GNRH_SIGNALING_PATHWAY

Differential Network Properties
Rewiring Score: 1.903 Mean Expression: 13.224
Gene count: 54 Rewired gene count: 44
Disease Potential: 0.001 Pathway centrality: 0.129
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Gene Symbol Rewiring Score (local) Rewiring Score (Global) Degree Clustering coefficient Betweeness Page Rank Closeness Overall Global centrality
MMP14 0.000 672.119 40 0.544 0.315 0.250 0.724 1.833
MAP2K7 0.000 251.896 36 0.269 0.103 0.090 0.422 0.885
ADCY1 15.313 1755.269 45 0.738 0.718 0.634 0.900 2.990
PLA2G4A 1.568 261.095 33 0.468 0.103 0.095 0.363 1.030
ITPR2 5.913 365.297 44 0.230 0.165 0.144 0.627 1.166
MAPK10 16.610 949.790 45 0.066 0.448 0.406 0.891 1.811
PTK2B 3.877 341.860 31 0.312 0.152 0.133 0.534 1.130
FSHB 3.395 672.464 43 0.450 0.336 0.245 0.830 1.861
GNRH1 5.019 459.843 39 0.417 0.204 0.181 0.596 1.399
PLD1 3.370 454.106 44 0.509 0.214 0.160 0.635 1.518
MAP2K6 5.487 300.193 33 0.266 0.133 0.106 0.558 1.063
PRKCB 5.014 660.093 39 0.455 0.290 0.252 0.703 1.700
GNAS 7.268 463.332 45 0.276 0.201 0.179 0.636 1.292
PRKACA 3.858 686.553 44 0.504 0.323 0.243 0.769 1.839
PLA2G1B 7.233 987.869 45 0.568 0.452 0.377 0.813 2.211
CAMK2A 5.189 455.912 39 0.363 0.212 0.182 0.595 1.353
ADCY3 1.656 404.527 41 0.374 0.177 0.160 0.494 1.205
MAPK11 7.097 398.356 43 0.389 0.167 0.151 0.495 1.201
MAPK3 4.376 267.238 41 0.352 0.106 0.089 0.421 0.968
ATF4 1.535 632.083 38 0.479 0.293 0.243 0.705 1.719
PRKCD 8.390 1041.195 37 0.898 0.464 0.363 0.738 2.463
PRKACG 8.149 624.628 44 0.518 0.291 0.222 0.761 1.792
PLCB4 8.547 406.178 44 0.379 0.159 0.167 0.476 1.180
PLA2G6 6.444 1159.921 46 0.402 0.532 0.457 0.871 2.263
PLA2G5 6.797 550.673 37 0.521 0.269 0.198 0.681 1.670
MAP2K4 0.000 137.717 28 0.283 0.040 0.040 0.147 0.510
PLCB2 3.276 680.273 41 0.565 0.300 0.260 0.663 1.788
ADCY9 0.000 307.466 38 0.374 0.126 0.116 0.481 1.096
ITPR1 3.987 588.351 42 0.178 0.274 0.237 0.722 1.411
ADCY6 3.204 607.817 38 0.601 0.273 0.224 0.624 1.722
LHB 5.169 1055.215 46 0.735 0.499 0.376 0.834 2.445
SRC 3.140 858.035 41 0.658 0.414 0.310 0.819 2.201
PRKACB 0.000 224.259 40 0.066 0.100 0.081 0.497 0.745
GNRH2 1.630 336.712 46 0.330 0.150 0.114 0.612 1.207
PLA2G10 12.696 1641.637 42 0.592 0.736 0.629 0.970 2.926
ADCY7 0.000 296.273 32 0.313 0.109 0.131 0.231 0.785
GNAQ 0.000 220.168 32 0.218 0.087 0.077 0.387 0.770
GNRHR 4.874 369.040 44 0.057 0.183 0.138 0.723 1.101
GRB2 0.000 208.312 38 0.277 0.081 0.071 0.372 0.801
ADCY8 3.633 302.024 38 0.188 0.139 0.112 0.551 0.990
PLA2G2A 2.133 97.289 21 0.250 0.012 0.022 0.013 0.297
ADCY2 9.078 289.109 43 0.165 0.140 0.099 0.655 1.059
SOS1 0.000 296.429 41 0.210 0.129 0.112 0.497 0.948
MAPK13 6.961 916.647 45 0.644 0.422 0.333 0.827 2.226
CACNA1S 3.214 426.104 44 0.399 0.196 0.151 0.676 1.422
CACNA1D 10.162 569.328 43 0.390 0.275 0.214 0.764 1.643
MAPK12 3.041 284.347 32 0.292 0.101 0.122 0.319 0.834
MMP2 1.568 387.499 40 0.107 0.172 0.154 0.614 1.047
CALML3 1.641 359.379 43 0.363 0.166 0.133 0.590 1.252
CAMK2B 6.872 712.376 39 0.509 0.341 0.252 0.756 1.857
ITPR3 1.606 173.952 34 0.182 0.055 0.055 0.300 0.592
MAP2K3 3.488 394.896 39 0.476 0.182 0.140 0.634 1.431
MAP3K3 3.492 818.123 48 0.671 0.370 0.290 0.756 2.086