PF3D7_1247800 | dipeptidyl aminopeptidase 2

UniProt_ID: Q8I0V1

Computed_GO_Component_IDs:
Computed_GO_Components:
Computed_GO_Function_IDs: GO:0008234
Computed_GO_Functions: cysteine-type peptidase activity
Computed_GO_Process_IDs: GO:0006508
Computed_GO_Processes: proteolysis
Curated_GO_Component_IDs: GO:0071944 GO:0005737 GO:0044310
Curated_GO_Components: cell periphery cytoplasm osmiophilic body
Curated_GO_Function_IDs: GO:0008239
Curated_GO_Functions: dipeptidyl-peptidase activity
Curated_GO_Processes: exit from host cell proteolysis

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	PF3D7_1247800	SP	0.001124	0.998846	0.000030	CS pos: 19-20. VKG-DL. Pr: 0.8295

No Results

Fasta :-
>PF3D7_1247800 MNTFYIFFLFVLTTCFVKGDLPIHALMGDVSGIWKIKQTKKMSQKPEHCGGGIPNRNLDN LNPSIRNYQRFLENEYGNLDMMIVNLTMEKVKIINQEKPRDKWTYLAVRDYERNEIIGHW TMVYDEGFEIRLNGSKYFAFFKYERKSNAHCPTSIEDKSYNDRDCYKTNPTQTHIGWVLN EKVKENTKEKIFYWGCFYAEKKESTPVSSFVLHNGMENKTNLVESHDYHFEEKKKKNLPP IGRRSNYKKFRFSNLQKIYGSTQTHLRDIYGRSGERKYGCRKRDILNLKIRLTLPKQFSW GDPFNDENFEENVDDQKDCGSCYSISSVYSLERRFEILFWKKYKKKVNMPRLSHQSILSC SPYNQGCDGGYPFLVGKHMYEYGIIPEQYMHYENNDYNNCIMDMGNYNHLNKQNRNIKEI YYVSDYNYINGCYECTNEYEMMNEIILNGPIVAAINATSELLNFYNIEDKNVVYDILPKD THQVCDVPNKGFNGWQQTNHAINIVGWGEQIINQDKIKNDDANNNNNDNNHKLVKYWIIR NTWGKNWGYKGYLKFQRGINLAGIESQAVYIDPDFSRGYPKNILQSDSLE
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/PF3D7_1247800.fa Sequence name : PF3D7_1247800 Sequence length : 590 VALUES OF COMPUTED PARAMETERS Coef20 : 4.335 CoefTot : -0.410 ChDiff : 6 ZoneTo : 19 KR : 1 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 2.112 1.882 0.301 0.709 MesoH : -1.037 -0.092 -0.545 0.168 MuHd_075 : 10.886 12.046 4.683 3.551 MuHd_095 : 15.587 10.650 4.808 3.763 MuHd_100 : 4.774 4.447 1.883 1.667 MuHd_105 : 11.136 4.603 1.667 1.717 Hmax_075 : 16.450 18.800 4.288 6.320 Hmax_095 : 22.200 21.700 4.591 7.290 Hmax_100 : 18.600 16.700 3.778 5.890 Hmax_105 : 18.783 16.700 3.003 5.900 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.8890 0.1110 DFMC : 0.9007 0.0993

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 590 PF3D7_1247800 MNTFYIFFLFVLTTCFVKGDLPIHALMGDVSGIWKIKQTKKMSQKPEHCGGGIPNRNLDNLNPSIRNYQRFLENEYGNLD 80 MMIVNLTMEKVKIINQEKPRDKWTYLAVRDYERNEIIGHWTMVYDEGFEIRLNGSKYFAFFKYERKSNAHCPTSIEDKSY 160 NDRDCYKTNPTQTHIGWVLNEKVKENTKEKIFYWGCFYAEKKESTPVSSFVLHNGMENKTNLVESHDYHFEEKKKKNLPP 240 IGRRSNYKKFRFSNLQKIYGSTQTHLRDIYGRSGERKYGCRKRDILNLKIRLTLPKQFSWGDPFNDENFEENVDDQKDCG 320 SCYSISSVYSLERRFEILFWKKYKKKVNMPRLSHQSILSCSPYNQGCDGGYPFLVGKHMYEYGIIPEQYMHYENNDYNNC 400 IMDMGNYNHLNKQNRNIKEIYYVSDYNYINGCYECTNEYEMMNEIILNGPIVAAINATSELLNFYNIEDKNVVYDILPKD 480 THQVCDVPNKGFNGWQQTNHAINIVGWGEQIINQDKIKNDDANNNNNDNNHKLVKYWIIRNTWGKNWGYKGYLKFQRGIN 560 LAGIESQAVYIDPDFSRGYPKNILQSDSLE 640 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ................................................................................ 480 ................................................................................ 560 .............................. 640 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ PF3D7_1247800 18 LTTCFVK|GD 0.058 . PF3D7_1247800 35 DVSGIWK|IK 0.065 . PF3D7_1247800 37 SGIWKIK|QT 0.068 . PF3D7_1247800 40 WKIKQTK|KM 0.075 . PF3D7_1247800 41 KIKQTKK|MS 0.130 . PF3D7_1247800 45 TKKMSQK|PE 0.078 . PF3D7_1247800 56 GGGIPNR|NL 0.106 . PF3D7_1247800 66 NLNPSIR|NY 0.096 . PF3D7_1247800 70 SIRNYQR|FL 0.134 . PF3D7_1247800 90 VNLTMEK|VK 0.054 . PF3D7_1247800 92 LTMEKVK|II 0.073 . PF3D7_1247800 98 KIINQEK|PR 0.060 . PF3D7_1247800 100 INQEKPR|DK 0.157 . PF3D7_1247800 102 QEKPRDK|WT 0.070 . PF3D7_1247800 109 WTYLAVR|DY 0.107 . PF3D7_1247800 113 AVRDYER|NE 0.086 . PF3D7_1247800 131 DEGFEIR|LN 0.101 . PF3D7_1247800 136 IRLNGSK|YF 0.057 . PF3D7_1247800 142 KYFAFFK|YE 0.068 . PF3D7_1247800 145 AFFKYER|KS 0.080 . PF3D7_1247800 146 FFKYERK|SN 0.100 . PF3D7_1247800 158 PTSIEDK|SY 0.087 . PF3D7_1247800 163 DKSYNDR|DC 0.134 . PF3D7_1247800 167 NDRDCYK|TN 0.069 . PF3D7_1247800 182 GWVLNEK|VK 0.056 . PF3D7_1247800 184 VLNEKVK|EN 0.068 . PF3D7_1247800 188 KVKENTK|EK 0.055 . PF3D7_1247800 190 KENTKEK|IF 0.072 . PF3D7_1247800 201 GCFYAEK|KE 0.061 . PF3D7_1247800 202 CFYAEKK|ES 0.088 . PF3D7_1247800 219 HNGMENK|TN 0.062 . PF3D7_1247800 233 DYHFEEK|KK 0.058 . PF3D7_1247800 234 YHFEEKK|KK 0.072 . PF3D7_1247800 235 HFEEKKK|KN 0.083 . PF3D7_1247800 236 FEEKKKK|NL 0.125 . PF3D7_1247800 243 NLPPIGR|RS 0.072 . PF3D7_1247800 244 LPPIGRR|SN 0.233 . PF3D7_1247800 248 GRRSNYK|KF 0.073 . PF3D7_1247800 249 RRSNYKK|FR 0.192 . PF3D7_1247800 251 SNYKKFR|FS 0.125 . PF3D7_1247800 257 RFSNLQK|IY 0.083 . PF3D7_1247800 267 STQTHLR|DI 0.105 . PF3D7_1247800 272 LRDIYGR|SG 0.155 . PF3D7_1247800 276 YGRSGER|KY 0.074 . PF3D7_1247800 277 GRSGERK|YG 0.159 . PF3D7_1247800 281 ERKYGCR|KR 0.080 . PF3D7_1247800 282 RKYGCRK|RD 0.069 . PF3D7_1247800 283 KYGCRKR|DI 0.211 . PF3D7_1247800 289 RDILNLK|IR 0.060 . PF3D7_1247800 291 ILNLKIR|LT 0.126 . PF3D7_1247800 296 IRLTLPK|QF 0.078 . PF3D7_1247800 317 ENVDDQK|DC 0.070 . PF3D7_1247800 333 SVYSLER|RF 0.080 . PF3D7_1247800 334 VYSLERR|FE 0.102 . PF3D7_1247800 341 FEILFWK|KY 0.065 . PF3D7_1247800 342 EILFWKK|YK 0.088 . PF3D7_1247800 344 LFWKKYK|KK 0.063 . PF3D7_1247800 345 FWKKYKK|KV 0.120 . PF3D7_1247800 346 WKKYKKK|VN 0.121 . PF3D7_1247800 351 KKVNMPR|LS 0.119 . PF3D7_1247800 377 YPFLVGK|HM 0.067 . PF3D7_1247800 412 NYNHLNK|QN 0.066 . PF3D7_1247800 415 HLNKQNR|NI 0.126 . PF3D7_1247800 418 KQNRNIK|EI 0.131 . PF3D7_1247800 470 FYNIEDK|NV 0.061 . PF3D7_1247800 479 VYDILPK|DT 0.072 . PF3D7_1247800 490 VCDVPNK|GF 0.070 . PF3D7_1247800 516 QIINQDK|IK 0.059 . PF3D7_1247800 518 INQDKIK|ND 0.074 . PF3D7_1247800 532 NNDNNHK|LV 0.064 . PF3D7_1247800 535 NNHKLVK|YW 0.077 . PF3D7_1247800 540 VKYWIIR|NT 0.093 . PF3D7_1247800 545 IRNTWGK|NW 0.094 . PF3D7_1247800 550 GKNWGYK|GY 0.085 . PF3D7_1247800 554 GYKGYLK|FQ 0.061 . PF3D7_1247800 557 GYLKFQR|GI 0.101 . PF3D7_1247800 577 IDPDFSR|GY 0.102 . PF3D7_1247800 581 FSRGYPK|NI 0.071 . ____________________________^_________________

Fasta :-
>PF3D7_1247800 ATGAATACTTTTTATATTTTCTTTTTATTTGTGCTGACGACATGCTTCGTAAAGGGTGAT TTACCAATACATGCTCTTATGGGAGATGTATCAGGAATATGGAAAATAAAACAAACAAAA AAGATGAGCCAAAAACCTGAACATTGTGGTGGGGGTATACCCAATAGAAATTTGGATAAC TTAAACCCAAGTATAAGAAATTATCAAAGATTTTTGGAGAATGAATATGGGAACTTAGAC ATGATGATTGTGAACTTAACAATGGAAAAAGTAAAAATAATTAATCAAGAAAAGCCAAGA GATAAATGGACATATCTTGCTGTGAGAGATTATGAAAGGAATGAAATTATTGGTCATTGG ACCATGGTATATGACGAAGGCTTCGAAATAAGATTGAATGGAAGCAAATATTTCGCTTTT TTCAAATATGAAAGAAAATCAAATGCACATTGCCCTACCTCAATTGAAGACAAAAGTTAT AATGATAGAGATTGTTACAAAACAAATCCGACGCAAACACATATTGGATGGGTACTCAAT GAGAAAGTTAAAGAAAATACAAAAGAAAAAATTTTTTATTGGGGATGTTTTTATGCTGAG AAGAAAGAAAGTACGCCTGTATCTTCTTTTGTCCTTCATAATGGGATGGAAAATAAAACG AATTTAGTAGAAAGTCATGATTATCATTTTGAAGAAAAAAAAAAAAAAAATCTGCCTCCT ATTGGAAGGAGATCAAATTATAAAAAGTTCCGATTTTCCAACCTACAAAAAATATATGGA TCAACACAAACGCACCTGAGGGATATCTATGGGCGCTCAGGTGAGCGAAAGTATGGATGC AGAAAAAGAGATATTTTGAATTTAAAGATACGACTAACATTACCAAAACAATTTAGTTGG GGAGACCCCTTTAACGATGAAAATTTTGAAGAAAACGTAGATGACCAAAAAGATTGTGGT AGTTGTTATTCTATATCTAGTGTGTATAGTTTAGAAAGAAGGTTCGAAATATTATTTTGG AAGAAATATAAGAAAAAAGTAAATATGCCTAGATTGTCTCATCAATCAATATTAAGTTGT TCTCCATATAATCAAGGATGTGATGGAGGGTACCCATTTTTAGTTGGAAAACATATGTAT GAATATGGTATAATACCTGAACAGTACATGCATTATGAAAATAATGATTACAATAACTGT ATTATGGATATGGGAAATTATAATCATTTAAATAAACAAAATAGAAATATAAAGGAAATT TATTATGTTTCAGATTATAATTATATAAATGGATGTTATGAATGTACTAATGAATATGAA ATGATGAATGAAATTATTTTGAATGGACCAATAGTTGCAGCTATTAATGCTACCTCAGAA TTGTTAAACTTTTATAATATAGAAGATAAAAATGTTGTTTATGATATCCTACCTAAAGAT ACTCATCAAGTATGTGATGTACCTAATAAAGGATTTAATGGATGGCAACAAACAAACCAT GCAATTAATATTGTAGGATGGGGTGAACAAATAATTAATCAAGATAAAATCAAAAACGAT GATGCTAACAATAATAATAATGACAATAATCATAAATTAGTAAAATATTGGATTATAAGA AATACATGGGGAAAAAACTGGGGATATAAAGGTTATCTCAAATTTCAAAGAGGAATTAAT TTAGCAGGTATTGAATCTCAAGCTGTTTATATCGACCCAGATTTTTCTAGAGGATACCCA AAGAATATACTTCAATCCGACTCTTTGGAATAA
Download Fasta

Fasta :-

MNTFYIFFLFVLTTCFVKGDLPIHALMGDVSGIWKIKQTKKMSQKPEHCGGGIPNRNLDN LNPSIRNYQRFLENEYGNLDMMIVNLTMEKVKIINQEKPRDKWTYLAVRDYERNEIIGHW TMVYDEGFEIRLNGSKYFAFFKYERKSNAHCPTSIEDKSYNDRDCYKTNPTQTHIGWVLN EKVKENTKEKIFYWGCFYAEKKESTPVSSFVLHNGMENKTNLVESHDYHFEEKKKKNLPP IGRRSNYKKFRFSNLQKIYGSTQTHLRDIYGRSGERKYGCRKRDILNLKIRLTLPKQFSW GDPFNDENFEENVDDQKDCGSCYSISSVYSLERRFEILFWKKYKKKVNMPRLSHQSILSC SPYNQGCDGGYPFLVGKHMYEYGIIPEQYMHYENNDYNNCIMDMGNYNHLNKQNRNIKEI YYVSDYNYINGCYECTNEYEMMNEIILNGPIVAAINATSELLNFYNIEDKNVVYDILPKD THQVCDVPNKGFNGWQQTNHAINIVGWGEQIINQDKIKNDDANNNNNDNNHKLVKYWIIR NTWGKNWGYKGYLKFQRGINLAGIESQAVYIDPDFSRGYPKNILQSDSLE

No Results

title: active site
coordinates: Q316,C322,H500,N541

PF3D7_1247800.pdb

PF3D7_1247800_site1.pdb

PF3D7_1247800_site2.pdb

PF3D7_1247800_site3.pdb

PF3D7_1247800_site4.pdb

PF3D7_1247800_site5.pdb

No Results

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	PF3D7_1247800	299 S	PKQFSWGDP	0.994	unsp	PF3D7_1247800	299 S	PKQFSWGDP	0.994	unsp	PF3D7_1247800	299 S	PKQFSWGDP	0.994	unsp	PF3D7_1247800	154 S	HCPTSIEDK	0.996	unsp	PF3D7_1247800	159 S	IEDKSYNDR	0.995	unsp

PF3D7_1247800 | dipeptidyl aminopeptidase 2

ID's

UniProt_ID: Q8I0V1

GEO Functions

Computed_GO_Component_IDs:

Computed_GO_Components:

Computed_GO_Function_IDs: GO:0008234

Computed_GO_Functions: cysteine-type peptidase activity

Computed_GO_Process_IDs: GO:0006508

Computed_GO_Processes: proteolysis

Curated_GO_Component_IDs: GO:0071944 GO:0005737 GO:0044310

Curated_GO_Components: cell periphery cytoplasm osmiophilic body

Curated_GO_Function_IDs: GO:0008239

Curated_GO_Functions: dipeptidyl-peptidase activity

Curated_GO_Processes: exit from host cell proteolysis

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

2277.t00458 MAL12P1.457 PFL2290w

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India