL238W 239 GVGYNAK|IS 0.071 . YNL238W 244 AKISGIR|IL 0.104 . YNL238W 280 GPADDGR|HL 0.101 . YNL238W 290 GPSDLVK|KA 0.082 . YNL238W 291 PSDLVKK|AL 0.117 . YNL238W 295 VKKALVK|GV 0.092 . YNL238W 301 KGVTEGR|DS 0.107 . YNL238W 304 TEGRDSK|GA 0.194 . YNL238W 318 SGNGGTR|GD 0.089 . YNL238W 342 IGAIDHK|DL 0.075 . YNL238W 376 SSDINGR|CS 0.100 . YNL238W 408 NPNLTWR|DV 0.164 . YNL238W 423 SAVGLEK|NA 0.067 . YNL238W 430 NADGDWR|DS 0.102 . YNL238W 436 RDSAMGK|KY 0.084 . YNL238W 437 DSAMGKK|YS 0.133 . YNL238W 441 GKKYSHR|YG 0.135 . YNL238W 446 HRYGFGK|ID 0.079 . YNL238W 451 GKIDAHK|LI 0.073 . YNL238W 457 KLIEMSK|TW 0.071 . YNL238W 495 VITISEK|SL 0.079 . YNL238W 503 LQDANFK|RI 0.071 . YNL238W 504 QDANFKR|IE 0.191 . YNL238W 519 DIDTEIR|GT 0.082 . YNL238W 540 SNLGVVR|PR 0.085 . YNL238W 542 LGVVRPR|DV 0.194 . YNL238W 550 VSSEGFK|DW 0.074 . YNL238W 569 NGVGDWK|IK 0.054 . YNL238W 571 VGDWKIK|VK 0.063 . YNL238W 573 DWKIKVK|TT 0.075 . YNL238W 580 TTENGHR|ID 0.086 . YNL238W 587 IDFHSWR|LK 0.095 . YNL238W 589 FHSWRLK|LF 0.085 . YNL238W 599 ESIDSSK|TE 0.059 . YNL238W 609 FVFGNDK|EE 0.052 . YNL238W 668 SDPNTPK|KL 0.071 . YNL238W 669 DPNTPKK|LS 0.148 . YNL238W 674 KKLSSPR|QA 0.139 . YNL238W 700 YFMFFMK|SR 0.084 . YNL238W 702 MFFMKSR|RR 0.072 . YNL238W 703 FFMKSRR|RI 0.163 . YNL238W 704 FMKSRRR|IR 0.091 . YNL238W 706 KSRRRIR|RS 0.311 . YNL238W 707 SRRRIRR|SR 0.670 *ProP* YNL238W 709 RRIRRSR|AE 0.328 . YNL238W 784 PFSDPIK|QK 0.074 . YNL238W 786 SDPIKQK|FP 0.084 . YNL238W 799 AESASNK|LQ 0.074 . YNL238W 813 VPPSSGR|S- 0.157 . ____________________________^_________________

Fasta :-
>YNL238W ATGAAAGTGAGGAAATATATTACTTTATGCTTTTGGTGGGCCTTTTCAACATCCGCTCTT GTATCATCACAACAAATTCCATTGAAGGACCATACGTCACGACAGTATTTTGCTGTAGAA AGCAATGAAACATTATCCCGCTTGGAGGAAATGCATCCAAATTGGAAATATGAACATGAT GTTCGAGGGCTACCAAACCATTATGTTTTTTCAAAAGAGTTGCTAAAATTGGGCAAAAGA TCATCATTAGAAGAGTTACAGGGGGATAACAACGACCACATATTATCTGTCCATGATTTA TTCCCGCGTAACGACCTATTTAAGAGACTACCGGTGCCTGCTCCACCAATGGACTCAAGC TTGTTACCGGTAAAAGAAGCTGAGGATAAACTCAGCATAAATGATCCGCTTTTTGAGAGG CAGTGGCACTTGGTCAATCCAAGTTTTCCTGGCAGTGATATAAATGTTCTTGATCTGTGG TACAATAATATTACAGGCGCAGGGGTCGTGGCTGCCATTGTTGATGATGGCCTTGACTAC GAAAATGAAGACTTGAAGGATAATTTTTGCGCTGAAGGTTCTTGGGATTTCAACGACAAT ACCAATTTACCTAAACCAAGATTATCTGATGACTACCATGGTACGAGATGTGCAGGTGAA ATAGCTGCCAAAAAAGGTAACAATTTTTGCGGTGTCGGGGTAGGTTACAACGCTAAAATC TCAGGCATAAGAATCTTATCCGGTGATATCACTACGGAAGATGAAGCTGCGTCCTTGATT TATGGTCTAGACGTAAACGATATATATTCATGCTCATGGGGTCCCGCTGATGACGGAAGA CATTTACAAGGCCCTAGTGACCTGGTGAAAAAGGCTTTAGTAAAAGGTGTTACTGAGGGA AGAGATTCCAAAGGAGCGATTTACGTTTTTGCCAGTGGAAATGGTGGAACTCGTGGTGAT AATTGCAATTACGACGGCTATACTAATTCCATATATTCTATTACTATTGGGGCTATTGAT CACAAAGATCTACATCCTCCTTATTCCGAAGGTTGTTCCGCCGTCATGGCAGTCACGTAT TCTTCAGGTTCAGGCGAATATATTCATTCGAGTGATATCAACGGCAGATGCAGTAATAGC CACGGTGGAACGTCTGCGGCTGCTCCATTAGCTGCCGGTGTTTACACTTTGTTACTAGAA GCCAACCCAAACCTAACTTGGAGAGACGTACAGTATTTATCAATCTTGTCTGCGGTAGGG TTAGAAAAGAACGCTGACGGAGATTGGAGAGATAGCGCCATGGGGAAGAAATACTCTCAT CGCTATGGCTTTGGTAAAATCGATGCCCATAAGTTAATTGAAATGTCCAAGACCTGGGAG AATGTTAACGCACAAACCTGGTTTTACCTGCCAACATTGTATGTTTCCCAGTCCACAAAC TCCACGGAAGAGACATTAGAATCCGTCATAACCATATCAGAAAAAAGTCTTCAAGATGCT AACTTCAAGAGAATTGAGCACGTCACGGTAACTGTAGATATTGATACAGAAATTAGGGGA ACTACGACTGTCGATTTAATATCACCAGCGGGGATAATTTCAAACCTTGGCGTTGTAAGA CCAAGAGATGTTTCATCAGAGGGATTCAAAGACTGGACATTCATGTCTGTAGCACATTGG GGTGAGAACGGCGTAGGTGATTGGAAAATCAAGGTTAAGACAACAGAAAATGGACACAGG ATTGACTTCCACAGTTGGAGGCTGAAGCTCTTTGGGGAATCCATTGATTCATCTAAAACA GAAACTTTCGTCTTTGGAAACGATAAAGAGGAGGTTGAACCAGCTGCTACAGAAAGTACC GTATCACAATATTCTGCCAGTTCAACTTCTATTTCCATCAGCGCTACTTCTACATCTTCT ATCTCAATTGGTGTGGAAACGTCGGCCATTCCCCAAACGACTACTGCGAGTACCGATCCT GATTCTGATCCAAACACTCCTAAAAAACTTTCCTCTCCTAGGCAAGCCATGCATTATTTT TTAACAATATTTTTGATTGGCGCCACATTTTTGGTGTTATACTTCATGTTTTTTATGAAA TCAAGGAGAAGGATCAGAAGGTCAAGAGCGGAAACGTATGAATTCGATATCATTGATACA GACTCTGAGTACGATTCTACTTTGGACAATGGAACTTCCGGAATTACTGAGCCCGAAGAG GTTGAGGACTTCGATTTTGATTTGTCCGATGAAGACCATCTTGCAAGTTTGTCTTCATCA GAAAACGGTGATGCTGAACATACAATTGATAGTGTACTAACAAACGAAAATCCATTTAGT GACCCTATAAAGCAAAAGTTCCCAAATGACGCCAACGCAGAATCTGCTTCCAATAAATTA CAAGAATTACAGCCTGATGTTCCTCCATCTTCCGGACGATCGTGA
Download Fasta

Fasta :-

MKVRKYITLCFWWAFSTSALVSSQQIPLKDHTSRQYFAVESNETLSRLEEMHPNWKYEHD VRGLPNHYVFSKELLKLGKRSSLEELQGDNNDHILSVHDLFPRNDLFKRLPVPAPPMDSS LLPVKEAEDKLSINDPLFERQWHLVNPSFPGSDINVLDLWYNNITGAGVVAAIVDDGLDY ENEDLKDNFCAEGSWDFNDNTNLPKPRLSDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKI SGIRILSGDITTEDEAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEG RDSKGAIYVFASGNGGTRGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTY SSGSGEYIHSSDINGRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVG LEKNADGDWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTN STEETLESVITISEKSLQDANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVR PRDVSSEGFKDWTFMSVAHWGENGVGDWKIKVKTTENGHRIDFHSWRLKLFGESIDSSKT ETFVFGNDKEEVEPAATESTVSQYSASSTSISISATSTSSISIGVETSAIPQTTTASTDP DSDPNTPKKLSSPRQAMHYFLTIFLIGATFLVLYFMFFMKSRRRIRRSRAETYEFDIIDT DSEYDSTLDNGTSGITEPEEVEDFDFDLSDEDHLASLSSSENGDAEHTIDSVLTNENPFS DPIKQKFPNDANAESASNKLQELQPDVPPSSGRS

Subtilases

title: active site
coordinates: D175,D176,D210,H213,E255,W273,Q283,N314,D325,S385

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	YNL238W	S	627	0.520	0.027	YNL238W	S	625	0.505	0.044

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	YNL238W	S	627	0.520	0.027	YNL238W	S	625	0.505	0.044

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YNL238W	481 S	QSTNSTEET	0.997	unsp	YNL238W	481 S	QSTNSTEET	0.997	unsp	YNL238W	481 S	QSTNSTEET	0.997	unsp	YNL238W	545 S	PRDVSSEGF	0.996	unsp	YNL238W	598 S	SIDSSKTET	0.995	unsp	YNL238W	662 S	TDPDSDPNT	0.991	unsp	YNL238W	672 S	KKLSSPRQA	0.993	unsp	YNL238W	708 S	RIRRSRAET	0.997	unsp	YNL238W	722 S	IDTDSEYDS	0.996	unsp	YNL238W	726 S	SEYDSTLDN	0.993	unsp	YNL238W	749 S	DFDLSDEDH	0.997	unsp	YNL238W	82 S	GKRSSLEEL	0.996	unsp	YNL238W	303 S	EGRDSKGAI	0.996	unsp

YNL238W | kexin KEX2

ID's

UniProt_ID: P13134

GEO Functions

Computed_GO_Component_IDs: GO:0005794 GO:0016021 GO:0016020

Computed_GO_Components: Golgi apparatus integral component of membrane membrane

Computed_GO_Function_IDs: GO:0016787 GO:0046872 GO:0008233 GO:0004252 GO:0008236

Computed_GO_Functions: hydrolase activity metal ion binding peptidase activity serine-type endopeptidase activity serine-type peptidase activity

Computed_GO_Process_IDs: GO:0006508

Computed_GO_Processes: proteolysis

Curated_GO_Component_IDs: GO:0000324 GO:0030173 GO:0016020 GO:0005802

Curated_GO_Components: fungal-type vacuole integral component of Golgi membrane membrane trans-Golgi network

Curated_GO_Function_IDs: GO:0005515 GO:0004252

Curated_GO_Functions: protein binding serine-type endopeptidase activity

Curated_GO_Processes: peptide pheromone maturation protein processing

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Subtilases

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YNL238W

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India