YLR244C | methionine aminopeptidase MAP1

UniProt_ID: Q01662

Computed_GO_Component_IDs: GO:0005737
Computed_GO_Components: cytoplasm
Computed_GO_Function_IDs: GO:0004177 GO:0016787 GO:0046872 GO:0008235 GO:0008233
Computed_GO_Functions: aminopeptidase activity hydrolase activity metal ion binding metalloexopeptidase activity peptidase activity
Computed_GO_Process_IDs: GO:0006508
Computed_GO_Processes: proteolysis
Curated_GO_Component_IDs: GO:0010494 GO:0022626
Curated_GO_Components: cytoplasmic stress granule cytosolic ribosome
Curated_GO_Function_IDs: GO:0003729 GO:0070006
Curated_GO_Functions: mRNA binding metalloaminopeptidase activity
Curated_GO_Processes: negative regulation of gene expression protein initiator methionine removal involved in protein maturation

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YLR244C	OTHER	0.999940	0.000054	0.000006

No Results

Fasta :-
>YLR244C MSTATTTVTTSDQASHPTKIYCSGLQCGRETSSQMKCPVCLKQGIVSIFCDTSCYENNYK AHKALHNAKDGLEGAYDPFPKFKYSGKVKASYPLTPRRYVPEDIPKPDWAANGLPVSEQR NDRLNNIPIYKKDQIKKIRKACMLGREVLDIAAAHVRPGITTDELDEIVHNETIKRGAYP SPLNYYNFPKSLCTSVNEVICHGVPDKTVLKEGDIVNLDVSLYYQGYHADLNETYYVGEN ISKEALNTTETSRECLKLAIKMCKPGTTFQELGDHIEKHATENKCSVVRTYCGHGVGEFF HCSPNIPHYAKNRTPGVMKPGMVFTIEPMINEGTWKDMTWPDDWTSTTQDGKLSAQFEHT LLVTEHGVEILTARNKKSPGGPRQRIK
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YLR244C.fa Sequence name : YLR244C Sequence length : 387 VALUES OF COMPUTED PARAMETERS Coef20 : 4.229 CoefTot : -1.637 ChDiff : 3 ZoneTo : 50 KR : 4 DE : 2 CleavSite : 31 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 0.712 0.976 0.129 0.418 MesoH : -0.888 -0.080 -0.477 0.109 MuHd_075 : 24.340 18.420 8.713 5.158 MuHd_095 : 28.193 15.194 7.562 6.300 MuHd_100 : 34.100 15.363 8.664 7.328 MuHd_105 : 36.958 16.807 10.762 7.839 Hmax_075 : 8.000 12.300 4.026 3.120 Hmax_095 : 12.300 7.300 3.031 4.180 Hmax_100 : 11.000 6.100 2.764 3.500 Hmax_105 : 8.500 5.100 2.527 3.650 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.8206 0.1794 DFMC : 0.7918 0.2082

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 387 YLR244C MSTATTTVTTSDQASHPTKIYCSGLQCGRETSSQMKCPVCLKQGIVSIFCDTSCYENNYKAHKALHNAKDGLEGAYDPFP 80 KFKYSGKVKASYPLTPRRYVPEDIPKPDWAANGLPVSEQRNDRLNNIPIYKKDQIKKIRKACMLGREVLDIAAAHVRPGI 160 TTDELDEIVHNETIKRGAYPSPLNYYNFPKSLCTSVNEVICHGVPDKTVLKEGDIVNLDVSLYYQGYHADLNETYYVGEN 240 ISKEALNTTETSRECLKLAIKMCKPGTTFQELGDHIEKHATENKCSVVRTYCGHGVGEFFHCSPNIPHYAKNRTPGVMKP 320 GMVFTIEPMINEGTWKDMTWPDDWTSTTQDGKLSAQFEHTLLVTEHGVEILTARNKKSPGGPRQRIK 400 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ........................................................P.......... 400 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 1 Name Pos Context Score Pred ____________________________v_________________ YLR244C 19 QASHPTK|IY 0.092 . YLR244C 29 SGLQCGR|ET 0.087 . YLR244C 36 ETSSQMK|CP 0.061 . YLR244C 42 KCPVCLK|QG 0.057 . YLR244C 60 CYENNYK|AH 0.057 . YLR244C 63 NNYKAHK|AL 0.075 . YLR244C 69 KALHNAK|DG 0.069 . YLR244C 81 AYDPFPK|FK 0.066 . YLR244C 83 DPFPKFK|YS 0.107 . YLR244C 87 KFKYSGK|VK 0.061 . YLR244C 89 KYSGKVK|AS 0.075 . YLR244C 97 SYPLTPR|RY 0.067 . YLR244C 98 YPLTPRR|YV 0.184 . YLR244C 106 VPEDIPK|PD 0.066 . YLR244C 120 LPVSEQR|ND 0.073 . YLR244C 123 SEQRNDR|LN 0.163 . YLR244C 131 NNIPIYK|KD 0.058 . YLR244C 132 NIPIYKK|DQ 0.104 . YLR244C 136 YKKDQIK|KI 0.072 . YLR244C 137 KKDQIKK|IR 0.090 . YLR244C 139 DQIKKIR|KA 0.118 . YLR244C 140 QIKKIRK|AC 0.084 . YLR244C 146 KACMLGR|EV 0.131 . YLR244C 157 IAAAHVR|PG 0.084 . YLR244C 175 VHNETIK|RG 0.056 . YLR244C 176 HNETIKR|GA 0.249 . YLR244C 190 NYYNFPK|SL 0.105 . YLR244C 207 CHGVPDK|TV 0.082 . YLR244C 211 PDKTVLK|EG 0.061 . YLR244C 243 VGENISK|EA 0.060 . YLR244C 253 NTTETSR|EC 0.064 . YLR244C 257 TSRECLK|LA 0.066 . YLR244C 261 CLKLAIK|MC 0.061 . YLR244C 264 LAIKMCK|PG 0.066 . YLR244C 278 LGDHIEK|HA 0.064 . YLR244C 284 KHATENK|CS 0.058 . YLR244C 289 NKCSVVR|TY 0.098 . YLR244C 311 NIPHYAK|NR 0.067 . YLR244C 313 PHYAKNR|TP 0.111 . YLR244C 319 RTPGVMK|PG 0.060 . YLR244C 336 INEGTWK|DM 0.072 . YLR244C 352 STTQDGK|LS 0.067 . YLR244C 374 VEILTAR|NK 0.072 . YLR244C 376 ILTARNK|KS 0.061 . YLR244C 377 LTARNKK|SP 0.543 *ProP* YLR244C 383 KSPGGPR|QR 0.090 . YLR244C 385 PGGPRQR|IK 0.086 . YLR244C 387 GPRQRIK|-- 0.084 . ____________________________^_________________

Fasta :-
>YLR244C ATGAGCACTGCAACTACAACAGTTACTACCTCCGATCAGGCTTCTCATCCTACCAAGATA TATTGCTCCGGTTTGCAATGTGGTAGAGAAACTTCGTCCCAAATGAAATGCCCTGTTTGT CTAAAACAAGGCATCGTTTCCATTTTCTGCGACACAAGCTGTTATGAAAACAACTACAAA GCTCACAAAGCTTTGCACAATGCTAAGGACGGCTTGGAAGGTGCTTATGATCCTTTCCCA AAATTCAAATATTCTGGTAAAGTGAAGGCTTCATATCCACTTACCCCAAGAAGGTATGTC CCTGAAGATATTCCTAAACCGGACTGGGCCGCTAATGGGCTACCAGTCAGTGAACAAAGA AATGATAGACTTAACAACATCCCTATATACAAGAAAGATCAAATTAAGAAGATTAGAAAG GCATGTATGTTGGGTAGAGAAGTTCTTGATATTGCCGCTGCCCATGTCAGACCAGGCATC ACTACAGATGAATTAGATGAAATCGTCCACAATGAAACAATTAAGAGAGGTGCCTACCCT TCCCCTCTTAATTATTACAACTTTCCTAAATCGCTTTGTACCTCTGTCAATGAAGTTATT TGTCACGGTGTGCCCGATAAAACTGTCTTGAAGGAAGGTGATATTGTCAATTTAGATGTT TCCTTATACTACCAAGGTTATCATGCAGACTTGAATGAGACATATTATGTCGGCGAAAAC ATTTCTAAGGAAGCTCTTAATACTACTGAGACCTCAAGAGAATGTTTGAAACTAGCCATT AAAATGTGTAAGCCAGGTACCACCTTCCAAGAGTTAGGTGATCATATTGAAAAACACGCT ACCGAAAATAAGTGCAGTGTAGTAAGAACTTATTGTGGACATGGTGTTGGTGAATTTTTC CATTGTTCCCCAAATATTCCCCACTACGCCAAGAATAGAACACCTGGTGTTATGAAACCA GGTATGGTTTTCACCATCGAACCTATGATTAATGAAGGTACTTGGAAGGATATGACCTGG CCTGATGACTGGACTTCTACCACCCAAGACGGTAAACTGAGTGCTCAATTTGAACATACA CTGTTGGTTACCGAACATGGTGTTGAAATCCTAACAGCCAGGAATAAGAAATCACCAGGT GGCCCAAGACAGAGAATTAAATAG
Download Fasta

Fasta :-

MSTATTTVTTSDQASHPTKIYCSGLQCGRETSSQMKCPVCLKQGIVSIFCDTSCYENNYK AHKALHNAKDGLEGAYDPFPKFKYSGKVKASYPLTPRRYVPEDIPKPDWAANGLPVSEQR NDRLNNIPIYKKDQIKKIRKACMLGREVLDIAAAHVRPGITTDELDEIVHNETIKRGAYP SPLNYYNFPKSLCTSVNEVICHGVPDKTVLKEGDIVNLDVSLYYQGYHADLNETYYVGEN ISKEALNTTETSRECLKLAIKMCKPGTTFQELGDHIEKHATENKCSVVRTYCGHGVGEFF HCSPNIPHYAKNRTPGVMKPGMVFTIEPMINEGTWKDMTWPDDWTSTTQDGKLSAQFEHT LLVTEHGVEILTARNKKSPGGPRQRIK

Creatinase/aminopeptidase

title: active site
coordinates: H202,D219,D230,H294,E327,E358

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	YLR244C	T	3	0.710	0.051	YLR244C	T	5	0.673	0.045	YLR244C	T	6	0.644	0.133	YLR244C	S	2	0.625	0.064	YLR244C	T	7	0.616	0.049	YLR244C	T	9	0.591	0.078	YLR244C	T	10	0.549	0.045

	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore	ID	Site	Position	Gscore	Iscore
	YLR244C	T	3	0.710	0.051	YLR244C	T	5	0.673	0.045	YLR244C	T	6	0.644	0.133	YLR244C	S	2	0.625	0.064	YLR244C	T	7	0.616	0.049	YLR244C	T	9	0.591	0.078	YLR244C	T	10	0.549	0.045

	ID	Site	Peptide	Score	Method
	YLR244C	378 S	RNKKSPGGP	0.99	unsp

YLR244C | methionine aminopeptidase MAP1

ID's

UniProt_ID: Q01662

GEO Functions

Computed_GO_Component_IDs: GO:0005737

Computed_GO_Components: cytoplasm

Computed_GO_Function_IDs: GO:0004177 GO:0016787 GO:0046872 GO:0008235 GO:0008233

Computed_GO_Functions: aminopeptidase activity hydrolase activity metal ion binding metalloexopeptidase activity peptidase activity

Computed_GO_Process_IDs: GO:0006508

Computed_GO_Processes: proteolysis

Curated_GO_Component_IDs: GO:0010494 GO:0022626

Curated_GO_Components: cytoplasmic stress granule cytosolic ribosome

Curated_GO_Function_IDs: GO:0003729 GO:0070006

Curated_GO_Functions: mRNA binding metalloaminopeptidase activity

Curated_GO_Processes: negative regulation of gene expression protein initiator methionine removal involved in protein maturation

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

Creatinase/aminopeptidase

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YLR244C

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India