TIGHT_JUNCTION

Differential Network Properties
Rewiring Score: 0.639 Mean Expression: 27.731
Gene count: 52 Rewired gene count: 37
Disease Potential: 0.011 Pathway centrality: 0.181
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Gene Symbol Rewiring Score (local) Rewiring Score (Global) Degree Clustering coefficient Betweeness Page Rank Closeness Overall Global centrality
PTEN 4.051 79.389 42 0.132 0.043 0.034 0.315 0.525
SPTAN1 17.942 243.047 40 0.183 0.117 0.081 0.546 0.925
AKT2 0.000 33.919 40 0.481 0.018 0.010 0.179 0.688
PARD3 43.470 1151.594 47 0.439 0.421 0.276 0.558 1.694
PPP2R1B 8.551 215.879 44 0.401 0.106 0.065 0.329 0.900
F11R 8.764 170.311 44 0.274 0.080 0.060 0.307 0.720
PRKCH 5.020 122.261 40 0.126 0.058 0.071 0.376 0.632
TJP3 62.326 1428.079 41 0.508 0.525 0.322 0.566 1.921
CLDN1 16.256 319.305 42 0.499 0.144 0.081 0.383 1.108
CLDN4 43.921 667.082 41 0.337 0.270 0.157 0.717 1.481
TJP2 62.899 1429.087 40 0.397 0.476 0.330 0.637 1.841
MYH6 0.000 82.555 36 0.472 0.045 0.019 0.380 0.917
CLDN8 71.901 2059.734 39 0.498 0.591 0.449 0.521 2.058
MYL2 0.000 12.948 34 0.133 0.005 0.022 0.022 0.182
EPB41 0.000 76.622 44 0.319 0.039 0.031 0.183 0.572
MYL5 12.225 144.980 41 0.344 0.064 0.045 0.320 0.772
GNAI3 21.489 211.856 38 0.462 0.100 0.061 0.342 0.964
CSNK2A2 9.102 302.059 41 0.399 0.136 0.095 0.376 1.006
MAGI1 49.922 863.551 46 0.538 0.371 0.188 0.427 1.524
TJP1 52.439 1731.800 33 0.454 0.550 0.412 0.458 1.874
EXOC3 0.000 89.042 41 0.213 0.047 0.033 0.414 0.707
HRAS 8.725 208.219 44 0.110 0.101 0.071 0.509 0.791
CLDN5 57.796 1477.189 43 0.416 0.513 0.352 0.545 1.826
LLGL2 13.272 731.424 46 0.481 0.300 0.184 0.462 1.427
YBX3 56.676 906.883 46 0.486 0.374 0.212 0.412 1.484
MYL9 12.954 692.731 44 0.106 0.330 0.207 0.919 1.562
JAM2 80.901 2580.938 44 0.391 0.740 0.589 0.498 2.218
MYH11 85.541 2347.746 48 0.373 0.690 0.532 0.646 2.241
CLDN7 0.000 99.240 39 0.267 0.050 0.036 0.267 0.621
EPB41L1 8.655 1039.791 46 0.126 0.411 0.301 0.806 1.644
CLDN10 76.968 2722.216 48 0.357 0.817 0.627 0.836 2.638
CASK 9.424 415.586 39 0.440 0.188 0.110 0.386 1.125
CLDN3 0.000 49.599 46 0.508 0.028 0.025 0.276 0.837
RAB13 3.904 309.746 39 0.336 0.151 0.098 0.383 0.968
PPP2R2D 12.659 860.527 37 0.373 0.329 0.215 0.696 1.614
PRKCB 11.013 1269.401 32 0.414 0.413 0.317 0.752 1.895
CLDN18 0.000 71.568 35 0.331 0.039 0.021 0.396 0.788
GNAI1 41.520 1422.644 39 0.439 0.488 0.330 0.778 2.035
MYH14 39.933 1174.724 46 0.459 0.461 0.275 0.646 1.841
PPP2CA 0.000 56.290 39 0.119 0.027 0.029 0.115 0.291
ACTN2 3.904 49.352 32 0.524 0.026 0.015 0.236 0.801
RRAS 4.360 312.425 40 0.205 0.133 0.106 0.573 1.016
CTNNA1 0.000 43.024 44 0.090 0.021 0.029 0.173 0.313
MYL10 0.000 104.242 40 0.098 0.051 0.061 0.367 0.577
JAM3 0.000 97.932 39 0.115 0.052 0.052 0.481 0.699
INADL 50.052 1544.510 42 0.424 0.564 0.353 0.472 1.813
MYH10 12.002 626.808 32 0.435 0.204 0.174 0.448 1.261
CTTN 0.000 26.987 43 0.338 0.015 0.008 0.136 0.497
PPP2CB 4.762 144.226 35 0.505 0.072 0.042 0.298 0.917
LLGL1 0.000 278.874 36 0.282 0.142 0.096 0.471 0.991
MYL12A 5.016 933.258 39 0.537 0.349 0.226 0.520 1.632