P53_SIGNALING_PATHWAY

Differential Network Properties
Rewiring Score: 4.927 Mean Expression: 12.782
Gene count: 28 Rewired gene count: 21
Disease Potential: 0.517 Pathway centrality: 0.050
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Gene Symbol Rewiring Score (local) Rewiring Score (Global) Degree Clustering coefficient Betweeness Page Rank Closeness Overall Global centrality
FAS 1.689 489.662 21 0.726 0.219 0.171 0.502 1.618
CASP8 3.265 350.114 18 0.186 0.147 0.157 0.527 1.017
BAX 0.000 819.276 21 0.457 0.385 0.315 0.756 1.914
BAI1 0.000 1001.333 20 0.550 0.475 0.379 0.826 2.230
PTEN 1.722 453.779 20 0.422 0.196 0.179 0.595 1.392
CCNE1 0.000 232.454 20 0.446 0.075 0.080 0.296 0.897
CDK4 0.000 415.322 19 0.289 0.189 0.155 0.621 1.255
CCNG1 2.238 281.304 21 0.440 0.118 0.095 0.472 1.124
CDKN1A 2.379 356.568 15 0.499 0.135 0.141 0.373 1.149
CDK6 1.722 275.689 21 0.422 0.113 0.100 0.480 1.114
IGFBP3 1.459 441.171 15 0.210 0.196 0.175 0.639 1.220
GADD45B 1.749 499.457 16 0.188 0.235 0.196 0.742 1.361
TNFRSF10B 2.379 191.464 12 0.503 0.061 0.070 0.088 0.722
APAF1 1.733 188.476 20 0.157 0.073 0.067 0.348 0.644
CCND2 1.595 279.640 18 0.252 0.112 0.103 0.482 0.949
TP53 2.114 562.111 22 0.308 0.229 0.267 0.520 1.323
ATR 2.108 323.123 17 0.527 0.139 0.129 0.423 1.218
TSC2 1.459 450.910 14 0.228 0.217 0.170 0.687 1.303
CDK2 1.689 1343.199 22 0.781 0.565 0.479 0.873 2.698
MDM2 2.238 890.853 22 0.369 0.417 0.353 0.856 1.996
GTSE1 0.000 279.318 22 0.244 0.125 0.096 0.553 1.018
DDB2 1.802 394.360 23 0.236 0.182 0.158 0.592 1.169
BBC3 3.397 716.749 18 0.523 0.340 0.271 0.767 1.900
CD82 0.000 787.252 20 0.503 0.362 0.304 0.769 1.938
CCND3 1.532 263.251 17 0.238 0.106 0.103 0.449 0.896
CHEK2 2.108 168.905 20 0.339 0.061 0.049 0.371 0.820
PPM1D 3.863 581.290 22 0.292 0.229 0.262 0.590 1.373