ERBB_SIGNALING_PATHWAY

Differential Network Properties
Rewiring Score: 8.443 Mean Expression: 19.218
Gene count: 38 Rewired gene count: 20
Disease Potential: 0.429 Pathway centrality: 0.103
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Gene Symbol Rewiring Score (local) Rewiring Score (Global) Degree Clustering coefficient Betweeness Page Rank Closeness Overall Global centrality
SOS1 0.000 108.936 23 0.300 0.051 0.047 0.218 0.615
NCK1 9.197 488.198 26 0.479 0.211 0.125 0.419 1.234
MAPK10 0.000 12.249 28 0.286 0.006 0.006 0.011 0.308
PAK6 13.054 683.104 30 0.492 0.268 0.161 0.300 1.221
CBLC 16.336 346.707 29 0.466 0.158 0.081 0.356 1.061
NRG2 5.420 271.400 24 0.214 0.125 0.096 0.611 1.046
PIK3R3 0.000 51.513 27 0.153 0.027 0.022 0.264 0.467
RAF1 0.000 226.341 30 0.234 0.103 0.072 0.520 0.929
PAK4 4.754 626.799 26 0.402 0.254 0.160 0.637 1.453
CDKN1B 0.000 248.438 21 0.185 0.115 0.098 0.552 0.951
PAK7 0.000 2.720 28 0.000 0.002 0.012 0.009 0.023
MAP2K4 14.473 783.336 25 0.426 0.349 0.201 0.481 1.458
PIK3CB 0.000 366.681 27 0.216 0.157 0.126 0.620 1.119
EREG 18.733 829.145 24 0.394 0.323 0.193 0.588 1.497
BTC 27.893 1015.253 26 0.560 0.420 0.222 0.492 1.694
PLCG2 10.608 569.406 26 0.349 0.206 0.173 0.477 1.205
TGFA 4.351 280.225 32 0.464 0.137 0.064 0.400 1.065
AREG 4.125 112.498 31 0.139 0.058 0.029 0.285 0.510
JUN 0.000 197.753 27 0.312 0.094 0.071 0.448 0.925
AKT2 0.000 33.919 29 0.481 0.018 0.010 0.179 0.688
ERBB2 20.436 1296.514 32 0.126 0.461 0.397 0.707 1.691
MTOR 3.863 143.933 24 0.385 0.070 0.040 0.332 0.826
STAT5A 8.997 1864.073 27 0.348 0.546 0.454 0.675 2.022
RPS6KB2 0.000 331.008 29 0.133 0.163 0.099 0.596 0.992
STAT5B 0.000 51.470 31 0.222 0.027 0.020 0.229 0.497
EGF 0.000 5.965 28 0.167 0.003 0.002 0.065 0.237
PRKCB 14.323 1269.401 23 0.414 0.413 0.317 0.752 1.895
PIK3R1 4.779 99.582 31 0.222 0.047 0.042 0.159 0.470
ERBB4 0.000 72.991 31 0.532 0.039 0.017 0.255 0.844
PAK3 9.508 664.606 30 0.583 0.319 0.145 0.559 1.606
CAMK2G 31.558 2275.146 25 0.466 0.709 0.503 0.533 2.210
MAPK1 0.000 90.822 24 0.286 0.044 0.031 0.287 0.648
HRAS 0.000 208.219 26 0.110 0.101 0.071 0.509 0.791
EGFR 34.285 2079.304 29 0.454 0.634 0.463 0.637 2.189
ARAF 5.482 1356.493 25 0.240 0.463 0.365 0.657 1.724
MAP2K7 0.000 18.047 26 0.200 0.009 0.010 0.105 0.325
CAMK2B 0.000 5.867 30 0.000 0.003 0.010 0.037 0.050