CALCIUM_SIGNALING_PATHWAY

Differential Network Properties
Rewiring Score: 0.283 Mean Expression: 21.566
Gene count: 102 Rewired gene count: 98
Disease Potential: 0.001 Pathway centrality: 0.274
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Gene Symbol Rewiring Score (local) Rewiring Score (Global) Degree Clustering coefficient Betweeness Page Rank Closeness Overall Global centrality
PPP3CA 2.348 181.700 59 0.190 0.067 0.069 0.295 0.621
BST1 3.565 255.408 80 0.128 0.107 0.094 0.497 0.825
CCKAR 11.872 745.524 94 0.560 0.341 0.275 0.774 1.950
PRKACG 14.297 624.628 93 0.518 0.291 0.222 0.761 1.792
SPHK2 20.852 976.774 80 0.432 0.459 0.382 0.830 2.104
ADRB3 8.272 346.362 84 0.213 0.157 0.131 0.625 1.126
ITPKB 22.612 1765.200 86 0.973 0.633 0.620 0.791 3.017
GRPR 11.054 506.172 89 0.469 0.235 0.180 0.731 1.615
AVPR1B 3.583 398.806 82 0.336 0.163 0.155 0.549 1.203
PRKACA 4.695 686.553 90 0.504 0.323 0.243 0.769 1.839
ATP2B4 20.521 791.634 84 0.354 0.354 0.324 0.800 1.832
CACNA1A 3.039 271.029 78 0.200 0.110 0.107 0.398 0.815
PRKCB 12.693 660.093 79 0.455 0.290 0.252 0.703 1.700
PTK2B 3.433 341.860 74 0.312 0.152 0.133 0.534 1.130
MYLK 6.239 464.695 69 0.115 0.216 0.187 0.662 1.180
GRIN2A 8.724 527.746 89 0.485 0.248 0.183 0.731 1.647
NOS1 11.450 534.555 82 0.428 0.253 0.215 0.654 1.550
TNNC2 9.961 407.167 81 0.317 0.184 0.159 0.605 1.265
P2RX3 14.762 780.150 83 0.494 0.355 0.303 0.788 1.940
ADCY1 33.939 1755.269 86 0.738 0.718 0.634 0.900 2.990
PLCG2 12.547 522.334 84 0.445 0.244 0.190 0.726 1.605
TACR1 12.224 506.738 83 0.674 0.241 0.172 0.647 1.733
PPP3CC 7.289 1179.474 95 0.589 0.542 0.429 0.897 2.457
SLC8A1 9.889 836.009 94 0.552 0.412 0.308 0.861 2.134
HTR4 22.647 1229.928 92 0.658 0.508 0.448 0.825 2.439
CAMK4 19.217 1141.007 90 0.381 0.537 0.448 0.929 2.296
ITPR3 1.895 173.952 62 0.182 0.055 0.055 0.300 0.592
HTR2B 13.580 459.780 87 0.694 0.192 0.148 0.555 1.588
GRM5 15.861 633.972 91 0.303 0.302 0.252 0.791 1.648
CALML3 11.087 359.379 86 0.363 0.166 0.133 0.590 1.252
CACNA1G 15.943 621.825 94 0.304 0.300 0.244 0.768 1.616
TACR3 7.912 599.177 91 0.387 0.274 0.244 0.657 1.562
CACNA1D 9.557 569.328 82 0.390 0.275 0.214 0.764 1.643
P2RX5 3.768 218.521 82 0.102 0.087 0.075 0.454 0.718
HTR6 8.944 303.822 85 0.503 0.132 0.104 0.515 1.254
HTR2C 11.719 623.142 87 0.353 0.281 0.257 0.692 1.582
EDNRB 19.623 1308.275 86 0.818 0.563 0.459 0.828 2.668
ADCY7 1.975 296.273 62 0.313 0.109 0.131 0.231 0.785
PDE1A 0.000 139.213 78 0.088 0.043 0.035 0.285 0.451
ADRA1D 8.262 721.336 86 0.621 0.331 0.263 0.728 1.943
PRKACB 6.150 224.259 74 0.066 0.100 0.081 0.497 0.745
CACNA1B 21.545 1216.106 90 0.693 0.535 0.436 0.834 2.498
ATP2A3 3.446 426.209 60 0.414 0.186 0.178 0.471 1.249
HTR2A 14.458 585.857 93 0.388 0.296 0.220 0.742 1.645
ITPR1 14.065 588.351 83 0.178 0.274 0.237 0.722 1.411
ADCY9 3.834 307.466 72 0.374 0.126 0.116 0.481 1.096
CACNA1E 10.892 343.555 83 0.218 0.161 0.122 0.617 1.118
PLCB2 10.229 680.273 87 0.565 0.300 0.260 0.663 1.788
RYR3 16.581 359.394 92 0.249 0.167 0.129 0.684 1.229
P2RX6 11.802 295.100 86 0.231 0.136 0.101 0.599 1.067
PLCB4 7.356 406.178 74 0.379 0.159 0.167 0.476 1.180
NOS2 10.347 543.377 86 0.687 0.234 0.183 0.618 1.722
AGTR1 1.486 267.534 81 0.086 0.107 0.104 0.485 0.782
PDE1B 5.796 558.964 90 0.370 0.264 0.213 0.740 1.587
PLN 3.624 556.280 81 0.326 0.246 0.231 0.650 1.453
BDKRB1 5.402 345.641 90 0.315 0.160 0.121 0.603 1.198
SLC8A2 8.956 464.783 87 0.520 0.202 0.167 0.634 1.523
GRIN2C 11.107 375.210 88 0.292 0.174 0.140 0.655 1.262
ADCY3 1.469 404.527 79 0.374 0.177 0.160 0.494 1.205
CAMK2A 8.755 455.912 82 0.363 0.212 0.182 0.595 1.353
HTR7 3.334 300.796 81 0.454 0.119 0.098 0.479 1.150
GNAS 4.396 463.332 87 0.276 0.201 0.179 0.636 1.292
CD38 4.648 416.537 82 0.532 0.174 0.158 0.554 1.418
ADRB1 5.015 253.241 80 0.245 0.098 0.094 0.450 0.886
TBXA2R 11.507 457.642 85 0.358 0.209 0.166 0.637 1.371
ATP2B2 5.295 315.334 94 0.226 0.132 0.112 0.558 1.027
GNAL 3.179 691.433 87 0.698 0.327 0.246 0.714 1.985
CACNA1H 13.129 752.557 84 0.455 0.365 0.289 0.788 1.897
PLCG1 11.127 797.518 93 0.329 0.362 0.315 0.783 1.789
PPP3R1 5.280 492.695 80 0.476 0.228 0.190 0.623 1.517
CHRNA7 3.379 235.923 75 0.235 0.096 0.078 0.395 0.804
GRIN2D 6.931 323.632 80 0.226 0.146 0.113 0.594 1.078
ITPR2 5.297 365.297 81 0.230 0.165 0.144 0.627 1.166
PTAFR 12.056 616.322 92 0.458 0.275 0.235 0.718 1.685
VDAC3 1.535 245.401 71 0.424 0.100 0.087 0.417 1.027
DRD5 5.198 341.207 89 0.306 0.163 0.115 0.658 1.243
RYR2 4.836 628.839 88 0.460 0.277 0.244 0.612 1.594
HRH1 5.360 203.131 65 0.171 0.067 0.073 0.403 0.715
CAMK2B 12.463 712.376 88 0.509 0.341 0.252 0.756 1.857
VDAC1 2.224 385.825 66 0.243 0.170 0.159 0.531 1.103
ERBB4 6.253 408.652 78 0.372 0.182 0.160 0.579 1.294
EDNRA 3.321 234.339 76 0.108 0.105 0.092 0.529 0.834
CACNA1S 8.336 426.104 84 0.399 0.196 0.151 0.676 1.422
P2RX7 27.472 2149.907 89 0.823 0.823 0.763 0.903 3.311
ADCY2 11.096 289.109 91 0.165 0.140 0.099 0.655 1.059
SLC25A5 5.252 382.746 68 0.259 0.173 0.147 0.620 1.198
ADCY8 8.127 302.024 72 0.188 0.139 0.112 0.551 0.990
GNA15 8.355 683.456 78 0.590 0.280 0.288 0.558 1.715
PTGER1 4.901 290.638 80 0.152 0.120 0.110 0.407 0.789
NOS3 3.841 226.779 77 0.141 0.088 0.080 0.453 0.762
GRM1 18.330 1512.912 83 0.777 0.620 0.545 0.839 2.781
ATP2A2 2.224 161.868 42 0.246 0.054 0.049 0.294 0.643
CCKBR 22.362 1144.794 91 0.623 0.516 0.420 0.872 2.431
GNAQ 0.000 220.168 71 0.218 0.087 0.077 0.387 0.770
SLC25A4 28.973 1238.257 82 0.598 0.537 0.452 0.845 2.433
P2RX4 9.613 448.189 81 0.404 0.221 0.163 0.712 1.500
PTGER3 15.117 1298.241 91 0.465 0.604 0.505 0.930 2.504
DRD1 13.997 994.315 90 0.458 0.459 0.396 0.803 2.116
TRHR 18.776 599.526 85 0.424 0.294 0.221 0.785 1.723
RYR1 0.000 238.631 86 0.052 0.101 0.081 0.534 0.769
P2RX1 13.980 647.299 86 0.466 0.311 0.237 0.801 1.816