WNT_SIGNALING_PATHWAY

Differential Network Properties
Rewiring Score: 3.956 Mean Expression: 30.359
Gene count: 69 Rewired gene count: 50
Disease Potential: 0.080 Pathway centrality: 0.231
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Gene Symbol Rewiring Score (local) Rewiring Score (Global) Degree Clustering coefficient Betweeness Page Rank Closeness Overall Global centrality
WNT6 0.000 19.775 55 0.077 0.011 0.008 0.176 0.272
PPP2CB 0.000 144.226 49 0.505 0.072 0.042 0.298 0.917
WNT16 36.235 1174.401 51 0.537 0.423 0.261 0.533 1.753
WNT4 36.742 845.608 55 0.503 0.330 0.196 0.515 1.543
PRKACA 9.415 366.991 48 0.304 0.174 0.107 0.596 1.181
FZD9 25.308 1762.691 41 0.330 0.495 0.428 0.779 2.032
PPP2R5D 3.910 50.563 48 0.148 0.024 0.031 0.166 0.369
WNT3 14.406 519.209 57 0.438 0.225 0.124 0.377 1.163
WNT5B 61.256 775.846 60 0.239 0.345 0.194 0.836 1.614
FZD3 4.036 111.859 54 0.139 0.056 0.046 0.415 0.656
PPP3CC 0.000 319.651 45 0.215 0.145 0.137 0.538 1.035
DAAM1 64.091 1367.137 50 0.476 0.476 0.309 0.612 1.873
SFRP5 0.000 45.254 60 0.140 0.025 0.014 0.228 0.407
WNT7B 19.521 532.882 53 0.253 0.221 0.165 0.573 1.213
PLCB3 0.000 26.295 59 0.143 0.013 0.014 0.064 0.234
FRAT2 8.483 578.156 58 0.143 0.247 0.221 0.620 1.231
CREBBP 32.792 497.217 51 0.416 0.205 0.126 0.580 1.327
MMP7 89.003 1874.931 52 0.458 0.602 0.424 0.552 2.036
CCND3 29.502 2454.489 44 0.405 0.699 0.584 0.514 2.201
NFATC3 0.000 25.150 60 0.275 0.014 0.034 0.171 0.494
PPP3CA 69.337 1182.022 51 0.437 0.486 0.276 0.498 1.696
SOX17 49.323 1151.319 50 0.465 0.406 0.269 0.628 1.768
TP53 13.140 731.883 53 0.218 0.308 0.242 0.467 1.234
SKP1 4.733 139.729 42 0.401 0.071 0.058 0.345 0.875
PRKX 8.396 66.174 51 0.290 0.033 0.022 0.298 0.644
PPP2R5B 4.736 75.124 45 0.161 0.037 0.027 0.302 0.527
CHP2 64.894 1856.945 53 0.501 0.564 0.405 0.439 1.909
CHP1 0.000 65.743 50 0.559 0.037 0.016 0.263 0.875
CTNNBIP1 30.946 543.326 60 0.370 0.234 0.129 0.482 1.215
CSNK1A1 63.144 1622.437 49 0.465 0.591 0.371 0.559 1.985
DVL2 26.127 1018.975 48 0.263 0.405 0.306 0.423 1.397
PPARD 3.778 137.951 59 0.157 0.066 0.067 0.337 0.627
PPP2R1B 8.218 215.879 59 0.401 0.106 0.065 0.329 0.900
PSEN1 0.000 14.569 58 0.178 0.009 0.007 0.122 0.315
TCF7L2 55.082 1194.352 47 0.504 0.413 0.279 0.503 1.699
DAAM2 29.685 2140.185 35 0.498 0.588 0.483 0.565 2.135
FZD1 72.878 1259.955 50 0.484 0.473 0.297 0.492 1.746
NFATC1 0.000 34.209 62 0.108 0.019 0.021 0.304 0.452
CSNK1E 4.213 239.161 43 0.261 0.112 0.070 0.526 0.969
TCF7L1 0.000 62.029 55 0.207 0.032 0.028 0.192 0.459
PRKCB 19.769 1269.401 49 0.414 0.413 0.317 0.752 1.895
PPP3CB 0.000 96.095 62 0.076 0.050 0.060 0.379 0.565
PPP2CA 4.733 56.290 51 0.119 0.027 0.029 0.115 0.291
PLCB2 27.323 1419.774 43 0.344 0.488 0.343 0.696 1.871
FZD10 48.994 1424.121 51 0.443 0.470 0.321 0.753 1.987
CAMK2G 108.464 2275.146 55 0.466 0.709 0.503 0.533 2.210
TCF7 3.910 25.367 50 0.044 0.015 0.016 0.154 0.229
DKK2 49.551 1203.674 50 0.571 0.459 0.263 0.539 1.832
FRAT1 9.465 258.213 48 0.556 0.121 0.067 0.497 1.241
CAMK2B 4.002 5.867 62 0.000 0.003 0.010 0.037 0.050
CSNK2A2 20.836 302.059 57 0.399 0.136 0.095 0.376 1.006
MAPK10 0.000 12.249 44 0.286 0.006 0.006 0.011 0.308
SFRP1 32.065 698.008 59 0.113 0.309 0.205 0.729 1.357
NFATC4 0.000 158.148 46 0.401 0.081 0.047 0.339 0.867
DKK1 19.251 845.204 43 0.194 0.329 0.247 0.676 1.445
PPP2R5C 44.184 975.800 47 0.261 0.353 0.282 0.696 1.591
FZD5 3.990 40.856 51 0.169 0.022 0.017 0.272 0.481
FZD4 61.766 1326.908 51 0.476 0.492 0.309 0.573 1.850
TBL1X 32.787 663.640 62 0.383 0.288 0.167 0.573 1.411
FZD8 0.000 26.834 62 0.331 0.015 0.009 0.125 0.479
ROCK2 4.363 91.452 53 0.246 0.047 0.044 0.266 0.604
CXXC4 0.000 36.602 56 0.194 0.020 0.026 0.133 0.372
RAC1 0.000 51.671 57 0.216 0.027 0.015 0.283 0.541
WIF1 68.890 2217.383 49 0.481 0.627 0.485 0.492 2.084
CCND2 54.018 1037.508 50 0.338 0.358 0.274 0.620 1.590
JUN 21.494 197.753 61 0.312 0.094 0.071 0.448 0.925