YDL007W | proteasome regulatory particle base subunit RPT2

UniProt_ID: P40327

Computed_GO_Component_IDs: GO:0005737 GO:0005634 GO:0000502
Computed_GO_Components: cytoplasm nucleus proteasome complex
Computed_GO_Function_IDs: GO:0005524 GO:0016787 GO:0000166 GO:0036402
Computed_GO_Functions: ATP binding hydrolase activity nucleotide binding proteasome-activating ATPase activity
Computed_GO_Process_IDs: GO:1901800 GO:0030163
Computed_GO_Processes: positive regulation of proteasomal protein catabolic process protein catabolic process
Curated_GO_Component_IDs: GO:0031597 GO:0031595 GO:0005634 GO:0008540
Curated_GO_Components: cytosolic proteasome complex nuclear proteasome complex nucleus proteasome regulatory particle, base subcomplex
Curated_GO_Function_IDs: GO:0016887 GO:0017025 GO:0036402
Curated_GO_Functions: ATPase activity TBP-class protein binding proteasome-activating ATPase activity
Curated_GO_Processes: cellular protein-containing complex localization nonfunctional rRNA decay peptide catabolic process positive regulation of RNA polymerase II transcriptional preinitiation complex assembly positive regulation of protein catabolic process proteasome regulatory particle assembly protein-containing comp

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YDL007W	OTHER	0.999984	0.000001	0.000014

No Results

Fasta :-
>YDL007W MGQGVSSGQDKKKKKGSNQKPKYEPPVQSKFGRKKRKGGPATAEKLPNIYPSTRCKLKLL RMERIKDHLLLEEEFVSNSEILKPFEKKQEEEKKQLEEIRGNPLSIGTLEEIIDDDHAIV TSPTMPDYYVSILSFVDKELLEPGCSVLLHHKTMSIVGVLQDDADPMVSVMKMDKSPTES YSDIGGLESQIQEIKESVELPLTHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQT SATFLRIVGSELIQKYLGDGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGER EIQRTMLELLNQLDGFDDRGDVKVIMATNKIETLDPALIRPGRIDRKILFENPDLSTKKK ILGIHTSKMNLSEDVNLETLVTTKDDLSGADIQAMCTEAGLLALRERRMQVTAEDFKQAK ERVMKNKVEENLEGLYL
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YDL007W.fa Sequence name : YDL007W Sequence length : 437 VALUES OF COMPUTED PARAMETERS Coef20 : 2.712 CoefTot : -4.886 ChDiff : -6 ZoneTo : 62 KR : 18 DE : 3 CleavSite : 38 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 0.853 1.147 0.004 0.422 MesoH : -0.651 0.321 -0.358 0.225 MuHd_075 : 33.139 17.877 9.357 6.773 MuHd_095 : 38.391 19.028 9.841 7.758 MuHd_100 : 37.152 19.026 10.313 7.207 MuHd_105 : 39.766 25.093 10.359 8.463 Hmax_075 : -2.683 -0.583 -2.709 1.003 Hmax_095 : 2.012 1.225 -1.442 2.144 Hmax_100 : 2.500 10.000 -1.442 2.330 Hmax_105 : 10.150 13.183 2.164 4.235 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.7821 0.2179 DFMC : 0.8017 0.1983

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 437 YDL007W MGQGVSSGQDKKKKKGSNQKPKYEPPVQSKFGRKKRKGGPATAEKLPNIYPSTRCKLKLLRMERIKDHLLLEEEFVSNSE 80 ILKPFEKKQEEEKKQLEEIRGNPLSIGTLEEIIDDDHAIVTSPTMPDYYVSILSFVDKELLEPGCSVLLHHKTMSIVGVL 160 QDDADPMVSVMKMDKSPTESYSDIGGLESQIQEIKESVELPLTHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQT 240 SATFLRIVGSELIQKYLGDGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRG 320 DVKVIMATNKIETLDPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVNLETLVTTKDDLSGADIQAMCTEAG 400 LLALRERRMQVTAEDFKQAKERVMKNKVEENLEGLYL 480 ...................................P............................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ..................................... 480 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 1 Name Pos Context Score Pred ____________________________v_________________ YDL007W 11 VSSGQDK|KK 0.077 . YDL007W 12 SSGQDKK|KK 0.092 . YDL007W 13 SGQDKKK|KK 0.145 . YDL007W 14 GQDKKKK|KG 0.114 . YDL007W 15 QDKKKKK|GS 0.179 . YDL007W 20 KKGSNQK|PK 0.064 . YDL007W 22 GSNQKPK|YE 0.100 . YDL007W 30 EPPVQSK|FG 0.076 . YDL007W 33 VQSKFGR|KK 0.197 . YDL007W 34 QSKFGRK|KR 0.088 . YDL007W 35 SKFGRKK|RK 0.114 . YDL007W 36 KFGRKKR|KG 0.735 *ProP* YDL007W 37 FGRKKRK|GG 0.098 . YDL007W 45 GPATAEK|LP 0.061 . YDL007W 54 NIYPSTR|CK 0.093 . YDL007W 56 YPSTRCK|LK 0.061 . YDL007W 58 STRCKLK|LL 0.067 . YDL007W 61 CKLKLLR|ME 0.076 . YDL007W 64 KLLRMER|IK 0.201 . YDL007W 66 LRMERIK|DH 0.069 . YDL007W 83 SNSEILK|PF 0.080 . YDL007W 87 ILKPFEK|KQ 0.065 . YDL007W 88 LKPFEKK|QE 0.106 . YDL007W 93 KKQEEEK|KQ 0.061 . YDL007W 94 KQEEEKK|QL 0.157 . YDL007W 100 KQLEEIR|GN 0.099 . YDL007W 138 ILSFVDK|EL 0.074 . YDL007W 152 SVLLHHK|TM 0.063 . YDL007W 172 PMVSVMK|MD 0.059 . YDL007W 175 SVMKMDK|SP 0.078 . YDL007W 195 SQIQEIK|ES 0.057 . YDL007W 214 YEEMGIK|PP 0.060 . YDL007W 217 MGIKPPK|GV 0.090 . YDL007W 229 GAPGTGK|TL 0.058 . YDL007W 234 GKTLLAK|AV 0.080 . YDL007W 246 TSATFLR|IV 0.236 . YDL007W 255 GSELIQK|YL 0.083 . YDL007W 262 YLGDGPR|LC 0.091 . YDL007W 265 DGPRLCR|QI 0.216 . YDL007W 269 LCRQIFK|VA 0.085 . YDL007W 290 IDAIGTK|RY 0.058 . YDL007W 291 DAIGTKR|YD 0.205 . YDL007W 300 SNSGGER|EI 0.095 . YDL007W 304 GEREIQR|TM 0.087 . YDL007W 319 LDGFDDR|GD 0.099 . YDL007W 323 DDRGDVK|VI 0.063 . YDL007W 330 VIMATNK|IE 0.056 . YDL007W 340 LDPALIR|PG 0.078 . YDL007W 343 ALIRPGR|ID 0.273 . YDL007W 346 RPGRIDR|KI 0.235 . YDL007W 347 PGRIDRK|IL 0.084 . YDL007W 358 NPDLSTK|KK 0.063 . YDL007W 359 PDLSTKK|KI 0.095 . YDL007W 360 DLSTKKK|IL 0.193 . YDL007W 368 LGIHTSK|MN 0.060 . YDL007W 384 ETLVTTK|DD 0.061 . YDL007W 405 AGLLALR|ER 0.065 . YDL007W 407 LLALRER|RM 0.076 . YDL007W 408 LALRERR|MQ 0.388 . YDL007W 417 VTAEDFK|QA 0.060 . YDL007W 420 EDFKQAK|ER 0.062 . YDL007W 422 FKQAKER|VM 0.099 . YDL007W 425 AKERVMK|NK 0.117 . YDL007W 427 ERVMKNK|VE 0.083 . ____________________________^_________________

Fasta :-
>YDL007W ATGGGACAAGGTGTATCATCTGGACAAGACAAAAAGAAGAAGAAGGGATCTAATCAGAAA CCCAAATATGAACCTCCCGTTCAATCTAAATTTGGTCGTAAGAAAAGAAAGGGAGGTCCA GCTACTGCTGAAAAATTACCCAACATATATCCAAGTACTCGTTGTAAGTTAAAGCTTCTA AGGATGGAACGAATTAAAGACCATTTGTTATTAGAAGAAGAATTTGTCTCTAACTCTGAA ATTTTAAAACCCTTTGAAAAGAAGCAGGAGGAGGAAAAGAAACAATTGGAAGAAATACGT GGAAATCCATTGAGCATTGGGACCCTTGAAGAAATTATAGACGATGATCATGCGATAGTG ACAAGTCCAACTATGCCTGATTATTATGTATCTATCTTATCCTTTGTCGATAAAGAGTTA CTAGAGCCTGGATGTTCTGTGTTATTGCATCATAAAACCATGTCCATCGTAGGTGTTTTA CAGGATGACGCCGATCCAATGGTTTCGGTCATGAAAATGGATAAGTCGCCAACAGAATCA TACAGTGATATTGGTGGCTTAGAATCTCAAATTCAAGAAATAAAAGAGTCTGTAGAGTTA CCGTTAACACACCCCGAACTGTATGAAGAGATGGGTATCAAACCTCCCAAGGGTGTGATT CTTTATGGTGCACCCGGTACAGGTAAGACATTGCTAGCAAAGGCTGTTGCAAATCAAACA TCTGCCACATTCTTAAGGATTGTTGGCTCAGAGTTAATTCAAAAATATTTGGGGGATGGT CCTAGGTTGTGTAGGCAAATTTTCAAAGTAGCGGGTGAGAATGCACCAAGTATTGTATTT ATTGATGAAATAGACGCCATTGGTACTAAAAGATATGACTCCAATAGTGGTGGTGAGAGA GAAATTCAGAGAACCATGCTGGAATTGCTGAACCAGCTGGACGGGTTCGACGACAGAGGG GATGTGAAGGTGATTATGGCCACTAACAAAATCGAGACTCTTGACCCAGCATTAATCAGG CCTGGGAGAATTGATCGTAAAATCTTATTTGAAAACCCTGATCTAAGTACTAAGAAAAAA ATTTTAGGGATTCACACTTCCAAGATGAATTTAAGTGAGGACGTTAATCTTGAAACTTTA GTAACAACAAAGGATGATTTGTCAGGCGCCGATATCCAGGCAATGTGTACAGAAGCAGGT TTGTTAGCCCTTAGAGAGAGAAGAATGCAAGTTACAGCGGAGGATTTTAAACAAGCCAAG GAGAGAGTCATGAAAAATAAAGTTGAGGAAAATTTAGAAGGTTTATACTTGTGA
Download Fasta

Fasta :-

MGQGVSSGQDKKKKKGSNQKPKYEPPVQSKFGRKKRKGGPATAEKLPNIYPSTRCKLKLL RMERIKDHLLLEEEFVSNSEILKPFEKKQEEEKKQLEEIRGNPLSIGTLEEIIDDDHAIV TSPTMPDYYVSILSFVDKELLEPGCSVLLHHKTMSIVGVLQDDADPMVSVMKMDKSPTES YSDIGGLESQIQEIKESVELPLTHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQT SATFLRIVGSELIQKYLGDGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGER EIQRTMLELLNQLDGFDDRGDVKVIMATNKIETLDPALIRPGRIDRKILFENPDLSTKKK ILGIHTSKMNLSEDVNLETLVTTKDDLSGADIQAMCTEAGLLALRERRMQVTAEDFKQAK ERVMKNKVEENLEGLYL

CATH

title: ATP binding site
coordinates: A224,P225,G226,T227,G228,K229,T230,L231,D282,N329

No Results

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YDL007W	294 S	KRYDSNSGG	0.997	unsp	YDL007W	294 S	KRYDSNSGG	0.997	unsp	YDL007W	294 S	KRYDSNSGG	0.997	unsp	YDL007W	296 S	YDSNSGGER	0.995	unsp	YDL007W	388 S	KDDLSGADI	0.993	unsp	YDL007W	176 S	KMDKSPTES	0.997	unsp	YDL007W	180 S	SPTESYSDI	0.995	unsp

YDL007W | proteasome regulatory particle base subunit RPT2

ID's

UniProt_ID: P40327

GEO Functions

Computed_GO_Component_IDs: GO:0005737 GO:0005634 GO:0000502

Computed_GO_Components: cytoplasm nucleus proteasome complex

Computed_GO_Function_IDs: GO:0005524 GO:0016787 GO:0000166 GO:0036402

Computed_GO_Functions: ATP binding hydrolase activity nucleotide binding proteasome-activating ATPase activity

Computed_GO_Process_IDs: GO:1901800 GO:0030163

Computed_GO_Processes: positive regulation of proteasomal protein catabolic process protein catabolic process

Curated_GO_Component_IDs: GO:0031597 GO:0031595 GO:0005634 GO:0008540

Curated_GO_Components: cytosolic proteasome complex nuclear proteasome complex nucleus proteasome regulatory particle, base subcomplex

Curated_GO_Function_IDs: GO:0016887 GO:0017025 GO:0036402

Curated_GO_Functions: ATPase activity TBP-class protein binding proteasome-activating ATPase activity

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

CATH

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YDL007W

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India