PF3D7_1230400 | ATP-dependent protease subunit ClpQ

UniProt_ID: Q8I5B6

Computed_GO_Component_IDs: GO:0009376 GO:0005839
Computed_GO_Components: HslUV protease complex proteasome core complex
Computed_GO_Function_IDs: GO:0004298
Computed_GO_Functions: threonine-type endopeptidase activity
Computed_GO_Process_IDs: GO:0006508 GO:0051603
Computed_GO_Processes: proteolysis proteolysis involved in cellular protein catabolic process
Curated_GO_Component_IDs: GO:0005739
Curated_GO_Components: mitochondrion
Curated_GO_Function_IDs: GO:0004176 GO:0003729 GO:0070011 GO:0005515
Curated_GO_Functions: ATP-dependent peptidase activity mRNA binding peptidase activity, acting on L-amino acid peptides protein binding
Curated_GO_Processes:

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	PF3D7_1230400	OTHER	0.548611	0.000465	0.450924

No Results

Fasta :-
>PF3D7_1230400 MFIRNFVNIIGSQKSITKTIARNYFSDNSKLIIPRHGTTILCVRKNNEVCLIGDGMVSQG TMIVKGNAKKIRRLKDNILMGFAGATADCFTLLDKFETKIDEYPNQLLRSCVELAKLWRT DRYLRHLEAVLIVADKDILLEVTGNGDVLEPSGNVLGTGSGGPYAMAAARALYDVENLSA KDIAYKAMNIAADMCCHTNNNFICETL
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/PF3D7_1230400.fa Sequence name : PF3D7_1230400 Sequence length : 207 VALUES OF COMPUTED PARAMETERS Coef20 : 4.444 CoefTot : -1.425 ChDiff : 3 ZoneTo : 47 KR : 8 DE : 1 CleavSite : 37 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 1.147 1.300 0.135 0.534 MesoH : -0.727 0.319 -0.366 0.222 MuHd_075 : 50.016 31.332 15.228 11.104 MuHd_095 : 31.873 21.647 9.430 9.045 MuHd_100 : 29.949 21.891 7.751 7.890 MuHd_105 : 38.998 30.048 11.029 10.187 Hmax_075 : 15.283 14.000 3.123 5.373 Hmax_095 : 7.200 11.900 0.375 4.769 Hmax_100 : 13.800 16.600 2.414 5.900 Hmax_105 : 15.100 21.800 3.468 7.350 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.0154 0.9846 DFMC : 0.0396 0.9604 This protein is probably imported in mitochondria. f(Ser) = 0.0851 f(Arg) = 0.0851 CMi = 0.44994 CMi is the Chloroplast/Mitochondria Index It has been proposed by Von Heijne et al (Eur J Biochem,1989, 180: 535-545)

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 207 PF3D7_1230400 MFIRNFVNIIGSQKSITKTIARNYFSDNSKLIIPRHGTTILCVRKNNEVCLIGDGMVSQGTMIVKGNAKKIRRLKDNILM 80 GFAGATADCFTLLDKFETKIDEYPNQLLRSCVELAKLWRTDRYLRHLEAVLIVADKDILLEVTGNGDVLEPSGNVLGTGS 160 GGPYAMAAARALYDVENLSAKDIAYKAMNIAADMCCHTNNNFICETL 240 ................................................................................ 80 ................................................................................ 160 ............................................... 240 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ PF3D7_1230400 4 ---MFIR|NF 0.092 . PF3D7_1230400 14 NIIGSQK|SI 0.080 . PF3D7_1230400 18 SQKSITK|TI 0.062 . PF3D7_1230400 22 ITKTIAR|NY 0.080 . PF3D7_1230400 30 YFSDNSK|LI 0.069 . PF3D7_1230400 35 SKLIIPR|HG 0.096 . PF3D7_1230400 44 TTILCVR|KN 0.077 . PF3D7_1230400 45 TILCVRK|NN 0.087 . PF3D7_1230400 65 QGTMIVK|GN 0.066 . PF3D7_1230400 69 IVKGNAK|KI 0.065 . PF3D7_1230400 70 VKGNAKK|IR 0.080 . PF3D7_1230400 72 GNAKKIR|RL 0.152 . PF3D7_1230400 73 NAKKIRR|LK 0.171 . PF3D7_1230400 75 KKIRRLK|DN 0.167 . PF3D7_1230400 95 CFTLLDK|FE 0.058 . PF3D7_1230400 99 LDKFETK|ID 0.060 . PF3D7_1230400 109 YPNQLLR|SC 0.099 . PF3D7_1230400 116 SCVELAK|LW 0.062 . PF3D7_1230400 119 ELAKLWR|TD 0.085 . PF3D7_1230400 122 KLWRTDR|YL 0.320 . PF3D7_1230400 125 RTDRYLR|HL 0.285 . PF3D7_1230400 136 VLIVADK|DI 0.067 . PF3D7_1230400 170 YAMAAAR|AL 0.143 . PF3D7_1230400 181 VENLSAK|DI 0.083 . PF3D7_1230400 186 AKDIAYK|AM 0.067 . ____________________________^_________________

Fasta :-
>PF3D7_1230400 ATGTTTATCAGAAACTTTGTAAATATAATTGGATCACAAAAATCAATAACCAAAACAATT GCTAGAAATTATTTTTCTGATAACAGCAAGTTGATAATTCCTCGTCATGGAACTACCATA TTATGTGTTAGGAAAAATAATGAAGTGTGTTTGATCGGTGATGGAATGGTTTCTCAAGGA ACGATGATAGTTAAGGGAAATGCAAAAAAGATAAGACGTTTAAAGGACAATATATTAATG GGTTTCGCAGGAGCTACAGCGGATTGTTTTACCTTGCTAGATAAATTTGAGACAAAGATT GATGAATATCCAAATCAACTTTTGAGAAGTTGTGTTGAGTTAGCCAAACTTTGGAGAACT GATAGATATTTAAGACATTTAGAGGCCGTTTTAATAGTGGCTGATAAGGATATTTTGTTA GAAGTAACCGGTAATGGTGATGTTTTAGAACCATCAGGAAATGTTTTAGGAACAGGATCA GGAGGTCCATATGCTATGGCAGCTGCAAGAGCATTGTATGATGTCGAAAATTTAAGTGCT AAAGATATAGCTTATAAAGCTATGAATATTGCTGCAGATATGTGTTGTCATACTAATAAT AATTTTATTTGTGAAACATTGTAA
Download Fasta

Fasta :-

MFIRNFVNIIGSQKSITKTIARNYFSDNSKLIIPRHGTTILCVRKNNEVCLIGDGMVSQG TMIVKGNAKKIRRLKDNILMGFAGATADCFTLLDKFETKIDEYPNQLLRSCVELAKLWRT DRYLRHLEAVLIVADKDILLEVTGNGDVLEPSGNVLGTGSGGPYAMAAARALYDVENLSA KDIAYKAMNIAADMCCHTNNNFICETL

Proteasome subunits

title: active site
coordinates: T38,D54,M56,K70,S160

PF3D7_1230400.pdb

PF3D7_1230400_site1.pdb

PF3D7_1230400_site2.pdb

No Results

	ID	Site	Peptide	Score	Method
	PF3D7_1230400	179 S	VENLSAKDI	0.996	unsp

PF3D7_1230400 | ATP-dependent protease subunit ClpQ

ID's

UniProt_ID: Q8I5B6

GEO Functions

Computed_GO_Component_IDs: GO:0009376 GO:0005839

Computed_GO_Components: HslUV protease complex proteasome core complex

Computed_GO_Function_IDs: GO:0004298

Computed_GO_Functions: threonine-type endopeptidase activity

Computed_GO_Process_IDs: GO:0006508 GO:0051603

Computed_GO_Processes: proteolysis proteolysis involved in cellular protein catabolic process

Curated_GO_Component_IDs: GO:0005739

Curated_GO_Components: mitochondrion

Curated_GO_Function_IDs: GO:0004176 GO:0003729 GO:0070011 GO:0005515

Curated_GO_Functions: ATP-dependent peptidase activity mRNA binding peptidase activity, acting on L-amino acid peptides protein binding

Curated_GO_Processes:

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Proteasome subunits

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

2277.t00293 MAL12P1.293 PFL1465c

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India