YGL048C | proteasome regulatory particle base subunit RPT6

UniProt_ID: Q01939

Computed_GO_Component_IDs: GO:0005737 GO:0005634 GO:0000502
Computed_GO_Components: cytoplasm nucleus proteasome complex
Computed_GO_Function_IDs: GO:0005524 GO:0016787 GO:0000166 GO:0036402
Computed_GO_Functions: ATP binding hydrolase activity nucleotide binding proteasome-activating ATPase activity
Computed_GO_Process_IDs: GO:1901800 GO:0030163
Computed_GO_Processes: positive regulation of proteasomal protein catabolic process protein catabolic process
Curated_GO_Component_IDs: GO:0031597 GO:0031595 GO:0005634 GO:0008540 GO:0034515
Curated_GO_Components: cytosolic proteasome complex nuclear proteasome complex nucleus proteasome regulatory particle, base subcomplex proteasome storage granule
Curated_GO_Function_IDs: GO:0016887 GO:0017025 GO:0036402 GO:0019904 GO:0031625
Curated_GO_Functions: ATPase activity TBP-class protein binding proteasome-activating ATPase activity protein domain specific binding ubiquitin protein ligase binding
Curated_GO_Processes: chromatin remodeling negative regulation of DNA-binding transcription factor activity nonfunctional rRNA decay nucleotide-excision repair positive regulation of DNA-binding transcription factor activity positive regulation of RNA polymerase II transcriptional preinitiation complex assembly positive

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YGL048C	OTHER	0.999919	0.000029	0.000052

No Results

Fasta :-
>YGL048C MTAAVTSSNIVLETHESGIKPYFEQKIQETELKIRSKTENVRRLEAQRNALNDKVRFIKD ELRLLQEPGSYVGEVIKIVSDKKVLVKVQPEGKYIVDVAKDINVKDLKASQRVCLRSDSY MLHKVLENKADPLVSLMMVEKVPDSTYDMVGGLTKQIKEIKEVIELPVKHPELFESLGIA QPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREH APSIIFMDEIDSIGSTRVEGSGGGDSEVQRTMLELLNQLDGFETSKNIKIIMATNRLDIL DPALLRPGRIDRKIEFPPPSVAARAEILRIHSRKMNLTRGINLRKVAEKMNGCSGADVKG VCTEAGMYALRERRIHVTQEDFELAVGKVMNKNQETAISVAKLFK
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YGL048C.fa Sequence name : YGL048C Sequence length : 405 VALUES OF COMPUTED PARAMETERS Coef20 : 4.025 CoefTot : 0.494 ChDiff : 8 ZoneTo : 12 KR : 0 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 0.412 0.835 -0.107 0.445 MesoH : -0.855 0.199 -0.439 0.189 MuHd_075 : 7.431 7.960 1.047 1.986 MuHd_095 : 15.144 6.577 4.543 2.057 MuHd_100 : 19.214 9.756 5.493 2.987 MuHd_105 : 23.026 11.705 6.064 3.429 Hmax_075 : 11.550 12.717 0.323 4.422 Hmax_095 : 10.938 6.800 1.532 2.970 Hmax_100 : 11.700 11.900 2.184 3.990 Hmax_105 : 11.300 10.000 1.905 3.330 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.8303 0.1697 DFMC : 0.7735 0.2265

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 405 YGL048C MTAAVTSSNIVLETHESGIKPYFEQKIQETELKIRSKTENVRRLEAQRNALNDKVRFIKDELRLLQEPGSYVGEVIKIVS 80 DKKVLVKVQPEGKYIVDVAKDINVKDLKASQRVCLRSDSYMLHKVLENKADPLVSLMMVEKVPDSTYDMVGGLTKQIKEI 160 KEVIELPVKHPELFESLGIAQPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREH 240 APSIIFMDEIDSIGSTRVEGSGGGDSEVQRTMLELLNQLDGFETSKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPS 320 VAARAEILRIHSRKMNLTRGINLRKVAEKMNGCSGADVKGVCTEAGMYALRERRIHVTQEDFELAVGKVMNKNQETAISV 400 AKLFK 480 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ..... 480 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ YGL048C 20 THESGIK|PY 0.063 . YGL048C 26 KPYFEQK|IQ 0.073 . YGL048C 33 IQETELK|IR 0.068 . YGL048C 35 ETELKIR|SK 0.113 . YGL048C 37 ELKIRSK|TE 0.059 . YGL048C 42 SKTENVR|RL 0.102 . YGL048C 43 KTENVRR|LE 0.097 . YGL048C 48 RRLEAQR|NA 0.078 . YGL048C 54 RNALNDK|VR 0.059 . YGL048C 56 ALNDKVR|FI 0.193 . YGL048C 59 DKVRFIK|DE 0.120 . YGL048C 63 FIKDELR|LL 0.071 . YGL048C 77 YVGEVIK|IV 0.081 . YGL048C 82 IKIVSDK|KV 0.082 . YGL048C 83 KIVSDKK|VL 0.094 . YGL048C 87 DKKVLVK|VQ 0.058 . YGL048C 93 KVQPEGK|YI 0.072 . YGL048C 100 YIVDVAK|DI 0.079 . YGL048C 105 AKDINVK|DL 0.071 . YGL048C 108 INVKDLK|AS 0.059 . YGL048C 112 DLKASQR|VC 0.078 . YGL048C 116 SQRVCLR|SD 0.148 . YGL048C 124 DSYMLHK|VL 0.064 . YGL048C 129 HKVLENK|AD 0.059 . YGL048C 141 SLMMVEK|VP 0.064 . YGL048C 155 MVGGLTK|QI 0.067 . YGL048C 158 GLTKQIK|EI 0.073 . YGL048C 161 KQIKEIK|EV 0.074 . YGL048C 169 VIELPVK|HP 0.058 . YGL048C 183 LGIAQPK|GV 0.092 . YGL048C 195 GPPGTGK|TL 0.059 . YGL048C 200 GKTLLAR|AV 0.133 . YGL048C 209 AHHTDCK|FI 0.079 . YGL048C 212 TDCKFIR|VS 0.168 . YGL048C 221 GAELVQK|YI 0.099 . YGL048C 228 YIGEGSR|MV 0.115 . YGL048C 231 EGSRMVR|EL 0.260 . YGL048C 238 ELFVMAR|EH 0.090 . YGL048C 257 DSIGSTR|VE 0.105 . YGL048C 270 GDSEVQR|TM 0.103 . YGL048C 286 DGFETSK|NI 0.064 . YGL048C 289 ETSKNIK|II 0.069 . YGL048C 296 IIMATNR|LD 0.073 . YGL048C 306 LDPALLR|PG 0.069 . YGL048C 309 ALLRPGR|ID 0.238 . YGL048C 312 RPGRIDR|KI 0.302 . YGL048C 313 PGRIDRK|IE 0.069 . YGL048C 324 PPSVAAR|AE 0.118 . YGL048C 329 ARAEILR|IH 0.096 . YGL048C 333 ILRIHSR|KM 0.084 . YGL048C 334 LRIHSRK|MN 0.108 . YGL048C 339 RKMNLTR|GI 0.107 . YGL048C 344 TRGINLR|KV 0.163 . YGL048C 345 RGINLRK|VA 0.096 . YGL048C 349 LRKVAEK|MN 0.093 . YGL048C 359 CSGADVK|GV 0.095 . YGL048C 371 AGMYALR|ER 0.081 . YGL048C 373 MYALRER|RI 0.099 . YGL048C 374 YALRERR|IH 0.393 . YGL048C 388 FELAVGK|VM 0.064 . YGL048C 392 VGKVMNK|NQ 0.065 . YGL048C 402 TAISVAK|LF 0.066 . YGL048C 405 SVAKLFK|-- 0.071 . ____________________________^_________________

Fasta :-
>YGL048C ATGACAGCTGCTGTAACATCCTCCAATATAGTATTAGAAACCCACGAAAGTGGTATCAAA CCATATTTTGAACAGAAGATCCAAGAAACAGAATTAAAGATCCGCTCCAAAACAGAAAAT GTTCGCAGACTGGAAGCTCAAAGGAATGCATTGAATGACAAAGTACGTTTTATCAAGGAC GAACTGCGTCTATTACAGGAACCTGGATCTTATGTGGGTGAAGTTATAAAGATCGTGTCT GACAAAAAAGTTCTCGTTAAAGTGCAACCTGAGGGAAAATACATCGTGGATGTTGCAAAA GATATAAACGTGAAGGACTTAAAGGCATCTCAAAGAGTTTGTCTAAGGAGTGACTCTTAT ATGTTGCATAAAGTTCTTGAGAATAAGGCTGACCCACTAGTTTCGTTGATGATGGTGGAA AAAGTTCCTGATTCCACATACGATATGGTTGGTGGTTTGACAAAGCAAATAAAGGAGATT AAAGAAGTTATTGAATTGCCCGTAAAACATCCTGAACTTTTTGAAAGTTTGGGTATTGCG CAACCAAAGGGTGTCATCTTATATGGCCCCCCTGGTACAGGGAAAACCTTATTGGCAAGA GCTGTCGCACATCACACTGATTGTAAATTCATCAGGGTCAGTGGTGCGGAACTGGTACAA AAGTATATCGGCGAAGGTTCCCGTATGGTCCGTGAGCTGTTTGTGATGGCTAGAGAACAT GCTCCCTCAATTATCTTTATGGATGAAATCGATTCCATTGGCTCTACTCGTGTAGAAGGT TCTGGTGGTGGTGATTCAGAAGTTCAAAGAACAATGTTAGAACTACTAAACCAATTGGAC GGGTTTGAAACTTCTAAAAATATCAAGATCATAATGGCCACGAATAGACTAGATATTCTA GATCCAGCACTTTTGAGACCCGGTAGAATAGATAGGAAGATTGAATTTCCACCTCCAAGT GTCGCAGCTAGAGCTGAAATTTTAAGAATCCATTCCAGAAAAATGAATCTAACTCGTGGT ATCAACTTGAGAAAGGTTGCTGAAAAGATGAACGGTTGTTCTGGTGCCGATGTCAAAGGT GTCTGTACAGAAGCTGGTATGTATGCTTTAAGAGAAAGAAGAATACACGTTACTCAAGAA GACTTCGAACTCGCTGTGGGTAAGGTTATGAACAAGAACCAAGAAACGGCCATTTCTGTC GCCAAGCTGTTCAAGTGA
Download Fasta

Fasta :-

MTAAVTSSNIVLETHESGIKPYFEQKIQETELKIRSKTENVRRLEAQRNALNDKVRFIKD ELRLLQEPGSYVGEVIKIVSDKKVLVKVQPEGKYIVDVAKDINVKDLKASQRVCLRSDSY MLHKVLENKADPLVSLMMVEKVPDSTYDMVGGLTKQIKEIKEVIELPVKHPELFESLGIA QPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREH APSIIFMDEIDSIGSTRVEGSGGGDSEVQRTMLELLNQLDGFETSKNIKIIMATNRLDIL DPALLRPGRIDRKIEFPPPSVAARAEILRIHSRKMNLTRGINLRKVAEKMNGCSGADVKG VCTEAGMYALRERRIHVTQEDFELAVGKVMNKNQETAISVAKLFK

CATH

title: ATP binding site
coordinates: P190,P191,G192,T193,G194,K195,T196,L197,D248,N295

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	YGL048C	T	2	0.553	0.172	YGL048C	T	6	0.514	0.234

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	YGL048C	T	2	0.553	0.172	YGL048C	T	6	0.514	0.234

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YGL048C	145 S	KVPDSTYDM	0.997	unsp	YGL048C	332 S	LRIHSRKMN	0.995	unsp

YGL048C | proteasome regulatory particle base subunit RPT6

ID's

UniProt_ID: Q01939

GEO Functions

Computed_GO_Component_IDs: GO:0005737 GO:0005634 GO:0000502

Computed_GO_Components: cytoplasm nucleus proteasome complex

Computed_GO_Function_IDs: GO:0005524 GO:0016787 GO:0000166 GO:0036402

Computed_GO_Functions: ATP binding hydrolase activity nucleotide binding proteasome-activating ATPase activity

Computed_GO_Process_IDs: GO:1901800 GO:0030163

Computed_GO_Processes: positive regulation of proteasomal protein catabolic process protein catabolic process

Curated_GO_Component_IDs: GO:0031597 GO:0031595 GO:0005634 GO:0008540 GO:0034515

Curated_GO_Components: cytosolic proteasome complex nuclear proteasome complex nucleus proteasome regulatory particle, base subcomplex proteasome storage granule

Curated_GO_Function_IDs: GO:0016887 GO:0017025 GO:0036402 GO:0019904 GO:0031625

Curated_GO_Functions: ATPase activity TBP-class protein binding proteasome-activating ATPase activity protein domain specific binding ubiquitin protein ligase binding

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

CATH

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YGL048C

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India