PF3D7_1407800 | plasmepsin IV

UniProt_ID: Q8IM16

Computed_GO_Component_IDs: GO:0016020
Computed_GO_Components: membrane
Computed_GO_Function_IDs:
Computed_GO_Functions:
Computed_GO_Process_IDs: GO:0006508
Computed_GO_Processes: proteolysis
Curated_GO_Component_IDs: GO:0020020 GO:0005634
Curated_GO_Components: food vacuole nucleus
Curated_GO_Function_IDs: GO:0004190
Curated_GO_Functions: aspartic-type endopeptidase activity
Curated_GO_Processes: hemoglobin catabolic process

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	PF3D7_1407800	OTHER	0.999870	0.000018	0.000112

No Results

Fasta :-
>PF3D7_1407800 MALTVKEEEFSNTLIKNASAFDRLKLGNLKNLKIQKKLQFLYLILFVLITGVFFFFLIGN FYSHRKLYQVIKNTKHTTIGFKIDRPHDKVLSSVLKNKLSTYVKESFKFFKSGYAQKGYL GSENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDSIGCSTKHLYD ASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIEVTDADDLEPIYSGSE FDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHVGYLTIGGIESDFYE GPLTYEKLNHDLYWQIDLDIHFGKYVMQKANAVVDSGTSTITAPTSFLNKFFRDMNVIKV PFLPLYVTTCDNDDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPALCMLYILPVDIDDNTF ILGDPFMRKYFTVFDYEKESVGFAVAKNL
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/PF3D7_1407800.fa Sequence name : PF3D7_1407800 Sequence length : 449 VALUES OF COMPUTED PARAMETERS Coef20 : 4.034 CoefTot : 0.150 ChDiff : -12 ZoneTo : 6 KR : 1 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 2.788 2.918 0.542 1.042 MesoH : -0.654 0.373 -0.402 0.235 MuHd_075 : 28.126 20.739 9.051 5.837 MuHd_095 : 17.770 14.125 6.103 4.273 MuHd_100 : 18.798 10.955 6.055 3.820 MuHd_105 : 20.912 10.912 6.037 3.997 Hmax_075 : 8.633 15.983 0.509 5.483 Hmax_095 : 6.400 12.400 0.350 4.500 Hmax_100 : 4.500 8.900 -0.160 3.250 Hmax_105 : -1.900 3.150 -2.703 2.135 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9426 0.0574 DFMC : 0.9429 0.0571

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 449 PF3D7_1407800 MALTVKEEEFSNTLIKNASAFDRLKLGNLKNLKIQKKLQFLYLILFVLITGVFFFFLIGNFYSHRKLYQVIKNTKHTTIG 80 FKIDRPHDKVLSSVLKNKLSTYVKESFKFFKSGYAQKGYLGSENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSAN 160 LWVPSVNCDSIGCSTKHLYDASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIEVTDADDLEPIYSGSE 240 FDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHVGYLTIGGIESDFYEGPLTYEKLNHDLYWQIDLDI 320 HFGKYVMQKANAVVDSGTSTITAPTSFLNKFFRDMNVIKVPFLPLYVTTCDNDDLPTLEFHSRNNKYTLEPEFYMDPLSD 400 IDPALCMLYILPVDIDDNTFILGDPFMRKYFTVFDYEKESVGFAVAKNL 480 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ................................................. 480 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ PF3D7_1407800 6 -MALTVK|EE 0.059 . PF3D7_1407800 16 FSNTLIK|NA 0.079 . PF3D7_1407800 23 NASAFDR|LK 0.105 . PF3D7_1407800 25 SAFDRLK|LG 0.055 . PF3D7_1407800 30 LKLGNLK|NL 0.057 . PF3D7_1407800 33 GNLKNLK|IQ 0.056 . PF3D7_1407800 36 KNLKIQK|KL 0.058 . PF3D7_1407800 37 NLKIQKK|LQ 0.091 . PF3D7_1407800 65 GNFYSHR|KL 0.112 . PF3D7_1407800 66 NFYSHRK|LY 0.082 . PF3D7_1407800 72 KLYQVIK|NT 0.068 . PF3D7_1407800 75 QVIKNTK|HT 0.070 . PF3D7_1407800 82 HTTIGFK|ID 0.059 . PF3D7_1407800 85 IGFKIDR|PH 0.110 . PF3D7_1407800 89 IDRPHDK|VL 0.091 . PF3D7_1407800 96 VLSSVLK|NK 0.058 . PF3D7_1407800 98 SSVLKNK|LS 0.070 . PF3D7_1407800 104 KLSTYVK|ES 0.072 . PF3D7_1407800 108 YVKESFK|FF 0.068 . PF3D7_1407800 111 ESFKFFK|SG 0.100 . PF3D7_1407800 117 KSGYAQK|GY 0.078 . PF3D7_1407800 147 GQIGTNK|QP 0.060 . PF3D7_1407800 176 SIGCSTK|HL 0.075 . PF3D7_1407800 185 YDASASK|SY 0.087 . PF3D7_1407800 189 ASKSYEK|DG 0.077 . PF3D7_1407800 193 YEKDGTK|VE 0.055 . PF3D7_1407800 204 YGSGTVR|GY 0.106 . PF3D7_1407800 209 VRGYFSK|DV 0.113 . PF3D7_1407800 222 DLSLPYK|FI 0.077 . PF3D7_1407800 250 ILGLGWK|DL 0.072 . PF3D7_1407800 265 PVVVELK|KQ 0.060 . PF3D7_1407800 266 VVVELKK|QN 0.074 . PF3D7_1407800 269 ELKKQNK|ID 0.063 . PF3D7_1407800 284 YLPVHDK|HV 0.087 . PF3D7_1407800 307 GPLTYEK|LN 0.058 . PF3D7_1407800 324 LDIHFGK|YV 0.130 . PF3D7_1407800 329 GKYVMQK|AN 0.074 . PF3D7_1407800 350 PTSFLNK|FF 0.073 . PF3D7_1407800 353 FLNKFFR|DM 0.132 . PF3D7_1407800 359 RDMNVIK|VP 0.060 . PF3D7_1407800 383 TLEFHSR|NN 0.093 . PF3D7_1407800 386 FHSRNNK|YT 0.164 . PF3D7_1407800 428 LGDPFMR|KY 0.097 . PF3D7_1407800 429 GDPFMRK|YF 0.077 . PF3D7_1407800 438 TVFDYEK|ES 0.053 . PF3D7_1407800 447 VGFAVAK|NL 0.073 . ____________________________^_________________

Fasta :-
>PF3D7_1407800 ATGGCTCTTACCGTTAAAGAAGAAGAATTTTCGAATACATTGATTAAAAATGCTTCAGCA TTTGATCGATTGAAATTAGGTAATTTGAAGAACTTGAAAATCCAGAAAAAGCTTCAGTTT TTATATTTAATATTGTTTGTCCTTATTACGGGTGTGTTTTTCTTTTTTTTGATTGGAAAT TTTTATTCACATCGCAAGTTGTATCAAGTTATTAAAAACACAAAACACACAACTATAGGA TTTAAAATTGATAGACCACATGATAAGGTTTTGAGCTCTGTATTGAAAAATAAATTAAGC ACATATGTAAAAGAGAGCTTCAAATTTTTTAAATCAGGTTATGCACAAAAAGGATATTTA GGAAGTGAAAATGACAGTATTGAATTAGATGATGTTGCTAATTTAATGTTTTATGGTGAA GGACAAATTGGAACTAATAAACAACCATTTATGTTTATTTTCGATACCGGTTCAGCTAAT TTATGGGTTCCAAGTGTAAATTGTGATTCCATTGGATGCAGTACTAAACATCTTTATGAT GCATCTGCATCTAAATCATATGAAAAAGATGGAACAAAGGTAGAAATATCTTACGGTTCA GGAACTGTTAGAGGATACTTTAGTAAAGATGTAATAAGCCTTGGAGATTTATCATTACCA TACAAATTTATTGAAGTTACAGATGCAGATGATTTAGAACCCATATATAGTGGTTCCGAA TTTGATGGTATCCTAGGTTTAGGATGGAAAGATTTATCCATTGGTTCTATTGATCCGGTT GTTGTTGAATTAAAGAAACAAAACAAAATCGACAATGCTTTATTTACATTTTATTTACCT GTTCATGATAAACACGTTGGTTATTTAACTATAGGTGGTATCGAAAGTGATTTTTATGAA GGACCTTTAACTTATGAAAAATTAAATCATGACTTATATTGGCAAATAGATTTAGATATA CACTTTGGTAAATATGTCATGCAAAAAGCAAATGCTGTTGTTGATAGTGGTACAAGTACT ATAACAGCACCAACCAGTTTTCTTAATAAATTCTTTAGAGATATGAATGTTATTAAAGTA CCATTCTTACCATTATATGTAACCACCTGTGATAACGATGATTTACCAACACTTGAATTC CATTCAAGAAATAATAAATACACATTAGAACCTGAATTCTATATGGACCCATTATCAGAT ATTGATCCAGCTCTATGTATGCTCTACATATTGCCTGTTGATATTGATGATAATACATTT ATTTTAGGAGATCCATTTATGAGAAAATATTTCACCGTTTTTGATTATGAAAAAGAAAGT GTTGGTTTTGCAGTAGCTAAAAATTTATAA
Download Fasta

Fasta :-

MALTVKEEEFSNTLIKNASAFDRLKLGNLKNLKIQKKLQFLYLILFVLITGVFFFFLIGN FYSHRKLYQVIKNTKHTTIGFKIDRPHDKVLSSVLKNKLSTYVKESFKFFKSGYAQKGYL GSENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDSIGCSTKHLYD ASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIEVTDADDLEPIYSGSE FDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHVGYLTIGGIESDFYE GPLTYEKLNHDLYWQIDLDIHFGKYVMQKANAVVDSGTSTITAPTSFLNKFFRDMNVIKV PFLPLYVTTCDNDDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPALCMLYILPVDIDDNTF ILGDPFMRKYFTVFDYEKESVGFAVAKNL

Pepsin-like

title: catalytic residue
coordinates: D155,D335

PF3D7_1407800.pdb

PF3D7_1407800_site1.pdb

PF3D7_1407800_site2.pdb

PF3D7_1407800_site3.pdb

PF3D7_1407800_site4.pdb

PF3D7_1407800_site5.pdb

No Results

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	PF3D7_1407800	213 S	KDVISLGDL	0.99	unsp	PF3D7_1407800	213 S	KDVISLGDL	0.99	unsp	PF3D7_1407800	213 S	KDVISLGDL	0.99	unsp	PF3D7_1407800	399 S	MDPLSDIDP	0.992	unsp	PF3D7_1407800	106 S	YVKESFKFF	0.992	unsp	PF3D7_1407800	186 S	SASKSYEKD	0.991	unsp

PF3D7_1407800 | plasmepsin IV

ID's

UniProt_ID: Q8IM16

GEO Functions

Computed_GO_Component_IDs: GO:0016020

Computed_GO_Components: membrane

Computed_GO_Function_IDs:

Computed_GO_Functions:

Computed_GO_Process_IDs: GO:0006508

Computed_GO_Processes: proteolysis

Curated_GO_Component_IDs: GO:0020020 GO:0005634

Curated_GO_Components: food vacuole nucleus

Curated_GO_Function_IDs: GO:0004190

Curated_GO_Functions: aspartic-type endopeptidase activity

Curated_GO_Processes: hemoglobin catabolic process

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Pepsin-like

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

PF14_0075

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India