{"id":61,"date":"2021-12-07T06:22:04","date_gmt":"2021-12-07T06:22:04","guid":{"rendered":"http:\/\/tbioinfo.icgeb.res.in\/bioinfo\/?page_id=61"},"modified":"2024-12-06T04:51:32","modified_gmt":"2024-12-06T04:51:32","slug":"technologies","status":"publish","type":"page","link":"https:\/\/bioinfo.icgeb.res.in\/bioinfo\/index.php\/technologies\/","title":{"rendered":"Repositories"},"content":{"rendered":"<h1>Our Research Technologies:-<\/h1>\n<p>The scientific interests of his Group include the use of computational biology tools to solve research problems in the post-genomic era.<\/p>\n<ul>\n<li>Specifically, the group is interested in:-\n<ul>\n<li>Development and application of artificial intelligence-based methods to address complex biological data classification problems;<\/li>\n<li>Computer-aided drug designing; including molecular modeling, molecular dynamics, homology modeling, virtual screening and cheminformatics for lead identification;<\/li>\n<li>Application of comparative genomics methods to identify novel drug targets and gene expression regulatory elements like miRNAs and transcription factors;<\/li>\n<li>Applications for Systems Biology for translational bioinformatics;<\/li>\n<li>Computational and statistical analysis of NGS (Next Generation Sequence) data and;<\/li>\n<li>Development of biological databases and algorithms.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h1>Web Servers:-<\/h1>\n<ol>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/virulent\" target=\"_blank\" rel=\"noopener\">VirulentPred<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/vpred\/\" target=\"_blank\" rel=\"noopener\">VsupPred \u2013 It is a SVM based webserver for predicting viral suppressor proteins.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/duct-BRCA-CSP\/\" target=\"_blank\" rel=\"noopener\">Duct-BRPA-CSP &#8211; BRCA-CSP (Breast cancer stage prediction) is a web-bench developed for predicting Early and Late stage of invasive ductal carcinoma (IDC) patients using gene expression data derived from RNA-seq experiments in the form of RNA-Seq by RPKM values.<\/a><\/li>\n<li><a href=\"http:\/\/14.139.62.220\/ascovpred\" target=\"_blank\" rel=\"noopener\">ASCoVPred: A web server to predict anti-SARS-CoV-2 activity and human cell toxicity of molecules<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/ProtPathDB\/\" target=\"_blank\" rel=\"noopener\">ProtPathDB &#8211; A database for Pathogen and Parasite Proteases<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/PtDB\/\" target=\"_blank\" rel=\"noopener\">ApicoTFdb \u2013 Apicomplexans undergo a complex life cycle during its development across different tissues of vectors and host(s).<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/cdkipred\/\" target=\"_blank\" rel=\"noopener\">CDKIPred:- CDKIPred is a SVM based prediction method to identify novel cellular CDK inhibitor proteins using various features of proteins.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/faap\/\" target=\"_blank\" rel=\"noopener\">FaaPred:- Fungal adhesins and adhesin-like proteins prediction<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/kipho\/\" target=\"_blank\" rel=\"noopener\">KiPho \u2013 Protein phosphorylation\/dephosphorylation is one of the key Post-Translational Modifications (PTMs) process that is regulated by the kinases and phosphatases in the competitive manner.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/miRMOD\/\" target=\"_blank\" rel=\"noopener\">miRMOD:- miRNA modification prediction tool<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/mirtronP\/\" target=\"_blank\" rel=\"noopener\">MirtronPred:- Introns are known to be a common source of canonical microRNAs.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/pamirdb\/\" target=\"_blank\" rel=\"noopener\">PAmiRDB is a database of computationally predicted whole genome viral targets of plant miRNA.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/vpred\/\" target=\"_blank\" rel=\"noopener\">plant VsupPred:- plant VsupPred is a Random Forest based prediction tool to predict viral Suppressors of RNA silencing (VSRs).<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/pmirna\" target=\"_blank\" rel=\"noopener\">PmiRNA \u2013 Micro RNAs (miRNAs) are small RNAs of about 20 to 24 nucleotides, which regulate post-transcriptional gene expression in plants and animals.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/PRmePRed\" target=\"_blank\" rel=\"noopener\">PRmePRed \u2013 PRmePRed is an SVM based prediction tool to predict arginine methylation sites in proteins.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/cyclinpred\/\" target=\"_blank\" rel=\"noopener\">CyclinpPred:- CyclinPred is a SVM based prediction method to identify novel cyclins using various features of proteins.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/AHPR\/\" target=\"_blank\" rel=\"noopener\">AHPR \u2013 Present antiviral drugs against hepatitis are ineffective to deal with recent challenges of mixed, sporadic co-infections and cancer.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/APA\/\" target=\"_blank\" rel=\"noopener\">APA:- Altered Pathway Analyzer (APA) is a cross-platform and standalone tool for analyzing gene expression datasets to highlight significantly rewired pathways across case-vs-control conditions.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/gff\/\" target=\"_blank\" rel=\"noopener\">GFF-Ex:- A genome feature extraction package<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/pssm\/\" target=\"_blank\" rel=\"noopener\">PSSM and SSC to SVM converter<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/20sipred\/\" target=\"_blank\" rel=\"noopener\">20S iPred &#8211; 20S\u00a0iPred webserver assists in the classification of compounds as 20S proteasome inhibitors or non-inhibitors.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/proteasome\/\" target=\"_blank\" rel=\"noopener\">20sPred \u2013 The ubiquitin\/proteasome system plays a major role in overall protein turnover, in eukaryotic cells including plasmodia.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/3depipred\/\" target=\"_blank\" rel=\"noopener\">3DEpiPred- Identification of conformational B-cell epitopes in antigens is an important key step in rational vaccine design.<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/repeat_server\/protreps_4server.php\" target=\"_blank\" rel=\"noopener\">DIREP:- Direct Repeats Web Server<\/a><\/li>\n<\/ol>\n<h1>Databases<\/h1>\n<ol>\n<li><a href=\"https:\/\/bioinfo.icgeb.res.in\/gsmdb\/\" target=\"_blank\" rel=\"noopener\">Genomic SSRs Millets DataBase<\/a><\/li>\n<li><a href=\"https:\/\/bioinfo.icgeb.res.in\/psatdb\/\" target=\"_blank\" rel=\"noopener\">pSATdb 2.0<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/m3db\/\" target=\"_blank\" rel=\"noopener\">M3db- Meta-Analysis of Metastatic Melonama<\/a><\/li>\n<li><a href=\"http:\/\/bioinfo.icgeb.res.in\/protvirdb\/\" target=\"_blank\" rel=\"noopener\">ProtvirDB:- A database of protozoan virulenProtvirDB: -t proteins<\/a><\/li>\n<\/ol>\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Our Research Technologies:- The scientific interests of his Group include the use of computational biology tools to solve research problems in the post-genomic era. Specifically, the group is interested in:- Development and application of artificial intelligence-based methods to address complex biological data classification problems; Computer-aided drug designing; including molecular modeling, molecular dynamics, homology modeling, virtual [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template\/fullwidth.php","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/bioinfo.icgeb.res.in\/bioinfo\/index.php\/wp-json\/wp\/v2\/pages\/61"}],"collection":[{"href":"https:\/\/bioinfo.icgeb.res.in\/bioinfo\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bioinfo.icgeb.res.in\/bioinfo\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bioinfo.icgeb.res.in\/bioinfo\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bioinfo.icgeb.res.in\/bioinfo\/index.php\/wp-json\/wp\/v2\/comments?post=61"}],"version-history":[{"count":48,"href":"https:\/\/bioinfo.icgeb.res.in\/bioinfo\/index.php\/wp-json\/wp\/v2\/pages\/61\/revisions"}],"predecessor-version":[{"id":2323,"href":"https:\/\/bioinfo.icgeb.res.in\/bioinfo\/index.php\/wp-json\/wp\/v2\/pages\/61\/revisions\/2323"}],"wp:attachment":[{"href":"https:\/\/bioinfo.icgeb.res.in\/bioinfo\/index.php\/wp-json\/wp\/v2\/media?parent=61"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}