YGR253C | proteasome core particle subunit alpha 5

UniProt_ID: P32379

Computed_GO_Component_IDs: GO:0005737 GO:0005634 GO:0000502 GO:0005839 GO:0019773
Computed_GO_Components: cytoplasm nucleus proteasome complex proteasome core complex proteasome core complex, alpha-subunit complex
Computed_GO_Function_IDs: GO:0004175 GO:0016787 GO:0008233 GO:0004298
Computed_GO_Functions: endopeptidase activity hydrolase activity peptidase activity threonine-type endopeptidase activity
Computed_GO_Process_IDs: GO:0043161 GO:0006508 GO:0051603 GO:0006511
Computed_GO_Processes: proteasome-mediated ubiquitin-dependent protein catabolic process proteolysis proteolysis involved in cellular protein catabolic process ubiquitin-dependent protein catabolic process
Curated_GO_Component_IDs: GO:0005737 GO:0042175 GO:0005634 GO:0005839 GO:0019773 GO:0034515
Curated_GO_Components: cytoplasm nuclear outer membrane-endoplasmic reticulum membrane network nucleus proteasome core complex proteasome core complex, alpha-subunit complex proteasome storage granule
Curated_GO_Function_IDs: GO:0004175 GO:0003674
Curated_GO_Functions: endopeptidase activity molecular_function
Curated_GO_Processes: proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YGR253C	OTHER	0.999409	0.000217	0.000374

No Results

Fasta :-
>YGR253C MFLTRSEYDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLE SDSIEKIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLA LRFGEGASGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQ AELLNEWHSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELI KELKEKEAAESPEEADVEMS
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YGR253C.fa Sequence name : YGR253C Sequence length : 260 VALUES OF COMPUTED PARAMETERS Coef20 : 3.961 CoefTot : 0.369 ChDiff : -21 ZoneTo : 6 KR : 1 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 0.600 1.047 0.011 0.461 MesoH : -0.939 0.250 -0.426 0.167 MuHd_075 : 25.770 13.438 5.392 6.742 MuHd_095 : 18.131 9.688 4.532 4.365 MuHd_100 : 11.276 7.779 2.592 3.083 MuHd_105 : 5.813 8.676 1.923 2.594 Hmax_075 : 3.063 4.500 -1.081 3.080 Hmax_095 : 11.800 5.700 0.856 3.450 Hmax_100 : 3.000 3.000 -1.467 2.890 Hmax_105 : -1.050 2.400 -1.764 1.003 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.6618 0.3382 DFMC : 0.7261 0.2739

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 260 YGR253C MFLTRSEYDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKIVEIDRHIGCAMSG 80 LTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGASGEERLMSRPFGVALLIAGHDADDGYQLFHAEP 160 SGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELI 240 KELKEKEAAESPEEADVEMS 320 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 .................... 320 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ YGR253C 5 --MFLTR|SE 0.126 . YGR253C 10 TRSEYDR|GV 0.241 . YGR253C 20 TFSPEGR|LF 0.103 . YGR253C 32 YSLEAIK|LG 0.065 . YGR253C 43 AIGIATK|EG 0.057 . YGR253C 52 VVLGVEK|RA 0.059 . YGR253C 53 VLGVEKR|AT 0.258 . YGR253C 66 ESDSIEK|IV 0.073 . YGR253C 72 KIVEIDR|HI 0.104 . YGR253C 86 GLTADAR|SM 0.123 . YGR253C 93 SMIEHAR|TA 0.104 . YGR253C 122 VCDLALR|FG 0.076 . YGR253C 132 GASGEER|LM 0.089 . YGR253C 136 EERLMSR|PF 0.107 . YGR253C 166 PSGTFYR|YN 0.132 . YGR253C 170 FYRYNAK|AI 0.081 . YGR253C 194 HSSLTLK|EA 0.075 . YGR253C 202 AELLVLK|IL 0.059 . YGR253C 205 LVLKILK|QV 0.070 . YGR253C 211 KQVMEEK|LD 0.060 . YGR253C 224 QLSCITK|QD 0.075 . YGR253C 229 TKQDGFK|IY 0.070 . YGR253C 235 KIYDNEK|TA 0.064 . YGR253C 241 KTAELIK|EL 0.067 . YGR253C 244 ELIKELK|EK 0.067 . YGR253C 246 IKELKEK|EA 0.077 . ____________________________^_________________

Fasta :-
>YGR253C ATGTTCTTAACTAGAAGTGAATATGATCGTGGTGTAAGCACATTTTCCCCAGAAGGGAGG TTATTCCAAGTTGAGTATTCTTTGGAGGCCATCAAATTAGGATCTACAGCAATTGGTATT GCCACGAAAGAAGGTGTTGTACTAGGTGTGGAGAAACGTGCCACCTCACCACTATTAGAA TCTGATTCTATTGAGAAAATCGTGGAGATTGATCGTCATATTGGTTGTGCAATGAGTGGG CTTACAGCAGATGCTCGTTCCATGATTGAACATGCGCGTACTGCTGCAGTAACGCATAAT CTATACTACGATGAAGACATCAATGTTGAGTCCTTAACGCAATCGGTGTGTGATCTTGCT CTAAGGTTCGGTGAAGGTGCCTCTGGTGAAGAAAGACTAATGTCTCGACCATTCGGGGTT GCCTTGTTAATTGCTGGCCATGATGCGGATGATGGTTATCAACTTTTCCATGCAGAACCA TCTGGGACATTTTACCGTTATAATGCCAAAGCCATTGGTTCAGGCTCTGAAGGAGCACAA GCAGAATTATTGAATGAATGGCATTCTTCTTTAACTTTGAAAGAAGCTGAGCTTCTTGTT CTAAAAATCCTAAAGCAAGTGATGGAAGAGAAACTTGATGAAAATAACGCGCAATTGAGT TGTATAACAAAGCAAGACGGATTCAAAATATATGATAACGAAAAAACTGCTGAATTGATA AAAGAGTTGAAAGAGAAAGAAGCTGCAGAAAGTCCAGAAGAAGCGGATGTTGAAATGTCA TAA
Download Fasta

Fasta :-

MFLTRSEYDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLE SDSIEKIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLA LRFGEGASGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQ AELLNEWHSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELI KELKEKEAAESPEEADVEMS

Proteasome subunits

title: active site
coordinates: S35,E51,R53,K66,S174

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	YGR253C	S	260	0.573	0.269	YGR253C	T	4	0.520	0.058

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	YGR253C	S	260	0.573	0.269	YGR253C	T	4	0.520	0.058

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YGR253C	87 S	ADARSMIEH	0.996	unsp	YGR253C	251 S	EAAESPEEA	0.998	unsp

YGR253C | proteasome core particle subunit alpha 5

ID's

UniProt_ID: P32379

GEO Functions

Computed_GO_Component_IDs: GO:0005737 GO:0005634 GO:0000502 GO:0005839 GO:0019773

Computed_GO_Components: cytoplasm nucleus proteasome complex proteasome core complex proteasome core complex, alpha-subunit complex

Computed_GO_Function_IDs: GO:0004175 GO:0016787 GO:0008233 GO:0004298

Computed_GO_Functions: endopeptidase activity hydrolase activity peptidase activity threonine-type endopeptidase activity

Computed_GO_Process_IDs: GO:0043161 GO:0006508 GO:0051603 GO:0006511

Computed_GO_Processes: proteasome-mediated ubiquitin-dependent protein catabolic process proteolysis proteolysis involved in cellular protein catabolic process ubiquitin-dependent protein catabolic process

Curated_GO_Component_IDs: GO:0005737 GO:0042175 GO:0005634 GO:0005839 GO:0019773 GO:0034515

Curated_GO_Components: cytoplasm nuclear outer membrane-endoplasmic reticulum membrane network nucleus proteasome core complex proteasome core complex, alpha-subunit complex proteasome storage granule

Curated_GO_Function_IDs: GO:0004175 GO:0003674

Curated_GO_Functions: endopeptidase activity molecular_function

Curated_GO_Processes: proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Proteasome subunits

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YGR253C

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India