TA15665 | cathepsin-like cysteine protease, putative

UniProt_ID: Q4UFL9

Computed_GO_Component_IDs:
Computed_GO_Components:
Computed_GO_Function_IDs: GO:0008234
Computed_GO_Functions: cysteine-type peptidase activity
Computed_GO_Process_IDs: GO:0006508
Computed_GO_Processes: proteolysis
Curated_GO_Component_IDs:
Curated_GO_Components:
Curated_GO_Function_IDs:
Curated_GO_Functions:
Curated_GO_Processes:

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	TA15665	SP	0.043990	0.955726	0.000284	CS pos: 24-25. VKL-DL. Pr: 0.4266

No Results

Fasta :-
>TA15665 MLFKVCKLKYFILLFIIIISHVKLDLPIHTLTKDVIGIWKIYETELYDKFQNCGSTYPNK NIENLKIDNFKEYLQEIYGELYVKFIELSDERFFNRTLLYPRNTWSYFTIKNPLNNQILG HWTLVYDEGVMIDINDKNYFGYFKYNNIKNNECKQITQNIEDEYGNIKCYVTDSNRLQIG WYSKKINNNYKFGCFYMEKLKYNNNKNYIIDLTFNTTHNELEFSTPTEFSTPSQFSPNFP PTNPNSPNNKINTLNSLINPINPISTNWKNNINNPIDPINMIWKNKLGIGYENISPLRFI QLCKGVNYQVINNFNTSVTVTGPPNSSNRTNGTSTEDTTGASTVTEGNSTIQIAAPKVGT STTNTLGKGANSTLMECTTTNNTIEEKNINTIAVVTKTGESGTNSNTHTDTTGKGVNDTF NSPGKGANYTFDTTGKGANSTAMECISEKNLNEIAVVTKTRESSNNSKDVTNDIKHTEDG EEVVTKGPLRTVGTKAVGMVGPSGSVGTACRGPVTVTEKSFPNNWTWGDPFNGLEEDIYT TSQGECGSCYIYSSLYVISKRYQILFKKLYPNYNWKLKQFQLSINDILTSPYSQGCYGGF LMLVGKHIKEFGIHSDNRIEQNNQIEQIEQIEQIEQFNDQNDNKWYIENYGYVGGCYECT NEINMMNEIITNGPIAVAIYSPIQLFYYTNGIFNNNYKHGIICDLPYNNLNGWEYTNHAI IIVGWGIEIINDEEIKYWICKNTWGKNWGIEGYFKIKKGINLCGIESQAVYFDPTLIKGL SKKLIQIYNKIK
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/TA15665.fa Sequence name : TA15665 Sequence length : 792 VALUES OF COMPUTED PARAMETERS Coef20 : 4.731 CoefTot : -0.126 ChDiff : -5 ZoneTo : 24 KR : 4 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 1.194 2.129 0.137 0.720 MesoH : -0.289 0.210 -0.309 0.325 MuHd_075 : 17.568 12.822 5.792 3.982 MuHd_095 : 10.075 8.754 4.420 2.681 MuHd_100 : 15.092 16.596 5.002 4.703 MuHd_105 : 18.717 19.088 7.109 5.339 Hmax_075 : 17.150 20.825 3.882 6.300 Hmax_095 : 20.100 23.500 4.951 7.520 Hmax_100 : 22.100 28.500 1.977 8.800 Hmax_105 : 22.167 27.387 5.465 8.662 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9572 0.0428 DFMC : 0.9661 0.0339

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 792 TA15665 MLFKVCKLKYFILLFIIIISHVKLDLPIHTLTKDVIGIWKIYETELYDKFQNCGSTYPNKNIENLKIDNFKEYLQEIYGE 80 LYVKFIELSDERFFNRTLLYPRNTWSYFTIKNPLNNQILGHWTLVYDEGVMIDINDKNYFGYFKYNNIKNNECKQITQNI 160 EDEYGNIKCYVTDSNRLQIGWYSKKINNNYKFGCFYMEKLKYNNNKNYIIDLTFNTTHNELEFSTPTEFSTPSQFSPNFP 240 PTNPNSPNNKINTLNSLINPINPISTNWKNNINNPIDPINMIWKNKLGIGYENISPLRFIQLCKGVNYQVINNFNTSVTV 320 TGPPNSSNRTNGTSTEDTTGASTVTEGNSTIQIAAPKVGTSTTNTLGKGANSTLMECTTTNNTIEEKNINTIAVVTKTGE 400 SGTNSNTHTDTTGKGVNDTFNSPGKGANYTFDTTGKGANSTAMECISEKNLNEIAVVTKTRESSNNSKDVTNDIKHTEDG 480 EEVVTKGPLRTVGTKAVGMVGPSGSVGTACRGPVTVTEKSFPNNWTWGDPFNGLEEDIYTTSQGECGSCYIYSSLYVISK 560 RYQILFKKLYPNYNWKLKQFQLSINDILTSPYSQGCYGGFLMLVGKHIKEFGIHSDNRIEQNNQIEQIEQIEQIEQFNDQ 640 NDNKWYIENYGYVGGCYECTNEINMMNEIITNGPIAVAIYSPIQLFYYTNGIFNNNYKHGIICDLPYNNLNGWEYTNHAI 720 IIVGWGIEIINDEEIKYWICKNTWGKNWGIEGYFKIKKGINLCGIESQAVYFDPTLIKGLSKKLIQIYNKIK 800 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ................................................................................ 480 ................................................................................ 560 ................................................................................ 640 ................................................................................ 720 ........................................................................ 800 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ TA15665 4 ---MLFK|VC 0.054 . TA15665 7 MLFKVCK|LK 0.066 . TA15665 9 FKVCKLK|YF 0.064 . TA15665 23 IIISHVK|LD 0.056 . TA15665 33 PIHTLTK|DV 0.090 . TA15665 40 DVIGIWK|IY 0.066 . TA15665 49 ETELYDK|FQ 0.058 . TA15665 60 GSTYPNK|NI 0.066 . TA15665 66 KNIENLK|ID 0.061 . TA15665 71 LKIDNFK|EY 0.071 . TA15665 84 YGELYVK|FI 0.067 . TA15665 92 IELSDER|FF 0.073 . TA15665 96 DERFFNR|TL 0.086 . TA15665 102 RTLLYPR|NT 0.079 . TA15665 111 WSYFTIK|NP 0.058 . TA15665 137 MIDINDK|NY 0.058 . TA15665 144 NYFGYFK|YN 0.062 . TA15665 149 FKYNNIK|NN 0.071 . TA15665 154 IKNNECK|QI 0.098 . TA15665 168 DEYGNIK|CY 0.054 . TA15665 176 YVTDSNR|LQ 0.062 . TA15665 184 QIGWYSK|KI 0.061 . TA15665 185 IGWYSKK|IN 0.092 . TA15665 191 KINNNYK|FG 0.070 . TA15665 199 GCFYMEK|LK 0.059 . TA15665 201 FYMEKLK|YN 0.061 . TA15665 206 LKYNNNK|NY 0.075 . TA15665 250 PNSPNNK|IN 0.060 . TA15665 269 PISTNWK|NN 0.066 . TA15665 284 PINMIWK|NK 0.063 . TA15665 286 NMIWKNK|LG 0.069 . TA15665 298 ENISPLR|FI 0.081 . TA15665 304 RFIQLCK|GV 0.077 . TA15665 329 PPNSSNR|TN 0.149 . TA15665 357 IQIAAPK|VG 0.060 . TA15665 368 TTNTLGK|GA 0.087 . TA15665 387 NNTIEEK|NI 0.064 . TA15665 397 TIAVVTK|TG 0.080 . TA15665 414 HTDTTGK|GV 0.088 . TA15665 425 TFNSPGK|GA 0.091 . TA15665 436 TFDTTGK|GA 0.067 . TA15665 449 MECISEK|NL 0.064 . TA15665 459 EIAVVTK|TR 0.068 . TA15665 461 AVVTKTR|ES 0.094 . TA15665 468 ESSNNSK|DV 0.107 . TA15665 475 DVTNDIK|HT 0.079 . TA15665 486 GEEVVTK|GP 0.071 . TA15665 490 VTKGPLR|TV 0.138 . TA15665 495 LRTVGTK|AV 0.118 . TA15665 511 SVGTACR|GP 0.086 . TA15665 519 PVTVTEK|SF 0.068 . TA15665 560 SLYVISK|RY 0.061 . TA15665 561 LYVISKR|YQ 0.121 . TA15665 567 RYQILFK|KL 0.068 . TA15665 568 YQILFKK|LY 0.073 . TA15665 576 YPNYNWK|LK 0.068 . TA15665 578 NYNWKLK|QF 0.069 . TA15665 606 FLMLVGK|HI 0.070 . TA15665 609 LVGKHIK|EF 0.068 . TA15665 618 GIHSDNR|IE 0.084 . TA15665 644 NDQNDNK|WY 0.065 . TA15665 698 IFNNNYK|HG 0.062 . TA15665 736 INDEEIK|YW 0.069 . TA15665 741 IKYWICK|NT 0.074 . TA15665 746 CKNTWGK|NW 0.083 . TA15665 755 GIEGYFK|IK 0.059 . TA15665 757 EGYFKIK|KG 0.058 . TA15665 758 GYFKIKK|GI 0.098 . TA15665 778 FDPTLIK|GL 0.078 . TA15665 782 LIKGLSK|KL 0.068 . TA15665 783 IKGLSKK|LI 0.111 . TA15665 790 LIQIYNK|IK 0.062 . TA15665 792 QIYNKIK|-- 0.070 . ____________________________^_________________

Fasta :-
>TA15665 ATGTTATTTAAAGTGTGTAAATTAAAATATTTTATTTTATTATTTATAATAATAATATCA CATGTTAAATTAGATTTACCAATACATACATTAACAAAAGATGTAATTGGTATATGGAAA ATATATGAAACAGAATTATATGATAAATTTCAAAATTGTGGTAGTACATATCCTAATAAA AATATAGAAAATTTGAAAATTGATAATTTTAAAGAATATTTACAAGAAATTTATGGTGAA TTATATGTTAAATTTATTGAATTATCTGATGAACGATTTTTTAATAGAACATTATTATAT CCAAGAAATACTTGGTCTTATTTTACTATTAAAAATCCATTAAATAATCAAATTCTAGGC CATTGGACATTAGTATATGATGAAGGTGTAATGATAGATATAAATGATAAAAATTATTTT GGTTATTTTAAATATAATAATATTAAAAATAATGAATGTAAACAAATTACACAAAATATT GAAGATGAATATGGTAATATAAAATGTTATGTAACAGATTCAAATAGATTACAAATAGGT TGGTATAGTAAAAAAATTAATAATAATTATAAATTTGGTTGTTTTTATATGGAAAAATTA AAATATAATAATAATAAAAATTATATTATTGATTTAACTTTTAATACAACACATAATGAA TTGGAATTTTCTACACCTACAGAATTTTCAACACCTTCACAATTTTCTCCTAATTTTCCT CCAACTAATCCAAATTCACCAAATAATAAAATTAATACTCTAAATTCACTAATTAATCCA ATTAATCCAATTAGTACTAATTGGAAGAATAATATAAATAATCCAATTGATCCAATTAAT ATGATTTGGAAGAATAAATTGGGAATTGGATATGAAAATATATCACCATTAAGATTTATA CAATTATGTAAAGGTGTAAATTATCAAGTAATAAATAATTTTAATACTTCCGTTACGGTG ACTGGTCCACCAAACAGTTCTAACCGTACCAACGGTACCAGTACTGAGGATACTACTGGA GCAAGCACCGTTACGGAAGGAAATTCTACTATCCAAATTGCTGCTCCTAAAGTAGGTACT TCAACTACCAATACCCTGGGAAAGGGAGCTAATTCTACCCTTATGGAGTGTACTACTACT AATAATACTATTGAGGAGAAAAATATTAATACTATTGCTGTTGTAACTAAAACTGGGGAG TCAGGTACTAATTCTAATACCCATACCGATACCACTGGAAAGGGAGTTAATGACACTTTT AATAGTCCGGGAAAGGGAGCTAATTACACTTTTGATACTACTGGAAAGGGAGCTAATTCT ACAGCCATGGAGTGTATTAGTGAGAAAAATTTGAATGAAATTGCTGTTGTAACTAAAACC AGGGAGTCAAGTAATAATTCTAAGGATGTTACTAATGATATTAAGCATACTGAGGATGGT GAGGAAGTTGTTACTAAGGGACCCTTACGGACTGTTGGTACTAAGGCAGTTGGTATGGTA GGCCCTTCGGGATCTGTTGGTACTGCTTGTCGTGGACCAGTCACCGTTACGGAAAAAAGT TTCCCAAATAATTGGACTTGGGGTGATCCATTTAATGGTCTTGAAGAAGATATATATACC ACAAGTCAAGGAGAATGTGGTAGTTGTTATATATATAGTTCATTATATGTAATAAGTAAA AGATATCAAATATTATTTAAAAAATTATATCCAAATTATAATTGGAAATTAAAACAATTT CAATTATCAATTAATGATATATTAACATCCCCATATTCACAAGGTTGTTATGGTGGTTTC TTAATGCTTGTTGGTAAACATATTAAAGAATTCGGTATCCACTCAGATAACCGAATTGAA CAAAATAATCAAATAGAACAAATTGAACAAATTGAACAAATAGAACAATTTAATGATCAG AATGATAATAAATGGTATATTGAGAATTATGGATATGTTGGTGGTTGTTATGAATGTACA AATGAAATAAATATGATGAATGAAATAATAACAAATGGTCCAATAGCAGTAGCAATTTAT TCACCAATACAATTATTTTATTATACAAATGGTATATTTAATAATAATTATAAACATGGT ATTATATGTGATTTACCATATAATAATCTTAATGGATGGGAATATACAAATCATGCTATA ATAATAGTTGGTTGGGGTATAGAAATAATAAATGATGAAGAAATAAAATATTGGATATGT AAAAATACTTGGGGTAAAAATTGGGGTATAGAAGGATATTTTAAAATAAAAAAAGGTATA AATTTATGTGGTATAGAAAGTCAAGCTGTTTATTTTGATCCAACATTAATAAAAGGTTTA TCAAAAAAATTAATACAAATTTATAATAAAATAAAATAA
Download Fasta

Fasta :-

MLFKVCKLKYFILLFIIIISHVKLDLPIHTLTKDVIGIWKIYETELYDKFQNCGSTYPNK NIENLKIDNFKEYLQEIYGELYVKFIELSDERFFNRTLLYPRNTWSYFTIKNPLNNQILG HWTLVYDEGVMIDINDKNYFGYFKYNNIKNNECKQITQNIEDEYGNIKCYVTDSNRLQIG WYSKKINNNYKFGCFYMEKLKYNNNKNYIIDLTFNTTHNELEFSTPTEFSTPSQFSPNFP PTNPNSPNNKINTLNSLINPINPISTNWKNNINNPIDPINMIWKNKLGIGYENISPLRFI QLCKGVNYQVINNFNTSVTVTGPPNSSNRTNGTSTEDTTGASTVTEGNSTIQIAAPKVGT STTNTLGKGANSTLMECTTTNNTIEEKNINTIAVVTKTGESGTNSNTHTDTTGKGVNDTF NSPGKGANYTFDTTGKGANSTAMECISEKNLNEIAVVTKTRESSNNSKDVTNDIKHTEDG EEVVTKGPLRTVGTKAVGMVGPSGSVGTACRGPVTVTEKSFPNNWTWGDPFNGLEEDIYT TSQGECGSCYIYSSLYVISKRYQILFKKLYPNYNWKLKQFQLSINDILTSPYSQGCYGGF LMLVGKHIKEFGIHSDNRIEQNNQIEQIEQIEQIEQFNDQNDNKWYIENYGYVGGCYECT NEINMMNEIITNGPIAVAIYSPIQLFYYTNGIFNNNYKHGIICDLPYNNLNGWEYTNHAI IIVGWGIEIINDEEIKYWICKNTWGKNWGIEGYFKIKKGINLCGIESQAVYFDPTLIKGL SKKLIQIYNKIK

Dipeptidyl peptidase I (cathepsin C), exclusion domain

title: active site
coordinates: Q543,C549,H718,N742

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	TA15665	T	330	0.616	0.058	TA15665	T	335	0.596	0.071	TA15665	T	333	0.587	0.185	TA15665	T	231	0.560	0.055	TA15665	T	338	0.547	0.051	TA15665	T	339	0.507	0.030	TA15665	T	350	0.507	0.043	TA15665	T	345	0.505	0.092	TA15665	T	227	0.500	0.030

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	TA15665	T	330	0.616	0.058	TA15665	T	335	0.596	0.071	TA15665	T	333	0.587	0.185	TA15665	T	231	0.560	0.055	TA15665	T	338	0.547	0.051	TA15665	T	339	0.507	0.030	TA15665	T	350	0.507	0.043	TA15665	T	345	0.505	0.092	TA15665	T	227	0.500	0.030

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	TA15665	334 S	TNGTSTEDT	0.998	unsp	TA15665	463 S	KTRESSNNS	0.997	unsp

TA15665 | cathepsin-like cysteine protease, putative

ID's

UniProt_ID: Q4UFL9

GEO Functions

Computed_GO_Component_IDs:

Computed_GO_Components:

Computed_GO_Function_IDs: GO:0008234

Computed_GO_Functions: cysteine-type peptidase activity

Computed_GO_Process_IDs: GO:0006508

Computed_GO_Processes: proteolysis

Curated_GO_Component_IDs:

Curated_GO_Components:

Curated_GO_Function_IDs:

Curated_GO_Functions:

Curated_GO_Processes:

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Dipeptidyl peptidase I (cathepsin C), exclusion domain

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

TA15665

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India