SPBC13E7.11 | mitochondrial rhomboid protease (predicted)

UniProt_ID: O14364

Computed_GO_Component_IDs: GO:0016021
Computed_GO_Components: integral component of membrane
Computed_GO_Function_IDs: GO:0004252
Computed_GO_Functions: serine-type endopeptidase activity
Computed_GO_Process_IDs:
Computed_GO_Processes:
Curated_GO_Component_IDs: GO:0005743 GO:0005739
Curated_GO_Components: mitochondrial inner membrane mitochondrion
Curated_GO_Function_IDs: GO:0004252
Curated_GO_Functions: serine-type endopeptidase activity
Curated_GO_Processes: mitochondrion organization regulation of mitochondrion organization signal peptide processing

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	SPBC13E7.11	OTHER	0.902518	0.000111	0.097371

No Results

Fasta :-
>SPBC13E7.11 MNRLNFQSLLWKFGQKRFYYRPWIRIENIKPTPLWKPITFAVGVGSATFYTANYLDKRRK NYPKSSYGFPIPQTSSRSLVLSIIGINVGVFALWRAPRFSHLNRFLQKYAVMNPIFINMP SMIVSAFSHQSGWHLLFNMVAFYSFAPAIVDVFGNNQFVAFYISSILFSNVASLLHHRLR FGTKVTPGSLGASGAIYAIAAATSYFFPNASVSIIFLPFIPIKIGVALLGLMAFDAWGLI SRGFSSFANFTLIDHAAHLGGGIFGWLYAKYGYSTYNRSTRPRPPSLSKPFFSRSVSF
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/446 Sequence name : 446 Sequence length : 298 VALUES OF COMPUTED PARAMETERS Coef20 : 4.091 CoefTot : -6.983 ChDiff : 24 ZoneTo : 295 KR : 29 DE : 5 CleavSite : 296 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 1.829 2.212 0.293 0.831 MesoH : 1.105 1.199 0.063 0.556 MuHd_075 : 50.303 32.806 13.217 11.889 MuHd_095 : 33.678 24.277 9.352 7.719 MuHd_100 : 35.475 25.916 10.054 8.412 MuHd_105 : 39.369 26.694 9.985 9.376 Hmax_075 : 15.500 24.383 4.237 6.450 Hmax_095 : 7.900 20.913 3.033 4.900 Hmax_100 : 18.100 21.800 2.738 6.470 Hmax_105 : 18.300 17.100 2.696 6.250 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.0109 0.9891 DFMC : 0.0002 0.9998 This protein is probably imported in mitochondria. f(Ser) = 0.1085 f(Arg) = 0.0576 CMi = 0.71991 CMi is the Chloroplast/Mitochondria Index It has been proposed by Von Heijne et al (Eur J Biochem,1989, 180: 535-545)

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 298 SPBC13E7.11 MNRLNFQSLLWKFGQKRFYYRPWIRIENIKPTPLWKPITFAVGVGSATFYTANYLDKRRKNYPKSSYGFPIPQTSSRSLV 80 LSIIGINVGVFALWRAPRFSHLNRFLQKYAVMNPIFINMPSMIVSAFSHQSGWHLLFNMVAFYSFAPAIVDVFGNNQFVA 160 FYISSILFSNVASLLHHRLRFGTKVTPGSLGASGAIYAIAAATSYFFPNASVSIIFLPFIPIKIGVALLGLMAFDAWGLI 240 SRGFSSFANFTLIDHAAHLGGGIFGWLYAKYGYSTYNRSTRPRPPSLSKPFFSRSVSF 320 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 .......................................................... 320 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ SPBC13E7.11 3 ----MNR|LN 0.097 . SPBC13E7.11 12 FQSLLWK|FG 0.064 . SPBC13E7.11 16 LWKFGQK|RF 0.054 . SPBC13E7.11 17 WKFGQKR|FY 0.153 . SPBC13E7.11 21 QKRFYYR|PW 0.140 . SPBC13E7.11 25 YYRPWIR|IE 0.078 . SPBC13E7.11 30 IRIENIK|PT 0.065 . SPBC13E7.11 36 KPTPLWK|PI 0.068 . SPBC13E7.11 57 TANYLDK|RR 0.064 . SPBC13E7.11 58 ANYLDKR|RK 0.104 . SPBC13E7.11 59 NYLDKRR|KN 0.102 . SPBC13E7.11 60 YLDKRRK|NY 0.078 . SPBC13E7.11 64 RRKNYPK|SS 0.091 . SPBC13E7.11 77 IPQTSSR|SL 0.154 . SPBC13E7.11 95 GVFALWR|AP 0.070 . SPBC13E7.11 98 ALWRAPR|FS 0.303 . SPBC13E7.11 104 RFSHLNR|FL 0.152 . SPBC13E7.11 108 LNRFLQK|YA 0.075 . SPBC13E7.11 178 ASLLHHR|LR 0.073 . SPBC13E7.11 180 LLHHRLR|FG 0.143 . SPBC13E7.11 184 RLRFGTK|VT 0.071 . SPBC13E7.11 223 LPFIPIK|IG 0.065 . SPBC13E7.11 242 AWGLISR|GF 0.085 . SPBC13E7.11 270 FGWLYAK|YG 0.058 . SPBC13E7.11 278 GYSTYNR|ST 0.169 . SPBC13E7.11 281 TYNRSTR|PR 0.271 . SPBC13E7.11 283 NRSTRPR|PP 0.132 . SPBC13E7.11 289 RPPSLSK|PF 0.060 . SPBC13E7.11 294 SKPFFSR|SV 0.267 . ____________________________^_________________

Fasta :-
>SPBC13E7.11 GTTTGGCATATATATTTATATAAGATTATGCAAGTAACGTAATTAGGAGAATAAAAAGTA AGACAGAATATATAAAGAAATAACTTAAATTGCTTGAAGTTAAATAAATATTGGTAAAGA TCTTAAGGTACTGTGAGAAGCGTAAGCGGATTCTTATTTCTCTATCTTAGGCAACACTAG CGTTTCTATGCATACAACCTCATAGTCCTTACTCACCTTTTCTCACATATATTTAATACG CAGATGAATCGTTTGAATTTTCAAAGTTTACTCTGGAAATTTGGACAAAAAAGGTTTTAT TACAGACCATGGATCAGAATTGAAAATATTAAACCAACACCATTATGGAAACCGATTACA TTTGCTGTTGGTGTTGGTTCTGCCACCTTTTATACGGCCAATTATCTCGATAAAAGAAGA AAAAACTACCCCAAAAGCTCATACGGATTTCCAATTCCCCAAACATCTAGTCGAAGTTTG GTATTGTCGATAATTGGAATCAACGTCGGTGTGTTTGCGTTATGGCGAGCTCCGAGGTTT AGTCATTTAAATAGATTTTTACAAAAATATGCTGTCATGAACCCTATATTTATTAATATG CCATCGATGATCGTATCCGCATTCAGCCATCAATCTGGATGGCATTTGCTATTCAACATG GTTGCCTTTTACTCCTTTGCGCCTGCAATTGTTGACGTTTTTGGAAATAATCAGTTTGTT GCATTTTATATTTCTTCGATTCTTTTTTCTAACGTTGCTTCTCTCTTGCACCATCGTTTG CGCTTTGGGACTAAAGTTACTCCAGGATCATTAGGTGCTAGTGGTGCAATCTATGCTATT GCTGCTGCTACATCTTATTTCTTCCCAAATGCTTCTGTCTCCATTATTTTCCTTCCCTTT ATACCTATTAAAATTGGAGTTGCGCTATTAGGCCTCATGGCCTTTGATGCTTGGGGATTA ATTTCTCGAGGGTTTTCCTCCTTTGCAAACTTTACACTCATTGACCACGCTGCACATCTT GGAGGTGGAATATTCGGTTGGTTGTATGCTAAATATGGCTATTCTACGTACAACCGATCG ACTCGTCCCCGTCCACCGTCGTTGAGTAAACCATTTTTTTCAAGATCCGTTTCCTTTTGA GCTATGTTTTAAAAAATTCAAACACTACAATTTTCAACATGAATTTGCATTTTGGATTTC ATTATTTTATTAAATGTTTTCTCTAAATCTGTAGTATGAACCAAACCCTTCAGGTGAGGA ATAACAGGCATCTGCTTGAATTGATTGTTTTAAGCAGCCATCAATAGGGCAGAATTCTTT TTTGATATAAATCCCAAAGACGTATAGCT
Download Fasta

Fasta :-

MNRLNFQSLLWKFGQKRFYYRPWIRIENIKPTPLWKPITFAVGVGSATFYTANYLDKRRK NYPKSSYGFPIPQTSSRSLVLSIIGINVGVFALWRAPRFSHLNRFLQKYAVMNPIFINMP SMIVSAFSHQSGWHLLFNMVAFYSFAPAIVDVFGNNQFVAFYISSILFSNVASLLHHRLR FGTKVTPGSLGASGAIYAIAAATSYFFPNASVSIIFLPFIPIKIGVALLGLMAFDAWGLI SRGFSSFANFTLIDHAAHLGGGIFGWLYAKYGYSTYNRSTRPRPPSLSKPFFSRSVSF

Rhomboid-like

No Results

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	SPBC13E7.11	S	297	0.574	0.033	SPBC13E7.11	S	295	0.560	0.025	SPBC13E7.11	S	293	0.552	0.079

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	SPBC13E7.11	S	297	0.574	0.033	SPBC13E7.11	S	295	0.560	0.025	SPBC13E7.11	S	293	0.552	0.079

	ID	Site	Peptide	Score	Method
	SPBC13E7.11	286 S	PRPPSLSKP	0.993	unsp

SPBC13E7.11 | mitochondrial rhomboid protease (predicted)

ID's

UniProt_ID: O14364

GEO Functions

Computed_GO_Component_IDs: GO:0016021

Computed_GO_Components: integral component of membrane

Computed_GO_Function_IDs: GO:0004252

Computed_GO_Functions: serine-type endopeptidase activity

Computed_GO_Process_IDs:

Computed_GO_Processes:

Curated_GO_Component_IDs: GO:0005743 GO:0005739

Curated_GO_Components: mitochondrial inner membrane mitochondrion

Curated_GO_Function_IDs: GO:0004252

Curated_GO_Functions: serine-type endopeptidase activity

Curated_GO_Processes: mitochondrion organization regulation of mitochondrion organization signal peptide processing

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Rhomboid-like

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

SPBC30D10.19c

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India