• Thu. Dec 1st, 2022

Our Servers/Databases

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  • Our Servers/Databases

Our Research Technologies:-

The scientific interests of his Group include the use of computational biology tools to solve research problems in the post-genomic era.

  • Specifically, the group is interested in:-
    • Development and application of artificial intelligence-based methods to address complex biological data classification problems;
    • Computer-aided drug designing; including molecular modeling, molecular dynamics, homology modeling, virtual screening and cheminformatics for lead identification;
    • Application of comparative genomics methods to identify novel drug targets and gene expression regulatory elements like miRNAs and transcription factors;
    • Applications for Systems Biology for translational bioinformatics;
    • Computational and statistical analysis of NGS (Next Generation Sequence) data and;
    • Development of biological databases and algorithms.

Web Servers:-

  1. VirulentPred
  2. VsupPred – It is a SVM based webserver for predicting viral suppressor proteins.
  3. Duct-BRPA-CSP – BRCA-CSP (Breast cancer stage prediction) is a web-bench developed for predicting Early and Late stage of invasive ductal carcinoma (IDC) patients using gene expression data derived from RNA-seq experiments in the form of RNA-Seq by RPKM values.
  4. ASCoVPred: A web server to predict anti-SARS-CoV-2 activity and human cell toxicity of molecules
  5. ProtPathDB – A database for Pathogen and Parasite Proteases
  6. ApicoTFdb – Apicomplexans undergo a complex life cycle during its development across different tissues of vectors and host(s).
  7. CDKIPred:- CDKIPred is a SVM based prediction method to identify novel cellular CDK inhibitor proteins using various features of proteins.
  8. FaaPred:- Fungal adhesins and adhesin-like proteins prediction
  9. KiPho – Protein phosphorylation/dephosphorylation is one of the key Post-Translational Modifications (PTMs) process that is regulated by the kinases and phosphatases in the competitive manner.
  10. miRMOD:- miRNA modification prediction tool
  11. MirtronPred:- Introns are known to be a common source of canonical microRNAs.
  12. PAmiRDB is a database of computationally predicted whole genome viral targets of plant miRNA.
  13. plant VsupPred:- plant VsupPred is a Random Forest based prediction tool to predict viral Suppressors of RNA silencing (VSRs).
  14. PmiRNA – Micro RNAs (miRNAs) are small RNAs of about 20 to 24 nucleotides, which regulate post-transcriptional gene expression in plants and animals.
  15. PRmePRed – PRmePRed is an SVM based prediction tool to predict arginine methylation sites in proteins.
  16. CyclinpPred:- CyclinPred is a SVM based prediction method to identify novel cyclins using various features of proteins.
  17. AHPR – Present antiviral drugs against hepatitis are ineffective to deal with recent challenges of mixed, sporadic co-infections and cancer.
  18. APA:- Altered Pathway Analyzer (APA) is a cross-platform and standalone tool for analyzing gene expression datasets to highlight significantly rewired pathways across case-vs-control conditions.
  19. GFF-Ex:- A genome feature extraction package
  20. PSSM and SSC to SVM converter
  21. 20S iPred – 20S iPred webserver assists in the classification of compounds as 20S proteasome inhibitors or non-inhibitors.
  22. 20sPred – The ubiquitin/proteasome system plays a major role in overall protein turnover, in eukaryotic cells including plasmodia.
  23. 3DEpiPred- Identification of conformational B-cell epitopes in antigens is an important key step in rational vaccine design.
  24. DIREP:- Direct Repeats Web Server

Databases

  1. M3db- Meta-Analysis of Metastatic Melonama
  2. ProtvirDB:- A database of protozoan virulenProtvirDB: -t proteins

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