PVX_003805 | serine-repeat antigen (SERA), putative

  • Computed_GO_Component_IDs:        

  • Computed_GO_Components:        

  • Computed_GO_Function_IDs:  GO:0008234      

  • Computed_GO_Functions:  cysteine-type peptidase activity      

  • Computed_GO_Process_IDs:  GO:0006508      

  • Computed_GO_Processes:  proteolysis      

  • Curated_GO_Component_IDs:        

  • Curated_GO_Components:        

  • Curated_GO_Function_IDs:        

  • Curated_GO_Functions:        

  • Curated_GO_Processes:        

_IDPredictionOTHERSPmTPCS_Position
PVX_003805SP0.0174520.9823880.000160CS pos: 22-23. VRC-TG. Pr: 0.7283
No Results

  • Fasta :-

    >PVX_003805 MKARLSLILILCVVCRDCAVRCTGTTEAQGAVEGAKGPKPGAEEAGANVGEAGTGGPGGP GADGGTEAGARAEEGEGAGTEAEPEAEPEAEAEPARGPEPEPEAGGEGINRDAAGNQREG QLEAPSDSARPGAIPQVAPRDTVETSSDAADSSSPDQNPLPGADNTKVGNAATPPEGAKE ETQVKSSLLKGHKGVKVTGPCGASFLVFFAPYLFIDVDTDSSNVYLGTDLSDLEVTEKMG IQDNGKNKCEDKKTFKFVALIGEDHLTIKWKVYDPAVKTPTPNEKVEMRKYVMKNLSGEF TAVQVHTVIQQNGSNVFESKNYALSSGIPEKCDAVATNCFLSGSVYIEKCYRCTLKMKKV DPSDVCYNYIPKVESAASQEAIPAKASDEESSQEELTASIGKILQGVYKKGENGLNEVLT FNEADAALKAELLNYCSLMKKVDASGVLGHYQLGSEEDVHANLTNMLQTNSDHVLSSLQN KLKNPAICLKNADEWVGSKTGLLLPNLFYNHLEGSTPSTSNVTHVDDSSEDVQSGGYDGV IDFATAGKTNFSTSQYADKMHCNAEYCDRAKDAGSCVAKMEVQDQGDCANSWLFASKVHL ETIKCVKGYDHVGASALYVANCSGKEANDKCHSPSNPLEFLNTLEETNFLPADSDLPYSY KQVGNACPEPKGHWQNLWENVKLLGPTNEPNSMSTKGYTAYQSDHFKGNMDSFIKLVKSE VMKKGSVIAYVKVAGALSYDLNGKKVLSLCGSETPDLAVNIVGYGNYISAEGVKKPYWLL QNSWGKHWGDKGTFKVDMNGPPGCHHNFIHTAAVFNLDMPVEENPQKEDAQIYNYYLKSS PDFWGNIYYKNVGGQESASSKNATEGAHESVLHGQEVAEAAVNGAGGEPAPSHSGAVQGE REGTANGQGPEGVPPLPAKQEVTEASNGEATGLGAVNPSGEEQPGPPGPPGTSGLAEQPG PEGPSGEVGSTGSVGQPGQPGSSGTPRSEGQTGPSGTSGSSAAQGQSGSSGTPGSDGPSG HTGPSSTPVQEAPLSKAPGTDSPPVAPEAAVLGSEVTHVLKYIKKNKVKLNLVTYKNHEA LSSGHDCWRSYSANPDKYEECVKLCEANWSKCENDAAPGFCLYEHAKEEDCFFCYV
  • Download Fasta
  • MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/PVX_003805.fa Sequence name : PVX_003805 Sequence length : 1136 VALUES OF COMPUTED PARAMETERS Coef20 : 5.108 CoefTot : 0.898 ChDiff : -56 ZoneTo : 16 KR : 3 DE : 0 CleavSite : 18 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 1.929 1.929 0.347 0.724 MesoH : -0.240 0.228 -0.303 0.194 MuHd_075 : 19.813 13.092 5.794 3.956 MuHd_095 : 16.580 8.569 6.244 3.674 MuHd_100 : 15.663 10.865 6.864 3.348 MuHd_105 : 13.940 11.189 5.980 3.064 Hmax_075 : 19.483 24.150 5.693 6.568 Hmax_095 : 16.900 23.100 6.817 5.900 Hmax_100 : 5.700 17.100 4.399 4.710 Hmax_105 : 7.300 17.500 3.445 5.157 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9238 0.0762 DFMC : 0.8680 0.1320
  • ##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 1136 PVX_003805 MKARLSLILILCVVCRDCAVRCTGTTEAQGAVEGAKGPKPGAEEAGANVGEAGTGGPGGPGADGGTEAGARAEEGEGAGT 80 EAEPEAEPEAEAEPARGPEPEPEAGGEGINRDAAGNQREGQLEAPSDSARPGAIPQVAPRDTVETSSDAADSSSPDQNPL 160 PGADNTKVGNAATPPEGAKEETQVKSSLLKGHKGVKVTGPCGASFLVFFAPYLFIDVDTDSSNVYLGTDLSDLEVTEKMG 240 IQDNGKNKCEDKKTFKFVALIGEDHLTIKWKVYDPAVKTPTPNEKVEMRKYVMKNLSGEFTAVQVHTVIQQNGSNVFESK 320 NYALSSGIPEKCDAVATNCFLSGSVYIEKCYRCTLKMKKVDPSDVCYNYIPKVESAASQEAIPAKASDEESSQEELTASI 400 GKILQGVYKKGENGLNEVLTFNEADAALKAELLNYCSLMKKVDASGVLGHYQLGSEEDVHANLTNMLQTNSDHVLSSLQN 480 KLKNPAICLKNADEWVGSKTGLLLPNLFYNHLEGSTPSTSNVTHVDDSSEDVQSGGYDGVIDFATAGKTNFSTSQYADKM 560 HCNAEYCDRAKDAGSCVAKMEVQDQGDCANSWLFASKVHLETIKCVKGYDHVGASALYVANCSGKEANDKCHSPSNPLEF 640 LNTLEETNFLPADSDLPYSYKQVGNACPEPKGHWQNLWENVKLLGPTNEPNSMSTKGYTAYQSDHFKGNMDSFIKLVKSE 720 VMKKGSVIAYVKVAGALSYDLNGKKVLSLCGSETPDLAVNIVGYGNYISAEGVKKPYWLLQNSWGKHWGDKGTFKVDMNG 800 PPGCHHNFIHTAAVFNLDMPVEENPQKEDAQIYNYYLKSSPDFWGNIYYKNVGGQESASSKNATEGAHESVLHGQEVAEA 880 AVNGAGGEPAPSHSGAVQGEREGTANGQGPEGVPPLPAKQEVTEASNGEATGLGAVNPSGEEQPGPPGPPGTSGLAEQPG 960 PEGPSGEVGSTGSVGQPGQPGSSGTPRSEGQTGPSGTSGSSAAQGQSGSSGTPGSDGPSGHTGPSSTPVQEAPLSKAPGT 1040 DSPPVAPEAAVLGSEVTHVLKYIKKNKVKLNLVTYKNHEALSSGHDCWRSYSANPDKYEECVKLCEANWSKCENDAAPGF 1120 CLYEHAKEEDCFFCYV 1200 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ................................................................................ 480 ................................................................................ 560 ................................................................................ 640 ................................................................................ 720 ................................................................................ 800 ................................................................................ 880 ................................................................................ 960 ................................................................................ 1040 ................................................................................ 1120 ................ 1200 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ PVX_003805 2 -----MK|AR 0.057 . PVX_003805 4 ---MKAR|LS 0.089 . PVX_003805 16 ILCVVCR|DC 0.102 . PVX_003805 21 CRDCAVR|CT 0.140 . PVX_003805 36 GAVEGAK|GP 0.067 . PVX_003805 39 EGAKGPK|PG 0.060 . PVX_003805 71 GTEAGAR|AE 0.102 . PVX_003805 96 AEAEPAR|GP 0.126 . PVX_003805 111 GGEGINR|DA 0.132 . PVX_003805 118 DAAGNQR|EG 0.075 . PVX_003805 130 APSDSAR|PG 0.106 . PVX_003805 140 IPQVAPR|DT 0.120 . PVX_003805 167 PGADNTK|VG 0.063 . PVX_003805 179 TPPEGAK|EE 0.069 . PVX_003805 185 KEETQVK|SS 0.069 . PVX_003805 190 VKSSLLK|GH 0.070 . PVX_003805 193 SLLKGHK|GV 0.077 . PVX_003805 196 KGHKGVK|VT 0.080 . PVX_003805 238 DLEVTEK|MG 0.059 . PVX_003805 246 GIQDNGK|NK 0.062 . PVX_003805 248 QDNGKNK|CE 0.082 . PVX_003805 252 KNKCEDK|KT 0.068 . PVX_003805 253 NKCEDKK|TF 0.083 . PVX_003805 256 EDKKTFK|FV 0.085 . PVX_003805 269 EDHLTIK|WK 0.058 . PVX_003805 271 HLTIKWK|VY 0.086 . PVX_003805 278 VYDPAVK|TP 0.058 . PVX_003805 285 TPTPNEK|VE 0.063 . PVX_003805 289 NEKVEMR|KY 0.086 . PVX_003805 290 EKVEMRK|YV 0.161 . PVX_003805 294 MRKYVMK|NL 0.102 . PVX_003805 320 SNVFESK|NY 0.060 . PVX_003805 331 SSGIPEK|CD 0.070 . PVX_003805 349 GSVYIEK|CY 0.067 . PVX_003805 352 YIEKCYR|CT 0.078 . PVX_003805 356 CYRCTLK|MK 0.061 . PVX_003805 358 RCTLKMK|KV 0.086 . PVX_003805 359 CTLKMKK|VD 0.065 . PVX_003805 372 CYNYIPK|VE 0.061 . PVX_003805 385 QEAIPAK|AS 0.081 . PVX_003805 402 LTASIGK|IL 0.066 . PVX_003805 409 ILQGVYK|KG 0.077 . PVX_003805 410 LQGVYKK|GE 0.090 . PVX_003805 429 EADAALK|AE 0.052 . PVX_003805 440 NYCSLMK|KV 0.078 . PVX_003805 441 YCSLMKK|VD 0.090 . PVX_003805 481 LSSLQNK|LK 0.077 . PVX_003805 483 SLQNKLK|NP 0.072 . PVX_003805 490 NPAICLK|NA 0.078 . PVX_003805 499 DEWVGSK|TG 0.051 . PVX_003805 548 DFATAGK|TN 0.057 . PVX_003805 559 TSQYADK|MH 0.074 . PVX_003805 569 NAEYCDR|AK 0.098 . PVX_003805 571 EYCDRAK|DA 0.093 . PVX_003805 579 AGSCVAK|ME 0.077 . PVX_003805 597 SWLFASK|VH 0.059 . PVX_003805 604 VHLETIK|CV 0.069 . PVX_003805 607 ETIKCVK|GY 0.074 . PVX_003805 625 VANCSGK|EA 0.087 . PVX_003805 630 GKEANDK|CH 0.070 . PVX_003805 661 DLPYSYK|QV 0.089 . PVX_003805 671 NACPEPK|GH 0.075 . PVX_003805 682 NLWENVK|LL 0.062 . PVX_003805 696 PNSMSTK|GY 0.094 . PVX_003805 707 YQSDHFK|GN 0.086 . PVX_003805 715 NMDSFIK|LV 0.063 . PVX_003805 718 SFIKLVK|SE 0.069 . PVX_003805 723 VKSEVMK|KG 0.073 . PVX_003805 724 KSEVMKK|GS 0.103 . PVX_003805 732 SVIAYVK|VA 0.064 . PVX_003805 744 SYDLNGK|KV 0.062 . PVX_003805 745 YDLNGKK|VL 0.079 . PVX_003805 774 ISAEGVK|KP 0.061 . PVX_003805 775 SAEGVKK|PY 0.100 . PVX_003805 786 LQNSWGK|HW 0.096 . PVX_003805 791 GKHWGDK|GT 0.089 . PVX_003805 795 GDKGTFK|VD 0.068 . PVX_003805 827 VEENPQK|ED 0.063 . PVX_003805 838 IYNYYLK|SS 0.075 . PVX_003805 850 WGNIYYK|NV 0.125 . PVX_003805 861 QESASSK|NA 0.090 . PVX_003805 901 GAVQGER|EG 0.081 . PVX_003805 919 VPPLPAK|QE 0.065 . PVX_003805 987 GSSGTPR|SE 0.341 . PVX_003805 1036 QEAPLSK|AP 0.066 . PVX_003805 1061 EVTHVLK|YI 0.061 . PVX_003805 1064 HVLKYIK|KN 0.059 . PVX_003805 1065 VLKYIKK|NK 0.078 . PVX_003805 1067 KYIKKNK|VK 0.058 . PVX_003805 1069 IKKNKVK|LN 0.064 . PVX_003805 1076 LNLVTYK|NH 0.066 . PVX_003805 1089 SGHDCWR|SY 0.175 . PVX_003805 1097 YSANPDK|YE 0.073 . PVX_003805 1103 KYEECVK|LC 0.057 . PVX_003805 1111 CEANWSK|CE 0.067 . PVX_003805 1127 CLYEHAK|EE 0.065 . ____________________________^_________________

  • Fasta :-

    >PVX_003805 ATGAAGGCCCGCCTTTCCTTAATCCTAATTTTATGTGTCGTGTGCAGGGACTGTGCAGTG AGATGCACGGGTACCACTGAAGCTCAAGGAGCAGTAGAAGGAGCAAAGGGACCAAAACCA GGAGCAGAAGAAGCAGGAGCAAATGTAGGAGAGGCAGGAACAGGAGGACCAGGAGGACCA GGAGCAGATGGAGGAACAGAAGCAGGAGCAAGAGCAGAAGAAGGAGAAGGAGCAGGAACA GAAGCAGAACCAGAAGCAGAACCAGAAGCAGAAGCAGAACCAGCACGAGGACCAGAACCA GAACCAGAAGCAGGAGGTGAGGGCATAAATCGGGATGCAGCTGGAAACCAGAGAGAGGGT CAACTTGAAGCCCCATCAGATAGCGCACGTCCAGGAGCAATTCCCCAAGTAGCACCACGA GACACTGTCGAAACTTCTAGCGATGCTGCTGATAGTAGTAGCCCAGACCAGAATCCACTT CCAGGTGCAGACAACACCAAAGTAGGAAATGCAGCAACCCCCCCCGAAGGCGCGAAAGAG GAGACCCAGGTAAAGTCGTCGCTCCTGAAGGGCCACAAGGGGGTGAAGGTGACGGGCCCG TGCGGCGCCAGCTTCCTCGTGTTCTTCGCCCCGTATCTGTTCATCGATGTGGACACGGAC AGTAGCAATGTTTACCTGGGAACTGACTTGAGCGATTTAGAAGTTACAGAAAAAATGGGT ATACAAGATAACGGAAAAAATAAATGCGAAGATAAGAAGACATTCAAATTCGTTGCTCTC ATTGGAGAAGACCACTTGACCATTAAGTGGAAGGTGTACGACCCGGCAGTCAAAACGCCA ACCCCAAATGAAAAAGTGGAAATGAGAAAATACGTAATGAAAAATCTGAGCGGAGAATTC ACCGCTGTGCAAGTGCACACTGTTATACAGCAGAACGGCTCCAACGTCTTTGAAAGCAAA AACTATGCCTTAAGTAGCGGCATCCCTGAAAAATGCGACGCAGTAGCCACCAACTGCTTC CTCAGTGGAAGCGTGTACATAGAGAAATGCTACAGGTGCACCCTCAAAATGAAGAAGGTG GACCCGTCGGACGTTTGCTATAACTATATTCCCAAGGTGGAAAGTGCAGCCAGTCAGGAG GCCATTCCCGCCAAGGCAAGCGATGAAGAGTCCAGCCAAGAGGAGTTGACAGCATCCATT GGAAAGATCCTCCAAGGGGTCTACAAGAAAGGGGAAAATGGTCTCAATGAGGTGCTCACT TTCAACGAAGCAGATGCAGCTTTGAAAGCGGAACTGCTTAACTATTGCTCCTTGATGAAG AAGGTAGACGCCAGTGGGGTGTTGGGCCACTACCAATTGGGAAGTGAAGAAGATGTGCAT GCCAACCTGACGAACATGCTACAGACGAACAGCGACCATGTCTTGTCCTCATTGCAAAAC AAGCTGAAGAATCCCGCCATCTGTTTGAAAAATGCGGACGAGTGGGTGGGTAGCAAAACA GGGCTACTTCTTCCTAATCTGTTTTATAACCATTTGGAAGGGTCCACTCCGTCGACTTCC AACGTGACTCACGTCGACGACTCCTCTGAGGATGTGCAAAGTGGCGGATACGATGGCGTC ATCGATTTCGCCACGGCAGGCAAGACAAATTTCAGCACCTCCCAATACGCAGACAAAATG CACTGCAATGCGGAGTACTGCGATAGGGCGAAGGATGCGGGCAGCTGCGTGGCGAAGATG GAGGTGCAGGACCAGGGCGATTGCGCCAACTCTTGGCTCTTCGCCTCCAAGGTGCACCTA GAGACCATCAAGTGTGTGAAGGGATACGACCACGTCGGTGCATCTGCTCTCTACGTGGCT AACTGTTCCGGTAAAGAAGCGAATGACAAGTGTCACTCACCCTCTAACCCGCTTGAGTTC TTAAACACCCTGGAGGAGACCAACTTTTTGCCAGCCGATTCGGACCTCCCCTATTCGTAC AAGCAAGTGGGAAACGCCTGTCCGGAACCGAAGGGCCACTGGCAAAACCTTTGGGAAAAC GTGAAGCTCCTAGGTCCCACGAATGAGCCCAACTCGATGAGCACCAAGGGGTACACCGCC TACCAGAGCGACCACTTCAAGGGCAACATGGACTCATTTATCAAGTTAGTCAAATCCGAA GTGATGAAAAAGGGATCTGTCATCGCGTATGTGAAGGTGGCGGGAGCACTCAGCTACGAC CTGAACGGAAAGAAGGTCCTCTCTCTATGTGGAAGCGAAACGCCGGACCTTGCTGTCAAC ATAGTGGGCTATGGAAACTACATCAGCGCGGAGGGGGTGAAAAAGCCCTACTGGCTGCTG CAAAACAGCTGGGGTAAACACTGGGGAGACAAGGGAACCTTTAAGGTCGATATGAATGGA CCACCTGGATGCCATCACAACTTCATCCACACCGCCGCCGTCTTCAATCTGGACATGCCC GTGGAGGAGAACCCCCAAAAGGAAGACGCCCAGATATACAACTACTACTTGAAGAGCTCC CCTGATTTTTGGGGCAACATCTACTATAAAAATGTTGGCGGTCAGGAGAGTGCCTCGTCA AAGAACGCAACGGAGGGGGCCCATGAATCGGTGCTGCACGGGCAAGAAGTTGCAGAGGCG GCAGTAAATGGCGCTGGCGGGGAACCTGCTCCTTCACACAGTGGAGCGGTACAAGGAGAA AGAGAAGGAACAGCAAATGGACAAGGACCTGAAGGTGTTCCTCCTTTGCCGGCGAAACAG GAAGTAACCGAAGCATCAAACGGGGAAGCGACAGGACTGGGAGCAGTAAACCCTTCGGGA GAAGAACAGCCAGGACCACCAGGGCCACCAGGGACATCAGGACTAGCAGAGCAACCAGGA CCAGAAGGGCCATCGGGAGAAGTAGGGTCAACAGGATCAGTAGGGCAACCAGGACAACCG GGATCATCGGGCACACCCAGATCGGAAGGACAAACGGGACCATCGGGCACATCAGGATCA TCGGCCGCGCAAGGACAATCGGGTTCATCGGGCACACCCGGATCGGATGGACCATCAGGA CACACGGGACCATCGAGCACACCCGTACAAGAAGCCCCGCTCAGCAAGGCACCCGGAACA GACAGCCCGCCCGTCGCACCCGAAGCCGCCGTGCTAGGCTCCGAAGTGACGCATGTCCTG AAGTACATTAAAAAGAATAAGGTGAAGCTGAACTTGGTGACTTACAAGAATCACGAGGCT CTCAGCTCCGGGCACGACTGCTGGAGATCCTACTCGGCCAACCCGGATAAGTACGAAGAG TGTGTAAAGTTATGCGAAGCCAACTGGAGCAAATGTGAAAATGATGCAGCGCCGGGATTC TGTTTATACGAGCATGCGAAAGAAGAGGACTGTTTCTTCTGCTATGTGTAG
  • Download Fasta

  • Fasta :-

    MKARLSLILILCVVCRDCAVRCTGTTEAQGAVEGAKGPKPGAEEAGANVGEAGTGGPGGP GADGGTEAGARAEEGEGAGTEAEPEAEPEAEAEPARGPEPEPEAGGEGINRDAAGNQREG QLEAPSDSARPGAIPQVAPRDTVETSSDAADSSSPDQNPLPGADNTKVGNAATPPEGAKE ETQVKSSLLKGHKGVKVTGPCGASFLVFFAPYLFIDVDTDSSNVYLGTDLSDLEVTEKMG IQDNGKNKCEDKKTFKFVALIGEDHLTIKWKVYDPAVKTPTPNEKVEMRKYVMKNLSGEF TAVQVHTVIQQNGSNVFESKNYALSSGIPEKCDAVATNCFLSGSVYIEKCYRCTLKMKKV DPSDVCYNYIPKVESAASQEAIPAKASDEESSQEELTASIGKILQGVYKKGENGLNEVLT FNEADAALKAELLNYCSLMKKVDASGVLGHYQLGSEEDVHANLTNMLQTNSDHVLSSLQN KLKNPAICLKNADEWVGSKTGLLLPNLFYNHLEGSTPSTSNVTHVDDSSEDVQSGGYDGV IDFATAGKTNFSTSQYADKMHCNAEYCDRAKDAGSCVAKMEVQDQGDCANSWLFASKVHL ETIKCVKGYDHVGASALYVANCSGKEANDKCHSPSNPLEFLNTLEETNFLPADSDLPYSY KQVGNACPEPKGHWQNLWENVKLLGPTNEPNSMSTKGYTAYQSDHFKGNMDSFIKLVKSE VMKKGSVIAYVKVAGALSYDLNGKKVLSLCGSETPDLAVNIVGYGNYISAEGVKKPYWLL QNSWGKHWGDKGTFKVDMNGPPGCHHNFIHTAAVFNLDMPVEENPQKEDAQIYNYYLKSS PDFWGNIYYKNVGGQESASSKNATEGAHESVLHGQEVAEAAVNGAGGEPAPSHSGAVQGE REGTANGQGPEGVPPLPAKQEVTEASNGEATGLGAVNPSGEEQPGPPGPPGTSGLAEQPG PEGPSGEVGSTGSVGQPGQPGSSGTPRSEGQTGPSGTSGSSAAQGQSGSSGTPGSDGPSG HTGPSSTPVQEAPLSKAPGTDSPPVAPEAAVLGSEVTHVLKYIKKNKVKLNLVTYKNHEA LSSGHDCWRSYSANPDKYEECVKLCEANWSKCENDAAPGFCLYEHAKEEDCFFCYV

  • title: active site
  • coordinates: Q585,S591,L757,N782
IDSitePositionGscoreIscore
PVX_003805T1420.5050.058
IDSitePositionGscoreIscore
PVX_003805T1420.5050.058
IDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethodIDSitePeptideScoreMethod
PVX_003805528 SHVDDSSEDV0.997unspPVX_003805528 SHVDDSSEDV0.997unspPVX_003805528 SHVDDSSEDV0.997unspPVX_003805554 SNFSTSQYAD0.992unspPVX_003805859 SQESASSKNA0.995unspPVX_003805939 SAVNPSGEEQ0.996unspPVX_003805387 SPAKASDEES0.996unspPVX_003805392 SDEESSQEEL0.997unsp
PVX_003805      


Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India