B_CELL_RECEPTOR_SIGNALING_PATHWAY

Differential Network Properties
Rewiring Score: 1.047 Mean Expression: 8.329
Gene count: 41 Rewired gene count: 32
Disease Potential: 0.233 Pathway centrality: 0.090
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Gene Symbol Rewiring Score (local) Rewiring Score (Global) Degree Clustering coefficient Betweeness Page Rank Closeness Overall Global centrality
GRB2 0.000 208.312 27 0.277 0.081 0.071 0.372 0.801
PTPN6 0.000 265.029 25 0.182 0.113 0.098 0.562 0.954
RASGRP3 1.654 1046.965 32 0.734 0.465 0.369 0.859 2.428
CR2 3.580 509.207 32 0.525 0.214 0.216 0.442 1.397
AKT1 0.000 605.889 32 0.610 0.289 0.215 0.728 1.842
PIK3R2 4.792 572.124 27 0.474 0.248 0.221 0.628 1.571
RAC2 1.800 288.456 26 0.428 0.110 0.116 0.313 0.967
BLNK 4.870 572.605 30 0.340 0.263 0.231 0.733 1.568
IKBKG 0.000 324.228 30 0.336 0.142 0.115 0.506 1.099
PIK3CG 5.888 674.781 33 0.550 0.287 0.270 0.638 1.745
CD79B 8.620 808.414 36 0.465 0.355 0.302 0.734 1.856
CD72 3.395 402.837 35 0.085 0.186 0.177 0.676 1.123
VAV1 3.790 414.375 30 0.538 0.186 0.157 0.546 1.426
CD22 7.551 487.441 29 0.137 0.234 0.191 0.745 1.308
MALT1 1.628 313.200 17 0.306 0.119 0.143 0.423 0.991
PIK3R1 5.677 722.624 33 0.482 0.337 0.275 0.782 1.876
NFATC1 1.559 565.898 36 0.331 0.256 0.224 0.702 1.514
INPP5D 5.589 824.477 24 0.684 0.291 0.340 0.598 1.913
AKT3 1.477 283.127 26 0.160 0.115 0.105 0.487 0.867
SOS1 3.511 296.429 29 0.210 0.129 0.112 0.497 0.948
VAV2 1.591 250.398 27 0.126 0.110 0.086 0.524 0.846
GSK3B 0.000 471.029 33 0.569 0.217 0.162 0.637 1.585
IFITM1 0.000 183.973 28 0.402 0.058 0.066 0.204 0.730
LILRB3 1.938 812.840 30 0.445 0.371 0.319 0.781 1.915
RAC3 3.948 229.299 28 0.082 0.093 0.078 0.487 0.740
PRKCB 3.915 660.093 30 0.455 0.290 0.252 0.703 1.700
PPP3R1 1.931 492.695 32 0.476 0.228 0.190 0.623 1.517
CHUK 3.864 289.588 20 0.431 0.108 0.116 0.316 0.971
CD19 6.966 681.329 34 0.377 0.308 0.281 0.742 1.709
IKBKB 0.000 373.450 30 0.369 0.175 0.129 0.692 1.365
FCGR2B 7.021 1002.259 32 0.897 0.424 0.352 0.723 2.396
PLCG2 1.938 522.334 29 0.445 0.244 0.190 0.726 1.605
PPP3CC 3.384 1179.474 34 0.589 0.542 0.429 0.897 2.457
PPP3CA 1.745 181.700 22 0.190 0.067 0.069 0.295 0.621
NFAT5 1.496 309.801 34 0.250 0.134 0.105 0.550 1.040
BTK 3.218 468.781 30 0.530 0.230 0.162 0.686 1.608
MAPK3 1.572 267.238 33 0.352 0.106 0.089 0.421 0.968
PIK3R3 0.000 415.137 30 0.459 0.193 0.149 0.630 1.431
CD81 3.569 629.601 24 0.584 0.297 0.233 0.667 1.782
CD79A 1.848 453.353 37 0.397 0.196 0.166 0.648 1.407