YBL091C | methionine aminopeptidase

UniProt_ID: P38174

Computed_GO_Component_IDs: GO:0005737
Computed_GO_Components: cytoplasm
Computed_GO_Function_IDs: GO:0004177 GO:0016787 GO:0046872 GO:0070006 GO:0008235 GO:0008233
Computed_GO_Functions: aminopeptidase activity hydrolase activity metal ion binding metalloaminopeptidase activity metalloexopeptidase activity peptidase activity
Computed_GO_Process_IDs: GO:0070084 GO:0006508
Computed_GO_Processes: protein initiator methionine removal proteolysis
Curated_GO_Component_IDs: GO:0005737 GO:0005634
Curated_GO_Components: cytoplasm nucleus
Curated_GO_Function_IDs: GO:0070006
Curated_GO_Functions: metalloaminopeptidase activity
Curated_GO_Processes: protein initiator methionine removal involved in protein maturation

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YBL091C	OTHER	0.999994	0.000002	0.000005

No Results

Fasta :-
>YBL091C MTDAEIENSPASDLKELNLENEGVEQQDQAKADESDPVESKKKKNKKKKKKKSNVKKIEL LFPDGKYPEGAWMDYHQDFNLQRTTDEESRYLKRDLERAEHWNDVRKGAEIHRRVRRAIK DRIVPGMKLMDIADMIENTTRKYTGAENLLAMEDPKSQGIGFPTGLSLNHCAAHFTPNAG DKTVLKYEDVMKVDYGVQVNGNIIDSAFTVSFDPQYDNLLAAVKDATYTGIKEAGIDVRL TDIGEAIQEVMESYEVEINGETYQVKPCRNLCGHSIAPYRIHGGKSVPIVKNGDTTKMEE GEHFAIETFGSTGRGYVTAGGEVSHYARSAEDHQVMPTLDSAKNLLKTIDRNFGTLPFCR RYLDRLGQEKYLFALNNLVRHGLVQDYPPLNDIPGSYTAQFEHTILLHAHKKEVVSKGDD Y
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YBL091C.fa Sequence name : YBL091C Sequence length : 421 VALUES OF COMPUTED PARAMETERS Coef20 : 3.185 CoefTot : 0.000 ChDiff : -10 ZoneTo : 2 KR : 0 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 0.900 0.700 -0.066 0.428 MesoH : -0.833 0.033 -0.482 0.173 MuHd_075 : 14.279 8.853 3.279 2.483 MuHd_095 : 13.974 10.052 4.585 3.536 MuHd_100 : 5.858 9.300 3.832 3.226 MuHd_105 : 9.226 11.348 3.443 3.726 Hmax_075 : -3.237 3.063 -2.703 1.794 Hmax_095 : -3.237 1.750 -2.386 1.619 Hmax_100 : -8.700 2.800 -2.923 1.870 Hmax_105 : -0.800 6.100 -2.514 2.560 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9324 0.0676 DFMC : 0.9166 0.0834

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 421 YBL091C MTDAEIENSPASDLKELNLENEGVEQQDQAKADESDPVESKKKKNKKKKKKKSNVKKIELLFPDGKYPEGAWMDYHQDFN 80 LQRTTDEESRYLKRDLERAEHWNDVRKGAEIHRRVRRAIKDRIVPGMKLMDIADMIENTTRKYTGAENLLAMEDPKSQGI 160 GFPTGLSLNHCAAHFTPNAGDKTVLKYEDVMKVDYGVQVNGNIIDSAFTVSFDPQYDNLLAAVKDATYTGIKEAGIDVRL 240 TDIGEAIQEVMESYEVEINGETYQVKPCRNLCGHSIAPYRIHGGKSVPIVKNGDTTKMEEGEHFAIETFGSTGRGYVTAG 320 GEVSHYARSAEDHQVMPTLDSAKNLLKTIDRNFGTLPFCRRYLDRLGQEKYLFALNNLVRHGLVQDYPPLNDIPGSYTAQ 400 FEHTILLHAHKKEVVSKGDDY 480 ................................................................................ 80 ....................................P........................................... 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ..................... 480 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 1 Name Pos Context Score Pred ____________________________v_________________ YBL091C 15 SPASDLK|EL 0.068 . YBL091C 31 EQQDQAK|AD 0.070 . YBL091C 41 SDPVESK|KK 0.057 . YBL091C 42 DPVESKK|KK 0.103 . YBL091C 43 PVESKKK|KN 0.089 . YBL091C 44 VESKKKK|NK 0.143 . YBL091C 46 SKKKKNK|KK 0.075 . YBL091C 47 KKKKNKK|KK 0.115 . YBL091C 48 KKKNKKK|KK 0.137 . YBL091C 49 KKNKKKK|KK 0.144 . YBL091C 50 KNKKKKK|KK 0.161 . YBL091C 51 NKKKKKK|KS 0.120 . YBL091C 52 KKKKKKK|SN 0.256 . YBL091C 56 KKKSNVK|KI 0.070 . YBL091C 57 KKSNVKK|IE 0.119 . YBL091C 66 LLFPDGK|YP 0.070 . YBL091C 83 QDFNLQR|TT 0.094 . YBL091C 90 TTDEESR|YL 0.083 . YBL091C 93 EESRYLK|RD 0.096 . YBL091C 94 ESRYLKR|DL 0.422 . YBL091C 98 LKRDLER|AE 0.088 . YBL091C 106 EHWNDVR|KG 0.070 . YBL091C 107 HWNDVRK|GA 0.162 . YBL091C 113 KGAEIHR|RV 0.115 . YBL091C 114 GAEIHRR|VR 0.141 . YBL091C 116 EIHRRVR|RA 0.269 . YBL091C 117 IHRRVRR|AI 0.604 *ProP* YBL091C 120 RVRRAIK|DR 0.139 . YBL091C 122 RRAIKDR|IV 0.174 . YBL091C 128 RIVPGMK|LM 0.062 . YBL091C 141 MIENTTR|KY 0.105 . YBL091C 142 IENTTRK|YT 0.132 . YBL091C 156 LAMEDPK|SQ 0.119 . YBL091C 182 TPNAGDK|TV 0.119 . YBL091C 186 GDKTVLK|YE 0.066 . YBL091C 192 KYEDVMK|VD 0.066 . YBL091C 224 NLLAAVK|DA 0.066 . YBL091C 232 ATYTGIK|EA 0.065 . YBL091C 239 EAGIDVR|LT 0.116 . YBL091C 266 GETYQVK|PC 0.062 . YBL091C 269 YQVKPCR|NL 0.093 . YBL091C 280 HSIAPYR|IH 0.096 . YBL091C 285 YRIHGGK|SV 0.127 . YBL091C 291 KSVPIVK|NG 0.060 . YBL091C 297 KNGDTTK|ME 0.073 . YBL091C 314 TFGSTGR|GY 0.105 . YBL091C 328 EVSHYAR|SA 0.377 . YBL091C 343 PTLDSAK|NL 0.059 . YBL091C 347 SAKNLLK|TI 0.073 . YBL091C 351 LLKTIDR|NF 0.090 . YBL091C 360 GTLPFCR|RY 0.087 . YBL091C 361 TLPFCRR|YL 0.164 . YBL091C 365 CRRYLDR|LG 0.089 . YBL091C 370 DRLGQEK|YL 0.073 . YBL091C 380 ALNNLVR|HG 0.076 . YBL091C 411 ILLHAHK|KE 0.057 . YBL091C 412 LLHAHKK|EV 0.183 . YBL091C 417 KKEVVSK|GD 0.080 . ____________________________^_________________

Fasta :-
>YBL091C ATGACAGACGCTGAAATAGAAAATTCCCCTGCTTCTGATTTAAAAGAATTGAATTTGGAG AATGAAGGCGTTGAACAGCAAGACCAGGCAAAAGCTGACGAGTCAGACCCAGTAGAAAGC AAAAAGAAGAAGAACAAGAAAAAGAAGAAGAAGAAAAGCAATGTGAAGAAGATTGAATTA CTGTTTCCAGATGGAAAGTACCCAGAAGGTGCGTGGATGGACTATCATCAAGATTTCAAT CTGCAAAGAACCACGGATGAAGAATCACGTTATTTGAAAAGGGATCTGGAAAGGGCCGAA CATTGGAATGATGTCAGAAAGGGTGCTGAGATACATCGTCGTGTGAGAAGGGCCATCAAG GACAGAATCGTTCCTGGGATGAAGTTAATGGATATCGCTGACATGATCGAAAATACTACA AGAAAGTATACAGGTGCCGAAAATTTATTAGCGATGGAGGATCCCAAATCTCAAGGTATT GGGTTTCCAACGGGTCTCTCTCTCAACCATTGTGCTGCACATTTCACACCCAATGCAGGC GACAAAACCGTTCTGAAATACGAAGACGTGATGAAGGTAGATTATGGTGTGCAGGTAAAC GGTAACATCATTGATTCTGCCTTTACTGTTTCCTTTGATCCACAATACGATAACCTGCTA GCCGCTGTAAAGGACGCTACTTACACGGGTATTAAAGAAGCGGGTATCGATGTGAGATTA ACCGACATCGGTGAAGCCATCCAAGAAGTTATGGAATCCTACGAAGTGGAAATCAATGGT GAGACTTACCAGGTTAAACCTTGTCGTAATCTATGTGGCCACAGTATCGCACCATATCGT ATCCACGGCGGTAAATCCGTTCCCATCGTCAAAAATGGGGACACTACAAAAATGGAGGAA GGTGAGCACTTTGCCATTGAAACTTTTGGTTCTACTGGTAGAGGTTATGTTACTGCCGGT GGGGAAGTTTCTCATTATGCCAGATCTGCTGAAGACCATCAGGTAATGCCCACGTTAGAC AGCGCCAAGAACTTGTTAAAAACGATAGACCGCAACTTTGGGACTTTACCGTTCTGTCGC CGATACCTAGACAGACTTGGCCAAGAGAAATACTTATTTGCGTTGAATAACTTGGTTAGA CACGGTTTAGTACAGGATTATCCACCATTGAACGATATCCCCGGATCCTACACTGCACAA TTCGAACACACCATCTTGTTGCATGCTCACAAAAAGGAAGTCGTTTCGAAAGGTGATGAC TACTGA
Download Fasta

Fasta :-

MTDAEIENSPASDLKELNLENEGVEQQDQAKADESDPVESKKKKNKKKKKKKSNVKKIEL LFPDGKYPEGAWMDYHQDFNLQRTTDEESRYLKRDLERAEHWNDVRKGAEIHRRVRRAIK DRIVPGMKLMDIADMIENTTRKYTGAENLLAMEDPKSQGIGFPTGLSLNHCAAHFTPNAG DKTVLKYEDVMKVDYGVQVNGNIIDSAFTVSFDPQYDNLLAAVKDATYTGIKEAGIDVRL TDIGEAIQEVMESYEVEINGETYQVKPCRNLCGHSIAPYRIHGGKSVPIVKNGDTTKMEE GEHFAIETFGSTGRGYVTAGGEVSHYARSAEDHQVMPTLDSAKNLLKTIDRNFGTLPFCR RYLDRLGQEKYLFALNNLVRHGLVQDYPPLNDIPGSYTAQFEHTILLHAHKKEVVSKGDD Y

Creatinase/aminopeptidase

title: active site
coordinates: H174,D194,D205,H274,E307,E402

	ID	Site	Position	Gscore	Iscore
	YBL091C	T	2	0.526	0.150

	ID	Site	Position	Gscore	Iscore
	YBL091C	T	2	0.526	0.150

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YBL091C	329 S	HYARSAEDH	0.992	unsp	YBL091C	416 S	KEVVSKGDD	0.996	unsp

YBL091C | methionine aminopeptidase

ID's

UniProt_ID: P38174

GEO Functions

Computed_GO_Component_IDs: GO:0005737

Computed_GO_Components: cytoplasm

Computed_GO_Function_IDs: GO:0004177 GO:0016787 GO:0046872 GO:0070006 GO:0008235 GO:0008233

Computed_GO_Functions: aminopeptidase activity hydrolase activity metal ion binding metalloaminopeptidase activity metalloexopeptidase activity peptidase activity

Computed_GO_Process_IDs: GO:0070084 GO:0006508

Computed_GO_Processes: protein initiator methionine removal proteolysis

Curated_GO_Component_IDs: GO:0005737 GO:0005634

Curated_GO_Components: cytoplasm nucleus

Curated_GO_Function_IDs: GO:0070006

Curated_GO_Functions: metalloaminopeptidase activity

Curated_GO_Processes: protein initiator methionine removal involved in protein maturation

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Creatinase/aminopeptidase

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YBL091C

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India