YIR039C | aspartyl protease

UniProt_ID: P40583

Computed_GO_Component_IDs: GO:0031225 GO:0016020 GO:0005886
Computed_GO_Components: anchored component of membrane membrane plasma membrane
Computed_GO_Function_IDs: GO:0004190 GO:0016787 GO:0008233
Computed_GO_Functions: aspartic-type endopeptidase activity hydrolase activity peptidase activity
Computed_GO_Process_IDs: GO:0006508
Computed_GO_Processes: proteolysis
Curated_GO_Component_IDs: GO:0031362 GO:0005576 GO:0009277
Curated_GO_Components: anchored component of external side of plasma membrane extracellular region fungal-type cell wall
Curated_GO_Function_IDs: GO:0004190
Curated_GO_Functions: aspartic-type endopeptidase activity
Curated_GO_Processes: fungal-type cell wall organization protein catabolic process proteolysis

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YIR039C	SP	0.000246	0.999741	0.000013	CS pos: 21-22. VLG-SS. Pr: 0.4445

No Results

Fasta :-
>YIR039C MQLISILSLLSSLMCSLTVLGSSASSYVKFPVQKLADIINICTQDVSTVFKRNEVLNTTV INGIGVYVVKMEIGTPPQTLYLQLDTGSSDMIVNNADIAYCKSMSDGSDYASTDNYELTA TFNGLPSTTISSEAYNTLCSYWGTFDASNSSTFENNATFFNNTYGDGTYYAGTYGTDVVS FENITLNDFTFGVSNDTIGNPSGILGISLPIAEFTDGIEYALALNRTPFIYDNFPMELKN QGKINKIAYSLFLNGPDAHFGSILFGAVDKSKYTGQLYTLPMLQAFNTLGSNPGMIITAQ SVAILDSESGNKTVSDIQFPVMLDSGTTFSYLPTEIAEAIGKSFDGEYSSDDQGYIFDCS KVNDTLLSVDFGGFNISANISNFVTSAKDRCVLNVKQSESTYMLGDAFLVDAYVVYDLEN YEISIAQASFNNQEEDIEVISDTVPGATPAPGYFSTWVYKPGSPIGTGDFINVSWTSYSE FSQYKSLLATAAQSDDASSFSSSGGSSESTTKKQNAGYKYRSSFSFSLLSFISYFLL
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YIR039C.fa Sequence name : YIR039C Sequence length : 537 VALUES OF COMPUTED PARAMETERS Coef20 : 5.072 CoefTot : 1.070 ChDiff : -32 ZoneTo : 36 KR : 2 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 2.071 2.100 0.451 0.616 MesoH : 0.077 0.762 -0.165 0.297 MuHd_075 : 17.340 15.547 5.506 3.698 MuHd_095 : 19.115 19.888 6.594 6.310 MuHd_100 : 14.871 15.988 5.217 5.384 MuHd_105 : 14.777 20.267 4.453 6.169 Hmax_075 : 9.917 18.375 0.608 5.049 Hmax_095 : 13.650 16.600 2.855 5.460 Hmax_100 : 13.200 23.100 2.664 7.380 Hmax_105 : 14.700 23.188 1.557 6.842 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.6770 0.3230 DFMC : 0.5113 0.4887

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 537 YIR039C MQLISILSLLSSLMCSLTVLGSSASSYVKFPVQKLADIINICTQDVSTVFKRNEVLNTTVINGIGVYVVKMEIGTPPQTL 80 YLQLDTGSSDMIVNNADIAYCKSMSDGSDYASTDNYELTATFNGLPSTTISSEAYNTLCSYWGTFDASNSSTFENNATFF 160 NNTYGDGTYYAGTYGTDVVSFENITLNDFTFGVSNDTIGNPSGILGISLPIAEFTDGIEYALALNRTPFIYDNFPMELKN 240 QGKINKIAYSLFLNGPDAHFGSILFGAVDKSKYTGQLYTLPMLQAFNTLGSNPGMIITAQSVAILDSESGNKTVSDIQFP 320 VMLDSGTTFSYLPTEIAEAIGKSFDGEYSSDDQGYIFDCSKVNDTLLSVDFGGFNISANISNFVTSAKDRCVLNVKQSES 400 TYMLGDAFLVDAYVVYDLENYEISIAQASFNNQEEDIEVISDTVPGATPAPGYFSTWVYKPGSPIGTGDFINVSWTSYSE 480 FSQYKSLLATAAQSDDASSFSSSGGSSESTTKKQNAGYKYRSSFSFSLLSFISYFLL 560 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ................................................................................ 480 ......................................................... 560 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ YIR039C 29 SASSYVK|FP 0.075 . YIR039C 34 VKFPVQK|LA 0.074 . YIR039C 51 DVSTVFK|RN 0.072 . YIR039C 52 VSTVFKR|NE 0.121 . YIR039C 70 IGVYVVK|ME 0.067 . YIR039C 102 ADIAYCK|SM 0.090 . YIR039C 226 YALALNR|TP 0.068 . YIR039C 239 NFPMELK|NQ 0.061 . YIR039C 243 ELKNQGK|IN 0.066 . YIR039C 246 NQGKINK|IA 0.068 . YIR039C 270 LFGAVDK|SK 0.090 . YIR039C 272 GAVDKSK|YT 0.088 . YIR039C 312 DSESGNK|TV 0.083 . YIR039C 342 IAEAIGK|SF 0.080 . YIR039C 361 YIFDCSK|VN 0.059 . YIR039C 388 NFVTSAK|DR 0.066 . YIR039C 390 VTSAKDR|CV 0.154 . YIR039C 396 RCVLNVK|QS 0.059 . YIR039C 460 FSTWVYK|PG 0.076 . YIR039C 485 SEFSQYK|SL 0.082 . YIR039C 512 SSESTTK|KQ 0.063 . YIR039C 513 SESTTKK|QN 0.113 . YIR039C 519 KQNAGYK|YR 0.070 . YIR039C 521 NAGYKYR|SS 0.125 . ____________________________^_________________

Fasta :-
>YIR039C ATGCAATTGATTTCCATCCTCTCTTTGTTGTCATCATTGATGTGTTCATTGACCGTTTTA GGGTCTTCCGCAAGTTCCTATGTTAAGTTTCCTGTTCAAAAGTTGGCTGATATTATAAAT ATATGCACACAGGATGTTTCTACCGTCTTCAAAAGAAATGAGGTTCTTAACACCACAGTG ATAAATGGAATAGGAGTGTATGTTGTCAAGATGGAAATCGGAACGCCTCCACAAACGTTG TACCTACAGTTAGATACTGGCTCTTCAGATATGATTGTGAATAATGCTGACATTGCCTAT TGCAAATCGATGTCTGACGGATCTGACTACGCTTCAACTGATAATTACGAGCTCACAGCA ACGTTCAATGGGCTTCCTTCGACTACCATCTCATCAGAAGCTTATAACACTCTCTGCTCT TATTGGGGTACATTCGATGCAAGCAACTCATCTACTTTTGAGAATAATGCGACGTTTTTC AATAACACATACGGAGATGGTACGTATTATGCAGGGACTTATGGTACGGATGTTGTCTCT TTCGAAAATATTACTCTAAATGATTTCACTTTTGGTGTATCAAATGATACAATAGGCAAT CCAAGTGGCATTTTAGGCATATCGCTTCCCATTGCAGAATTTACAGATGGTATCGAATAC GCATTGGCATTGAACAGAACACCTTTCATATATGATAACTTTCCAATGGAATTAAAAAAT CAGGGAAAGATTAATAAAATAGCGTATTCTTTATTTTTGAATGGACCTGATGCACACTTC GGGAGCATCTTGTTTGGTGCAGTGGACAAAAGTAAGTACACAGGACAGCTTTACACCCTG CCTATGCTGCAGGCATTCAATACCCTTGGCTCAAATCCTGGGATGATTATTACTGCACAA AGTGTGGCAATTTTGGATAGTGAATCTGGCAATAAAACTGTTTCGGATATTCAATTTCCA GTGATGTTGGATTCTGGCACAACTTTCTCCTATTTACCCACCGAAATTGCAGAAGCAATC GGCAAAAGTTTTGACGGAGAGTACAGCTCTGACGACCAAGGCTACATCTTTGATTGTTCA AAAGTGAACGATACTTTACTGTCCGTCGACTTTGGAGGATTTAATATATCGGCAAACATA TCCAATTTCGTAACATCAGCTAAGGATCGTTGCGTTTTAAATGTTAAGCAATCCGAGTCC ACTTATATGCTGGGAGATGCTTTCCTTGTCGACGCATATGTAGTCTACGATTTAGAAAAC TACGAAATTTCTATTGCTCAGGCTAGCTTTAATAATCAAGAAGAAGATATTGAGGTTATC TCCGATACTGTCCCAGGTGCCACCCCTGCTCCCGGATACTTTAGTACATGGGTATATAAG CCCGGTAGTCCCATCGGAACAGGAGATTTTATTAATGTCAGCTGGACCTCGTATTCGGAA TTTTCACAGTACAAATCATTGCTTGCCACCGCAGCCCAAAGCGATGATGCTAGTTCTTTC TCAAGTAGTGGCGGCTCTAGCGAAAGCACCACTAAAAAACAAAATGCAGGTTACAAATAC CGTTCTTCTTTCTCCTTTTCATTATTGTCCTTCATATCTTATTTTCTTTTATAA
Download Fasta

Fasta :-

MQLISILSLLSSLMCSLTVLGSSASSYVKFPVQKLADIINICTQDVSTVFKRNEVLNTTV INGIGVYVVKMEIGTPPQTLYLQLDTGSSDMIVNNADIAYCKSMSDGSDYASTDNYELTA TFNGLPSTTISSEAYNTLCSYWGTFDASNSSTFENNATFFNNTYGDGTYYAGTYGTDVVS FENITLNDFTFGVSNDTIGNPSGILGISLPIAEFTDGIEYALALNRTPFIYDNFPMELKN QGKINKIAYSLFLNGPDAHFGSILFGAVDKSKYTGQLYTLPMLQAFNTLGSNPGMIITAQ SVAILDSESGNKTVSDIQFPVMLDSGTTFSYLPTEIAEAIGKSFDGEYSSDDQGYIFDCS KVNDTLLSVDFGGFNISANISNFVTSAKDRCVLNVKQSESTYMLGDAFLVDAYVVYDLEN YEISIAQASFNNQEEDIEVISDTVPGATPAPGYFSTWVYKPGSPIGTGDFINVSWTSYSE FSQYKSLLATAAQSDDASSFSSSGGSSESTTKKQNAGYKYRSSFSFSLLSFISYFLL

Pepsin-like

title: catalytic residue
coordinates: D85,D324

	ID	Site	Position	Gscore	Iscore
	YIR039C	T	456	0.532	0.038

	ID	Site	Position	Gscore	Iscore
	YIR039C	T	456	0.532	0.038

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YIR039C	386 S	NFVTSAKDR	0.996	unsp	YIR039C	506 S	SSGGSSEST	0.994	unsp

YIR039C | aspartyl protease

ID's

UniProt_ID: P40583

GEO Functions

Computed_GO_Component_IDs: GO:0031225 GO:0016020 GO:0005886

Computed_GO_Components: anchored component of membrane membrane plasma membrane

Computed_GO_Function_IDs: GO:0004190 GO:0016787 GO:0008233

Computed_GO_Functions: aspartic-type endopeptidase activity hydrolase activity peptidase activity

Computed_GO_Process_IDs: GO:0006508

Computed_GO_Processes: proteolysis

Curated_GO_Component_IDs: GO:0031362 GO:0005576 GO:0009277

Curated_GO_Components: anchored component of external side of plasma membrane extracellular region fungal-type cell wall

Curated_GO_Function_IDs: GO:0004190

Curated_GO_Functions: aspartic-type endopeptidase activity

Curated_GO_Processes: fungal-type cell wall organization protein catabolic process proteolysis

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Pepsin-like

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YIR039C

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India