YER017C | AAA family ATPase AFG3

UniProt_ID: P39925

Computed_GO_Component_IDs: GO:0016021 GO:0016020 GO:0005743 GO:0031966 GO:0005739
Computed_GO_Components: integral component of membrane membrane mitochondrial inner membrane mitochondrial membrane mitochondrion
Computed_GO_Function_IDs: GO:0005524 GO:0016787 GO:0046872 GO:0004222 GO:0008237 GO:0000166 GO:0008233 GO:0008270
Computed_GO_Functions: ATP binding hydrolase activity metal ion binding metalloendopeptidase activity metallopeptidase activity nucleotide binding peptidase activity zinc ion binding
Computed_GO_Process_IDs: GO:0006508
Computed_GO_Processes: proteolysis
Curated_GO_Component_IDs: GO:0000329 GO:0005745 GO:0097002 GO:0005743 GO:0005739
Curated_GO_Components: fungal-type vacuole membrane m-AAA complex mitochondrial inner boundary membrane mitochondrial inner membrane mitochondrion
Curated_GO_Function_IDs: GO:0016887 GO:0008237
Curated_GO_Functions: ATPase activity metallopeptidase activity
Curated_GO_Processes: cellular protein-containing complex assembly cristae formation cytoplasmic translation mitochondrial fusion mitochondrial protein processing protein complex assembly protein import into mitochondrial matrix proteolysis replicative cell aging signal peptide processing

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YER017C	mTP	0.045037	0.000054	0.954909	CS pos: 71-72. TRL-NE. Pr: 0.2175

No Results

Fasta :-
>YER017C MMMWQRYARGAPRSLTSLSFGKASRISTVKPVLRSRMPVHQRLQTLSGLATRNTIHRSTQ IRSFHISWTRLNENRPNKEGEGKNNGNKDNNSNKEDGKDKRNEFGSLSEYFRSKEFANTM FLTIGFTIIFTLLTPSSNNSGDDSNRVLTFQDFKTKYLEKGLVSKIYVVNKFLVEAELVN TKQVVSFTIGSVDIFEEQMDQIQDLLNIPPRDRIPIKYIERSSPFTFLFPFLPTIILLGG LYFITRKINSSPPNANGGGGGGLGGMFNVGKSRAKLFNKETDIKISFKNVAGCDEAKQEI MEFVHFLKNPGKYTKLGAKIPRGAILSGPPGTGKTLLAKATAGEANVPFLSVSGSEFVEM FVGVGASRVRDLFTQARSMAPSIIFIDEIDAIGKERGKGGALGGANDEREATLNQLLVEM DGFTTSDQVVVLAGTNRPDVLDNALMRPGRFDRHIQIDSPDVNGRQQIYLVHLKRLNLDP LLTDDMNNLSGKLATLTPGFTGADIANACNEAALIAARHNDPYITIHHFEQAIERVIAGL EKKTRVLSKEEKRSVAYHEAGHAVCGWFLKYADPLLKVSIIPRGQGALGYAQYLPPDQYL ISEEQFRHRMIMALGGRVSEELHFPSVTSGAHDDFKKVTQMANAMVTSLGMSPKIGYLSF DQNDGNFKVNKPFSNKTARTIDLEVKSIVDDAHRACTELLTKNLDKVDLVAKELLRKEAI TREDMIRLLGPRPFKERNEAFEKYLDPKSNTEPPEAPAATN
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YER017C.fa Sequence name : YER017C Sequence length : 761 VALUES OF COMPUTED PARAMETERS Coef20 : 4.760 CoefTot : 0.526 ChDiff : 13 ZoneTo : 72 KR : 13 DE : 0 CleavSite : 72 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 2.294 2.053 0.368 0.865 MesoH : -0.248 0.474 -0.266 0.261 MuHd_075 : 44.554 21.433 9.603 9.836 MuHd_095 : 40.662 21.661 9.032 9.943 MuHd_100 : 40.223 24.846 8.551 10.473 MuHd_105 : 39.502 26.768 8.605 9.949 Hmax_075 : 14.200 10.700 2.003 4.040 Hmax_095 : 12.250 13.912 1.820 4.349 Hmax_100 : 13.900 14.900 0.655 5.150 Hmax_105 : 12.250 10.400 1.435 4.349 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.0007 0.9993 DFMC : 0.0005 0.9995 This protein is probably imported in mitochondria. f(Ser) = 0.1389 f(Arg) = 0.1528 CMi = 0.48924 CMi is the Chloroplast/Mitochondria Index It has been proposed by Von Heijne et al (Eur J Biochem,1989, 180: 535-545)

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 761 YER017C MMMWQRYARGAPRSLTSLSFGKASRISTVKPVLRSRMPVHQRLQTLSGLATRNTIHRSTQIRSFHISWTRLNENRPNKEG 80 EGKNNGNKDNNSNKEDGKDKRNEFGSLSEYFRSKEFANTMFLTIGFTIIFTLLTPSSNNSGDDSNRVLTFQDFKTKYLEK 160 GLVSKIYVVNKFLVEAELVNTKQVVSFTIGSVDIFEEQMDQIQDLLNIPPRDRIPIKYIERSSPFTFLFPFLPTIILLGG 240 LYFITRKINSSPPNANGGGGGGLGGMFNVGKSRAKLFNKETDIKISFKNVAGCDEAKQEIMEFVHFLKNPGKYTKLGAKI 320 PRGAILSGPPGTGKTLLAKATAGEANVPFLSVSGSEFVEMFVGVGASRVRDLFTQARSMAPSIIFIDEIDAIGKERGKGG 400 ALGGANDEREATLNQLLVEMDGFTTSDQVVVLAGTNRPDVLDNALMRPGRFDRHIQIDSPDVNGRQQIYLVHLKRLNLDP 480 LLTDDMNNLSGKLATLTPGFTGADIANACNEAALIAARHNDPYITIHHFEQAIERVIAGLEKKTRVLSKEEKRSVAYHEA 560 GHAVCGWFLKYADPLLKVSIIPRGQGALGYAQYLPPDQYLISEEQFRHRMIMALGGRVSEELHFPSVTSGAHDDFKKVTQ 640 MANAMVTSLGMSPKIGYLSFDQNDGNFKVNKPFSNKTARTIDLEVKSIVDDAHRACTELLTKNLDKVDLVAKELLRKEAI 720 TREDMIRLLGPRPFKERNEAFEKYLDPKSNTEPPEAPAATN 800 ........P....................................................................... 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ................................................................................ 480 ........................................................................P....... 560 ................................................................................ 640 ................................................................................ 720 ......................................... 800 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 2 Name Pos Context Score Pred ____________________________v_________________ YER017C 6 -MMMWQR|YA 0.143 . YER017C 9 MWQRYAR|GA 0.511 *ProP* YER017C 13 YARGAPR|SL 0.122 . YER017C 22 TSLSFGK|AS 0.066 . YER017C 25 SFGKASR|IS 0.083 . YER017C 30 SRISTVK|PV 0.082 . YER017C 34 TVKPVLR|SR 0.130 . YER017C 36 KPVLRSR|MP 0.089 . YER017C 42 RMPVHQR|LQ 0.081 . YER017C 52 LSGLATR|NT 0.085 . YER017C 57 TRNTIHR|ST 0.165 . YER017C 62 HRSTQIR|SF 0.290 . YER017C 70 FHISWTR|LN 0.074 . YER017C 75 TRLNENR|PN 0.121 . YER017C 78 NENRPNK|EG 0.153 . YER017C 83 NKEGEGK|NN 0.074 . YER017C 88 GKNNGNK|DN 0.072 . YER017C 94 KDNNSNK|ED 0.078 . YER017C 98 SNKEDGK|DK 0.078 . YER017C 100 KEDGKDK|RN 0.064 . YER017C 101 EDGKDKR|NE 0.196 . YER017C 112 SLSEYFR|SK 0.217 . YER017C 114 SEYFRSK|EF 0.062 . YER017C 146 SGDDSNR|VL 0.079 . YER017C 154 LTFQDFK|TK 0.056 . YER017C 156 FQDFKTK|YL 0.093 . YER017C 160 KTKYLEK|GL 0.064 . YER017C 165 EKGLVSK|IY 0.060 . YER017C 171 KIYVVNK|FL 0.079 . YER017C 182 AELVNTK|QV 0.062 . YER017C 211 LLNIPPR|DR 0.121 . YER017C 213 NIPPRDR|IP 0.072 . YER017C 217 RDRIPIK|YI 0.090 . YER017C 221 PIKYIER|SS 0.082 . YER017C 246 GLYFITR|KI 0.095 . YER017C 247 LYFITRK|IN 0.070 . YER017C 271 GMFNVGK|SR 0.079 . YER017C 273 FNVGKSR|AK 0.077 . YER017C 275 VGKSRAK|LF 0.066 . YER017C 279 RAKLFNK|ET 0.073 . YER017C 284 NKETDIK|IS 0.062 . YER017C 288 DIKISFK|NV 0.076 . YER017C 297 AGCDEAK|QE 0.068 . YER017C 308 EFVHFLK|NP 0.065 . YER017C 312 FLKNPGK|YT 0.071 . YER017C 315 NPGKYTK|LG 0.066 . YER017C 319 YTKLGAK|IP 0.060 . YER017C 322 LGAKIPR|GA 0.147 . YER017C 334 GPPGTGK|TL 0.062 . YER017C 339 GKTLLAK|AT 0.068 . YER017C 368 VGVGASR|VR 0.063 . YER017C 370 VGASRVR|DL 0.131 . YER017C 377 DLFTQAR|SM 0.129 . YER017C 394 EIDAIGK|ER 0.065 . YER017C 396 DAIGKER|GK 0.149 . YER017C 398 IGKERGK|GG 0.060 . YER017C 409 GGANDER|EA 0.098 . YER017C 437 VLAGTNR|PD 0.069 . YER017C 447 LDNALMR|PG 0.087 . YER017C 450 ALMRPGR|FD 0.359 . YER017C 453 RPGRFDR|HI 0.344 . YER017C 465 SPDVNGR|QQ 0.096 . YER017C 474 IYLVHLK|RL 0.054 . YER017C 475 YLVHLKR|LN 0.139 . YER017C 492 MNNLSGK|LA 0.071 . YER017C 518 AALIAAR|HN 0.109 . YER017C 535 FEQAIER|VI 0.086 . YER017C 542 VIAGLEK|KT 0.060 . YER017C 543 IAGLEKK|TR 0.070 . YER017C 545 GLEKKTR|VL 0.148 . YER017C 549 KTRVLSK|EE 0.066 . YER017C 552 VLSKEEK|RS 0.063 . YER017C 553 LSKEEKR|SV 0.514 *ProP* YER017C 570 VCGWFLK|YA 0.088 . YER017C 577 YADPLLK|VS 0.055 . YER017C 583 KVSIIPR|GQ 0.145 . YER017C 607 ISEEQFR|HR 0.087 . YER017C 609 EEQFRHR|MI 0.119 . YER017C 617 IMALGGR|VS 0.074 . YER017C 636 GAHDDFK|KV 0.095 . YER017C 637 AHDDFKK|VT 0.100 . YER017C 654 SLGMSPK|IG 0.072 . YER017C 668 QNDGNFK|VN 0.055 . YER017C 671 GNFKVNK|PF 0.075 . YER017C 676 NKPFSNK|TA 0.069 . YER017C 679 FSNKTAR|TI 0.147 . YER017C 686 TIDLEVK|SI 0.075 . YER017C 694 IVDDAHR|AC 0.073 . YER017C 702 CTELLTK|NL 0.060 . YER017C 706 LTKNLDK|VD 0.058 . YER017C 712 KVDLVAK|EL 0.063 . YER017C 716 VAKELLR|KE 0.068 . YER017C 717 AKELLRK|EA 0.096 . YER017C 722 RKEAITR|ED 0.086 . YER017C 727 TREDMIR|LL 0.117 . YER017C 732 IRLLGPR|PF 0.076 . YER017C 735 LGPRPFK|ER 0.097 . YER017C 737 PRPFKER|NE 0.077 . YER017C 743 RNEAFEK|YL 0.080 . YER017C 748 EKYLDPK|SN 0.080 . ____________________________^_________________

Fasta :-
>YER017C ATGATGATGTGGCAACGATATGCAAGGGGTGCGCCACGCTCATTGACATCACTCTCATTT GGTAAAGCTAGCCGCATATCAACAGTGAAGCCAGTGCTTCGCTCGCGCATGCCAGTTCAC CAGCGTTTGCAGACGTTATCTGGTCTGGCAACCAGAAACACAATACACCGTTCTACCCAA ATACGTTCCTTCCATATCTCATGGACAAGGTTAAATGAAAATAGGCCAAACAAAGAGGGT GAGGGCAAGAACAATGGTAATAAAGATAATAATAGCAATAAAGAAGATGGCAAAGACAAA AGAAATGAGTTTGGTTCATTATCAGAATACTTCAGATCTAAGGAATTTGCTAATACGATG TTTTTGACCATCGGATTCACAATTATATTTACTTTGCTCACACCTTCCAGTAACAACTCA GGAGACGACTCTAACCGCGTCTTGACTTTCCAGGATTTCAAAACAAAATACCTGGAGAAG GGTCTTGTGTCCAAGATTTACGTCGTTAATAAGTTTCTCGTAGAGGCCGAATTAGTCAAT ACAAAGCAAGTTGTATCGTTCACCATTGGTTCAGTAGATATTTTTGAGGAACAGATGGAC CAGATCCAGGACCTCTTGAACATTCCTCCTCGGGATCGTATCCCCATCAAATACATTGAG AGATCTTCTCCCTTCACATTTTTGTTCCCCTTCCTGCCCACCATCATTCTGCTTGGTGGC CTTTACTTCATAACCAGAAAAATAAATAGTTCACCACCAAATGCCAATGGTGGTGGTGGA GGAGGCCTCGGCGGCATGTTTAATGTTGGAAAATCCAGAGCAAAGCTCTTCAATAAGGAA ACAGACATTAAAATTTCATTTAAAAATGTTGCCGGTTGTGATGAAGCTAAACAGGAAATC ATGGAATTTGTTCACTTTTTGAAGAACCCAGGTAAGTACACTAAATTGGGTGCCAAGATT CCACGAGGCGCTATTCTTTCTGGACCCCCAGGTACCGGTAAGACTCTCTTGGCCAAGGCC ACCGCAGGTGAGGCGAACGTGCCCTTCTTGTCAGTATCAGGTTCTGAGTTCGTCGAAATG TTCGTTGGGGTGGGTGCTTCACGTGTAAGAGACTTGTTTACTCAAGCAAGGTCTATGGCC CCCTCGATTATCTTTATAGATGAAATTGACGCTATCGGTAAAGAAAGAGGCAAAGGCGGC GCTCTCGGTGGCGCTAACGATGAAAGAGAAGCTACGCTGAATCAATTATTGGTGGAAATG GACGGATTCACTACTTCCGACCAAGTCGTAGTCCTTGCGGGTACAAATAGGCCCGATGTG TTGGATAATGCTTTGATGAGACCGGGAAGGTTCGATAGACATATCCAAATTGATTCTCCT GATGTCAATGGTAGGCAGCAAATATACCTGGTTCACTTGAAAAGACTGAATCTGGATCCC CTTCTTACAGATGATATGAATAATCTTTCTGGGAAATTGGCTACGCTTACTCCAGGTTTT ACTGGTGCAGATATCGCTAATGCTTGTAATGAGGCTGCATTAATCGCTGCCAGACATAAT GACCCATATATCACTATCCATCACTTTGAGCAAGCCATTGAAAGAGTCATTGCGGGACTA GAGAAGAAAACAAGAGTCCTTTCTAAGGAAGAAAAAAGGTCAGTGGCCTATCATGAGGCA GGACATGCCGTTTGTGGTTGGTTTCTAAAATATGCGGATCCACTTCTGAAAGTAAGCATC ATCCCGCGTGGACAAGGTGCTTTAGGCTATGCCCAGTACCTACCACCGGATCAATATTTG ATATCTGAGGAGCAATTCAGACATAGAATGATCATGGCTCTTGGTGGCCGTGTTTCTGAG GAGCTACATTTTCCATCGGTGACTAGCGGTGCTCATGATGATTTCAAAAAGGTTACACAG ATGGCAAATGCCATGGTTACATCCCTAGGAATGTCACCCAAGATTGGCTACCTGTCGTTT GATCAGAATGATGGAAACTTCAAAGTTAACAAACCCTTCAGTAATAAAACGGCAAGAACC ATTGATTTAGAAGTTAAATCTATAGTAGATGATGCACACCGAGCTTGTACAGAATTGCTA ACCAAAAATTTGGACAAAGTCGATCTTGTCGCAAAAGAATTGCTACGTAAGGAAGCAATT ACTAGAGAAGACATGATTAGATTATTGGGTCCAAGGCCATTCAAGGAAAGGAACGAGGCT TTTGAAAAATATTTGGATCCAAAGAGCAATACCGAACCGCCTGAGGCACCTGCAGCAACA AATTAA
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Fasta :-

MMMWQRYARGAPRSLTSLSFGKASRISTVKPVLRSRMPVHQRLQTLSGLATRNTIHRSTQ IRSFHISWTRLNENRPNKEGEGKNNGNKDNNSNKEDGKDKRNEFGSLSEYFRSKEFANTM FLTIGFTIIFTLLTPSSNNSGDDSNRVLTFQDFKTKYLEKGLVSKIYVVNKFLVEAELVN TKQVVSFTIGSVDIFEEQMDQIQDLLNIPPRDRIPIKYIERSSPFTFLFPFLPTIILLGG LYFITRKINSSPPNANGGGGGGLGGMFNVGKSRAKLFNKETDIKISFKNVAGCDEAKQEI MEFVHFLKNPGKYTKLGAKIPRGAILSGPPGTGKTLLAKATAGEANVPFLSVSGSEFVEM FVGVGASRVRDLFTQARSMAPSIIFIDEIDAIGKERGKGGALGGANDEREATLNQLLVEM DGFTTSDQVVVLAGTNRPDVLDNALMRPGRFDRHIQIDSPDVNGRQQIYLVHLKRLNLDP LLTDDMNNLSGKLATLTPGFTGADIANACNEAALIAARHNDPYITIHHFEQAIERVIAGL EKKTRVLSKEEKRSVAYHEAGHAVCGWFLKYADPLLKVSIIPRGQGALGYAQYLPPDQYL ISEEQFRHRMIMALGGRVSEELHFPSVTSGAHDDFKKVTQMANAMVTSLGMSPKIGYLSF DQNDGNFKVNKPFSNKTARTIDLEVKSIVDDAHRACTELLTKNLDKVDLVAKELLRKEAI TREDMIRLLGPRPFKERNEAFEKYLDPKSNTEPPEAPAATN

Extended AAA-ATPase domain

title: ATP binding site
coordinates: P329,P330,G331,T332,G333,K334,T335,L336,D387,N436

	ID	Site	Position	Gscore	Iscore
	YER017C	T	760	0.671	0.102

	ID	Site	Position	Gscore	Iscore
	YER017C	T	760	0.671	0.102

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YER017C	548 S	TRVLSKEEK	0.998	unsp	YER017C	652 S	SLGMSPKIG	0.995	unsp

YER017C | AAA family ATPase AFG3

ID's

UniProt_ID: P39925

GEO Functions

Computed_GO_Component_IDs: GO:0016021 GO:0016020 GO:0005743 GO:0031966 GO:0005739

Computed_GO_Components: integral component of membrane membrane mitochondrial inner membrane mitochondrial membrane mitochondrion

Computed_GO_Function_IDs: GO:0005524 GO:0016787 GO:0046872 GO:0004222 GO:0008237 GO:0000166 GO:0008233 GO:0008270

Computed_GO_Functions: ATP binding hydrolase activity metal ion binding metalloendopeptidase activity metallopeptidase activity nucleotide binding peptidase activity zinc ion binding

Computed_GO_Process_IDs: GO:0006508

Computed_GO_Processes: proteolysis

Curated_GO_Component_IDs: GO:0000329 GO:0005745 GO:0097002 GO:0005743 GO:0005739

Curated_GO_Components: fungal-type vacuole membrane m-AAA complex mitochondrial inner boundary membrane mitochondrial inner membrane mitochondrion

Curated_GO_Function_IDs: GO:0016887 GO:0008237

Curated_GO_Functions: ATPase activity metallopeptidase activity

Curated_GO_Processes: cellular protein-containing complex assembly cristae formation cytoplasmic translation mitochondrial fusion mitochondrial protein processing protein complex assembly protein import into mitochondrial matrix proteolysis replicative cell aging signal peptide processing

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Extended AAA-ATPase domain

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YER017C

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India