YOR259C | proteasome regulatory particle base subunit RPT4

UniProt_ID: P53549

Computed_GO_Component_IDs: GO:0005737 GO:0000502
Computed_GO_Components: cytoplasm proteasome complex
Computed_GO_Function_IDs: GO:0005524 GO:0016787 GO:0000166
Computed_GO_Functions: ATP binding hydrolase activity nucleotide binding
Computed_GO_Process_IDs: GO:0030163
Computed_GO_Processes: protein catabolic process
Curated_GO_Component_IDs: GO:0031597 GO:0031595 GO:0005634 GO:0008540
Curated_GO_Components: cytosolic proteasome complex nuclear proteasome complex nucleus proteasome regulatory particle, base subcomplex
Curated_GO_Function_IDs: GO:0016887 GO:0017025 GO:0036402 GO:0019904 GO:0031625
Curated_GO_Functions: ATPase activity TBP-class protein binding proteasome-activating ATPase activity protein domain specific binding ubiquitin protein ligase binding
Curated_GO_Processes: nucleotide-excision repair positive regulation of RNA polymerase II transcriptional preinitiation complex assembly positive regulation of transcription elongation from RNA polymerase II promoter proteasome regulatory particle assembly ubiquitin-dependent ERAD pathway

	_ID	Prediction	OTHER	SP	mTP	CS_Position
	YOR259C	OTHER	0.999882	0.000002	0.000116

No Results

Fasta :-
>YOR259C MSEEQDPLLAGLGETSGDNHTQQSHEQQPEQPQETEEHHEEEPSRVDPEQEAHNKALNQF KRKLLEHRRYDDQLKQRRQNIRDLEKLYDKTENDIKALQSIGQLIGEVMKELSEEKYIVK ASSGPRYIVGVRNSVDRSKLKKGVRVTLDITTLTIMRILPRETDPLVYNMTSFEQGEITF DGIGGLTEQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGKTLLAKAVAATIG ANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIGGRRFSEGTSADRE IQRTLMELLTQMDGFDNLGQTKIIMATNRPDTLDPALLRPGRLDRKVEIPLPNEAGRLEI FKIHTAKVKKTGEFDFEAAVKMSDGFNGADIRNCATEAGFFAIRDDRDHINPDDLMKAVR KVAEVKKLEGTIEYQKL
Download Fasta

MitoProt II - v1.101 File : /home/rajan/sadaf/4480_mitoprot/test/YOR259C.fa Sequence name : YOR259C Sequence length : 437 VALUES OF COMPUTED PARAMETERS Coef20 : 2.521 CoefTot : 0.112 ChDiff : -11 ZoneTo : 2 KR : 0 DE : 0 CleavSite : 0 HYDROPHOBIC SCALE USED GES KD GVH1 ECS H17 : 1.476 1.541 0.183 0.592 MesoH : -0.475 0.410 -0.323 0.267 MuHd_075 : 20.002 4.095 4.800 2.100 MuHd_095 : 31.638 17.447 7.237 4.087 MuHd_100 : 29.863 16.256 6.933 3.230 MuHd_105 : 19.469 11.828 4.909 1.664 Hmax_075 : 0.000 0.900 -1.446 2.360 Hmax_095 : 9.012 7.175 0.343 3.386 Hmax_100 : 9.500 8.300 -0.011 2.860 Hmax_105 : 9.500 8.300 -0.011 2.860 CLASS NOT-MITO MITO(/CHLORO) DFM : 0.9896 0.0104 DFMC : 0.9771 0.0229

##### ProP v.1.0b ProPeptide Cleavage Site Prediction ##### ##### Furin-type cleavage site prediction (Arginine/Lysine residues) ##### 437 YOR259C MSEEQDPLLAGLGETSGDNHTQQSHEQQPEQPQETEEHHEEEPSRVDPEQEAHNKALNQFKRKLLEHRRYDDQLKQRRQN 80 IRDLEKLYDKTENDIKALQSIGQLIGEVMKELSEEKYIVKASSGPRYIVGVRNSVDRSKLKKGVRVTLDITTLTIMRILP 160 RETDPLVYNMTSFEQGEITFDGIGGLTEQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGKTLLAKAVAATIG 240 ANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIGGRRFSEGTSADREIQRTLMELLTQMDGFDNLGQ 320 TKIIMATNRPDTLDPALLRPGRLDRKVEIPLPNEAGRLEIFKIHTAKVKKTGEFDFEAAVKMSDGFNGADIRNCATEAGF 400 FAIRDDRDHINPDDLMKAVRKVAEVKKLEGTIEYQKL 480 ................................................................................ 80 ................................................................................ 160 ................................................................................ 240 ................................................................................ 320 ................................................................................ 400 ..................................... 480 Propeptide cleavage sites predicted: Arg(R)/Lys(K): 0 Name Pos Context Score Pred ____________________________v_________________ YOR259C 45 HEEEPSR|VD 0.091 . YOR259C 55 EQEAHNK|AL 0.068 . YOR259C 61 KALNQFK|RK 0.056 . YOR259C 62 ALNQFKR|KL 0.205 . YOR259C 63 LNQFKRK|LL 0.099 . YOR259C 68 RKLLEHR|RY 0.111 . YOR259C 69 KLLEHRR|YD 0.132 . YOR259C 75 RYDDQLK|QR 0.064 . YOR259C 77 DDQLKQR|RQ 0.073 . YOR259C 78 DQLKQRR|QN 0.113 . YOR259C 82 QRRQNIR|DL 0.170 . YOR259C 86 NIRDLEK|LY 0.068 . YOR259C 90 LEKLYDK|TE 0.056 . YOR259C 96 KTENDIK|AL 0.064 . YOR259C 110 LIGEVMK|EL 0.069 . YOR259C 116 KELSEEK|YI 0.061 . YOR259C 120 EEKYIVK|AS 0.061 . YOR259C 126 KASSGPR|YI 0.143 . YOR259C 132 RYIVGVR|NS 0.063 . YOR259C 137 VRNSVDR|SK 0.187 . YOR259C 139 NSVDRSK|LK 0.067 . YOR259C 141 VDRSKLK|KG 0.061 . YOR259C 142 DRSKLKK|GV 0.259 . YOR259C 145 KLKKGVR|VT 0.083 . YOR259C 157 TTLTIMR|IL 0.071 . YOR259C 161 IMRILPR|ET 0.108 . YOR259C 191 GLTEQIR|EL 0.096 . YOR259C 194 EQIRELR|EV 0.220 . YOR259C 202 VIELPLK|NP 0.056 . YOR259C 209 NPEIFQR|VG 0.086 . YOR259C 213 FQRVGIK|PP 0.066 . YOR259C 216 VGIKPPK|GV 0.078 . YOR259C 228 GPPGTGK|TL 0.062 . YOR259C 233 GKTLLAK|AV 0.081 . YOR259C 254 ASGIVDK|YI 0.099 . YOR259C 261 YIGESAR|II 0.111 . YOR259C 264 ESARIIR|EM 0.261 . YOR259C 271 EMFAYAK|EH 0.064 . YOR259C 289 VDAIGGR|RF 0.086 . YOR259C 290 DAIGGRR|FS 0.126 . YOR259C 299 EGTSADR|EI 0.074 . YOR259C 303 ADREIQR|TL 0.110 . YOR259C 322 DNLGQTK|II 0.062 . YOR259C 329 IIMATNR|PD 0.078 . YOR259C 339 LDPALLR|PG 0.069 . YOR259C 342 ALLRPGR|LD 0.208 . YOR259C 345 RPGRLDR|KV 0.485 . YOR259C 346 PGRLDRK|VE 0.066 . YOR259C 357 LPNEAGR|LE 0.113 . YOR259C 362 GRLEIFK|IH 0.066 . YOR259C 367 FKIHTAK|VK 0.086 . YOR259C 369 IHTAKVK|KT 0.072 . YOR259C 370 HTAKVKK|TG 0.101 . YOR259C 381 DFEAAVK|MS 0.060 . YOR259C 392 FNGADIR|NC 0.078 . YOR259C 404 AGFFAIR|DD 0.090 . YOR259C 407 FAIRDDR|DH 0.187 . YOR259C 417 NPDDLMK|AV 0.083 . YOR259C 420 DLMKAVR|KV 0.118 . YOR259C 421 LMKAVRK|VA 0.099 . YOR259C 426 RKVAEVK|KL 0.070 . YOR259C 427 KVAEVKK|LE 0.137 . YOR259C 436 GTIEYQK|L- 0.057 . ____________________________^_________________

Fasta :-
>YOR259C ATGAGTGAAGAACAGGACCCTTTATTAGCAGGATTGGGGGAAACGTCCGGCGACAATCAC ACCCAACAGTCACACGAACAACAACCAGAACAACCACAGGAAACGGAAGAACATCATGAA GAGGAGCCTTCTAGAGTGGATCCTGAACAGGAGGCCCATAACAAGGCCTTGAATCAATTC AAGAGAAAGCTGCTAGAACACAGAAGGTATGATGATCAATTGAAGCAGCGCCGTCAAAAT ATACGAGATCTAGAGAAGTTATATGACAAGACTGAAAACGACATAAAAGCTTTGCAAAGT ATTGGACAATTGATTGGCGAAGTCATGAAGGAATTATCTGAAGAGAAATATATAGTGAAG GCCTCTTCGGGCCCACGTTATATTGTCGGAGTTAGGAATTCGGTAGATCGCTCTAAATTA AAGAAAGGGGTGAGAGTCACCTTAGATATCACCACTTTGACTATAATGAGAATTTTGCCC AGAGAGACAGATCCACTGGTGTATAATATGACCAGTTTTGAACAAGGTGAAATCACTTTT GATGGTATTGGTGGTTTGACTGAGCAAATCAGAGAATTAAGGGAGGTTATAGAATTACCA TTGAAGAACCCAGAAATTTTCCAGAGGGTCGGTATCAAACCTCCAAAGGGTGTGCTACTA TATGGTCCCCCTGGTACTGGTAAAACTTTACTAGCGAAGGCAGTTGCTGCTACGATTGGA GCCAACTTCATTTTCTCTCCAGCGTCTGGTATTGTGGATAAATACATTGGTGAGTCTGCT CGTATTATTAGAGAAATGTTTGCATATGCAAAGGAACACGAACCTTGCATCATTTTTATG GATGAAGTGGATGCTATTGGTGGTAGAAGATTCAGTGAAGGTACTTCAGCAGACCGTGAA ATTCAACGTACGTTGATGGAGTTGTTGACCCAGATGGATGGTTTTGATAATCTTGGACAG ACTAAAATCATCATGGCTACGAATAGACCAGATACTTTAGATCCTGCTTTGTTGAGGCCC GGTAGACTAGACAGGAAAGTTGAAATCCCATTGCCAAATGAGGCCGGCAGATTAGAAATT TTCAAAATTCATACTGCAAAAGTCAAAAAAACAGGGGAATTTGACTTCGAGGCTGCTGTA AAAATGAGTGATGGTTTCAATGGTGCTGATATTCGTAACTGTGCAACTGAAGCAGGTTTT TTCGCCATAAGAGATGACCGTGATCACATCAACCCTGATGATTTAATGAAAGCCGTAAGA AAAGTAGCTGAAGTTAAGAAATTGGAAGGCACTATAGAATACCAAAAATTATGA
Download Fasta

Fasta :-

MSEEQDPLLAGLGETSGDNHTQQSHEQQPEQPQETEEHHEEEPSRVDPEQEAHNKALNQF KRKLLEHRRYDDQLKQRRQNIRDLEKLYDKTENDIKALQSIGQLIGEVMKELSEEKYIVK ASSGPRYIVGVRNSVDRSKLKKGVRVTLDITTLTIMRILPRETDPLVYNMTSFEQGEITF DGIGGLTEQIRELREVIELPLKNPEIFQRVGIKPPKGVLLYGPPGTGKTLLAKAVAATIG ANFIFSPASGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIGGRRFSEGTSADRE IQRTLMELLTQMDGFDNLGQTKIIMATNRPDTLDPALLRPGRLDRKVEIPLPNEAGRLEI FKIHTAKVKKTGEFDFEAAVKMSDGFNGADIRNCATEAGFFAIRDDRDHINPDDLMKAVR KVAEVKKLEGTIEYQKL

CATH

title: ATP binding site
coordinates: P223,P224,G225,T226,G227,K228,T229,L230,D281,N328

	ID	Site	Position	Gscore	Iscore
	YOR259C	T	35	0.577	0.120

	ID	Site	Position	Gscore	Iscore
	YOR259C	T	35	0.577	0.120

	ID	Site	Peptide	Score	Method	ID	Site	Peptide	Score	Method
	YOR259C	117 Y	SEEKYIVKA	0.992	unsp	YOR259C	292 S	GRRFSEGTS	0.994	unsp

YOR259C | proteasome regulatory particle base subunit RPT4

ID's

UniProt_ID: P53549

GEO Functions

Computed_GO_Component_IDs: GO:0005737 GO:0000502

Computed_GO_Components: cytoplasm proteasome complex

Computed_GO_Function_IDs: GO:0005524 GO:0016787 GO:0000166

Computed_GO_Functions: ATP binding hydrolase activity nucleotide binding

Computed_GO_Process_IDs: GO:0030163

Computed_GO_Processes: protein catabolic process

Curated_GO_Component_IDs: GO:0031597 GO:0031595 GO:0005634 GO:0008540

Curated_GO_Components: cytosolic proteasome complex nuclear proteasome complex nucleus proteasome regulatory particle, base subcomplex

Curated_GO_Function_IDs: GO:0016887 GO:0017025 GO:0036402 GO:0019904 GO:0031625

Curated_GO_Functions: ATPase activity TBP-class protein binding proteasome-activating ATPase activity protein domain specific binding ubiquitin protein ligase binding

Curated_GO_Processes: nucleotide-excision repair positive regulation of RNA polymerase II transcriptional preinitiation complex assembly positive regulation of transcription elongation from RNA polymerase II promoter proteasome regulatory particle assembly ubiquitin-dependent ERAD pathway

Subcellular Localization

Targetp

Signalp

Fasta :-

Mitoprot

ProPeptide Prediction

Sequence

Nucleotide sequence

Fasta :-

Protein sequence

Fasta :-

Domains

CATH

Structure

Post Translational Modifications

N_Linked Glycosylation

O_Linked Glycosylation

Phosphorylation

Protein-Protein Interaction

String

YOR259C

Literature

PubMed

Google Scholar

Dinesh Gupta lab Translational bioinformatics group, ICGEB, New Delhi, India