YKL145W | proteasome regulatory particle base subunit RPT1

UniProt_ID: P33299

Computed_GO_Component_IDs: GO:0005737 GO:0005634 GO:0000502
Computed_GO_Components: cytoplasm nucleus proteasome complex
Computed_GO_Function_IDs: GO:0005524 GO:0016787 GO:0000166 GO:0036402
Computed_GO_Functions: ATP binding hydrolase activity nucleotide binding proteasome-activating ATPase activity
Computed_GO_Process_IDs: GO:1901800 GO:0030163
Computed_GO_Processes: positive regulation of proteasomal protein catabolic process protein catabolic process
Curated_GO_Component_IDs: GO:0031597 GO:0031595 GO:0008540
Curated_GO_Components: cytosolic proteasome complex nuclear proteasome complex proteasome regulatory particle, base subcomplex
Curated_GO_Function_IDs: GO:0016887 GO:0017025 GO:0036402 GO:0031625
Curated_GO_Functions: ATPase activity TBP-class protein binding proteasome-activating ATPase activity ubiquitin protein ligase binding
Curated_GO_Processes: positive regulation of RNA polymerase II transcriptional preinitiation complex assembly positive regulation of protein catabolic process proteasome regulatory particle assembly ubiquitin-dependent ERAD pathway ubiquitin-dependent protein catabolic process

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YKL145W	OTHER	0.999996	0.000001	0.000002

No Results

Fasta :-
>YKL145W MPPKEDWEKYKAPLEDDDKKPDDDKIVPLTEGDIQVLKSYGAAPYAAKLKQTENDLKDIE ARIKEKAGVKESDTGLAPSHLWDIMGDRQRLGEEHPLQVARCTKIIKGNGESDETTTDNN NSGNSNSNSNQQSTDADEDDEDAKYVINLKQIAKFVVGLGERVSPTDIEEGMRVGVDRSK YNIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQIEKLREVVELPLLSPERFATLGI DPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELITQLDGFDPRGNIKVMFATNRPNT LDPALLRPGRIDRKVEFSLPDLEGRANIFRIHSKSMSVERGIRWELISRLCPNSTGAELR SVCTEAGMFAIRARRKVATEKDFLKAVDKVISGYKKFSSTSRYMQYN
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YKL145W.fa Sequence name : YKL145W Sequence length : 467 VALUES OF COMPUTED PARAMETERS Coef20 : 2.095 CoefTot : -0.619 ChDiff : -9 ZoneTo : 4 KR : 1 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 0.282 1.071 -0.091 0.443 MesoH : -0.989 0.215 -0.404 0.135 MuHd_075 : 4.993 2.148 0.693 1.369 MuHd_095 : 10.035 2.151 3.224 2.338 MuHd_100 : 12.226 2.856 4.117 2.350 MuHd_105 : 16.634 4.681 4.948 2.524 Hmax_075 : -14.500 -7.117 -6.706 0.150 Hmax_095 : -20.650 -10.587 -7.022 -0.254 Hmax_100 : -14.800 -8.600 -5.722 0.610 Hmax_105 : -6.533 -5.950 -4.483 1.762 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9989 0.0011 DFMC : 0.9983 0.0017

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 467 YKL145W MPPKEDWEKYKAPLEDDDKKPDDDKIVPLTEGDIQVLKSYGAAPYAAKLKQTENDLKDIEARIKEKAGVKESDTGLAPSH 80 LWDIMGDRQRLGEEHPLQVARCTKIIKGNGESDETTTDNNNSGNSNSNSNQQSTDADEDDEDAKYVINLKQIAKFVVGLG 160 ERVSPTDIEEGMRVGVDRSKYNIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQIEKLREVVELPLLSPERFATLGI 240 DPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFD 320 DGAGGDNEVQRTMLELITQLDGFDPRGNIKVMFATNRPNTLDPALLRPGRIDRKVEFSLPDLEGRANIFRIHSKSMSVER 400 GIRWELISRLCPNSTGAELRSVCTEAGMFAIRARRKVATEKDFLKAVDKVISGYKKFSSTSRYMQYN 480 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ....................................................P........................... 400 ..................................P................................ 480 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 2 Name Pos Context Score Pred ____________________________v_________________ YKL145W 4 ---MPPK|ED 0.064 . YKL145W 9 PKEDWEK|YK 0.069 . YKL145W 11 EDWEKYK|AP 0.064 . YKL145W 19 PLEDDDK|KP 0.055 . YKL145W 20 LEDDDKK|PD 0.099 . YKL145W 25 KKPDDDK|IV 0.068 . YKL145W 38 GDIQVLK|SY 0.098 . YKL145W 48 AAPYAAK|LK 0.062 . YKL145W 50 PYAAKLK|QT 0.076 . YKL145W 57 QTENDLK|DI 0.078 . YKL145W 62 LKDIEAR|IK 0.121 . YKL145W 64 DIEARIK|EK 0.061 . YKL145W 66 EARIKEK|AG 0.067 . YKL145W 70 KEKAGVK|ES 0.067 . YKL145W 88 WDIMGDR|QR 0.081 . YKL145W 90 IMGDRQR|LG 0.088 . YKL145W 101 HPLQVAR|CT 0.120 . YKL145W 104 QVARCTK|II 0.154 . YKL145W 107 RCTKIIK|GN 0.074 . YKL145W 144 EDDEDAK|YV 0.072 . YKL145W 150 KYVINLK|QI 0.060 . YKL145W 154 NLKQIAK|FV 0.083 . YKL145W 162 VVGLGER|VS 0.062 . YKL145W 173 DIEEGMR|VG 0.060 . YKL145W 178 MRVGVDR|SK 0.204 . YKL145W 180 VGVDRSK|YN 0.060 . YKL145W 190 ELPLPPR|ID 0.076 . YKL145W 203 MMTVEEK|PD 0.058 . YKL145W 215 SDVGGCK|DQ 0.072 . YKL145W 220 CKDQIEK|LR 0.059 . YKL145W 222 DQIEKLR|EV 0.099 . YKL145W 234 PLLSPER|FA 0.100 . YKL145W 244 LGIDPPK|GI 0.069 . YKL145W 256 GPPGTGK|TL 0.063 . YKL145W 261 GKTLCAR|AV 0.108 . YKL145W 266 ARAVANR|TD 0.095 . YKL145W 273 TDATFIR|VI 0.156 . YKL145W 282 GSELVQK|YV 0.132 . YKL145W 289 YVGEGAR|MV 0.137 . YKL145W 292 EGARMVR|EL 0.241 . YKL145W 299 ELFEMAR|TK 0.085 . YKL145W 301 FEMARTK|KA 0.081 . YKL145W 302 EMARTKK|AC 0.304 . YKL145W 318 DAVGGAR|FD 0.110 . YKL145W 331 GDNEVQR|TM 0.107 . YKL145W 346 LDGFDPR|GN 0.121 . YKL145W 350 DPRGNIK|VM 0.062 . YKL145W 357 VMFATNR|PN 0.075 . YKL145W 367 LDPALLR|PG 0.073 . YKL145W 370 ALLRPGR|ID 0.282 . YKL145W 373 RPGRIDR|KV 0.558 *ProP* YKL145W 374 PGRIDRK|VE 0.066 . YKL145W 385 LPDLEGR|AN 0.089 . YKL145W 390 GRANIFR|IH 0.131 . YKL145W 394 IFRIHSK|SM 0.103 . YKL145W 400 KSMSVER|GI 0.150 . YKL145W 403 SVERGIR|WE 0.150 . YKL145W 409 RWELISR|LC 0.068 . YKL145W 420 STGAELR|SV 0.298 . YKL145W 432 AGMFAIR|AR 0.087 . YKL145W 434 MFAIRAR|RK 0.112 . YKL145W 435 FAIRARR|KV 0.513 *ProP* YKL145W 436 AIRARRK|VA 0.096 . YKL145W 441 RKVATEK|DF 0.076 . YKL145W 445 TEKDFLK|AV 0.108 . YKL145W 449 FLKAVDK|VI 0.069 . YKL145W 455 KVISGYK|KF 0.056 . YKL145W 456 VISGYKK|FS 0.185 . YKL145W 462 KFSSTSR|YM 0.102 . ____________________________^_________________

Fasta :-
>YKL145W ATGCCACCAAAAGAAGACTGGGAAAAATACAAGGCACCTTTGGAAGACGATGATAAAAAA CCTGATGATGACAAGATCGTACCCTTAACAGAAGGTGACATTCAAGTCTTAAAATCATAC GGTGCAGCTCCATACGCAGCCAAATTAAAGCAAACTGAGAATGACTTAAAAGACATTGAA GCGAGAATCAAAGAAAAGGCCGGTGTGAAAGAAAGCGATACAGGGTTAGCACCCTCCCAT CTATGGGATATTATGGGTGATAGGCAGAGACTGGGCGAAGAACATCCCTTACAAGTCGCT CGTTGCACGAAGATCATTAAGGGGAATGGTGAAAGTGACGAAACTACGACAGATAATAAT AACAGCGGCAATAGCAATAGTAATAGCAATCAACAGTCTACTGATGCAGACGAAGACGAT GAAGATGCCAAGTACGTGATAAATCTTAAGCAAATTGCCAAATTTGTCGTCGGATTAGGT GAACGTGTTTCTCCAACAGATATAGAAGAAGGTATGCGTGTAGGTGTCGATAGGTCGAAA TATAATATTGAACTTCCATTGCCTCCAAGGATTGACCCATCAGTTACTATGATGACCGTT GAAGAAAAGCCTGACGTTACTTATAGCGATGTCGGTGGCTGTAAAGACCAAATTGAAAAG CTGAGAGAAGTTGTCGAGCTGCCCTTATTATCTCCAGAAAGATTTGCTACTCTTGGTATT GATCCACCAAAGGGTATCTTATTATATGGGCCACCTGGTACTGGTAAGACATTATGTGCT CGTGCTGTTGCTAATAGAACTGATGCAACTTTTATTAGGGTCATTGGGTCTGAGCTAGTG CAAAAATATGTCGGTGAAGGTGCTCGTATGGTTAGAGAATTATTTGAAATGGCTCGTACC AAAAAGGCTTGCATTATATTCTTCGATGAAATCGACGCTGTTGGTGGTGCTCGTTTTGAT GATGGTGCTGGTGGTGATAATGAAGTTCAAAGAACTATGTTAGAACTGATTACACAGTTA GACGGGTTTGACCCTCGTGGTAACATTAAAGTGATGTTTGCCACCAATAGGCCCAACACT TTAGATCCAGCTTTATTGAGACCCGGTAGAATTGATCGTAAGGTAGAGTTTTCATTACCT GACTTGGAAGGTCGTGCAAATATCTTCCGTATTCACTCTAAATCAATGAGTGTGGAACGT GGCATCAGATGGGAACTTATCTCCAGACTGTGTCCAAACTCTACCGGTGCAGAATTAAGA TCTGTTTGCACAGAAGCCGGTATGTTTGCCATTAGAGCAAGAAGAAAGGTGGCTACTGAA AAGGATTTCCTGAAGGCTGTTGATAAAGTTATTAGCGGATACAAGAAGTTTAGTTCCACA TCGCGTTATATGCAATATAATTGA
Download Fasta

Fasta :-

MPPKEDWEKYKAPLEDDDKKPDDDKIVPLTEGDIQVLKSYGAAPYAAKLKQTENDLKDIE ARIKEKAGVKESDTGLAPSHLWDIMGDRQRLGEEHPLQVARCTKIIKGNGESDETTTDNN NSGNSNSNSNQQSTDADEDDEDAKYVINLKQIAKFVVGLGERVSPTDIEEGMRVGVDRSK YNIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQIEKLREVVELPLLSPERFATLGI DPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMART KKACIIFFDEIDAVGGARFDDGAGGDNEVQRTMLELITQLDGFDPRGNIKVMFATNRPNT LDPALLRPGRIDRKVEFSLPDLEGRANIFRIHSKSMSVERGIRWELISRLCPNSTGAELR SVCTEAGMFAIRARRKVATEKDFLKAVDKVISGYKKFSSTSRYMQYN

CATH

title: ATP binding site
coordinates: P251,P252,G253,T254,G255,K256,T257,L258,D309,N356

No Results

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YKL145W	397 S	SKSMSVERG	0.994	unsp	YKL145W	397 S	SKSMSVERG	0.994	unsp	YKL145W	397 S	SKSMSVERG	0.994	unsp	YKL145W	164 S	GERVSPTDI	0.998	unsp	YKL145W	378 S	KVEFSLPDL	0.993	unsp

YKL145W | proteasome regulatory particle base subunit RPT1

ID's

UniProt_ID: P33299

GEO Functions

Computed_GO_Component_IDs: GO:0005737 GO:0005634 GO:0000502

Computed_GO_Components: cytoplasm nucleus proteasome complex

Computed_GO_Function_IDs: GO:0005524 GO:0016787 GO:0000166 GO:0036402

Computed_GO_Functions: ATP binding hydrolase activity nucleotide binding proteasome-activating ATPase activity

Computed_GO_Process_IDs: GO:1901800 GO:0030163

Computed_GO_Processes: positive regulation of proteasomal protein catabolic process protein catabolic process

Curated_GO_Component_IDs: GO:0031597 GO:0031595 GO:0008540

Curated_GO_Components: cytosolic proteasome complex nuclear proteasome complex proteasome regulatory particle, base subcomplex

Curated_GO_Function_IDs: GO:0016887 GO:0017025 GO:0036402 GO:0031625

Curated_GO_Functions: ATPase activity TBP-class protein binding proteasome-activating ATPase activity ubiquitin protein ligase binding

Curated_GO_Processes: positive regulation of RNA polymerase II transcriptional preinitiation complex assembly positive regulation of protein catabolic process proteasome regulatory particle assembly ubiquitin-dependent ERAD pathway ubiquitin-dependent protein catabolic process

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

CATH

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YKL145W

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India